Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1.

abstract：BACKGROUND:Limited comparative studies assessing the health-related quality of life (HRQL) in heart failure (HF) patients with preserved vs. low ejection fraction (LVEF) have been disparate. AIMS:The aims of this study were a) to characterize HRQL in a large population of HF patients with preserved and low LVEF and b)...

journal_title：European journal of heart failure

authors： Lewis EF,Lamas GA,O'Meara E,Granger CB,Dunlap ME,McKelvie RS,Probstfield JL,Young JB,Michelson EL,Halling K,Carlsson J,Olofsson B,McMurray JJ,Yusuf S,Swedberg K,Pfeffer MA,CHARM Investigators.

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of NT-proBNP in the emergency diagnosis and in-hospital monitoring of patients with acute dyspnoea and ventricular dysfunction. BACKGROUND:Misdiagnosis of heart failure (HF) is common in the urgent care setting using clinical diagnostic tests. Reports show that BNP is useful to diagno...

journal_title：European journal of heart failure

authors： Bayés-Genís A,Santaló-Bel M,Zapico-Muñiz E,López L,Cotes C,Bellido J,Leta R,Casan P,Ordóñez-Llanos J

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Plasma levels of N-terminal pro-brain natriuretic peptide (NT-pro BNP) are increased in patients with chronic heart failure (CHF). Beta-blockers (BB) may influence these levels but it is unclear whether changes in NT-pro BNP reflect concomitant changes in prognosis. OBJECTIVES:To assess the prognostic impor...

journal_title：European journal of heart failure

authors： Olsson LG,Swedberg K,Cleland JG,Spark PA,Komajda M,Metra M,Torp-Pedersen C,Remme WJ,Scherhag A,Poole-Wilson P,COMET Investigators.

更新日期：2007-08-01 00:00:00

abstract：AIMS:Red cell distribution width (RDW) has been associated with cardiovascular disease, but the relation to heart failure (HF) is unclear. We investigated the association between RDW and incidence of first hospitalization due to HF in a population-based cohort. METHODS AND RESULTS:Red cell distribution width was measu...

journal_title：European journal of heart failure

authors： Borné Y,Smith JG,Melander O,Hedblad B,Engström G

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The EURObservational Research Programme is a rolling programme of cardiovascular registries and surveys of the European Society of Cardiology (ESC). These registries will provide information on the nature of cardiovascular disease and its management. This manuscript provides an update on new literature on pe...

journal_title：European journal of heart failure

authors： Sliwa K,Hilfiker-Kleiner D,Mebazaa A,Petrie MC,Maggioni AP,Regitz-Zagrosek V,Schaufelberger M,Tavazzi L,van Veldhuisen DJ,Roos-Hesslink JW,Shah AJ,Seferovic PM,Elkayam U,van Spaendonck-Zwarts K,Bachelier-Walenta K,Mouquet F

更新日期：2014-05-01 00:00:00

abstract：AIMS:Growth differentiation factor-15 (GDF-15) is associated with adverse prognosis in cardiovascular (CV) and non-CV diseases. We evaluated the association of GDF-15 with CV and non-CV outcomes in the PARADIGM-HF trial. METHODS AND RESULTS:In 1935 patients with heart failure and reduced ejection fraction (HFrEF) in P...

journal_title：European journal of heart failure

authors： Bouabdallaoui N,Claggett B,Zile MR,McMurray JJV,O'Meara E,Packer M,Prescott MF,Swedberg K,Solomon SD,Rouleau JL,PARADIGM-HF Investigators and Committees.

更新日期：2018-12-01 00:00:00

abstract：:Renal dysfunction in heart failure with preserved ejection fraction (HFpEF) is common and is associated with increased mortality. Impaired renal function is also a risk factor for developing HFpEF. A new paradigm for HFpEF, proposing a sequence of events leading to myocardial remodelling and dysfunction in HFpEF, was ...

journal_title：European journal of heart failure

authors： Ter Maaten JM,Damman K,Verhaar MC,Paulus WJ,Duncker DJ,Cheng C,van Heerebeek L,Hillege HL,Lam CS,Navis G,Voors AA

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The relationship between quality of life (QoL) and survival have been poorly investigated. The aim of this study was to determine the value of QoL score as a prognostic factor in a prospective cohort of patients with advanced chronic heart failure (CHF). METHODS:QoL assessment was performed with a generic q...

journal_title：European journal of heart failure

authors： Alla F,Briançon S,Guillemin F,Juillière Y,Mertès PM,Villemot JP,Zannad F,EPICAL Investigators.

更新日期：2002-06-01 00:00:00

abstract：AIMS:Congestive heart failure (CHF) is associated with impaired renal function. Previously, we have demonstrated that rats with decompensated CHF exhibited exaggerated sensitivity to the adverse renal effects of increased increased intra-abdominal pressure (IAP) as compared with normal controls. This study tested wheth...

journal_title：European journal of heart failure

authors： Bishara B,Abu-Saleh N,Awad H,Ghrayeb N,Goltsman I,Aronson D,Khamaysi I,Assady S,Armaly Z,Haddad S,Haddad E,Abassi Z

更新日期：2012-10-01 00:00:00

abstract：AIMS:Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and prognostic value of RV dysfunction in HFpEF have been widely but variably reported. We therefore conducted a systematic review and meta-analys...

journal_title：European journal of heart failure

authors： Gorter TM,Hoendermis ES,van Veldhuisen DJ,Voors AA,Lam CS,Geelhoed B,Willems TP,van Melle JP

更新日期：2016-12-01 00:00:00

abstract：AIMS:Remote patient management (telemonitoring) may help to detect early signs of cardiac decompensation, allowing optimization of and adherence to treatments in chronic heart failure (CHF). Two meta-analyses have suggested that telemedicine in CHF can reduce mortality by 30-35%. The aim of the TIM-HF study was to inve...

journal_title：European journal of heart failure

authors： Koehler F,Winkler S,Schieber M,Sechtem U,Stangl K,Böhm M,Boll H,Kim SS,Koehler K,Lücke S,Honold M,Heinze P,Schweizer T,Braecklein M,Kirwan BA,Gelbrich G,Anker SD,TIM-HF Investigators.

更新日期：2010-12-01 00:00:00

abstract：AIMS:Acute heart failure is a high mortality disease and its pathophysiology is not completely understood. Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in angiotensin II and enkephalins cleavage. The aim of this study was to investigate the association of circulating DPP3 (cDPP3) levels and mortality in...

journal_title：European journal of heart failure

authors： Deniau B,Rehfeld L,Santos K,Dienelt A,Azibani F,Sadoune M,Kounde PR,Samuel JL,Tolpannen H,Lassus J,Harjola VP,Vodovar N,Bergmann A,Hartmann O,Mebazaa A,Blet A

更新日期：2020-02-01 00:00:00

abstract：AIMS:The prognostic value of signs of congestion in patients suspected of having chronic heart failure (CHF) is unknown. Our objectives were to define their prevalence and specificity in diagnosing CHF and to determine their prognostic value in patients in a community heart failure clinic. METHODS AND RESULTS:Analysis...

journal_title：European journal of heart failure

authors： Damy T,Kallvikbacka-Bennett A,Zhang J,Goode K,Buga L,Hobkirk J,Yassin A,Dubois-Randé JL,Hittinger L,Cleland JG,Clark AL

更新日期：2011-12-01 00:00:00

abstract：AIMS:Urine proteome analysis (UPA) has already provided accurate discriminatory patterns of urinary peptides for renal disease, coronary artery disease, and asymptomatic LV diastolic dysfunction. UPA has now been used to characterize a discriminatory peptide biomarker pattern and establish a diagnostic classifier for h...

journal_title：European journal of heart failure

authors： Farmakis D,Koeck T,Mullen W,Parissis J,Gogas BD,Nikolaou M,Lekakis J,Mischak H,Filippatos G

更新日期：2016-07-01 00:00:00

abstract：AIMS:To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). METHODS AND RESULTS:A 5-day open-label run-in (sacubitril/valsartan 50 mg twice daily) preceded an 11-week, dou...

journal_title：European journal of heart failure

authors： Senni M,McMurray JJ,Wachter R,McIntyre HF,Reyes A,Majercak I,Andreka P,Shehova-Yankova N,Anand I,Yilmaz MB,Gogia H,Martinez-Selles M,Fischer S,Zilahi Z,Cosmi F,Gelev V,Galve E,Gómez-Doblas JJ,Nociar J,Radomska M,S

更新日期：2016-09-01 00:00:00

abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

journal_title：European journal of heart failure

authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The adipocyte-specific cytokine adiponectin, has cardioprotective effects, correlates with endogenous cardiac natriuretic peptides and adipocyte has guanylyl cyclase-A receptors of natriuretic peptides. AIMS:To evaluate the effect of carperitide (atrial natriuretic peptide; ANP) on plasma adiponectin in pat...

journal_title：European journal of heart failure

authors： Tanaka T,Tsutamoto T,Sakai H,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Biventricular (BiV) pacing has been found to improve systolic function and exercise tolerance in patients with severe congestive heart failure and bundle branch block. The mechanisms behind this beneficial effect is still not sufficiently clarified. AIM:To evaluate the regional myocardial perfusion (MP) dur...

journal_title：European journal of heart failure

authors： Nielsen JC,Bøttcher M,Jensen HK,Nielsen TT,Pedersen AK,Mortensen PT

更新日期：2003-03-01 00:00:00

abstract：AIMS:Psychopathologies may occur in heart failure (HF) and can be associated with adverse outcomes. Amongst neuropeptide S receptor gene functional sequence variants, the T-allele [asparagine(107)isoleucine, NPSR1 rs324981] has been identified as a risk factor for increased anxiety/overinterpretation of bodily symptoms...

journal_title：European journal of heart failure

authors： Angermann CE,Kaspar M,Marx A,Kittel-Schneider S,Menhofer D,Störk S,Ertl G,Domschke K,Deckert J,Reif A

更新日期：2017-03-01 00:00:00

abstract：UNLABELLED:We compare the effectiveness of direct adenoviral angiopoietin-1 (Ad-Ang-1) injection with transplantation of skeletal myoblasts (SkMs) over-expressing angiopoietin-1 (Ang-1) for angiogenic response and improvement of heart function in an experimental porcine model of myocardial infarction (MI). METHODS:Ad-...

journal_title：European journal of heart failure

authors： Ye L,Haider HKh,Jiang S,Tan RS,Toh WC,Ge R,Sim EK

更新日期：2007-05-01 00:00:00

abstract：AIMS:The most recent European guidelines have proposed new definitions of pulmonary hypertension (PH) in left heart disease, to better approach the characteristics required to reflect the presence of pulmonary vascular disease. The purpose of this study was to assess whether different haemodynamic definitions of post-c...

journal_title：European journal of heart failure

authors： Ghio S,Crimi G,Temporelli PL,Traversi E,La Rovere MT,Cannito A,Vizza D,Scelsi L,Raineri C,Guazzi M,Oltrona Visconti L

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:In acute heart failure syndromes (AHFS), the prognostic value of left ventricular ejection fraction (LVEF), although widely accepted, has been recently challenged. In contrast, blood pressure is increasingly gaining ground over LVEF as predictor of mortality. Therefore, it is not clear whether both LVEF and ...

journal_title：European journal of heart failure

authors： Adamopoulos C,Zannad F,Fay R,Mebazaa A,Cohen-Solal A,Guize L,Juillière Y,Alla F

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To study changes in connexin, metalloproteinase and tissue inhibitor of metalloproteinase levels during tachycardia-induced cardiomyopathy (TIC). METHODS:Canine models of TIC were established by rapid right atrial pacing at 350-400 beats per min for 8 weeks in 11 dogs, six dogs acted as a sham operation grou...

journal_title：European journal of heart failure

authors： Zhong JQ,Zhang W,Gao H,Li Y,Zhong M,Li D,Zhang C,Zhang Y

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...

journal_title：European journal of heart failure

authors： Kronborg MB,Mortensen PT,Kirkfeldt RE,Nielsen JC

更新日期：2008-08-01 00:00:00

abstract：:We investigated the hypothesis that increased intracellular [Na+]i in heart failure contributes to preservation of SR Ca2+ load which may become particularly evident at slow heart rates. [Na+]i in SBFI-loaded myocytes from rabbits with pacing-induced heart failure (PHF) was significantly higher at each frequency as co...

journal_title：European journal of heart failure

authors： Schillinger W,Teucher N,Christians C,Kohlhaas M,Sossalla S,Van Nguyen P,Schmidt AG,Schunck O,Nebendahl K,Maier LS,Zeitz O,Hasenfuss G

更新日期：2006-11-01 00:00:00

abstract：AIMS:Several studies have shown that older patients with heart failure with reduced ejection fraction (HFrEF) are undertreated. The aim of this study was to evaluate the association of up-titration of angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB) and beta-blockers on outcome acros...

journal_title：European journal of heart failure

authors： Mordi IR,Ouwerkerk W,Anker SD,Cleland JG,Dickstein K,Metra M,Ng LL,Samani NJ,van Veldhuisen DJ,Zannad F,Voors AA,Lang CC

更新日期：2020-03-25 00:00:00

abstract：AIMS:Chronic heart failure (CHF) is associated with a higher risk for diabetes mellitus. Retinol binding protein 4 (RBP 4) is an adipose tissue-derived protein with pro-diabetogenic effects. A complete understanding of the association of CHF and insulin resistance remains elusive. The purpose of this study was to exami...

journal_title：European journal of heart failure

authors： Bobbert P,Weithäuser A,Andres J,Bobbert T,Kühl U,Schultheiss HP,Rauch U,Skurk C

更新日期：2009-12-01 00:00:00

abstract：AIM:Heart failure with preserved ejection fraction (HFpEF) is associated with increased sympathetic nervous system (SNS) tone. Attenuating the SNS with renal denervation (RDT) might be helpful and there are no data currently in humans with HFpEF. METHODS AND RESULTS:In this single-centre, randomized, open-controlled s...

journal_title：European journal of heart failure

authors： Patel HC,Rosen SD,Hayward C,Vassiliou V,Smith GC,Wage RR,Bailey J,Rajani R,Lindsay AC,Pennell DJ,Underwood SR,Prasad SK,Mohiaddin R,Gibbs JS,Lyon AR,Di Mario C

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:It has been suggested that oxidative stress may play a role in the pathogenesis of heart failure, this may have potential implications for therapeutic strategies. However, measures of oxidative stress are subject to confounding inaccuracies. IgG antibodies to oxidized LDL reflect exposure to the lipoprotein ...

journal_title：European journal of heart failure

authors： George J,Wexler D,Roth A,Barak T,Sheps D,Keren G

更新日期：2006-01-01 00:00:00

abstract：:Transthyretin amyloidosis (ATTR) is a rare, yet underdiagnosed disease characterized by progressive impairment of neurologic and cardiac function due to deposition of misfolded transthyretin. Despite great efforts, such as the introduction of orthotopic liver transplant, the devastating prognosis for both variant and ...

journal_title：European journal of heart failure

authors： Müller ML,Butler J,Heidecker B

更新日期：2020-01-01 00:00:00