Design of the heart failure endpoint evaluation of AII-antagonist losartan (HEAAL) study in patients intolerant to ACE-inhibitor.

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：AIMS:A restrictive transmitral filling (RF) pattern predicts increased mortality in heart failure (HF) with reduced left ventricular (LV) systolic function. We performed a combined evaluation of LV function and RF for prognosis in patients with HF with and without systolic dysfunction. METHODS AND RESULTS:Doppler echo...

journal_title：European journal of heart failure

authors： Akkan D,Kjaergaard J,Møller JE,Hassager C,Torp-Pedersen C,Køber L,EchoCardiography and Heart Outcome Study (ECHOS) investigators.

更新日期：2008-07-01 00:00:00

abstract：AIMS:The objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial oxygen saturation, increases respiratory rate and pulmonary artery pres...

journal_title：European journal of heart failure

authors： Hobkirk JP,Damy T,Walters M,Bennett A,Smith SJ,Ingle L,Clark AL,Cleland JG

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The role of the right ventricle has been relatively neglected proportionate to its importance. We sought to evaluate the impact of right ventricular (RV) and NT-proBNP on the outcome of patients with heart failure (HF) and functional mitral regurgitation (MR). METHODS AND PATIENTS:Outpatients with left vent...

journal_title：European journal of heart failure

authors： Dini FL,Fontanive P,Panicucci E,Andreini D,Chella P,De Tommasi SM

更新日期：2008-06-01 00:00:00

abstract：AIMS:Chronic hypertension may cause left ventricular hypertrophy (LVH). The role of matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), and tenascin-C (Tn-C) splice variants in concentric vs. eccentric left ventricular remodelling has not been investigated. METHODS AND RESULTS:Ser...

journal_title：European journal of heart failure

authors： Franz M,Berndt A,Altendorf-Hofmann A,Fiedler N,Richter P,Schumm J,Fritzenwanger M,Figulla HR,Brehm BR

更新日期：2009-11-01 00:00:00

abstract：:Ventricular assist device implantation has become an established therapy in adults and children for bridging to heart transplantation or to aid myocardial recovery. Recently, implantation of left ventricular assist devices as definitive therapy has been recognized as a better option than pharmacological treatment in p...

journal_title：European journal of heart failure

authors： Potapov EV,Jurmann MJ,Drews T,Pasic M,Loebe M,Weng Y,Hetzer R

更新日期：2006-11-01 00:00:00

abstract：AIMS:Despite improvement in prognosis for ST-elevation myocardial infarction (STEMI) patients, mortality remains high in STEMI patients presenting with cardiogenic shock (CS). Right ventricular (RV) dysfunction is an established independent predictor for adverse prognosis in STEMI patients without CS. The purpose of ou...

journal_title：European journal of heart failure

authors： Engström AE,Vis MM,Bouma BJ,van den Brink RB,Baan J Jr,Claessen BE,Kikkert WJ,Sjauw KD,Meuwissen M,Koch KT,de Winter RJ,Tijssen JG,Piek JJ,Henriques JP

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Knowledge on clinical characteristics and prognosis of patients with heart failure originates from studies of selected populations in clinical trials or from epidemiological observations. Reports on the large numbers of patients with heart failure treated in community hospitals are sparse. OBJECTIVE:Are the...

journal_title：European journal of heart failure

authors： Taubert G,Bergmeier C,Andresen H,Senges J,Potratz J

更新日期：2001-10-01 00:00:00

abstract：AIMS:The present study aimed to assess the association between left atrial (LA) structure and function and the risk for cardiovascular (CV) death or heart failure (HF) hospitalization in a population with atrial fibrillation (AF). METHODS AND RESULTS:In a prospective echocardiographic substudy of the Effective Anticoa...

journal_title：European journal of heart failure

authors： Inciardi RM,Giugliano RP,Claggett B,Gupta DK,Chandra A,Ruff CT,Antman EM,Mercuri MF,Grosso MA,Braunwald E,Solomon SD,ENGAGE AF-TIMI 48 Investigators.

更新日期：2019-12-01 00:00:00

abstract：AIMS:Patients with acute heart failure (HF) in Africa are rarely being treated with a hydralazine/nitrates combination. Therefore the effect of this treatment was studied here. METHODS AND RESULTS:The study was planned to enrol 500 patients during an acute HF admission, from nine sub-Saharan African countries. Patient...

journal_title：European journal of heart failure

authors： Sliwa K,Damasceno A,Davison BA,Mayosi BM,Sani MU,Ogah O,Mondo C,Ojji D,Dzudie A,Kouam CK,Yonga G,Ba SA,Ogola E,Edwards C,Milo O,Cotter G

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:It is not clear if long-term antithrombotic treatment has a beneficial effect on the incidence of thromboembolism in chronic heart failure (CHF). The HELAS study (Heart failure Long-term Antithrombotic Study) is a multicentre, randomised, double-blind, placebo-controlled trial to evaluate antithrombotic trea...

journal_title：European journal of heart failure

authors： Cokkinos DV,Haralabopoulos GC,Kostis JB,Toutouzas PK,HELAS investigators.

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:In most animal models of chronic hemodynamic overload of the left ventricle (LV) as well as in human end stage heart failure, the sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) mRNA levels are decreased in parallel with increased atrial natriuretic peptide (ANP) mRNA levels. The situation in the remote my...

journal_title：European journal of heart failure

authors： Prunier F,Chen Y,Gellen B,Heimburger M,Choqueux C,Escoubet B,Michel JB,Mercadier JJ

更新日期：2005-08-01 00:00:00

abstract：AIMS:To investigate the annual hospitalization rate and seasonal variation in confirmed heart failure (HF) admissions. METHODS AND RESULTS:Records from all admissions to one hospital during 1 year with a HF diagnostic code were reviewed. From 1953 admissions, 595 were excluded because they did not fulfill the diagnost...

journal_title：European journal of heart failure

authors： Martínez-Sellés M,García Robles JA,Prieto L,Serrano JA,Muñoz R,Frades E,Almendral J

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:We compare the effectiveness of direct adenoviral angiopoietin-1 (Ad-Ang-1) injection with transplantation of skeletal myoblasts (SkMs) over-expressing angiopoietin-1 (Ang-1) for angiogenic response and improvement of heart function in an experimental porcine model of myocardial infarction (MI). METHODS:Ad-...

journal_title：European journal of heart failure

authors： Ye L,Haider HKh,Jiang S,Tan RS,Toh WC,Ge R,Sim EK

更新日期：2007-05-01 00:00:00

abstract：AIMS:Knowledge of patient preferences is vital for delivering optimal healthcare. This study uses utility measurement to assess the preferences of heart failure (HF) patients regarding quality of life or longevity. The utility approach represents the perspective of a patient; facilitates the combination of mortality, m...

journal_title：European journal of heart failure

authors： Kraai IH,Vermeulen KM,Luttik ML,Hoekstra T,Jaarsma T,Hillege HL

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Information about the occurrence of heart failure in the acute phase of myocardial infarction (MI) in diabetic patients and its impact on prognosis are sparse. AIM:The purpose of the present study was to describe how MI patients with diabetes mellitus (DM) differed from MI patients without DM with respect t...

journal_title：European journal of heart failure

authors： Melchior T,Rask-Madsen C,Torp-Pedersen C,Hildebrandt P,Køber L,Jensen G

更新日期：2001-01-01 00:00:00

abstract：AIMS:Right ventricular (RV) dysfunction has been associated with a worse outcome in heart failure patients undergoing CRT. However, evidence on the RV response to CRT is controversial and there are no data regarding the early effects of CRT on RV function (RVF). We sought to investigate whether a CRT device favourably ...

journal_title：European journal of heart failure

authors： Stolfo D,Tonet E,Merlo M,Barbati G,Gigli M,Pinamonti B,Ramani F,Zecchin M,Sinagra G

更新日期：2016-02-01 00:00:00

abstract：AIMS:Insulin-dependent positive inotropic effects (PIE) are partially Ca(2+) independent. This mechanism is potentially glucose dependent. In contrast to most animal species, human myocardium expresses high levels of sodium-glucose-transporter-1 (SGLT-1) mRNA besides the common glucose-transporters-1 and -4 (GLUT1, GLU...

journal_title：European journal of heart failure

authors： von Lewinski D,Gasser R,Rainer PP,Huber MS,Wilhelm B,Roessl U,Haas T,Wasler A,Grimm M,Bisping E,Pieske B

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The epidemiology of heart failure in Arabia, with a population different from the West in cultural and ethnic origin, has not been studied before. AIMS:To determine the prevalence and aetiologies of symptomatic heart failure in an indigenous Arab population over a 3-year period. METHODS:All patients with h...

journal_title：European journal of heart failure

authors： Agarwal AK,Venugopalan P,de Bono D

更新日期：2001-06-01 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a measure of acute kidney injury. Renal dysfunction portends significant risk after discharge from acute heart failure (AHF). Thus, a sensitive marker of renal injury might also help to risk stratify HF patients. METHODS AND RESULTS:GALLANT [NGAL EvaLuation Alo...

journal_title：European journal of heart failure

authors： Maisel AS,Mueller C,Fitzgerald R,Brikhan R,Hiestand BC,Iqbal N,Clopton P,van Veldhuisen DJ

更新日期：2011-08-01 00:00:00

abstract：AIMS:To examine the impact of diabetes mellitus on long-term clinical outcomes in patients with myocardial infarction (MI) complicated by clinical signs of heart failure (HF) or left ventricular dysfunction (LVD). METHODS AND RESULTS:The High-Risk MI Database consists of individual data from 28 771 patients and was cr...

journal_title：European journal of heart failure

authors： Tajik AA,Dobre D,Aguilar D,Kjekshus J,Zannad F,Dickstein K,High-Risk MI Database Scientific Committee.

更新日期：2017-05-01 00:00:00

abstract：AIMS:To determine whether a strategy of intensive blood pressure control reduces the risk of heart failure (HF) events consistently across the spectrum of kidney function and albuminuria. METHODS AND RESULTS:SPRINT was a randomized clinical trial in which 9361 individuals ≥50 years, at high risk for or with cardiovasc...

journal_title：European journal of heart failure

authors： Vaduganathan M,Pareek M,Kristensen AMD,Biering-Sørensen T,Byrne C,Almarzooq Z,Olesen TB,Olsen MH,Bhatt DL

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Cardiac angiotensin converting enzyme (ACE) is activated by an increase in wall stress and is involved in remodeling processes. Heart failure is often treated with ACE inhibitors and diuretics although diuretic treatment could activate the renin-angiotensin system (RAS). AIMS:To examine the effects of diure...

journal_title：European journal of heart failure

authors： Seeland U,Kouchi I,Zolk O,Jockenhövel F,Itter G,Linz W,Böhm M

更新日期：2003-06-01 00:00:00

abstract：:Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies u...

journal_title：European journal of heart failure

authors： Dahlström U

更新日期：2005-03-16 00:00:00

abstract：AIMS:To assess cardiac gene expression in peripheral blood cells of patients with idiopathic dilated cardiomyopathy (IDCM) and its relationship to echocardiographic left ventricular (LV) function. METHODS AND RESULTS:A complete echocardiographic study and blood sampling were performed in 65 consecutive stable IDCM pat...

journal_title：European journal of heart failure

authors： Kontaraki JE,Parthenakis FI,Nyktari EG,Patrianakos AP,Vardas PE

更新日期：2010-06-01 00:00:00

abstract：:This article provides information and a commentary on trials presented at the American Heart Association meeting held in November 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports should be considered as preliminary data, as analyses may change in the final publication. In R...

journal_title：European journal of heart failure

authors： Cleland JG,Freemantle N,Coletta AP,Clark AL

更新日期：2006-01-01 00:00:00

abstract：:The incidence and prevalence of cardiovascular disease increases progressively with advancing age. Cardiovascular disease is a major cause of morbidity and mortality in Western Countries. In the near future, as the population ages, it is expected that the population prevalence of cardiovascular disease will increase d...

journal_title：European journal of heart failure

authors： Wong LS,de Boer RA,Samani NJ,van Veldhuisen DJ,van der Harst P

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Sleep disordered breathing (SDB), especially Cheyne-Stokes respiration (CSR) is common in patients with chronic heart failure (CHF). Adaptive servoventilation (ASV) was recently introduced to treat CSR in CHF. The aim of this study was to investigate the effects of ASV on CSR and CHF parameters. ME...

journal_title：European journal of heart failure

authors： Oldenburg O,Schmidt A,Lamp B,Bitter T,Muntean BG,Langer C,Horstkotte D

更新日期：2008-06-01 00:00:00

abstract：AIMS:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support stabilizes patients with cardiogenic shock. Despite improved oxygenation and peripheral circulation, LV unloading may be impeded due to the increased afterload, resulting in a failing static left ventricle and in high mortality. METHODS AND RESUL...

journal_title：European journal of heart failure

authors： Pappalardo F,Schulte C,Pieri M,Schrage B,Contri R,Soeffker G,Greco T,Lembo R,Müllerleile K,Colombo A,Sydow K,De Bonis M,Wagner F,Reichenspurner H,Blankenberg S,Zangrillo A,Westermann D

更新日期：2017-03-01 00:00:00

abstract：:Carvedilol has been shown to be beneficial for patients with heart failure, but it is not clear how it should be initiated in routine clinical practice, particularly in the elderly. This study is a retrospective review of 19 patients of age 80+/-4 years with heart failure, who had Carvedilol treatment initiated in a r...

journal_title：European journal of heart failure

authors： Owen A

更新日期：2000-09-01 00:00:00