Effects of diuretic treatment on cardiac and circulating RAS in chronic heart failure post-myocardial infarction in rats.

abstract：BACKGROUND:Heart failure with preserved or mildly reduced ejection fraction (HFpEF) is common and, to date, therapeutic options are limited. Increased left atrial pressure is a key contributor to the symptoms associated with HFpEF, particularly during physical activity. We report the 30-day outcome of patients treated ...

journal_title：European journal of heart failure

authors： Søndergaard L,Reddy V,Kaye D,Malek F,Walton A,Mates M,Franzen O,Neuzil P,Ihlemann N,Gustafsson F

更新日期：2014-07-01 00:00:00

abstract：AIMS:We sought to describe the frequency, type and timing of clinical events, and delineate patterns in their transitions, after a first episode of heart failure (HF). METHODS AND RESULTS:In 1036 Framingham participants with new-onset HF (mean age 79 years; 53% women), we used mixture models to estimate probabilities ...

journal_title：European journal of heart failure

authors： Velagaleti RS,Larson MG,Enserro D,Song RJ,Vasan RS

更新日期：2020-10-01 00:00:00

abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...

journal_title：European journal of heart failure

authors： Miller WL,Borgeson DD,Grantham JA,Luchner A,Redfield MM,Burnett JC Jr

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is a global public health problem. Unfortunately, little is known about HFpEF across Asia. METHODS AND RESULTS:We prospectively studied clinical characteristics, echocardiographic parameters and outcomes in 1204 patients with HFpEF (left ventricular eje...

journal_title：European journal of heart failure

authors： Tromp J,Teng TH,Tay WT,Hung CL,Narasimhan C,Shimizu W,Park SW,Liew HB,Ngarmukos T,Reyes EB,Siswanto BB,Yu CM,Zhang S,Yap J,MacDonald M,Ling LH,Leineweber K,Richards AM,Zile MR,Anand IS,Lam CSP,ASIAN-HF Investiga

更新日期：2019-01-01 00:00:00

abstract：AIMS:Reliable detectors of worsening renal function (WRF) in Emergency Department (ED) patients with acute heart failure (AHF) are limited. We hypothesized that initial urinary neutrophil gelatinase-associated lipocalcin (NGAL) levels, and changes in urinary NGAL levels after initial ED AHF therapy, would be associated...

journal_title：European journal of heart failure

authors： Collins SP,Hart KW,Lindsell CJ,Fermann GJ,Weintraub NL,Miller KF,Roll SN,Sperling MI,Sawyer DB,Storrow AB

更新日期：2012-09-01 00:00:00

abstract：:COMBAT is a prospective, multicenter, randomized, blinded clinical study, with crossover design. The main objective is the comparative evaluation of atrio-biventricular versus conventional atrioventricular stimulation (atrio and right ventricle) in patients with heart failure and bradycardia as the primary indication ...

journal_title：European journal of heart failure

authors： Martinelli M,Costa R,de Siqueira SF,Ramires JA

更新日期：2005-03-02 00:00:00

abstract：BACKGROUND:Crataegus preparations have been used for centuries especially in Europe. To date, no proper data on their efficacy and safety as an add-on-treatment are available. Therefore a large morbidity/mortality trial was performed. AIM:To investigate the efficacy and safety of an add-on treatment with Crataegus ext...

journal_title：European journal of heart failure

authors： Holubarsch CJ,Colucci WS,Meinertz T,Gaus W,Tendera M,Survival and Prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group.

更新日期：2008-12-01 00:00:00

abstract：AIMS:To assess cardiac gene expression in peripheral blood cells of patients with idiopathic dilated cardiomyopathy (IDCM) and its relationship to echocardiographic left ventricular (LV) function. METHODS AND RESULTS:A complete echocardiographic study and blood sampling were performed in 65 consecutive stable IDCM pat...

journal_title：European journal of heart failure

authors： Kontaraki JE,Parthenakis FI,Nyktari EG,Patrianakos AP,Vardas PE

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：AIMS:In the Digitalis Investigation Group (DIG) trial, digoxin reduced mortality or hospitalization due to heart failure (HF) in several pre-specified high-risk subgroups of HF patients, but data on protocol-specified 2-year outcomes were not presented. In the current study, we examined the effect of digoxin on HF deat...

journal_title：European journal of heart failure

authors： Gheorghiade M,Patel K,Filippatos G,Anker SD,van Veldhuisen DJ,Cleland JG,Metra M,Aban IB,Greene SJ,Adams KF,McMurray JJ,Ahmed A

更新日期：2013-05-01 00:00:00

abstract：AIMS:The aim of this study was to investigate the clinical picture and outcome of cardiogenic shock and to develop a risk prediction score for short-term mortality. METHODS AND RESULTS:The CardShock study was a multicentre, prospective, observational study conducted between 2010 and 2012. Patients with either acute co...

journal_title：European journal of heart failure

authors： Harjola VP,Lassus J,Sionis A,Køber L,Tarvasmäki T,Spinar J,Parissis J,Banaszewski M,Silva-Cardoso J,Carubelli V,Di Somma S,Tolppanen H,Zeymer U,Thiele H,Nieminen MS,Mebazaa A,CardShock Study Investigators.,GREAT network

更新日期：2015-05-01 00:00:00

abstract：:Most treatments for chronic heart failure are effective both in preventing its onset and reducing its progression. However, statins prevent the development of heart failure, but they do not decrease morbidity and mortality in those with established heart failure. This apparent discordance cannot be explained by an eff...

journal_title：European journal of heart failure

authors： Packer M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:No specific guidelines exist on how to manage renal dysfunction (RD) in patients with chronic heart failure (CHF). AIMS:To identify the proportion of patients with moderate to severe RD and CHF who showed an improvement in their renal function in response to a systematic management algorithm. METHODS:Stabl...

journal_title：European journal of heart failure

authors： de Silva R,Nikitin NP,Witte KK,Rigby AS,Loh H,Nicholson A,Bhandari S,Clark AL,Cleland JG

更新日期：2007-04-01 00:00:00

abstract：:Patients with heart failure (HF) are at an increased risk of stroke, sudden death and venous thromboembolism, which are all linked to thrombus formation (thrombogenesis). The present 'viewpoint' article will discuss how the prothrombotic state in HF may be perpetuated by a chronic inflammatory state that is maladaptiv...

journal_title：European journal of heart failure

authors： Chong AY,Lip GY

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:It is not clear if long-term antithrombotic treatment has a beneficial effect on the incidence of thromboembolism in chronic heart failure (CHF). The HELAS study (Heart failure Long-term Antithrombotic Study) is a multicentre, randomised, double-blind, placebo-controlled trial to evaluate antithrombotic trea...

journal_title：European journal of heart failure

authors： Cokkinos DV,Haralabopoulos GC,Kostis JB,Toutouzas PK,HELAS investigators.

更新日期：2006-06-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the efficacy of adding the beta-blocker bucindolol to standard therapy shortly after a myocardial infarction in a high-risk population with reduced left ventricular function. METHODS:The study was planned to include 2000 patients with an enzyme confirmed myocardial infa...

journal_title：European journal of heart failure

authors： Torp-Pedersen C,Køber L,Ball S,Hall A,Brendorp B,Ottesen M,Berning J,Jensen G,Hampton J,Zilles P,Eberle S,Carlsen J

更新日期：2002-08-01 00:00:00

abstract：:Heart failure and sleep apnoea are major health problems with an increasingly recognized association; evidence suggests that sleep apnoea may play a role in the progression of heart failure. However, confounding factors such as obesity, hypertension and coronary heart disease make this relationship uncertain and an in...

journal_title：European journal of heart failure

authors： Ferreira S,Winck J,Bettencourt P,Rocha-Goncalves F

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The angiotensin II type 2 (AT2) receptor is thought to play a role in cardiovascular disorders such as neointima formation after vascular injury, cardiac hypertrophy and myocardial infarction (MI). Recently, the biallelic polymorphism G + 1675A in intron 1 of the AT2 receptor gene has been associated with le...

journal_title：European journal of heart failure

authors： Herrmann SM,Nicaud V,Schmidt-Petersen K,Pfeifer J,Erdmann J,McDonagh T,Dargie HJ,Paul M,Regitz-Zagrosek V

更新日期：2002-12-01 00:00:00

abstract：AIMS:Clinical presentation of takotsubo syndrome (TTS) mimics acute coronary syndrome (ACS) and does not allow differentiation. We aimed to develop a clinical score to estimate the probability of TTS and to distinguish TTS from ACS in the acute stage. METHODS AND RESULTS:Patients with TTS were recruited from the Inter...

journal_title：European journal of heart failure

authors： Ghadri JR,Cammann VL,Jurisic S,Seifert B,Napp LC,Diekmann J,Bataiosu DR,D'Ascenzo F,Ding KJ,Sarcon A,Kazemian E,Birri T,Ruschitzka F,Lüscher TF,Templin C,InterTAK co-investigators.

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:In patients with heart failure and reduced left ventricular ejection fraction, angiotensin receptor blockers have been found to reduce mortality and morbidity and to prevent or reverse left ventricular remodelling, compared to optimized background treatment. In light of these data, The Heart failure Endpoint...

journal_title：European journal of heart failure

authors： Konstam MA,Poole-Wilson PA,Dickstein K,Drexler H,Justice SJ,Komajda M,Malbecq W,Martinez FA,Neaton JD,Riegger GA,Guptha S

更新日期：2008-09-01 00:00:00

abstract：AIMS:To investigate the relationship between decongestion, central venous pressure, and risk of worsening renal function (WRF) in patients with acute decompensated heart failure (ADHF). METHODS AND RESULTS:We studied 475 patients with ADHF, of whom 238 underwent right heart catheterization. Right atrial pressure (RAP)...

journal_title：European journal of heart failure

authors： Aronson D,Abassi Z,Allon E,Burger AJ

更新日期：2013-06-01 00:00:00

abstract：AIMS:The true incidence of life-threatening ventricular tachyarrhythmic events and the risk of sudden cardiac death in the early stage of peripartum cardiomyopathy (PPCM) are still unknown. We aimed to assess the usefulness of the wearable cardioverter/defibrillator (WCD) to bridge a potential risk for life-threatening...

journal_title：European journal of heart failure

authors： Duncker D,Haghikia A,König T,Hohmann S,Gutleben KJ,Westenfeld R,Oswald H,Klein H,Bauersachs J,Hilfiker-Kleiner D,Veltmann C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among heart failure patients and it is possible that high-risk subgroups may benefit from...

journal_title：European journal of heart failure

authors： Goudie A,Elder D,Deshmukh H,Szwejkowski BR,Lang CC,George J

更新日期：2015-01-01 00:00:00

abstract：AIMS:To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). METHODS AND RESULTS:A 5-day open-label run-in (sacubitril/valsartan 50 mg twice daily) preceded an 11-week, dou...

journal_title：European journal of heart failure

authors： Senni M,McMurray JJ,Wachter R,McIntyre HF,Reyes A,Majercak I,Andreka P,Shehova-Yankova N,Anand I,Yilmaz MB,Gogia H,Martinez-Selles M,Fischer S,Zilahi Z,Cosmi F,Gelev V,Galve E,Gómez-Doblas JJ,Nociar J,Radomska M,S

更新日期：2016-09-01 00:00:00

abstract：AIMS:The Home or Hospital in Heart failure (HHH) study was a European Community-funded, multinational, randomized controlled clinical trial, conducted in the UK, Poland, and Italy, to assess the feasibility of a new system of home telemonitoring (HT). The HT system was used to monitor clinical and physiological paramet...

journal_title：European journal of heart failure

authors： Mortara A,Pinna GD,Johnson P,Maestri R,Capomolla S,La Rovere MT,Ponikowski P,Tavazzi L,Sleight P,HHH Investigators.

更新日期：2009-03-01 00:00:00

abstract：AIMS:Incident heart failure (HF) continues to pose a common and serious problem. We sought to examine the value of echocardiographic predictors of new HF in a community-based elderly population at risk for HF, independent of and incremental to clinical evaluation. METHODS AND RESULTS:Asymptomatic patients ≥65 years ol...

journal_title：European journal of heart failure

authors： Yang H,Negishi K,Wang Y,Nolan M,Saito M,Marwick TH

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...

journal_title：European journal of heart failure

authors： Corell P,Gustafsson F,Schou M,Markenvard J,Nielsen T,Hildebrandt P

更新日期：2007-03-01 00:00:00

abstract：AIMS:The primary objective of this systematic review was to estimate the prevalence and temporal changes in chronic comorbid conditions reported in heart failure (HF) clinical trials. METHODS AND RESULTS:We searched MEDLINE for HF trials enrolling more than 400 patients published between 2001 and 2016.Trials were divi...

journal_title：European journal of heart failure

authors： Khan MS,Samman Tahhan A,Vaduganathan M,Greene SJ,Alrohaibani A,Anker SD,Vardeny O,Fonarow GC,Butler J

更新日期：2020-06-01 00:00:00

abstract：AIMS:Mutations in the lamin A/C gene (LMNA) cause a variety of clinical phenotypes, including dilated cardiomyopathy. LMNA is one of the most prevalent mutated genes in dilated cardiomyopathy, and is associated with a high risk of arrhythmias, sudden cardiac death, and heart failure. There are few data on the impact of...

journal_title：European journal of heart failure

authors： van Rijsingen IA,Nannenberg EA,Arbustini E,Elliott PM,Mogensen J,Hermans-van Ast JF,van der Kooi AJ,van Tintelen JP,van den Berg MP,Grasso M,Serio A,Jenkins S,Rowland C,Richard P,Wilde AA,Perrot A,Pankuweit S,Zwinderman

更新日期：2013-04-01 00:00:00

abstract：:Patients with mild-moderate chronic heart failure (CHF) often have raised levels of serum uric acid (UA). This is due, amongst other factors, to reduced UA excretion by the kidneys, which is partly explained by restriction of sodium intake and treatment with diuretics. The decline in renal function that parallels wors...

journal_title：European journal of heart failure

authors： Reyes AJ

更新日期：2005-06-01 00:00:00