当前位置： SCI文献检索 > EUROPEAN JOURNAL OF HEART FAILURE期刊下所有文献 > Clinical course after a first episode of heart failure: insights from the Framingham Heart Study.

Clinical course after a first episode of heart failure: insights from the Framingham Heart Study.

Abstract：

AIMS:We sought to describe the frequency, type and timing of clinical events, and delineate patterns in their transitions, after a first episode of heart failure (HF). METHODS AND RESULTS:In 1036 Framingham participants with new-onset HF (mean age 79 years; 53% women), we used mixture models to estimate probabilities of, and time to cardiac death, other cardiovascular disease (CVD) death, recurrent HF, cardiac events and other CVD events, accounting for age, sex, HF type (preserved vs. reduced ejection fraction), and prevalent cardiac/CVD events. The most common first events after new-onset HF were cardiac (36%), recurrent HF (28%) and death (29%). Compared with recurrent HF (referent transition state), prevalent cardiac events were associated with higher odds of fatal [odds ratio (OR) 1.90, 95% confidence interval (CI) 1.11-3.23] and non-fatal (OR 2.13, 95% CI 1.52-3.00) cardiac events; prevalent CVD increased odds of other CVD death (OR 1.90, 95% CI 1.04-3.47). Among 715 participants without a fatal initial event, there were 3337 distinct epochs (inter-event time periods), with median 3.0 epochs/participant [49% cardiac (n = 1639); 27% recurrent HF (n = 912)]. Median inter-event times varied between 12 to 285 days (recurrent HF to other CVD death and non-fatal other CVD, respectively). Prior HF, cardiac and other CVD events significantly increased odds of developing the same event-type (OR ∼ 5-7-fold), with shortened time to recurrence, indicating 'rapid cycling loops' of the same event type. HF type did not impact the nature or timing of future events. CONCLUSIONS:Comorbidities but not HF type impact clinical course of HF by influencing the type and timing of subsequent events, denoting 'natural history loops' within the overall HF population.

journal_name

Eur J Heart Fail

journal_title

European journal of heart failure

authors

Velagaleti RS,Larson MG,Enserro D,Song RJ,Vasan RS

doi

10.1002/ejhf.1918

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

1768-1776

issue

10

eissn

1388-9842

issn

1879-0844

journal_volume

22

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF HEART FAILURE文献大全
  • Utility of lung ultrasound in predicting pulmonary and cardiac pressures.

    abstract：AIMS:Quantification of linear lung ultrasound (LUS) artefacts (B-lines) represents a novel, non-invasive approach to assess pulmonary congestion. We investigated the relationship between the number of B-lines (vertical artefacts arising from the pleural line) and intracardiac pressures. METHODS AND RESULTS:Prior to sc...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1093/eurjhf/hfs144

    authors： Platz E,Lattanzi A,Agbo C,Takeuchi M,Resnic FS,Solomon SD,Desai AS

    更新日期：2012-11-01 00:00:00

  • Prevalence and prognostic significance of atrial fibrillation in outpatients with heart failure due to left ventricular systolic dysfunction.

    abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ejheart.2006.08.004

    authors： Corell P,Gustafsson F,Schou M,Markenvard J,Nielsen T,Hildebrandt P

    更新日期：2007-03-01 00:00:00

  • Effects of applying a standardised management algorithm for moderate to severe renal dysfunction in patients with chronic stable heart failure.

    abstract：BACKGROUND:No specific guidelines exist on how to manage renal dysfunction (RD) in patients with chronic heart failure (CHF). AIMS:To identify the proportion of patients with moderate to severe RD and CHF who showed an improvement in their renal function in response to a systematic management algorithm. METHODS:Stabl...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2006.10.003

    authors： de Silva R,Nikitin NP,Witte KK,Rigby AS,Loh H,Nicholson A,Bhandari S,Clark AL,Cleland JG

    更新日期：2007-04-01 00:00:00

  • Clinical significance of pulse pressure in patients with heart failure with preserved left ventricular ejection fraction.

    abstract：AIMS:Although pulse pressure (PP) is a recognized risk factor for various cardiovascular diseases, its association with cardiovascular outcomes in patients with heart failure with preserved ejection fraction (HFpEF) is uncertain. METHODS AND RESULTS:We enrolled 512 of 951 consecutive HFpEF patients admitted to the Kum...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.559

    authors： Tokitsu T,Yamamoto E,Hirata Y,Kusaka H,Fujisue K,Sueta D,Sugamura K,Sakamoto K,Tsujita K,Kaikita K,Hokimoto S,Sugiyama S,Ogawa H

    更新日期：2016-11-01 00:00:00

  • Adherence to the medical regime in patients with heart failure.

    abstract：AIMS:To assess adherence to medical treatment in patients with heart failure (HF) using a specific questionnaire and measurement of the serum concentration of digoxin. METHODS AND RESULTS:Forty patients with symptomatic HF and a clinical indication for digoxin were included in this pilot study. The assessment of adher...

    journal_title：European journal of heart failure

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1093/eurjhf/hfq015

    authors： Muzzarelli S,Brunner-La Rocca H,Pfister O,Foglia P,Moschovitis G,Mombelli G,Stricker H

    更新日期：2010-04-01 00:00:00

  • Prevalence and aetiology of heart failure in an Arab population.

    abstract：BACKGROUND:The epidemiology of heart failure in Arabia, with a population different from the West in cultural and ethnic origin, has not been studied before. AIMS:To determine the prevalence and aetiologies of symptomatic heart failure in an indigenous Arab population over a 3-year period. METHODS:All patients with h...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/s1388-9842(00)00149-5

    authors： Agarwal AK,Venugopalan P,de Bono D

    更新日期：2001-06-01 00:00:00

  • Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation.

    abstract：:The European Society of Cardiology heart failure guidelines firmly recommend regular physical activity and structured exercise training (ET), but this recommendation is still poorly implemented in daily clinical practice outside specialized centres and in the real world of heart failure clinics. In reality, exercise i...

    journal_title：European journal of heart failure

    pub_type： 共识发展会议,杂志文章

    doi：10.1093/eurjhf/hfr017

    authors： Piepoli MF,Conraads V,Corrà U,Dickstein K,Francis DP,Jaarsma T,McMurray J,Pieske B,Piotrowicz E,Schmid JP,Anker SD,Solal AC,Filippatos GS,Hoes AW,Gielen S,Giannuzzi P,Ponikowski PP

    更新日期：2011-04-01 00:00:00

  • Reduced in vivo skeletal muscle oxygen consumption in patients with chronic heart failure--a study using Near Infrared Spectrophotometry (NIRS).

    abstract：AIM:We used Near Infrared Spectrophotometry (NIRS) during arterial occlusion to measure resting skeletal muscle oxygen consumption in chronic heart failure (CHF) patients and in age-matched healthy volunteers (HVs). METHODS:Fifteen CHF patients (ten males) and eleven HVs (six males) had echocardiographic evaluation fo...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2008.05.009

    authors： Abozguia K,Phan TT,Shivu GN,Maher AR,Ahmed I,Wagenmakers A,Frenneaux MP

    更新日期：2008-07-01 00:00:00

  • The effect of aspirin on the ventilatory response to exercise in chronic heart failure.

    abstract：INTRODUCTION:Patients with chronic heart failure (CHF) experience breathlessness and fatigue on exercise. One of the abnormalities seen on maximal exercise testing is an increased ventilatory response to exercise (VE/VCO(2) slope). The cause of this is unknown, but is likely to be due to a combination of interacting pe...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2003.11.008

    authors： Witte KK,Clark AL

    更新日期：2004-10-01 00:00:00

  • Dietary sodium modulation of aldosterone activation and renal function during the progression of experimental heart failure.

    abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.212

    authors： Miller WL,Borgeson DD,Grantham JA,Luchner A,Redfield MM,Burnett JC Jr

    更新日期：2015-02-01 00:00:00

  • Negative inotropic effects of recombinant interleukin 2 in patients without left ventricular dysfunction.

    abstract：UNLABELLED:Experimental data have shown that rIL2 has negative inotropic properties. This has not been investigated in humans with normal left ventricular function. Seventeen consecutive renal cell carcinoma patients who received rIL2 therapy because of dissemination were analyzed before and after treatment with a low ...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/s1388-9842(00)00073-8

    authors： Tio RA,Nieken J,de Vries EG,Pfeiffer C,de Jongste MJ,Pieper E,Moshage H,Limburg PC,Mulder NH

    更新日期：2000-06-01 00:00:00

  • Tobacco smoke-induced left ventricular remodelling is not associated with metalloproteinase-2 or -9 activation.

    abstract：AIM:To investigate the role of MMP-2 and MMP-9 in cardiac remodelling induced by tobacco smoke exposure in rats. METHODS:Rats were allocated into two groups: C (n=9): control animals; ETS (n=9): exposed to tobacco smoke. After 4months, the animals underwent echocardiography, morphometric study and determination of MMP...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2007.09.004

    authors： Castardeli E,Duarte DR,Minicucci MF,Azevedo PS,Matsubara BB,Matsubara LS,Campana AO,Paiva SA,Zornoff LA

    更新日期：2007-11-01 00:00:00

  • Brain magnetic resonance imaging abnormalities in patients with heart failure.

    abstract：BACKGROUND:Although heart failure (HF) is a common cardiovascular disorder, to date little research has been conducted into possible associations between HF and structural abnormalities of the brain. AIMS:To determine the frequency and pattern of magnetic resonance imaging (MRI) abnormalities in outpatients with chron...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2007.07.006

    authors： Vogels RL,van der Flier WM,van Harten B,Gouw AA,Scheltens P,Schroeder-Tanka JM,Weinstein HC

    更新日期：2007-10-01 00:00:00

  • Correlation between serial measurements of N-terminal pro brain natriuretic peptide and ambulatory cardiac filling pressures in outpatients with chronic heart failure.

    abstract：BACKGROUND:Serial measurements of N-terminal pro brain natriuretic peptide (NT-proBNP) have been suggested for the management of outpatients with chronic heart failure (CHF). The relationship between NT-proBNP plasma levels and central haemodynamic parameters in this setting is not known. METHODS:In 19 outpatients wit...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2006.03.002

    authors： Braunschweig F,Fahrleitner-Pammer A,Mangiavacchi M,Ghio S,Fotuhi P,Hoppe UC,Linde C

    更新日期：2006-12-01 00:00:00

  • Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens.

    abstract：AIMS:To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). METHODS AND RESULTS:A 5-day open-label run-in (sacubitril/valsartan 50 mg twice daily) preceded an 11-week, dou...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1002/ejhf.548

    authors： Senni M,McMurray JJ,Wachter R,McIntyre HF,Reyes A,Majercak I,Andreka P,Shehova-Yankova N,Anand I,Yilmaz MB,Gogia H,Martinez-Selles M,Fischer S,Zilahi Z,Cosmi F,Gelev V,Galve E,Gómez-Doblas JJ,Nociar J,Radomska M,S

    更新日期：2016-09-01 00:00:00

  • Comparison of myocardial deformation and velocity dyssynchrony for identification of responders to cardiac resynchronization therapy.

    abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,多中心研究

    doi：10.1093/eurjhf/hfp032

    authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

    更新日期：2009-04-01 00:00:00

  • Correlation of flow mediated dilation with inflammatory markers in patients with impaired cardiac function. Beneficial effects of inhibition of ACE.

    abstract：:Impaired cardiac function is frequently accompanied by peripheral vascular dysfunction and a pro-inflammatory condition, which may be associated with elevated levels of angiotensin II. We hypothesized that the magnitude of flow mediated dilatation (FMD) of the brachial artery of post myocardial infarction patients wil...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ejheart.2005.10.011

    authors： Kovacs I,Toth J,Tarjan J,Koller A

    更新日期：2006-08-01 00:00:00

  • Heart failure with preserved ejection fraction: the impact of stricter definitions.

    abstract：AIMS:To determine the impact of internationally recognized criteria for the diagnosis of heart failure with preserved ejection fraction (HF-PEF) on the feasibility of recruitment into a HF-PEF trial. METHODS AND RESULTS:We reviewed the medical records of 5883 consecutive patients admitted with heart failure across eig...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.106

    authors： Patel HC,Hayward C,di Mario C,Cowie MR,Lyon AR,Rosen SD

    更新日期：2014-07-01 00:00:00

  • Progressive left ventricular hypertrophy after withdrawal of long-term ACE inhibition following experimental myocardial infarction.

    abstract：BACKGROUND:Although discontinuation of chronic ACE inhibitor (ACEi) therapy after myocardial infarction (MI) is common in clinical practice, some clinical studies reported an increased incidence of ischemia-related events after withdrawal. To further address this issue, we assessed hemodynamic, neurohormonal and vascul...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2005.04.014

    authors： Westendorp B,Schoemaker RG,Buikema H,Boomsma F,van Veldhuisen DJ,van Gilst WH

    更新日期：2006-03-01 00:00:00

  • A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry.

    abstract：AIMS:Clinical presentation of takotsubo syndrome (TTS) mimics acute coronary syndrome (ACS) and does not allow differentiation. We aimed to develop a clinical score to estimate the probability of TTS and to distinguish TTS from ACS in the acute stage. METHODS AND RESULTS:Patients with TTS were recruited from the Inter...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1002/ejhf.683

    authors： Ghadri JR,Cammann VL,Jurisic S,Seifert B,Napp LC,Diekmann J,Bataiosu DR,D'Ascenzo F,Ding KJ,Sarcon A,Kazemian E,Birri T,Ruschitzka F,Lüscher TF,Templin C,InterTAK co-investigators.

    更新日期：2017-08-01 00:00:00

  • Relation of atrial natriuretic peptides to left ventricular systolic and diastolic function in heart failure.

    abstract：BACKGROUND:Plasma concentrations of atrial natriuretic peptides are correlated with atrial pressures, as are left ventricular ejection fraction and left ventricular filling abnormalities. AIMS:This study investigated the relation of atrial natriuretic peptides to both left ventricular systolic and diastolic function i...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/s1388-9842(98)00005-1

    authors： Wijbenga AA,Balk AH,Jonkman FA,Boomsma F,Simoons ML,Man in t Veld AJ

    更新日期：1999-03-01 00:00:00

  • Efficacy of antithrombotic therapy in chronic heart failure: the HELAS study.

    abstract：BACKGROUND:It is not clear if long-term antithrombotic treatment has a beneficial effect on the incidence of thromboembolism in chronic heart failure (CHF). The HELAS study (Heart failure Long-term Antithrombotic Study) is a multicentre, randomised, double-blind, placebo-controlled trial to evaluate antithrombotic trea...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.ejheart.2006.02.012

    authors： Cokkinos DV,Haralabopoulos GC,Kostis JB,Toutouzas PK,HELAS investigators.

    更新日期：2006-06-01 00:00:00

  • Right ventricular dysfunction in heart failure with preserved ejection fraction: a systematic review and meta-analysis.

    abstract：AIMS:Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and prognostic value of RV dysfunction in HFpEF have been widely but variably reported. We therefore conducted a systematic review and meta-analys...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,meta分析,评审

    doi：10.1002/ejhf.630

    authors： Gorter TM,Hoendermis ES,van Veldhuisen DJ,Voors AA,Lam CS,Geelhoed B,Willems TP,van Melle JP

    更新日期：2016-12-01 00:00:00

  • Improvement but no cure of left ventricular systolic dysfunction in treated heart failure patients.

    abstract：BACKGROUND:Recent advances in pharmacological and pacemaker-based treatments for heart failure (HF) have brought about significant improvements in left ventricular function. AIMS:To identify the proportion of treated systolic HF patients in whom left ventricular systolic function improves and/or returns to normal. ME...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2007.10.001

    authors： Murphy NF,O'Loughlin C,Ledwidge M,McCaffrey D,McDonald K

    更新日期：2007-12-01 00:00:00

  • A rationale for early extracorporeal membrane oxygenation in patients with postinfarction ventricular septal rupture complicated by cardiogenic shock.

    abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.852

    authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

    更新日期：2017-05-01 00:00:00

  • Which patients with heart failure should receive specialist palliative care?

    abstract：AIMS:We investigated which patients with heart failure (HF) should receive specialist palliative care (SPC) by first creating a definition of need for SPC in patients hospitalised with HF using patient-reported outcome measures (PROMs) and then testing this definition using the outcome of days alive and out of hospital...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.1240

    authors： Campbell RT,Petrie MC,Jackson CE,Jhund PS,Wright A,Gardner RS,Sonecki P,Pozzi A,McSkimming P,McConnachie A,Finlay F,Davidson P,Denvir MA,Johnson MJ,Hogg KJ,McMurray JJV

    更新日期：2018-09-01 00:00:00

  • Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunction.

    abstract：BACKGROUND:Renal failure in heart failure is related to decreased cardiac output. However, little is known about its association with venous congestion. AIMS:To investigate the relationship between venous congestion and glomerular filtration rate (GFR) in patients with cardiac dysfunction. METHODS AND RESULTS:Right a...

    journal_title：European journal of heart failure

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ejheart.2007.05.010

    authors： Damman K,Navis G,Smilde TD,Voors AA,van der Bij W,van Veldhuisen DJ,Hillege HL

    更新日期：2007-09-01 00:00:00

  • Pharmacological treatment in patients with heart failure: patients knowledge and occurrence of polypharmacy, alternative medicine and immunizations.

    abstract：AIMS:To evaluate in patients with heart failure (HF) due to systolic dysfunction the occurrence of polypharmacy, alternative medicine, immunization against influenza, and patients' knowledge about their medication. METHODS AND RESULTS:Sixty-five patients, 49 men, mean age 60.5+/-12.0 years answered a confidential ques...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1016/j.ejheart.2003.09.009

    authors： Martínez-Sellés M,García Robles JA,Muñoz R,Serrano JA,Frades E,Domínguez Muñoa M,Almendral J

    更新日期：2004-03-01 00:00:00

  • Insights into the importance of the electrocardiogram in patients with acute heart failure.

    abstract：BACKGROUND:Patients presenting to the emergency department (ED) with acute heart failure (AHF) are at an increased risk of morbidity and mortality. The electrocardiogram (ECG) is a routine investigation in patients with AHF used to identify potential causes and/or complications. It is unclear whether 12-lead ECG charac...

    journal_title：European journal of heart failure

    pub_type： 杂志文章

    doi：10.1002/ejhf.561

    authors： Gouda P,Brown P,Rowe BH,McAlister FA,Ezekowitz JA

    更新日期：2016-08-01 00:00:00

  • The effect of physical training in chronic heart failure.

    abstract：BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...

    journal_title：European journal of heart failure

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ejheart.2005.05.002

    authors： Jónsdóttir S,Andersen KK,Sigurosson AF,Sigurosson SB

    更新日期：2006-01-01 00:00:00