COMBAT--conventional versus multisite pacing for bradyarrhythmia therapy: rationale of a prospective randomized multicenter study.

abstract：BACKGROUND:The role of the right ventricle has been relatively neglected proportionate to its importance. We sought to evaluate the impact of right ventricular (RV) and NT-proBNP on the outcome of patients with heart failure (HF) and functional mitral regurgitation (MR). METHODS AND PATIENTS:Outpatients with left vent...

journal_title：European journal of heart failure

authors： Dini FL,Fontanive P,Panicucci E,Andreini D,Chella P,De Tommasi SM

更新日期：2008-06-01 00:00:00

abstract：AIMS:The primary objective of this systematic review was to estimate the prevalence and temporal changes in chronic comorbid conditions reported in heart failure (HF) clinical trials. METHODS AND RESULTS:We searched MEDLINE for HF trials enrolling more than 400 patients published between 2001 and 2016.Trials were divi...

journal_title：European journal of heart failure

authors： Khan MS,Samman Tahhan A,Vaduganathan M,Greene SJ,Alrohaibani A,Anker SD,Vardeny O,Fonarow GC,Butler J

更新日期：2020-06-01 00:00:00

abstract：AIMS:A recent study suggested that no single echocardiographic index of cardiac dyssynchrony can reliably identify candidates for cardiac resynchronization therapy (CRT). We examined the value of three simple echocardiographic indices for predicting the 6-month clinical and echocardiographic responses to CRT. METHODS ...

journal_title：European journal of heart failure

authors： Bordachar P,Lafitte S,Réant P,Reuter S,Clementy J,Mletzko RU,Siegel RM,Goscinska-Bis K,Bowes R,Morgan J,Bénard S,Leclercq C

更新日期：2010-06-01 00:00:00

abstract：AIMS:Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced...

journal_title：European journal of heart failure

authors： Dickinson BA,Semus HM,Montgomery RL,Stack C,Latimer PA,Lewton SM,Lynch JM,Hullinger TG,Seto AG,van Rooij E

更新日期：2013-06-01 00:00:00

abstract：:Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney function was primarily assessed by serum creatinine and the calculation of estimated glomerular filtration rate. An increase in serum creatinine, also termed wo...

journal_title：European journal of heart failure

authors： Mullens W,Damman K,Testani JM,Martens P,Mueller C,Lassus J,Tang WHW,Skouri H,Verbrugge FH,Orso F,Hill L,Ural D,Lainscak M,Rossignol P,Metra M,Mebazaa A,Seferovic P,Ruschitzka F,Coats A

更新日期：2020-04-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：:Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients...

journal_title：European journal of heart failure

authors： Kamperidis V,Delgado V,van Mieghem NM,Kappetein AP,Leon MB,Bax JJ

更新日期：2016-05-01 00:00:00

abstract：AIMS:Acute heart failure (AHF) has a poor prognosis. We evaluated 3- and 12-month mortality in different clinical classes of AHF patients from 30 European countries who were included in the EuroHeart Failure Survey (EHFS) II. METHODS AND RESULTS:Follow-up data were available for 2981 AHF patients, of these 62% had a h...

journal_title：European journal of heart failure

authors： Harjola VP,Follath F,Nieminen MS,Brutsaert D,Dickstein K,Drexler H,Hochadel M,Komajda M,Lopez-Sendon JL,Ponikowski P,Tavazzi L

更新日期：2010-03-01 00:00:00

abstract：AIMS:As pulmonary arterial hypertension (PAH) is associated with significant morbidity and mortality, particularly among patients with right ventricular (RV) dysfunction, we aimed to determine the impact of therapy to reduce pulmonary vascular resistance (PVR) on RV and LV deformation in PAH. METHODS AND RESULTS:Right...

journal_title：European journal of heart failure

authors： Querejeta Roca G,Campbell P,Claggett B,Vazir A,Quinn D,Solomon SD,Shah AM

更新日期：2015-01-01 00:00:00

abstract：AIMS:The MITRA-FR trial showed that among symptomatic patients with severe secondary mitral regurgitation, percutaneous repair did not reduce the risk of death or hospitalization for heart failure at 12 months compared with guideline-directed medical treatment alone. We report the 24-month outcome from this trial. MET...

journal_title：European journal of heart failure

authors： Iung B,Armoiry X,Vahanian A,Boutitie F,Mewton N,Trochu JN,Lefèvre T,Messika-Zeitoun D,Guerin P,Cormier B,Brochet E,Thibault H,Himbert D,Thivolet S,Leurent G,Bonnet G,Donal E,Piriou N,Piot C,Habib G,Rouleau F,Car

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Suppression of the renin-angiotensin-aldosterone system (RAAS) is therapeutically valuable in chronic heart failure (CHF). RAAS inhibition can be achieved in a number of ways though an orally active renin inhibitor (RI) has never been studied before. We describe the neurohumoral effects of an RI. METHODS AN...

journal_title：European journal of heart failure

authors： Seed A,Gardner R,McMurray J,Hillier C,Murdoch D,MacFadyen R,Bobillier A,Mann J,McDonagh T

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Although discontinuation of chronic ACE inhibitor (ACEi) therapy after myocardial infarction (MI) is common in clinical practice, some clinical studies reported an increased incidence of ischemia-related events after withdrawal. To further address this issue, we assessed hemodynamic, neurohormonal and vascul...

journal_title：European journal of heart failure

authors： Westendorp B,Schoemaker RG,Buikema H,Boomsma F,van Veldhuisen DJ,van Gilst WH

更新日期：2006-03-01 00:00:00

abstract：AIMS:Pulmonary hypertension (PH) due to systolic left ventricular dysfunction (PH-sLVD) frequently complicates heart failure (HF), and greatly worsens the prognosis of patients with sLVD, but as yet has no approved treatment. The LEPHT study aims to characterize the haemodynamic profile, safety, tolerability, and pharm...

journal_title：European journal of heart failure

authors： Ghio S,Bonderman D,Felix SB,Ghofrani HA,Michelakis ED,Mitrovic V,Oudiz RJ,Frey R,Roessig L,Semigran MJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:We describe the baseline characteristics of subjects randomised in the largest placebo-controlled, morbidity-mortality trial to date in patients with heart failure and preserved ejection fraction - the irbesartan in heart failure with preserved systolic function trial (I-PRESERVE). METHODS AND RESULTS:4133 ...

journal_title：European journal of heart failure

authors： McMurray JJ,Carson PE,Komajda M,McKelvie R,Zile MR,Ptaszynska A,Staiger C,Donovan JM,Massie BM

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:There are established differences in cardiovascular disease in different racial groups. Worldwide, the literature regarding the clinical epidemiology of congestive heart failure (CHF) in non-white populations is scarce. OBJECTIVES:To document the prevalence of CHF in the multiracial population of Malaysia, ...

journal_title：European journal of heart failure

authors： Chong AY,Rajaratnam R,Hussein NR,Lip GY

更新日期：2003-08-01 00:00:00

abstract：AIMS:Severe heart failure (HF) is often associated with cachexia that reverses post-heart transplantation (HTx) with frequent development of obesity. Ghrelin is a novel appetite-stimulating hormone. The aim was to determine the role of ghrelin in regulating appetite, food intake, and body composition in HF and post-HTx...

journal_title：European journal of heart failure

authors： Lund LH,Williams JJ,Freda P,LaManca JJ,LeJemtel TH,Mancini DM

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Plasma levels of N-terminal pro-brain natriuretic peptide (NT-pro BNP) are increased in patients with chronic heart failure (CHF). Beta-blockers (BB) may influence these levels but it is unclear whether changes in NT-pro BNP reflect concomitant changes in prognosis. OBJECTIVES:To assess the prognostic impor...

journal_title：European journal of heart failure

authors： Olsson LG,Swedberg K,Cleland JG,Spark PA,Komajda M,Metra M,Torp-Pedersen C,Remme WJ,Scherhag A,Poole-Wilson P,COMET Investigators.

更新日期：2007-08-01 00:00:00

abstract：AIMS:Supervised exercise can benefit selected patients with heart failure, however the effectiveness of home-based exercise remains uncertain. We aimed to assess the effectiveness of a home-based exercise programme in addition to specialist heart failure nurse care. METHODS AND RESULTS:This was a randomized controlled...

journal_title：European journal of heart failure

authors： Jolly K,Taylor RS,Lip GY,Davies M,Davis R,Mant J,Singh S,Greenfield S,Ingram J,Stubley J,Bryan S,Stevens A

更新日期：2009-02-01 00:00:00

abstract：AIMS:Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support stabilizes patients with cardiogenic shock. Despite improved oxygenation and peripheral circulation, LV unloading may be impeded due to the increased afterload, resulting in a failing static left ventricle and in high mortality. METHODS AND RESUL...

journal_title：European journal of heart failure

authors： Pappalardo F,Schulte C,Pieri M,Schrage B,Contri R,Soeffker G,Greco T,Lembo R,Müllerleile K,Colombo A,Sydow K,De Bonis M,Wagner F,Reichenspurner H,Blankenberg S,Zangrillo A,Westermann D

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Regional presynaptic sympathetic innervation varies considerably in the cardiomyopathic human heart, as shown in previous studies in vivo and in vitro. The goal of the present study was to correlate markers of presynaptic sympathetic innervation with local measurement of the postsynaptic beta-adrenergic syst...

journal_title：European journal of heart failure

authors： Ungerer M,Weig HJ,Kübert S,Overbeck M,Bengel F,Schömig A,Schwaiger M

更新日期：2000-03-01 00:00:00

abstract：AIMS:Growth differentiation factor-15 (GDF-15) is associated with adverse prognosis in cardiovascular (CV) and non-CV diseases. We evaluated the association of GDF-15 with CV and non-CV outcomes in the PARADIGM-HF trial. METHODS AND RESULTS:In 1935 patients with heart failure and reduced ejection fraction (HFrEF) in P...

journal_title：European journal of heart failure

authors： Bouabdallaoui N,Claggett B,Zile MR,McMurray JJV,O'Meara E,Packer M,Prescott MF,Swedberg K,Solomon SD,Rouleau JL,PARADIGM-HF Investigators and Committees.

更新日期：2018-12-01 00:00:00

abstract：AIM:The exercise Doppler echocardiographic stress test can be of interest in the management of asymptomatic patients with primary mitral regurgitation (MR). The resting brain natriuretic peptide (BNP) level is a good surrogate marker of the consequences of MR and is a powerful predictor of outcome. The incremental prog...

journal_title：European journal of heart failure

authors： Magne J,Mahjoub H,Pibarot P,Pirlet C,Pierard LA,Lancellotti P

更新日期：2012-11-01 00:00:00

abstract：:Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally...

journal_title：European journal of heart failure

authors： Hawkins NM,Petrie MC,Jhund PS,Chalmers GW,Dunn FG,McMurray JJ

更新日期：2009-02-01 00:00:00

abstract：AIMS:Women with heart failure (HF) are under-represented in individual randomized clinical trials (RCTs). Little is known about sex-specific treatment effects in HF medications. We evaluated sex differences in the response to mineralocorticoid receptor antagonists (MRAs) in major HF MRA trials, including a broad spectr...

journal_title：European journal of heart failure

authors： Rossello X,Ferreira JP,Pocock SJ,McMurray JJV,Solomon SD,Lam CSP,Girerd N,Pitt B,Rossignol P,Zannad F

更新日期：2020-05-01 00:00:00

abstract：:Although no universal definition exists, decompensated heart failure may be regarded as either a worsening of chronic heart failure or new-onset heart failure precipitated by an acute incident. Haemodynamic management of patients hospitalised with decompensated heart failure may include the administration of diuretics...

journal_title：European journal of heart failure

authors： Greenberg B,Borghi C,Perrone S

更新日期：2003-01-01 00:00:00

abstract：:Cardiac contractility modulating (CCM) signals delivered by the OPTIMIZER System are being investigated as a treatment for medically refractory heart failure. Previous chronic studies of CCM have excluded patients with prolonged QRS and a cardiac resynchronization therapy (CRT) device. However, symptoms persist in mor...

journal_title：European journal of heart failure

authors： Butter C,Meyhöfer J,Seifert M,Neuss M,Minden HH

更新日期：2007-09-01 00:00:00

abstract：AIMS:Exercise-derived parameters, specifically peak exercise oxygen uptake (peak VO2 ) and minute ventilation/carbon dioxide relationship slope (VE/VCO2 slope), have a pivotal prognostic value in heart failure (HF). It is unknown how the prognostic threshold of peak VO2 and VE/VCO2 slope has changed over the last 20 ye...

journal_title：European journal of heart failure

authors： Paolillo S,Veglia F,Salvioni E,Corrà U,Piepoli M,Lagioia R,Limongelli G,Sinagra G,Cattadori G,Scardovi AB,Metra M,Senni M,Bonomi A,Scrutinio D,Raimondo R,Emdin M,Magrì D,Parati G,Re F,Cicoira M,Minà C,Correale M

更新日期：2019-02-01 00:00:00

abstract：AIMS:Right ventricular (RV) dysfunction has been associated with a worse outcome in heart failure patients undergoing CRT. However, evidence on the RV response to CRT is controversial and there are no data regarding the early effects of CRT on RV function (RVF). We sought to investigate whether a CRT device favourably ...

journal_title：European journal of heart failure

authors： Stolfo D,Tonet E,Merlo M,Barbati G,Gigli M,Pinamonti B,Ramani F,Zecchin M,Sinagra G

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Most patients suspected of having heart failure (HF) will get a 12-lead electrocardiogram (ECG) but its utility for excluding HF or assisting in its management has rarely been investigated. METHODS:The EuroHeart Failure survey identified 11,327 patients hospitalised with a suspected diagnosis of HF from 115...

journal_title：European journal of heart failure

authors： Khan NK,Goode KM,Cleland JG,Rigby AS,Freemantle N,Eastaugh J,Clark AL,de Silva R,Calvert MJ,Swedberg K,Komajda M,Mareev V,Follath F,EuroHeart Failure Survey Investigators.

更新日期：2007-05-01 00:00:00

abstract：AIMS:Post-discharge morbidity and mortality for acute heart failure (AHF) patients remains high. Although the adverse effects of neurohormonal activation are well known in chronic HF, the prognostic significance of serum aldosterone in patients hospitalized for AHF has not been well studied. METHODS AND RESULTS:A seco...

journal_title：European journal of heart failure

authors： Girerd N,Pang PS,Swedberg K,Fought A,Kwasny MJ,Subacius H,Konstam MA,Maggioni A,Gheorghiade M,Zannad F,EVEREST investigators.

更新日期：2013-11-01 00:00:00