Plasma microRNAs serve as biomarkers of therapeutic efficacy and disease progression in hypertension-induced heart failure.

abstract：:Nitric oxide (NO) appears to play a role in modulating cardiac function in both health and disease. Early studies in isolated rodent cardiac myocytes demonstrated a depressant effect of NO supplied by NO donors (exogenous) as well as NO generated within myocytes (endogenous). There is increasing evidence for a functio...

journal_title：European journal of heart failure

authors： Sarkar D,Vallance P,Harding SE

更新日期：2001-10-01 00:00:00

abstract：AIMS:Heart failure (HF) patients with a mid-range ejection fraction (HFmrEF) are not well characterized. Accordingly, we examined the epidemiology, pathophysiology and clinical outcomes of HF patients with a left ventricular ejection fraction (LVEF) of 40-50%. METHODS AND RESULTS:We identified 168 patients with an LVE...

journal_title：European journal of heart failure

authors： Rastogi A,Novak E,Platts AE,Mann DL

更新日期：2017-12-01 00:00:00

abstract：UNLABELLED:Aim Frequent ventricular premature contractions (VPCs) may cause haemodynamic deterioration and reversible left ventricular (LV) dysfunction. We aimed to clarify this mechanism. METHODS AND RESULTS:The haemodynamics, echocardiographic parameters, and plasma brain natriuretic peptide (BNP) level were assesse...

journal_title：European journal of heart failure

authors： Kuroki K,Tada H,Seo Y,Ishizu T,Igawa M,Yamasaki H,Igarashi M,Machino T,Naruse Y,Sekiguchi Y,Murakoshi N,Aonuma K

更新日期：2012-10-01 00:00:00

abstract：:The incidence and prevalence of cardiovascular disease increases progressively with advancing age. Cardiovascular disease is a major cause of morbidity and mortality in Western Countries. In the near future, as the population ages, it is expected that the population prevalence of cardiovascular disease will increase d...

journal_title：European journal of heart failure

authors： Wong LS,de Boer RA,Samani NJ,van Veldhuisen DJ,van der Harst P

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Regional presynaptic sympathetic innervation varies considerably in the cardiomyopathic human heart, as shown in previous studies in vivo and in vitro. The goal of the present study was to correlate markers of presynaptic sympathetic innervation with local measurement of the postsynaptic beta-adrenergic syst...

journal_title：European journal of heart failure

authors： Ungerer M,Weig HJ,Kübert S,Overbeck M,Bengel F,Schömig A,Schwaiger M

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The diagnosis of heart failure is an important clinical problem and yet reported diagnostic accuracy in primary care is less than 50%. We established a Rapid Access Heart Failure Clinic (RAHFC) in a district general hospital serving a population of 292,000 in SE London, UK, to diagnose and manage ne...

journal_title：European journal of heart failure

authors： Fox KF,Cowie MR,Wood DA,Coats AJ,Poole-Wilson PA,Sutton GC

更新日期：2000-12-01 00:00:00

abstract：AIMS:The identification of valuable markers of sudden cardiac death (SCD) in patients with established HF remains a challenge. We sought to assess the value of clinical, echocardiographic and biochemical variables to predict SCD in a consecutive cohort of patients with heart failure (HF) due to systolic dysfunction. M...

journal_title：European journal of heart failure

authors： Bayes-Genis A,Vazquez R,Puig T,Fernandez-Palomeque C,Fabregat J,Bardají A,Pascual-Figal D,Ordoñez-Llanos J,Valdes M,Gabarrús A,Pavon R,Pastor L,Gonzalez Juanatey JR,Almendral J,Fiol M,Nieto V,Macaya C,Cinca J,Bayes de

更新日期：2007-08-01 00:00:00

abstract：AIMS:To investigate temporal trends in the risk of heart failure (HF) complicating acute myocardial infarction (AMI) and to determine whether these trends differ by gender or age. METHODS AND RESULTS:The national Swedish hospital discharge and death registries from 1993 to 2004 were used to calculate age- and gender-s...

journal_title：European journal of heart failure

authors： Shafazand M,Rosengren A,Lappas G,Swedberg K,Schaufelberger M

更新日期：2011-02-01 00:00:00

abstract：AIM:We used Near Infrared Spectrophotometry (NIRS) during arterial occlusion to measure resting skeletal muscle oxygen consumption in chronic heart failure (CHF) patients and in age-matched healthy volunteers (HVs). METHODS:Fifteen CHF patients (ten males) and eleven HVs (six males) had echocardiographic evaluation fo...

journal_title：European journal of heart failure

authors： Abozguia K,Phan TT,Shivu GN,Maher AR,Ahmed I,Wagenmakers A,Frenneaux MP

更新日期：2008-07-01 00:00:00

abstract：:Patients with mild-moderate chronic heart failure (CHF) often have raised levels of serum uric acid (UA). This is due, amongst other factors, to reduced UA excretion by the kidneys, which is partly explained by restriction of sodium intake and treatment with diuretics. The decline in renal function that parallels wors...

journal_title：European journal of heart failure

authors： Reyes AJ

更新日期：2005-06-01 00:00:00

abstract：AIMS:In this randomized, double-blind clinical study, we investigated the relationship between autoantibodies against cardiac troponin I (cTnI) and disease severity in elderly congestive heart failure (CHF) patients before and after titration of beta-blocker therapy. METHODS AND RESULTS:Anti-cTnI, cTnI, and N-terminal...

journal_title：European journal of heart failure

authors： Düngen HD,Platzeck M,Vollert J,Searle J,Müller C,Reiche J,Mehrhof F,Müller R,Möckel M

更新日期：2010-07-01 00:00:00

abstract：AIMS:Loop diuretics are essential for the treatment of chronic heart failure (CHF) but short-acting diuretics are reported to induce sympathetic nervous system (SNS) activation. This study was performed to compare therapeutic effects of two loop diuretics, long-acting azosemide and short-acting furosemide, using (123)I...

journal_title：European journal of heart failure

authors： Hisatake S,Nanjo S,Fujimoto S,Yamashina S,Yuzawa H,Namiki A,Nakano H,Yamazaki J

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Infused C-type natriuretic peptide (CNP) was recently found to play a cardioprotective role in preventing myocardial ischaemia/reperfusion (I/R) injury and improving cardiac remodelling after myocardial infarction (MI) in rats. Our study aimed to investigate the effect of cardiomyocyte-specific CNP over-expre...

journal_title：European journal of heart failure

authors： Wang Y,de Waard MC,Sterner-Kock A,Stepan H,Schultheiss HP,Duncker DJ,Walther T

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Echocardiography with Doppler examination of the aortic valve provides a very accurate assessment of the transvalvular gradient and is used to monitor progression of aortic stenosis (AS). Plasma brain natriuretic peptide (BNP) has been shown to correlate with end-systolic wall stress in patients with AS. AI...

journal_title：European journal of heart failure

authors： Talwar S,Downie PF,Squire IB,Davies JE,Barnett DB,Ng LL

更新日期：2001-01-01 00:00:00

abstract：AIMS:Structural abnormalities causing cardiac deterioration in hypertensive heart disease (HHD) are poorly understood. The aim of the study was to evaluate left ventricular (LV) myocardial changes in patients with HHD and cardiac failure. METHODS AND RESULTS:Among 1229 patients undergoing an LV or biventricular endomy...

journal_title：European journal of heart failure

authors： Frustaci A,Francone M,Petrosillo N,Chimenti C

更新日期：2013-03-01 00:00:00

abstract：AIMS:The most recent European guidelines have proposed new definitions of pulmonary hypertension (PH) in left heart disease, to better approach the characteristics required to reflect the presence of pulmonary vascular disease. The purpose of this study was to assess whether different haemodynamic definitions of post-c...

journal_title：European journal of heart failure

authors： Ghio S,Crimi G,Temporelli PL,Traversi E,La Rovere MT,Cannito A,Vizza D,Scelsi L,Raineri C,Guazzi M,Oltrona Visconti L

更新日期：2018-04-01 00:00:00

abstract：AIMS:The aim of this review is to assess the effects of exercise training on the symptoms of depression in heart failure (HF) patients. METHODS AND RESULTS:Randomized controlled trials of exercise training in patients with HF and symptoms of depression were identified. The depression data were pooled using meta-analys...

journal_title：European journal of heart failure

authors： Tu RH,Zeng ZY,Zhong GQ,Wu WF,Lu YJ,Bo ZD,He Y,Huang WQ,Yao LM

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The incidence of ventricular tachyarrhythmias in ICD patients with cardiac resynchronisation therapy (CRT-D) is not well studied. AIM:To analyse event free survival in CRT-D patients with a primary or a secondary prophylactic ICD indication. METHODS:Prospective, single centre. Eighty-six patients, 44% with...

journal_title：European journal of heart failure

authors： Theuns DA,Thornton AS,Klootwijk AP,Scholten MF,Vantrimpont PJ,Balk AH,Jordaens LJ

更新日期：2005-10-01 00:00:00

abstract：AIMS:The left ventricular phenotype of idiopathic dilated cardiomyopathy (DCM) can appear similar in paediatric and adult patients. However, the aetiology of paediatric DCM is usually idiopathic, and often leads an aggressive clinical course. A structural underpinning of DCM is extracellular matrix changes, which are d...

journal_title：European journal of heart failure

authors： Hsia TY,Ringewald JM,Stroud RE,Forbus GA,Bradley SM,Chung WK,Spinale FG

更新日期：2011-03-01 00:00:00

abstract：AIMS:Heart failure (HF) with normal or preserved left ventricular (LV) ejection fraction (HFPEF) has been reported to be associated with similar outcome as HF with reduced EF (HFREF) in registry-based and epidemiological analyses, but many of these studies excluded patients who did not have EF measurements. Conversely,...

journal_title：European journal of heart failure

authors： Somaratne JB,Berry C,McMurray JJ,Poppe KK,Doughty RN,Whalley GA

更新日期：2009-09-01 00:00:00

abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

journal_title：European journal of heart failure

authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Plasma levels of N-terminal pro-brain natriuretic peptide (NT-pro BNP) are increased in patients with chronic heart failure (CHF). Beta-blockers (BB) may influence these levels but it is unclear whether changes in NT-pro BNP reflect concomitant changes in prognosis. OBJECTIVES:To assess the prognostic impor...

journal_title：European journal of heart failure

authors： Olsson LG,Swedberg K,Cleland JG,Spark PA,Komajda M,Metra M,Torp-Pedersen C,Remme WJ,Scherhag A,Poole-Wilson P,COMET Investigators.

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The adipocyte-specific cytokine adiponectin, has cardioprotective effects, correlates with endogenous cardiac natriuretic peptides and adipocyte has guanylyl cyclase-A receptors of natriuretic peptides. AIMS:To evaluate the effect of carperitide (atrial natriuretic peptide; ANP) on plasma adiponectin in pat...

journal_title：European journal of heart failure

authors： Tanaka T,Tsutamoto T,Sakai H,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2008-04-01 00:00:00

abstract：AIMS:Patients with intestinal malabsorption may develop cardiac dysfunction the origin of which is often unclear. We sought to investigate the pathogenesis of dilated cardiomyopathy in human malabsorption. METHODS AND RESULTS:Eighteen patients with intestinal bypass as treatment for severe obesity and cardiomyopathy u...

journal_title：European journal of heart failure

authors： Frustaci A,Sabbioni E,Fortaner S,Farina M,del Torchio R,Tafani M,Morgante E,Ciriolo MR,Russo MA,Chimenti C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:EMPEROR-Preserved is an ongoing trial evaluating the effect of empagliflozin in patients with heart failure with preserved ejection fraction (HFpEF). This report describes the baseline characteristics of the EMPEROR-Preserved cohort and compares it with patients enrolled in prior HFpEF trials. METHODS:EMPER...

journal_title：European journal of heart failure

authors： Anker SD,Butler J,Filippatos G,Khan MS,Ferreira JP,Bocchi E,Böhm M,Rocca HPB,Choi DJ,Chopra V,Chuquiure E,Giannetti N,Gomez-Mesa JE,Janssens S,Januzzi JL,Gonzalez-Juanatey JR,Merkely B,Nicholls SJ,Perrone SV,Piña IL

更新日期：2020-11-29 00:00:00

abstract：OBJECTIVE:To achieve angiogenic interaction between VEGF(165) and angiopoietin-1 (Ang-1) using a novel adenoviral bicistronic vector (Ad-Bic) encoding the two factors and delivered ex vivo using sex-mismatched human skeletal myoblasts. METHODS AND RESULTS:A myocardial infarction model was developed in 29 female pigs; ...

journal_title：European journal of heart failure

authors： Ye L,Haider HKh,Jiang S,Tan RS,Ge R,Law PK,Sim EK

更新日期：2007-01-01 00:00:00

abstract：AIMS:Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity. Synthetic LXR agonists have been evaluated for their efficacy in the cardiovascular system; however, they elicit prolipogenic side effects which substantially limit their therapeutic use. AZ876 is a novel high-affinity LXR ...

journal_title：European journal of heart failure

authors： Cannon MV,Yu H,Candido WM,Dokter MM,Lindstedt EL,Silljé HH,van Gilst WH,de Boer RA

更新日期：2015-03-01 00:00:00

abstract：:The AdaptResponse trial is designed to test the hypothesis that preferential adaptive left ventricular-only pacing with the AdaptivCRT® algorithm reduces the incidence of the combined endpoint of all-cause mortality and intervention for heart failure (HF) decompensation, compared with conventional cardiac resynchroniz...

journal_title：European journal of heart failure

authors： Filippatos G,Birnie D,Gold MR,Gerritse B,Hersi A,Jacobs S,Kusano K,Leclercq C,Mullens W,Wilkoff BL,AdaptResponse Investigators.

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...

journal_title：European journal of heart failure

authors： Jónsdóttir S,Andersen KK,Sigurosson AF,Sigurosson SB

更新日期：2006-01-01 00:00:00

abstract：:Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...

journal_title：European journal of heart failure

authors： Silverberg DS,Wexler D,Iaina A,Schwartz D

更新日期：2008-09-01 00:00:00