Cardiomyocyte-restricted over-expression of C-type natriuretic peptide prevents cardiac hypertrophy induced by myocardial infarction in mice.

abstract：AIMS:Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced...

journal_title：European journal of heart failure

authors： Dickinson BA,Semus HM,Montgomery RL,Stack C,Latimer PA,Lewton SM,Lynch JM,Hullinger TG,Seto AG,van Rooij E

更新日期：2013-06-01 00:00:00

abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

journal_title：European journal of heart failure

authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

更新日期：2009-04-01 00:00:00

abstract：AIMS:To determine the impact of internationally recognized criteria for the diagnosis of heart failure with preserved ejection fraction (HF-PEF) on the feasibility of recruitment into a HF-PEF trial. METHODS AND RESULTS:We reviewed the medical records of 5883 consecutive patients admitted with heart failure across eig...

journal_title：European journal of heart failure

authors： Patel HC,Hayward C,di Mario C,Cowie MR,Lyon AR,Rosen SD

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Crataegus preparations have been used for centuries especially in Europe. To date, no proper data on their efficacy and safety as an add-on-treatment are available. Therefore a large morbidity/mortality trial was performed. AIM:To investigate the efficacy and safety of an add-on treatment with Crataegus ext...

journal_title：European journal of heart failure

authors： Holubarsch CJ,Colucci WS,Meinertz T,Gaus W,Tendera M,Survival and Prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group.

更新日期：2008-12-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：AIMS:Left ventricular contractile reserve is a prognostic indicator for adverse outcome in patients with severe chronic heart failure with reduced ejection fraction (HFrEF). We investigated the dobutamine-induced changes of LV multidimensional deformation and their predictive value for cardiac mortality of patients wit...

journal_title：European journal of heart failure

authors： Paraskevaidis IA,Ikonomidis I,Simitsis P,Parissis J,Stasinos V,Makavos G,Lekakis J

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Regional presynaptic sympathetic innervation varies considerably in the cardiomyopathic human heart, as shown in previous studies in vivo and in vitro. The goal of the present study was to correlate markers of presynaptic sympathetic innervation with local measurement of the postsynaptic beta-adrenergic syst...

journal_title：European journal of heart failure

authors： Ungerer M,Weig HJ,Kübert S,Overbeck M,Bengel F,Schömig A,Schwaiger M

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The rate constant for global fatty acid influx (k(1)) was studied in 12 male patients with dilated cardiomyopathy (DCM). METHOD:10 normal subjects served as controls. 201-Thallium (201TI) and [123I]-phenyl-pentadecanoic acid (IPPA) were administered during bicycle exercise under fasting conditions. RESULTS...

journal_title：European journal of heart failure

authors： Miche E,Radzewitz A,Notohamiprodjo G,Baller D,Kloppe A,Eckert S,Gleichmann U

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Nuclear factor kappa B (NF-kappaB) is activated by several factors, which increase the inflammatory response, and this activation, in turn, leads to the expression of several genes such as cytokines, and may play an important role in cardiovascular diseases. AIMS:The aim of the study is to examine the effec...

journal_title：European journal of heart failure

authors： Matsumori A,Nunokawa Y,Yamaki A,Yamamoto K,Hwang MW,Miyamoto T,Hara M,Nishio R,Kitaura-Inenaga K,Ono K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The epidemiology of heart failure in Arabia, with a population different from the West in cultural and ethnic origin, has not been studied before. AIMS:To determine the prevalence and aetiologies of symptomatic heart failure in an indigenous Arab population over a 3-year period. METHODS:All patients with h...

journal_title：European journal of heart failure

authors： Agarwal AK,Venugopalan P,de Bono D

更新日期：2001-06-01 00:00:00

abstract：AIM:Data are scant on the incidence and prognosis of heart failure (HF) with normal ejection fraction (HFNEF, EF >49%) in an acute myocardial infarction (AMI) setting. The aim of this study was to examine incidence and predictors of HFNEF during an index acute myocardial infarction (AMI) and its subsequent associations...

journal_title：European journal of heart failure

authors： Desta L,Jernberg T,Spaak J,Hofman-Bang C,Persson H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic heart failure (CHF) have frequent episodes of exacerbation leading to recurrent hospitalization. AIMS:To explore factors related to patients seeking care for worsening CHF. METHODS:Eighty-eight patients diagnosed with a deteriorating CHF condition were interviewed. Data were analysed ...

journal_title：European journal of heart failure

authors： Patel H,Shafazand M,Schaufelberger M,Ekman I

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To investigate in vivo effects of long-term selective beta1-blockade on cardiac energy metabolism, remodelling, function and plasma cytokines in a rat model of post-infarct congestive heart failure (CHF). METHODS:Myocardial infarction (MI) was induced in male rats by ligation of the left coronary artery. Thr...

journal_title：European journal of heart failure

authors： Omerovic E,Bollano E,Soussi B,Waagstein F

更新日期：2003-12-01 00:00:00

abstract：AIMS:Exercise-derived parameters, specifically peak exercise oxygen uptake (peak VO2 ) and minute ventilation/carbon dioxide relationship slope (VE/VCO2 slope), have a pivotal prognostic value in heart failure (HF). It is unknown how the prognostic threshold of peak VO2 and VE/VCO2 slope has changed over the last 20 ye...

journal_title：European journal of heart failure

authors： Paolillo S,Veglia F,Salvioni E,Corrà U,Piepoli M,Lagioia R,Limongelli G,Sinagra G,Cattadori G,Scardovi AB,Metra M,Senni M,Bonomi A,Scrutinio D,Raimondo R,Emdin M,Magrì D,Parati G,Re F,Cicoira M,Minà C,Correale M

更新日期：2019-02-01 00:00:00

abstract：AIMS:The aim of this study was to investigate the prognostic impact of right ventricular (RV) size in patients with chronic heart failure. METHODS AND RESULTS:Normal volunteers (n = 80) and patients (n = 380) with left ventricular (LV) ejection fraction <45% on echocardiography and on optimal treatment for heart failu...

journal_title：European journal of heart failure

authors： Bourantas CV,Loh HP,Bragadeesh T,Rigby AS,Lukaschuk EI,Garg S,Tweddel AC,Alamgir FM,Nikitin NP,Clark AL,Cleland JG

更新日期：2011-01-01 00:00:00

abstract：AIM:Mineralocorticoid receptor antagonists (MRAs) improve outcomes in heart failure with reduced ejection fraction (HFrEF), but are underutilized. Hyperkalaemia may be one reason, but the underlying reasons for underuse are unknown. The aim of this study was to investigate the independent predictors of MRA underuse in ...

journal_title：European journal of heart failure

authors： Savarese G,Carrero JJ,Pitt B,Anker SD,Rosano GMC,Dahlström U,Lund LH

更新日期：2018-09-01 00:00:00

abstract：AIMS:The present study aimed to assess the association between left atrial (LA) structure and function and the risk for cardiovascular (CV) death or heart failure (HF) hospitalization in a population with atrial fibrillation (AF). METHODS AND RESULTS:In a prospective echocardiographic substudy of the Effective Anticoa...

journal_title：European journal of heart failure

authors： Inciardi RM,Giugliano RP,Claggett B,Gupta DK,Chandra A,Ruff CT,Antman EM,Mercuri MF,Grosso MA,Braunwald E,Solomon SD,ENGAGE AF-TIMI 48 Investigators.

更新日期：2019-12-01 00:00:00

abstract：AIMS:Mutations in the lamin A/C gene (LMNA) cause a variety of clinical phenotypes, including dilated cardiomyopathy. LMNA is one of the most prevalent mutated genes in dilated cardiomyopathy, and is associated with a high risk of arrhythmias, sudden cardiac death, and heart failure. There are few data on the impact of...

journal_title：European journal of heart failure

authors： van Rijsingen IA,Nannenberg EA,Arbustini E,Elliott PM,Mogensen J,Hermans-van Ast JF,van der Kooi AJ,van Tintelen JP,van den Berg MP,Grasso M,Serio A,Jenkins S,Rowland C,Richard P,Wilde AA,Perrot A,Pankuweit S,Zwinderman

更新日期：2013-04-01 00:00:00

abstract：AIMS:To investigate the annual hospitalization rate and seasonal variation in confirmed heart failure (HF) admissions. METHODS AND RESULTS:Records from all admissions to one hospital during 1 year with a HF diagnostic code were reviewed. From 1953 admissions, 595 were excluded because they did not fulfill the diagnost...

journal_title：European journal of heart failure

authors： Martínez-Sellés M,García Robles JA,Prieto L,Serrano JA,Muñoz R,Frades E,Almendral J

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Heart failure with preserved or mildly reduced ejection fraction (HFpEF) is common and, to date, therapeutic options are limited. Increased left atrial pressure is a key contributor to the symptoms associated with HFpEF, particularly during physical activity. We report the 30-day outcome of patients treated ...

journal_title：European journal of heart failure

authors： Søndergaard L,Reddy V,Kaye D,Malek F,Walton A,Mates M,Franzen O,Neuzil P,Ihlemann N,Gustafsson F

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Primary desminopathies are caused by desmin gene [DES (MIM*125660)] mutations. The clinical spectrum includes pure myopathies, cardiomuscular diseases and cardiomyopathies. Patients with restrictive cardiomyopathy (RCM) plus atrioventricular block (AVB) due to DES defects are frequently unrecognized unless d...

journal_title：European journal of heart failure

authors： Arbustini E,Pasotti M,Pilotto A,Pellegrini C,Grasso M,Previtali S,Repetto A,Bellini O,Azan G,Scaffino M,Campana C,Piccolo G,Viganò M,Tavazzi L

更新日期：2006-08-01 00:00:00

abstract：:It is well known that atrial fibrillation can lead to heart failure, and is attributed to rapid ventricular rate (tachycardia-induced cardiomyopathy). Some recent studies suggest the possible existence of an intrinsic left-ventricular factor related to atrial fibrillation, irrespective of other elements. In order to d...

journal_title：European journal of heart failure

authors： Jourdain P,Bellorini M,Funck F,Fulla Y,Guillard N,Loiret J,Thebault B,Sadeg N,Desnos M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To determine the acute vasodilator effect of sublingual sildenafil in heart transplant candidates with severe pulmonary hypertension due to severe left ventricular dysfunction (LVD). BACKGROUND:Pulmonary hypertension confers an increased risk of early graft failure. PATIENTS AND METHODS:Seven patients, (mea...

journal_title：European journal of heart failure

authors： Angel Gómez-Sánchez M,Saenz De La Calzada C,Escribano Subías P,Francisco Delgado Jiménez J,Lázaro Salvador M,Albarrán González A,Cea Calvo L

更新日期：2004-08-01 00:00:00

abstract：:The RUSSLAN study, which randomised 504 patients with post-infarction heart failure in whom intravenous inotropic support might be deemed appropriate, was presented for the first time in a hotline session at the annual meeting of the Working Group on Heart Failure of the European Society of Cardiology. The study sugge...

journal_title：European journal of heart failure

authors： Gomes UC,Cleland JG

更新日期：1999-08-01 00:00:00

abstract：AIMS:We investigated the association between quantified metabolite, lipid and lipoprotein measures and incident heart failure hospitalisation (HFH) in the elderly, and examined whether circulating metabolic measures improve HFH prediction. METHODS AND RESULTS:Overall, 80 metabolic measures from the PROspective Study o...

journal_title：European journal of heart failure

authors： Delles C,Rankin NJ,Boachie C,McConnachie A,Ford I,Kangas A,Soininen P,Trompet S,Mooijaart SP,Jukema JW,Zannad F,Ala-Korpela M,Salomaa V,Havulinna AS,Welsh P,Würtz P,Sattar N

更新日期：2018-04-01 00:00:00

abstract：:This article provides information and a commentary on trials presented at the American Heart Association meeting held in November 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports should be considered as preliminary data, as analyses may change in the final publication. In R...

journal_title：European journal of heart failure

authors： Cleland JG,Freemantle N,Coletta AP,Clark AL

更新日期：2006-01-01 00:00:00

abstract：AIMS:In amyloid patients, cardiac involvement dramatically worsens functional capacity and prognosis. We sought to study how the cardiopulmonary exercise test (CPET) could help in functional assessment and risk stratification of patients with cardiac amyloidosis (CA). METHODS AND RESULTS:We carried out a multicentre s...

journal_title：European journal of heart failure

authors： Nicol M,Deney A,Lairez O,Vergaro G,Emdin M,Carecci A,Inamo J,Montfort A,Neviere R,Damy T,Harel S,Royer B,Baudet M,Cohen-Solal A,Arnulf B,Logeart D

更新日期：2020-10-02 00:00:00

abstract：AIMS:Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity. Synthetic LXR agonists have been evaluated for their efficacy in the cardiovascular system; however, they elicit prolipogenic side effects which substantially limit their therapeutic use. AZ876 is a novel high-affinity LXR ...

journal_title：European journal of heart failure

authors： Cannon MV,Yu H,Candido WM,Dokter MM,Lindstedt EL,Silljé HH,van Gilst WH,de Boer RA

更新日期：2015-03-01 00:00:00

abstract：AIMS:Most studies on acute heart failure (HF) exploring the relationship between admissions to hospital for HF and subsequent outcomes have focused only on HF coded as the primary diagnosis, but many other patients have admissions complicated by HF requiring attention. Failure to quantify the total hospital burden of H...

journal_title：European journal of heart failure

authors： Shoaib A,Farag M,Nasir M,John J,Gupta S,Pellicori P,Antony R,Perveen R,Rigby A,Goode KM,Yassin A,Clark AL,Cleland JG

更新日期：2016-05-01 00:00:00