Heart failure update.

Abstract:

:The RUSSLAN study, which randomised 504 patients with post-infarction heart failure in whom intravenous inotropic support might be deemed appropriate, was presented for the first time in a hotline session at the annual meeting of the Working Group on Heart Failure of the European Society of Cardiology. The study suggested that levosimendan, a new calcium sensitising agent, could be used safely in patients with post-infarction heart failure in the absence of severe hypotension and that it appeared to improve symptoms and survival. If these results can be confirmed it would render it unique among intravenous inotropic agents.

journal_name

Eur J Heart Fail

authors

Gomes UC,Cleland JG

doi

10.1016/s1388-9842(99)00040-9

keywords:

subject

Has Abstract

pub_date

1999-08-01 00:00:00

pages

301-2

issue

3

eissn

1388-9842

issn

1879-0844

pii

S1388-9842(99)00040-9

journal_volume

1

pub_type

临床试验,杂志文章,随机对照试验
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    abstract:BACKGROUND:Heart failure is common in diabetes and ischaemic heart disease is the most likely link. Still, it has been suggested that the relation extends beyond such disease. METHODS:7060 subjects with two or more visits in the Reykjavík Study were followed--during 30 years from 1967. All underwent oral glucose toler...

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    authors: Thrainsdottir IS,Aspelund T,Gudnason V,Malmberg K,Sigurdsson G,Thorgeirsson G,Hardarson T,Rydén L

    更新日期:2007-10-01 00:00:00

  • Evaluation of kidney function throughout the heart failure trajectory - a position statement from the Heart Failure Association of the European Society of Cardiology.

    abstract::Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney function was primarily assessed by serum creatinine and the calculation of estimated glomerular filtration rate. An increase in serum creatinine, also termed wo...

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    authors: Mullens W,Damman K,Testani JM,Martens P,Mueller C,Lassus J,Tang WHW,Skouri H,Verbrugge FH,Orso F,Hill L,Ural D,Lainscak M,Rossignol P,Metra M,Mebazaa A,Seferovic P,Ruschitzka F,Coats A

    更新日期:2020-04-01 00:00:00

  • Which patients with heart failure should receive specialist palliative care?

    abstract:AIMS:We investigated which patients with heart failure (HF) should receive specialist palliative care (SPC) by first creating a definition of need for SPC in patients hospitalised with HF using patient-reported outcome measures (PROMs) and then testing this definition using the outcome of days alive and out of hospital...

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    authors: Campbell RT,Petrie MC,Jackson CE,Jhund PS,Wright A,Gardner RS,Sonecki P,Pozzi A,McSkimming P,McConnachie A,Finlay F,Davidson P,Denvir MA,Johnson MJ,Hogg KJ,McMurray JJV

    更新日期:2018-09-01 00:00:00

  • Echocardiographic quantification of regional deformation helps to distinguish isolated left ventricular non-compaction from dilated cardiomyopathy.

    abstract:AIMS:Pronounced trabeculation is presented in both left ventricular non-compaction (LVNC) and dilated cardiomyopathy (DCM), which sometimes makes the differentiation difficult. We hypothesized that echocardiographic deformation analysis would help to differentiate these two cardiomyopathies. METHODS AND RESULTS:We inv...

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    更新日期:2012-02-01 00:00:00

  • Levosimendan improves renal function in acute decompensated heart failure: possible underlying mechanisms.

    abstract:AIMS:The cardio-renal syndrome plays a critical role in acute heart failure (HF). Levosimendan, an inodilator drug, has a positive but controversial effect on kidney. Our aim was to evaluate its effects on both renal and systemic haemodynamic parameters as well as on renal function, explaining the possible mechanisms i...

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    pub_type: 杂志文章,随机对照试验

    doi:10.1002/ejhf.9

    authors: Fedele F,Bruno N,Brasolin B,Caira C,D'Ambrosi A,Mancone M

    更新日期:2014-03-01 00:00:00

  • Endomyocardial miR-133a levels correlate with myocardial inflammation, improved left ventricular function, and clinical outcome in patients with inflammatory cardiomyopathy.

    abstract:AIMS:Inflammatory heart disease represents an important cause of chronic dilated cardiomyopathy (DCM). Predicting the clinical course of patients with inflammatory cardiomyopathy (iCMP) is difficult, and the prognostic value of current biological markers remains controversial. We tested whether expression of selected m...

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    doi:10.1002/ejhf.579

    authors: Besler C,Urban D,Watzka S,Lang D,Rommel KP,Kandolf R,Klingel K,Thiele H,Linke A,Schuler G,Adams V,Lurz P

    更新日期:2016-12-01 00:00:00

  • N-terminal pro-brain natriuretic peptide for discriminating between cardiac and non-cardiac dyspnoea.

    abstract:AIM:Evaluation of N-terminal pro-brain natriuretic peptide (NT-proBNP) to confirm or disprove heart failure in community patients complaining of dyspnoea. METHODS AND RESULTS:General practitioners referred 345 consecutive patients complaining of dyspnoea to our hospital-based clinic, where a diagnosis was established ...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/j.ejheart.2003.10.003

    authors: Nielsen LS,Svanegaard J,Klitgaard NA,Egeblad H

    更新日期:2004-01-01 00:00:00

  • Does the physical examination still have a role in patients with suspected heart failure?

    abstract:AIMS:The prognostic value of signs of congestion in patients suspected of having chronic heart failure (CHF) is unknown. Our objectives were to define their prevalence and specificity in diagnosing CHF and to determine their prognostic value in patients in a community heart failure clinic. METHODS AND RESULTS:Analysis...

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    pub_type: 杂志文章,多中心研究

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    authors: Damy T,Kallvikbacka-Bennett A,Zhang J,Goode K,Buga L,Hobkirk J,Yassin A,Dubois-Randé JL,Hittinger L,Cleland JG,Clark AL

    更新日期:2011-12-01 00:00:00

  • Autoantibodies against cardiac troponin I in patients with congestive heart failure.

    abstract:AIMS:In this randomized, double-blind clinical study, we investigated the relationship between autoantibodies against cardiac troponin I (cTnI) and disease severity in elderly congestive heart failure (CHF) patients before and after titration of beta-blocker therapy. METHODS AND RESULTS:Anti-cTnI, cTnI, and N-terminal...

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    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurjhf/hfq088

    authors: Düngen HD,Platzeck M,Vollert J,Searle J,Müller C,Reiche J,Mehrhof F,Müller R,Möckel M

    更新日期:2010-07-01 00:00:00

  • Oral sucrosomial iron improves exercise capacity and quality of life in heart failure with reduced ejection fraction and iron deficiency: a non-randomized, open-label, proof-of-concept study.

    abstract:AIMS:Oral sucrosomial iron (SI) combines enhanced bioavailability and tolerance compared to conventional oral iron along with similar efficacy compared to intravenous iron in several conditions associated with iron deficiency (ID). METHODS AND RESULTS:In this non-randomized, open-label study, we sought to evaluate pro...

    journal_title:European journal of heart failure

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    doi:10.1002/ejhf.2092

    authors: Karavidas A,Troganis E,Lazaros G,Balta D,Karavidas IN,Polyzogopoulou E,Parissis J,Farmakis D

    更新日期:2021-01-09 00:00:00

  • Decreasing trends in the incidence of heart failure after acute myocardial infarction from 1993-2004: a study of 175,216 patients with a first acute myocardial infarction in Sweden.

    abstract:AIMS:To investigate temporal trends in the risk of heart failure (HF) complicating acute myocardial infarction (AMI) and to determine whether these trends differ by gender or age. METHODS AND RESULTS:The national Swedish hospital discharge and death registries from 1993 to 2004 were used to calculate age- and gender-s...

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    doi:10.1093/eurjhf/hfq205

    authors: Shafazand M,Rosengren A,Lappas G,Swedberg K,Schaufelberger M

    更新日期:2011-02-01 00:00:00

  • Selective beta1-blockade attenuates post-infarct remodelling without improvement in myocardial energy metabolism and function in rats with heart failure.

    abstract:OBJECTIVE:To investigate in vivo effects of long-term selective beta1-blockade on cardiac energy metabolism, remodelling, function and plasma cytokines in a rat model of post-infarct congestive heart failure (CHF). METHODS:Myocardial infarction (MI) was induced in male rats by ligation of the left coronary artery. Thr...

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    pub_type: 杂志文章

    doi:10.1016/s1388-9842(03)00153-3

    authors: Omerovic E,Bollano E,Soussi B,Waagstein F

    更新日期:2003-12-01 00:00:00

  • Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction.

    abstract:AIMS:Women are more likely to develop heart failure with preserved ejection fraction (HFpEF) than men. We studied the relationship between sex and cardiovascular structure and function in patients with HFpEF. METHODS AND RESULTS:The study included 279 participants from the PARAMOUNT study (57% women) with analysable b...

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    pub_type: 杂志文章

    doi:10.1002/ejhf.67

    authors: Gori M,Lam CS,Gupta DK,Santos AB,Cheng S,Shah AM,Claggett B,Zile MR,Kraigher-Krainer E,Pieske B,Voors AA,Packer M,Bransford T,Lefkowitz M,McMurray JJ,Solomon SD,PARAMOUNT Investigators.

    更新日期:2014-05-01 00:00:00

  • The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects.

    abstract:AIMS:Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity. Synthetic LXR agonists have been evaluated for their efficacy in the cardiovascular system; however, they elicit prolipogenic side effects which substantially limit their therapeutic use. AZ876 is a novel high-affinity LXR ...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.243

    authors: Cannon MV,Yu H,Candido WM,Dokter MM,Lindstedt EL,Silljé HH,van Gilst WH,de Boer RA

    更新日期:2015-03-01 00:00:00

  • Right ventricular dysfunction is an independent predictor for mortality in ST-elevation myocardial infarction patients presenting with cardiogenic shock on admission.

    abstract:AIMS:Despite improvement in prognosis for ST-elevation myocardial infarction (STEMI) patients, mortality remains high in STEMI patients presenting with cardiogenic shock (CS). Right ventricular (RV) dysfunction is an established independent predictor for adverse prognosis in STEMI patients without CS. The purpose of ou...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1093/eurjhf/hfp204

    authors: Engström AE,Vis MM,Bouma BJ,van den Brink RB,Baan J Jr,Claessen BE,Kikkert WJ,Sjauw KD,Meuwissen M,Koch KT,de Winter RJ,Tijssen JG,Piek JJ,Henriques JP

    更新日期:2010-03-01 00:00:00

  • Combining the ventilatory response to exercise and peak oxygen consumption is no better than peak oxygen consumption alone in predicting mortality in chronic heart failure.

    abstract:BACKGROUND:A low peak oxygen uptake (pVO(2)) and steep VE/VCO(2) slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to a more accurate predictor of prognosis than using either alone. METHOD...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/j.ejheart.2007.10.010

    authors: Ingle L,Witte KK,Cleland JG,Clark AL

    更新日期:2008-01-01 00:00:00

  • Plasma B-type natriuretic peptide and anti-inflammatory cytokine interleukin-10 levels predict adverse clinical outcome in chronic heart failure patients with depressive symptoms: a 1-year follow-up study.

    abstract:AIMS:To assess the prognostic value of a wide spectrum of neurohormonal and inflammatory markers along with functional status and exercise capacity, in hospitalized chronic heart failure (CHF) patients with depressive symptoms. METHODS AND RESULTS:A total of 300 consecutive hospitalized CHF patients were screened for ...

    journal_title:European journal of heart failure

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    doi:10.1093/eurjhf/hfp125

    authors: Parissis JT,Farmakis D,Nikolaou M,Birmpa D,Bistola V,Paraskevaidis I,Ikonomidis I,Gaitani S,Venetsanou K,Filippatos G,Kremastinos DT

    更新日期:2009-10-01 00:00:00

  • A functional variant of the neuropeptide S receptor-1 gene modulates clinical outcomes and healthcare utilization in patients with systolic heart failure: results from the Interdisciplinary Network Heart Failure (INH) Study.

    abstract:AIMS:Psychopathologies may occur in heart failure (HF) and can be associated with adverse outcomes. Amongst neuropeptide S receptor gene functional sequence variants, the T-allele [asparagine(107)isoleucine, NPSR1 rs324981] has been identified as a risk factor for increased anxiety/overinterpretation of bodily symptoms...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.706

    authors: Angermann CE,Kaspar M,Marx A,Kittel-Schneider S,Menhofer D,Störk S,Ertl G,Domschke K,Deckert J,Reif A

    更新日期:2017-03-01 00:00:00

  • Baseline Characteristics of Patients with Heart Failure with Preserved Ejection Fraction in the EMPEROR-Preserved Trial.

    abstract:BACKGROUND:EMPEROR-Preserved is an ongoing trial evaluating the effect of empagliflozin in patients with heart failure with preserved ejection fraction (HFpEF). This report describes the baseline characteristics of the EMPEROR-Preserved cohort and compares it with patients enrolled in prior HFpEF trials. METHODS:EMPER...

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    pub_type: 杂志文章

    doi:10.1002/ejhf.2064

    authors: Anker SD,Butler J,Filippatos G,Khan MS,Ferreira JP,Bocchi E,Böhm M,Rocca HPB,Choi DJ,Chopra V,Chuquiure E,Giannetti N,Gomez-Mesa JE,Janssens S,Januzzi JL,Gonzalez-Juanatey JR,Merkely B,Nicholls SJ,Perrone SV,Piña IL

    更新日期:2020-11-29 00:00:00

  • Effect of warfarin on survival in patients with concomitant left ventricular systolic dysfunction and pulmonary hypertension: a population cohort study.

    abstract:BACKGROUND:The use of oral anticoagulation in patients with heart failure in sinus rhythm remains controversial as previous large randomized controlled trials (RCTs) have not shown a survival benefit. However, heterogeneity exists among heart failure patients and it is possible that high-risk subgroups may benefit from...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.199

    authors: Goudie A,Elder D,Deshmukh H,Szwejkowski BR,Lang CC,George J

    更新日期:2015-01-01 00:00:00

  • Effect of dofetilide on QT dispersion and the prognostic implications of changes in QT dispersion for patients with congestive heart failure.

    abstract:AIMS:Drug-induced changes in QT dispersion may be a way of detecting harmful repolarisation abnormalities for patients receiving antiarrhythmic drugs affecting ventricular repolarisation. METHODS AND RESULTS:In 463 congestive heart failure (CHF) patients enrolled in the Danish Investigations Of Arrhythmia and Mortalit...

    journal_title:European journal of heart failure

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1388-9842(01)00235-5

    authors: Brendorp B,Elming H,Jun L,Køber L,Torp-Pedersen C,DIAMOND Study Group. Danish Investigations Of Arrhythmia and Mortality On Dofetilide.

    更新日期:2002-03-01 00:00:00

  • Incidence of cancer in patients with chronic heart failure: a long-term follow-up study.

    abstract:AIMS:With improvement in survival of chronic heart failure (HF), the clinical importance of co-morbidity is increasing. The aim of this study was to assess the incidence and risk of cancer and all-cause mortality in a large Danish HF cohort. METHODS AND RESULTS:A total of 9307 outpatients with verified HF without a pr...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.472

    authors: Banke A,Schou M,Videbaek L,Møller JE,Torp-Pedersen C,Gustafsson F,Dahl JS,Køber L,Hildebrandt PR,Gislason GH

    更新日期:2016-03-01 00:00:00

  • Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure.

    abstract:AIMS:To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF). METHODS AND RESULTS:Central venous pressure was determined non-invasively using high-resoluti...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1093/eurjhf/hfq024

    authors: Uthoff H,Thalhammer C,Potocki M,Reichlin T,Noveanu M,Aschwanden M,Staub D,Arenja N,Socrates T,Twerenbold R,Mutschmann-Sanchez S,Heinisch C,Jaeger KA,Mebazaa A,Mueller C

    更新日期:2010-05-01 00:00:00

  • Preferences of heart failure patients in daily clinical practice: quality of life or longevity?

    abstract:AIMS:Knowledge of patient preferences is vital for delivering optimal healthcare. This study uses utility measurement to assess the preferences of heart failure (HF) patients regarding quality of life or longevity. The utility approach represents the perspective of a patient; facilitates the combination of mortality, m...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1093/eurjhf/hft071

    authors: Kraai IH,Vermeulen KM,Luttik ML,Hoekstra T,Jaarsma T,Hillege HL

    更新日期:2013-10-01 00:00:00

  • Plasma N-terminal pro BNP and cardiotrophin-1 are elevated in aortic stenosis.

    abstract:BACKGROUND:Echocardiography with Doppler examination of the aortic valve provides a very accurate assessment of the transvalvular gradient and is used to monitor progression of aortic stenosis (AS). Plasma brain natriuretic peptide (BNP) has been shown to correlate with end-systolic wall stress in patients with AS. AI...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/s1388-9842(00)00074-x

    authors: Talwar S,Downie PF,Squire IB,Davies JE,Barnett DB,Ng LL

    更新日期:2001-01-01 00:00:00

  • Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.

    abstract:BACKGROUND:Platelet-endothelial interactions modulated by adhesion molecules, may play an important role in the pathogenesis of congestive heart failure (CHF). Soluble levels of these molecules and platelet-derived substances are reportedly elevated in patients with CHF. However, no data are available on the plasma lev...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/s1388-9842(99)00029-x

    authors: Serebruany VL,Murugesan SR,Pothula A,Atar D,Lowry DR,O'Connor CM,Gurbel PA

    更新日期:1999-08-01 00:00:00

  • Usefulness of anti-oxidized LDL antibody determination for assessment of clinical control in patients with heart failure.

    abstract:BACKGROUND:It has been suggested that oxidative stress may play a role in the pathogenesis of heart failure, this may have potential implications for therapeutic strategies. However, measures of oxidative stress are subject to confounding inaccuracies. IgG antibodies to oxidized LDL reflect exposure to the lipoprotein ...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/j.ejheart.2005.04.015

    authors: George J,Wexler D,Roth A,Barak T,Sheps D,Keren G

    更新日期:2006-01-01 00:00:00

  • Heart failure and chronic obstructive pulmonary disease: diagnostic pitfalls and epidemiology.

    abstract::Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally...

    journal_title:European journal of heart failure

    pub_type: 杂志文章,评审

    doi:10.1093/eurjhf/hfn013

    authors: Hawkins NM,Petrie MC,Jhund PS,Chalmers GW,Dunn FG,McMurray JJ

    更新日期:2009-02-01 00:00:00

  • Sex differences in mineralocorticoid receptor antagonist trials: a pooled analysis of three large clinical trials.

    abstract:AIMS:Women with heart failure (HF) are under-represented in individual randomized clinical trials (RCTs). Little is known about sex-specific treatment effects in HF medications. We evaluated sex differences in the response to mineralocorticoid receptor antagonists (MRAs) in major HF MRA trials, including a broad spectr...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.1740

    authors: Rossello X,Ferreira JP,Pocock SJ,McMurray JJV,Solomon SD,Lam CSP,Girerd N,Pitt B,Rossignol P,Zannad F

    更新日期:2020-05-01 00:00:00

  • Optimized Implementation of cardiac resynchronization therapy - a call for action for referral and optimization of care.

    abstract::Cardiac resynchronization therapy (CRT) is one of the most effective therapies for heart failure with reduced ejection fraction and leads to improved quality of life, reductions in heart failure hospitalization rates and reduces all-cause mortality. Nevertheless, up to two-thirds of eligible patients are not referred ...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1002/ejhf.2046

    authors: Mullens W,Auricchio A,Martens P,Witte K,Cowie MR,Delgado V,Dickstein K,Linde C,Vernooy K,Leyva F,Bauersachs J,Israel CW,Lund L,Donal E,Boriani G,Jaarsma T,Berruezo A,Traykov V,Yousef Z,Kalarus Z,Nielsen JC,Steff

    更新日期:2020-11-02 00:00:00