Evolving concepts in dilated cardiomyopathy.

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a measure of acute kidney injury. Renal dysfunction portends significant risk after discharge from acute heart failure (AHF). Thus, a sensitive marker of renal injury might also help to risk stratify HF patients. METHODS AND RESULTS:GALLANT [NGAL EvaLuation Alo...

journal_title：European journal of heart failure

authors： Maisel AS,Mueller C,Fitzgerald R,Brikhan R,Hiestand BC,Iqbal N,Clopton P,van Veldhuisen DJ

更新日期：2011-08-01 00:00:00

abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...

journal_title：European journal of heart failure

authors： Miller WL,Borgeson DD,Grantham JA,Luchner A,Redfield MM,Burnett JC Jr

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Beneficial effects of left ventricular (LV)-based pacing on acute hemodynamic parameters were reported in several series, but only a few studies examined the long-term effects of this new pacing procedure. AIMS:To assess long-term effects of permanent LV-based pacing on LV function and mitral regurgitation ...

journal_title：European journal of heart failure

authors： Etienne Y,Mansourati J,Touiza A,Gilard M,Bertault-Valls V,Guillo P,Boschat J,Blanc JJ

更新日期：2001-08-01 00:00:00

abstract：AIMS:Congestive heart failure (CHF) is associated with impaired renal function. Previously, we have demonstrated that rats with decompensated CHF exhibited exaggerated sensitivity to the adverse renal effects of increased increased intra-abdominal pressure (IAP) as compared with normal controls. This study tested wheth...

journal_title：European journal of heart failure

authors： Bishara B,Abu-Saleh N,Awad H,Ghrayeb N,Goltsman I,Aronson D,Khamaysi I,Assady S,Armaly Z,Haddad S,Haddad E,Abassi Z

更新日期：2012-10-01 00:00:00

abstract：AIMS:This study was designed to assess whether the prognostic significance of estimated glomerular filtration rate (eGFR) and left ventricular ejection fraction (LVEF) interact in populations with heart failure (HF) and myocardial infarction (MI). METHODS:Patients were recruited from four screening registers (N=18,010...

journal_title：European journal of heart failure

authors： Schou M,Torp-Pedersen C,Gustafsson F,Abdulla J,Kober L

更新日期：2008-07-01 00:00:00

abstract：:Heart rate not only predicts outcome but may also be a therapeutic target in patients with chronic heart failure. Several classes of pharmacological agents can be used to modulate heart rate, including beta-blockers, ivabradine, digoxin, amiodarone, and verapamil. Choice of agent will depend on heart rhythm, co-morbid...

journal_title：European journal of heart failure

authors： Dobre D,Borer JS,Fox K,Swedberg K,Adams KF,Cleland JG,Cohen-Solal A,Gheorghiade M,Gueyffier F,O'Connor CM,Fiuzat M,Patak A,Piña IL,Rosano G,Sabbah HN,Tavazzi L,Zannad F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic heart failure (CHF) have frequent episodes of exacerbation leading to recurrent hospitalization. AIMS:To explore factors related to patients seeking care for worsening CHF. METHODS:Eighty-eight patients diagnosed with a deteriorating CHF condition were interviewed. Data were analysed ...

journal_title：European journal of heart failure

authors： Patel H,Shafazand M,Schaufelberger M,Ekman I

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The role of AT1 receptors in myocardial ischemia/reperfusion injury is unclear. We, therefore, investigated the effects of the AT1 receptor antagonist irbesartan (Irb) in isolated hearts of selective myocardial AT1 overexpressing transgenic [transgenic(alphaMHC-hAT1)594-17] and Sprague-Dawley rats (SD) subje...

journal_title：European journal of heart failure

authors： Han H,Hoffmann S,Hu K,Ertl G

更新日期：2002-03-01 00:00:00

abstract：AIM:Evaluation of N-terminal pro-brain natriuretic peptide (NT-proBNP) to confirm or disprove heart failure in community patients complaining of dyspnoea. METHODS AND RESULTS:General practitioners referred 345 consecutive patients complaining of dyspnoea to our hospital-based clinic, where a diagnosis was established ...

journal_title：European journal of heart failure

authors： Nielsen LS,Svanegaard J,Klitgaard NA,Egeblad H

更新日期：2004-01-01 00:00:00

abstract：AIMS:Acute heart failure is a high mortality disease and its pathophysiology is not completely understood. Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in angiotensin II and enkephalins cleavage. The aim of this study was to investigate the association of circulating DPP3 (cDPP3) levels and mortality in...

journal_title：European journal of heart failure

authors： Deniau B,Rehfeld L,Santos K,Dienelt A,Azibani F,Sadoune M,Kounde PR,Samuel JL,Tolpannen H,Lassus J,Harjola VP,Vodovar N,Bergmann A,Hartmann O,Mebazaa A,Blet A

更新日期：2020-02-01 00:00:00

abstract：:Renal dysfunction in heart failure with preserved ejection fraction (HFpEF) is common and is associated with increased mortality. Impaired renal function is also a risk factor for developing HFpEF. A new paradigm for HFpEF, proposing a sequence of events leading to myocardial remodelling and dysfunction in HFpEF, was ...

journal_title：European journal of heart failure

authors： Ter Maaten JM,Damman K,Verhaar MC,Paulus WJ,Duncker DJ,Cheng C,van Heerebeek L,Hillege HL,Lam CS,Navis G,Voors AA

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Primary desminopathies are caused by desmin gene [DES (MIM*125660)] mutations. The clinical spectrum includes pure myopathies, cardiomuscular diseases and cardiomyopathies. Patients with restrictive cardiomyopathy (RCM) plus atrioventricular block (AVB) due to DES defects are frequently unrecognized unless d...

journal_title：European journal of heart failure

authors： Arbustini E,Pasotti M,Pilotto A,Pellegrini C,Grasso M,Previtali S,Repetto A,Bellini O,Azan G,Scaffino M,Campana C,Piccolo G,Viganò M,Tavazzi L

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of NT-proBNP in the emergency diagnosis and in-hospital monitoring of patients with acute dyspnoea and ventricular dysfunction. BACKGROUND:Misdiagnosis of heart failure (HF) is common in the urgent care setting using clinical diagnostic tests. Reports show that BNP is useful to diagno...

journal_title：European journal of heart failure

authors： Bayés-Genís A,Santaló-Bel M,Zapico-Muñiz E,López L,Cotes C,Bellido J,Leta R,Casan P,Ordóñez-Llanos J

更新日期：2004-03-15 00:00:00

abstract：:The use of erythropoietin (EPO) has revolutionized the treatment of anaemia associated with many conditions including chronic kidney disease (CKD). However, little is known of the cellular impact of EPO on the uraemic heart. The discovery that the EPO receptor (EPOR) is also expressed on non-haematopoietic cells inclu...

journal_title：European journal of heart failure

authors： Smith K,Semple D,Bhandari S,Seymour AM

更新日期：2009-08-01 00:00:00

abstract：AIMS:Incident heart failure (HF) continues to pose a common and serious problem. We sought to examine the value of echocardiographic predictors of new HF in a community-based elderly population at risk for HF, independent of and incremental to clinical evaluation. METHODS AND RESULTS:Asymptomatic patients ≥65 years ol...

journal_title：European journal of heart failure

authors： Yang H,Negishi K,Wang Y,Nolan M,Saito M,Marwick TH

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Plasma concentrations of atrial natriuretic peptides are correlated with atrial pressures, as are left ventricular ejection fraction and left ventricular filling abnormalities. AIMS:This study investigated the relation of atrial natriuretic peptides to both left ventricular systolic and diastolic function i...

journal_title：European journal of heart failure

authors： Wijbenga AA,Balk AH,Jonkman FA,Boomsma F,Simoons ML,Man in t Veld AJ

更新日期：1999-03-01 00:00:00

abstract：:Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally...

journal_title：European journal of heart failure

authors： Hawkins NM,Petrie MC,Jhund PS,Chalmers GW,Dunn FG,McMurray JJ

更新日期：2009-02-01 00:00:00

abstract：AIMS:Modulation of vagal tone using electrical vagal nerve stimulation or pharmacological acetylcholinesterase inhibition by donepezil exerts beneficial effects in an animal model of chronic heart failure (CHF). Considering different treatment mechanisms underlying renin-angiotensin system (RAS) suppression and parasym...

journal_title：European journal of heart failure

authors： Li M,Zheng C,Kawada T,Inagaki M,Uemura K,Sugimachi M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:No specific guidelines exist on how to manage renal dysfunction (RD) in patients with chronic heart failure (CHF). AIMS:To identify the proportion of patients with moderate to severe RD and CHF who showed an improvement in their renal function in response to a systematic management algorithm. METHODS:Stabl...

journal_title：European journal of heart failure

authors： de Silva R,Nikitin NP,Witte KK,Rigby AS,Loh H,Nicholson A,Bhandari S,Clark AL,Cleland JG

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:A low peak oxygen uptake (pVO(2)) and steep VE/VCO(2) slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to a more accurate predictor of prognosis than using either alone. METHOD...

journal_title：European journal of heart failure

authors： Ingle L,Witte KK,Cleland JG,Clark AL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The epidemiology of heart failure in Arabia, with a population different from the West in cultural and ethnic origin, has not been studied before. AIMS:To determine the prevalence and aetiologies of symptomatic heart failure in an indigenous Arab population over a 3-year period. METHODS:All patients with h...

journal_title：European journal of heart failure

authors： Agarwal AK,Venugopalan P,de Bono D

更新日期：2001-06-01 00:00:00

abstract：AIMS:The present study aimed to assess the association between left atrial (LA) structure and function and the risk for cardiovascular (CV) death or heart failure (HF) hospitalization in a population with atrial fibrillation (AF). METHODS AND RESULTS:In a prospective echocardiographic substudy of the Effective Anticoa...

journal_title：European journal of heart failure

authors： Inciardi RM,Giugliano RP,Claggett B,Gupta DK,Chandra A,Ruff CT,Antman EM,Mercuri MF,Grosso MA,Braunwald E,Solomon SD,ENGAGE AF-TIMI 48 Investigators.

更新日期：2019-12-01 00:00:00

abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

journal_title：European journal of heart failure

authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:In patients with heart failure and reduced left ventricular ejection fraction, angiotensin receptor blockers have been found to reduce mortality and morbidity and to prevent or reverse left ventricular remodelling, compared to optimized background treatment. In light of these data, The Heart failure Endpoint...

journal_title：European journal of heart failure

authors： Konstam MA,Poole-Wilson PA,Dickstein K,Drexler H,Justice SJ,Komajda M,Malbecq W,Martinez FA,Neaton JD,Riegger GA,Guptha S

更新日期：2008-09-01 00:00:00

abstract：AIMS:Insulin-dependent positive inotropic effects (PIE) are partially Ca(2+) independent. This mechanism is potentially glucose dependent. In contrast to most animal species, human myocardium expresses high levels of sodium-glucose-transporter-1 (SGLT-1) mRNA besides the common glucose-transporters-1 and -4 (GLUT1, GLU...

journal_title：European journal of heart failure

authors： von Lewinski D,Gasser R,Rainer PP,Huber MS,Wilhelm B,Roessl U,Haas T,Wasler A,Grimm M,Bisping E,Pieske B

更新日期：2010-02-01 00:00:00

abstract：AIMS:To investigate the prognostic value of autonomic variables in patients with symptomatic chronic heart failure (HF) treated according to current recommendations. METHODS AND RESULTS:We analysed 24 h time-domain [standard deviation of all normal-to-normal RR intervals (SDNN)], frequency-domain [very low frequency a...

journal_title：European journal of heart failure

authors： La Rovere MT,Pinna GD,Maestri R,Barlera S,Bernardinangeli M,Veniani M,Nicolosi GL,Marchioli R,Tavazzi L,GISSI-HF Investigators.

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...

journal_title：European journal of heart failure

authors： Kronborg MB,Mortensen PT,Kirkfeldt RE,Nielsen JC

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Clinical trials, the gold standard for the evaluation of new therapeutic strategies, may prove a drug to be beneficial, harmful or neutral according to its effect on the end-point(s) under study. AIMS:To study the reaction and perspective of the patients participating in a clinical heart failure trial, part...

journal_title：European journal of heart failure

authors： Yuval R,Uziel K,Gordon N,Merdler A,Khader N,Karkabi B,Flugelman MY,Halon DA,Lewis BS

更新日期：2001-03-01 00:00:00

abstract：AIMS:In this randomized, double-blind clinical study, we investigated the relationship between autoantibodies against cardiac troponin I (cTnI) and disease severity in elderly congestive heart failure (CHF) patients before and after titration of beta-blocker therapy. METHODS AND RESULTS:Anti-cTnI, cTnI, and N-terminal...

journal_title：European journal of heart failure

authors： Düngen HD,Platzeck M,Vollert J,Searle J,Müller C,Reiche J,Mehrhof F,Müller R,Möckel M

更新日期：2010-07-01 00:00:00

abstract：UNLABELLED:Experimental data have shown that rIL2 has negative inotropic properties. This has not been investigated in humans with normal left ventricular function. Seventeen consecutive renal cell carcinoma patients who received rIL2 therapy because of dissemination were analyzed before and after treatment with a low ...

journal_title：European journal of heart failure

authors： Tio RA,Nieken J,de Vries EG,Pfeiffer C,de Jongste MJ,Pieper E,Moshage H,Limburg PC,Mulder NH

更新日期：2000-06-01 00:00:00