C-reactive protein, diastolic dysfunction, and risk of heart failure in patients with coronary disease: Heart and Soul Study.

Abstract:

BACKGROUND:High-sensitivity C-reactive protein (CRP) is an inflammatory marker that predicts coronary heart disease (CHD) and, in recent studies, incident heart failure (HF). Whether the association of inflammation with incident HF is explained by worse baseline left ventricular dysfunction or by underlying CHD is unknown. METHODS AND RESULTS:Serum CRP was measured in a cohort of 985 outpatients with established CHD from the Heart and Soul Study. During 3 years of follow-up, 15% of the participants with elevated CRP levels (>3 mg/L) were hospitalised for HF, compared with 7% of those with CRP

journal_name

Eur J Heart Fail

authors

Williams ES,Shah SJ,Ali S,Na BY,Schiller NB,Whooley MA

doi

10.1016/j.ejheart.2007.11.003

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

63-9

issue

1

eissn

1388-9842

issn

1879-0844

pii

S1388-9842(07)00470-9

journal_volume

10

pub_type

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