Abstract:
BACKGROUND:Acute dyspnoea as a presenting symptom is a frequent diagnostic challenge for physicians. The main differential diagnosis is between dyspnoea of cardiac and non-cardiac origin. Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method which can be used to assess pulmonary congestion. AIM:To evaluate the accuracy of ULCs for predicting dyspnoea of cardiac origin compared to natriuretic peptides. METHODS:We evaluated 149 patients admitted with acute dyspnoea. Chest sonography and NT-proBNP assessments were performed a maximum of 4 h apart and independently analyzed. ULCs were evaluated via cardiac probes placed on the anterior and lateral chest. Two independent physicians, blinded to ULCs and NT-proBNP findings, reviewed all the medical records to establish the aetiologic diagnosis of dyspnoea. RESULTS:Cardiogenic dyspnoea was confirmed in 122 patients and ruled-out in 27 patients. The number of ULCs was significantly correlated to NT-proBNP values (r=.69, p<.0001). Receiver operating characteristic analysis, showed an area under the curve of .893 for ULCs and .978 (p=.001) for NT-proBNP, in predicting the cardiac origin of dyspnoea. CONCLUSIONS:In patients admitted with acute dyspnoea, pulmonary congestion, sonographically imaged as ULCs, is significantly correlated to NT-proBNP values. The accuracy of ULCs in predicting the cardiac origin of dyspnoea is high.
journal_name
Eur J Heart Failjournal_title
European journal of heart failureauthors
Gargani L,Frassi F,Soldati G,Tesorio P,Gheorghiade M,Picano Edoi
10.1016/j.ejheart.2007.10.009subject
Has Abstractpub_date
2008-01-01 00:00:00pages
70-7issue
1eissn
1388-9842issn
1879-0844pii
S1388-9842(07)00430-8journal_volume
10pub_type
杂志文章abstract:AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...
journal_title:European journal of heart failure
pub_type: 杂志文章,多中心研究
doi:10.1093/eurjhf/hfp032
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:It has been suggested that oxidative stress may play a role in the pathogenesis of heart failure, this may have potential implications for therapeutic strategies. However, measures of oxidative stress are subject to confounding inaccuracies. IgG antibodies to oxidized LDL reflect exposure to the lipoprotein ...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2005.04.015
更新日期:2006-01-01 00:00:00
abstract:AIMS:We investigated the association between quantified metabolite, lipid and lipoprotein measures and incident heart failure hospitalisation (HFH) in the elderly, and examined whether circulating metabolic measures improve HFH prediction. METHODS AND RESULTS:Overall, 80 metabolic measures from the PROspective Study o...
journal_title:European journal of heart failure
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/ejhf.1076
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Nuclear factor kappa B (NF-kappaB) is activated by several factors, which increase the inflammatory response, and this activation, in turn, leads to the expression of several genes such as cytokines, and may play an important role in cardiovascular diseases. AIMS:The aim of the study is to examine the effec...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2003.10.007
更新日期:2004-03-01 00:00:00
abstract:AIMS:Impaired tissue perfusion is often observed in patients with acute heart failure. We tested whether low-dose nitroglycerin (NTG) improves microcirculatory perfusion in patients admitted for acute heart failure. METHODS AND RESULTS:In 20 acute heart failure patients, NTG was given as intravenous infusion at a fixe...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfp021
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Patients with chronic heart failure (CHF) have frequent episodes of exacerbation leading to recurrent hospitalization. AIMS:To explore factors related to patients seeking care for worsening CHF. METHODS:Eighty-eight patients diagnosed with a deteriorating CHF condition were interviewed. Data were analysed ...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2006.11.002
更新日期:2007-06-01 00:00:00
abstract:AIMS:To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF). METHODS AND RESULTS:Central venous pressure was determined non-invasively using high-resoluti...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfq024
更新日期:2010-05-01 00:00:00
abstract:AIMS:The Exercise Joins Education: Combined Therapy to Improve Outcomes in Newly-discharged Heart Failure (EJECTION-HF) study will evaluate the impact of a supervised exercise training programme (ETP) on clinical outcomes in recently hospitalized heart failure patients attending a disease management programme (DMP). Me...
journal_title:European journal of heart failure
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurjhf/hfr139
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...
journal_title:European journal of heart failure
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejheart.2005.05.002
更新日期:2006-01-01 00:00:00
abstract:AIMS:Urine proteome analysis (UPA) has already provided accurate discriminatory patterns of urinary peptides for renal disease, coronary artery disease, and asymptomatic LV diastolic dysfunction. UPA has now been used to characterize a discriminatory peptide biomarker pattern and establish a diagnostic classifier for h...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1002/ejhf.544
更新日期:2016-07-01 00:00:00
abstract::Heart rate not only predicts outcome but may also be a therapeutic target in patients with chronic heart failure. Several classes of pharmacological agents can be used to modulate heart rate, including beta-blockers, ivabradine, digoxin, amiodarone, and verapamil. Choice of agent will depend on heart rhythm, co-morbid...
journal_title:European journal of heart failure
pub_type: 杂志文章,评审
doi:10.1093/eurjhf/hft129
更新日期:2014-01-01 00:00:00
abstract:AIMS:Pronounced trabeculation is presented in both left ventricular non-compaction (LVNC) and dilated cardiomyopathy (DCM), which sometimes makes the differentiation difficult. We hypothesized that echocardiographic deformation analysis would help to differentiate these two cardiomyopathies. METHODS AND RESULTS:We inv...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfr164
更新日期:2012-02-01 00:00:00
abstract:AIMS:We evaluated the applicability and prognostic importance of oral glucose tolerance testing (OGTT) among outpatients with systolic heart failure (SHF). METHODS AND RESULTS:Consecutive patients with SHF and left ventricular ejection fraction (LVEF) ≤ 45% referred to a heart failure clinic (n= 413) were included in ...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfq216
更新日期:2011-03-01 00:00:00
abstract:AIMS:We sought to test the utility of weight gain algorithms to predict episodes of worsening heart failure (WHF) using home-telemonitoring data collected as part of the TEN-HMS study. METHODS AND RESULTS:Simple rule-of-thumb (RoT) algorithms (i.e. 3 lbs in 1 day and 5 lbs in 3 days) and a moving average convergence d...
journal_title:European journal of heart failure
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurjhf/hfp033
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Hospital management of CHF and predictors of hospital mortality remain unclear. METHODS:To address these issues, we analyzed the hospital admissions for CHF during 1996 in a large university hospital. Patients discharged with the principal diagnosis of CHF were considered eligible for the study. RESULTS:Am...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/s1388-9842(01)00204-5
更新日期:2002-01-01 00:00:00
abstract:AIMS:The objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial oxygen saturation, increases respiratory rate and pulmonary artery pres...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hft003
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The angiotensin II type 2 (AT2) receptor is thought to play a role in cardiovascular disorders such as neointima formation after vascular injury, cardiac hypertrophy and myocardial infarction (MI). Recently, the biallelic polymorphism G + 1675A in intron 1 of the AT2 receptor gene has been associated with le...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/s1388-9842(02)00168-x
更新日期:2002-12-01 00:00:00
abstract:AIMS:Rho kinases (ROCKs) are the best characterized effectors of the small G-protein RhoA, and play a role in enhanced vasoconstriction in animal models of congestive heart failure (CHF). This study examined if ROCK activity is increased in CHF and how it is associated with the outcome in CHF. METHODS AND RESULTS:Pati...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfs068
更新日期:2012-09-01 00:00:00
abstract:AIMS:To determine the effects of a nurse-led intervention designed to improve self-management of patients with heart failure in a primary health care setting regarding health-related quality of life and depression. METHODS:Patients at eight primary health care centres were screened by the Diagnosis Related Groups regi...
journal_title:European journal of heart failure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ejheart.2004.01.016
更新日期:2005-03-16 00:00:00
abstract:BACKGROUND:Carvedilol is a beta-blocker with similar affinity for beta1- and beta2 receptors, while bisoprolol has higher beta1 affinity. The respiratory system is characterized by beta2-receptor prevalence. Airway beta receptors regulate bronchial tone and alveolar beta receptors regulate alveolar fluid re-absorption ...
journal_title:European journal of heart failure
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ejheart.2007.04.006
更新日期:2007-08-01 00:00:00
abstract:AIMS:To investigate the prognostic value of autonomic variables in patients with symptomatic chronic heart failure (HF) treated according to current recommendations. METHODS AND RESULTS:We analysed 24 h time-domain [standard deviation of all normal-to-normal RR intervals (SDNN)], frequency-domain [very low frequency a...
journal_title:European journal of heart failure
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurjhf/hfs126
更新日期:2012-12-01 00:00:00
abstract:AIMS:Remote patient management (telemonitoring) may help to detect early signs of cardiac decompensation, allowing optimization of and adherence to treatments in chronic heart failure (CHF). Two meta-analyses have suggested that telemedicine in CHF can reduce mortality by 30-35%. The aim of the TIM-HF study was to inve...
journal_title:European journal of heart failure
pub_type: 杂志文章,随机对照试验
doi:10.1093/eurjhf/hfq199
更新日期:2010-12-01 00:00:00
abstract::Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...
journal_title:European journal of heart failure
pub_type: 杂志文章,评审
doi:10.1016/j.ejheart.2008.06.015
更新日期:2008-09-01 00:00:00
abstract:AIMS:To evaluate right-ventricular (RV) function during stress echocardiography (SE) and to assess its relationship with exercise capacity in heart failure (HF) patients. METHODS AND RESULTS:We included 88 patients aged 60.9 +/- 11.2 years with a mean LVEF of 27.2 +/- 9.5%. The following RV parameters were measured at...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1093/eurjhf/hfp200
更新日期:2010-03-01 00:00:00
abstract::This article provides information and a commentary on trials presented at the American Heart Association meeting held in November 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports should be considered as preliminary data, as analyses may change in the final publication. In R...
journal_title:European journal of heart failure
pub_type: 杂志文章,评审
doi:10.1016/j.ejheart.2005.12.003
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:A low peak oxygen uptake (pVO(2)) and steep VE/VCO(2) slope are independently associated with a worse prognosis in patients with chronic heart failure (CHF). We wished to confirm whether combining these variables as a ratio would lead to a more accurate predictor of prognosis than using either alone. METHOD...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2007.10.010
更新日期:2008-01-01 00:00:00
abstract::Dilated cardiomyopathy (DCM) represents a particular aetiology of systolic heart failure that frequently has a genetic background and usually affects young patients with few co-morbidities. The prognosis of DCM has improved substantially during the last decades due to more accurate aetiological characterization, the r...
journal_title:European journal of heart failure
pub_type: 杂志文章,评审
doi:10.1002/ejhf.1103
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Plasma concentrations of atrial natriuretic peptides are correlated with atrial pressures, as are left ventricular ejection fraction and left ventricular filling abnormalities. AIMS:This study investigated the relation of atrial natriuretic peptides to both left ventricular systolic and diastolic function i...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/s1388-9842(98)00005-1
更新日期:1999-03-01 00:00:00
abstract:AIMS:Brain natriuretic peptide (BNP), NT-proBNP and troponins are useful for the assessment of patients with heart failure. Few data exist about their serial changes and their prognostic value in patients with acute heart failure (AHF). METHODS AND RESULTS:NT-proBNP and troponin-T plasma levels were measured at baseli...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2007.05.007
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Mechanical stress plays a crucial role in tissue morphogenesis and remodeling. These processes depend in part on force transmission mediated through integrins and the cytoskeleton. METHODS:Ventricular myocytes isolated from neonatal Sprague-Dawley rats (NRVMs) were exposed to persistent centrifugal force st...
journal_title:European journal of heart failure
pub_type: 杂志文章
doi:10.1016/j.ejheart.2005.05.014
更新日期:2006-01-01 00:00:00