Should travelers with hypertension adjust their medications when traveling to high altitude?

abstract：:Hypoxemia is usually associated with acute mountain sickness (AMS), but most studies have varied in time and magnitude of altitude exposure, exercise, diet, environmental conditions, and severity of pulmonary edema. We wished to determine whether hypoxemia occurred early in subjects who developed subsequent AMS while ...

journal_title：High altitude medicine & biology

authors： Loeppky JA,Icenogle MV,Charlton GA,Conn CA,Maes D,Riboni K,Gates L,Melo MF,Roach RC

更新日期：2008-01-01 00:00:00

abstract：:The purpose of high altitude continuing medical education is to adapt knowledge and skills for practical application on the plateau. Most trainees have experience with academic education and grassroots work experience on the plateau, so they want knowledge about new advances in the pathogenesis, diagnosis, and treatme...

journal_title：High altitude medicine & biology

authors： Luo Y,Zhou Q,Huang J,Luo R,Yang X,Gao Y

更新日期：2013-06-01 00:00:00

abstract：AIMS:Examined the change in neurobehavioral function of individuals acclimated to high altitudes and those native to high altitudes. METHODS:A neurobehavioral core test battery approved by the WHO (WHO-NCTB) was used to evaluate the effects of high altitude hypoxia on neurobehavioral function. The WHO-NCTB is composed...

journal_title：High altitude medicine & biology

authors： Zhang G,Zhou SM,Yuan C,Tian HJ,Li P,Gao YQ

更新日期：2013-12-01 00:00:00

abstract：:Bailey, Damian Miles, Benjamin S. Stacey, and Mark Gumbleton. A systematic review and meta-analysis reveals altered drug pharmacokinetics in humans during acute exposure to terrestrial high altitude-clinical justification for dose adjustment? High Alt Med Biol. 19:141-148, 2018. OBJECTIVE:While physiological response...

journal_title：High altitude medicine & biology

authors： Bailey DM,Stacey BS,Gumbleton M

更新日期：2018-06-01 00:00:00

abstract：:Appointing physiological function to specific genetic determinants requires a systems physiologist to consider ways of assessing precise phenotypic mechanisms. The integration of ventilation, metabolism and thermoregulation, for example, is very complex and may differ among small and large mammalian species. This chal...

journal_title：High altitude medicine & biology

authors： Soutiere SE,Tankersley CG

更新日期：2001-07-01 00:00:00

abstract：:Chronic mountain sickness (CMS) and high altitude pulmonary edema (HAPE) each occur rarely in Tibetans, and they have previously not been reported in the same person. Here we describe a 37-year-old native Tibetan man with CMS at 4300 m, who developed HAPE after his return home from a 12-day visit to sea level. Possibl...

journal_title：High altitude medicine & biology

authors： Wu T

更新日期：2004-07-01 00:00:00

abstract：:A 31-year-old man suffered diplopia and ataxia on two occasions when he ascended from sea level to 4,000 m. Evaluation revealed a moderate-sized subarachnoid cyst in the left frontal region, which did not communicate with the cerebral ventricles. The cyst might have acted as a space-occupying lesion, and caused sympto...

journal_title：High altitude medicine & biology

authors： Hackett PH

更新日期：2000-01-01 00:00:00

abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ

更新日期：2020-09-01 00:00:00

abstract：:Wagner, Dale R., Skyler Saunders, Brady Robertson, and John E. Davis. Normobaric hypoxia effects on balance measured by computerized dynamic posturography. High Alt Med Biol. 17:222-227, 2016.-Background/Aim: Equilibrium was measured by computerized dynamic posturography at varying levels of normobaric hypoxia before ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Saunders S,Robertson B,Davis JE

更新日期：2016-09-01 00:00:00

abstract：:Painschab, Matthew S., Gary E. Malpartida, Victor G. Davila-Roman, Robert H. Gilman, Todd M. Kolb, Fabiola Leon-Velarde, J. Jaime Miranda, and William Checkley. Association between serum concentrations of hypoxia inducible factor responsive proteins and excessive erythrocytosis in high altitude Peru. High Alt Med Biol...

journal_title：High altitude medicine & biology

authors： Painschab MS,Malpartida GE,Dávila-Roman VG,Gilman RH,Kolb TM,León-Velarde F,Miranda JJ,Checkley W

更新日期：2015-03-01 00:00:00

abstract：:Frequency of therapeutic beta-blocker use in elderly mountaineers is unknown. Therefore, the aim of this field study was to measure the regular beta-blocker intake in elderly persons visiting moderate altitudes. In a subset of mountaineers on beta-blockers, exercise response at two different altitude levels was compar...

journal_title：High altitude medicine & biology

authors： Faulhaber M,Flatz M,Burtscher M

更新日期：2003-01-01 00:00:00

abstract：AIMS:Published incidences of acute mountain sickness (AMS) vary widely. Reasons for this variation, and predictive factors of AMS, are not well understood. We aimed to identify predictive factors that are associated with the occurrence of AMS, and to test the hypothesis that study design is an independent predictive fa...

journal_title：High altitude medicine & biology

authors： Waeber B,Kayser B,Dumont L,Lysakowski C,Tramèr MR,Elia N

更新日期：2015-09-01 00:00:00

abstract：:Alpinist and scientist George Ingle Finch was invited on the 1921 British Mount Everest Reconnaissance, but events conspired to keep him away from Everest until the 1922 British expedition to the mountain. Very little is known in the English-speaking world about the 1925 German language book Der Kampf um den Everest, ...

journal_title：High altitude medicine & biology

authors： Rodway GW

更新日期：2007-04-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions. Hypoxia is a potent sympathetic stimulus that causes vasoconstriction of the peripheral blood vessels, which may further compound the risk of developing a cold-re...

journal_title：High altitude medicine & biology

authors： Jones D,Covins SF,Miller GE,Morrison KI,Clark AG,Calcott SD,Anderson AM,Lucas SJE,Imray CHE

更新日期：2018-12-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:Exposure to hypoxic environments is associated with decreased arterial oxygen saturation and increased pulmonary artery pressures. Ischemic preconditioning of an extremity (IPC) is a procedure that stimulates vasoactive and inflammatory pathways that protect remote organ systems from ongoing or future ischemic injury....

journal_title：High altitude medicine & biology

authors： Foster GP,Giri PC,Rogers DM,Larson SR,Anholm JD

更新日期：2014-06-01 00:00:00

abstract：UNLABELLED:Chronic hypoxia increases dependence on glucose in men and increases insulin sensitivity in men and women. Cyclic Variations in Altitude Conditioning (CVAC) is a novel technology that provides exposure to rapidly fluctuating cyclic hypobaric hypoxia (CHH). PURPOSE:To test the hypothesis that markers of gluc...

journal_title：High altitude medicine & biology

authors： Marquez JL,Rubinstein S,Fattor JA,Shah O,Hoffman AR,Friedlander AL

更新日期：2013-09-01 00:00:00

abstract：:The aim of the present study was to elucidate (1) the cardiovascular adaptations and response to hypoxic stimuli during short-term intermittent hypoxia and (2) whether the change in cardiovascular response to hypoxia is correlated to the change in hypoxic ventilatory chemosensitivity. Fourteen subjects were decompress...

journal_title：High altitude medicine & biology

authors： Katayama K,Shima N,Sato Y,Qiu JC,Ishida K,Mori S,Miyamura M

更新日期：2001-01-01 00:00:00

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- ...

journal_title：High altitude medicine & biology

authors： Bailey DM,Davies B,Milledge JS,Richards M,Williams SR,Jordinson M,Calam J

更新日期：2000-04-01 00:00:00

abstract：:Although thousands of people ascend 4205 m to visit the summit of Mauna Kea each year, there has been no information on the rate of altitude illness triggered by such visits. Two surveys were used: one for tourists driving up to the summit and the other for summit astronomy workers staying at lodging facilities at int...

journal_title：High altitude medicine & biology

authors： Onopa J,Haley A,Yeow ME

更新日期：2007-10-01 00:00:00

abstract：:In hypobaric hypoxia (HH) at high altitude, the immune responses are changed probably due to oxidative stress-induced production of free radicals and nonradicals. Vitamin E is an antioxidant and protects the cells from oxidative damage. The present study was carried out to study the antioxidant role of vitamin E on th...

journal_title：High altitude medicine & biology

authors： Goswami AR,Ghosh T

更新日期：2019-03-01 00:00:00

abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...

journal_title：High altitude medicine & biology

authors： Starling-Smith TM,La Monica MB,Stout JR,Fukuda DH

更新日期：2020-03-01 00:00:00

abstract：:The efficacy and safety of intermittent hypoxia training (IHT) were investigated in healthy, 60- to 74-yr-old men. Fourteen men (Gr 1) who routinely exercised daily for 20 to 30 min were compared with 21 (Gr 2) who avoided exercise. Their submaximal work-load power values before the IHT training were 94 +/- 3.7 and 66...

journal_title：High altitude medicine & biology

authors： Shatilo VB,Korkushko OV,Ischuk VA,Downey HF,Serebrovskaya TV

更新日期：2008-04-01 00:00:00

abstract：:Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks ove...

journal_title：High altitude medicine & biology

authors： Richalet JP,Lhuissier FJ

更新日期：2015-06-01 00:00:00

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00

abstract：:Hypoxemia is a major life-threatening complication of childhood pneumonia. The threshold points for hypoxemia vary with altitude. However, few published data describe that normal range of variation. The purpose of this study was to establish reference values of normal mean Sao(2) levels and an approximate cutoff point...

journal_title：High altitude medicine & biology

authors： Schult S,Canelo-Aybar C

更新日期：2011-04-01 00:00:00

abstract：:Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...

journal_title：High altitude medicine & biology

authors： Systermans B,Stokes S

更新日期：2019-12-01 00:00:00

abstract：:The phosphodiesterase-5 inhibitor sildenafil has been reported to improve hypoxic exercise capacity, but the mechanisms accounting for this observation remain incompletely understood. Sixteen healthy subjects were included in a randomized, double-blind, placebo-controlled, cross-over study on the effects of 50-mg sild...

journal_title：High altitude medicine & biology

authors： Faoro V,Lamotte M,Deboeck G,Pavelescu A,Huez S,Guenard H,Martinot JB,Naeije R

更新日期：2007-07-01 00:00:00