Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses.

abstract：:A preparation procedure for scanning electron microscopy was developed by which gononcoccal colonies can be studied directly on the agar surface. After glutaraldehyde fixation directly in petri dishes, small agar pieces were cut out and dehydrated stepwise in increasing concentrations of ethanol. The blocks were there...

journal_title：Infection and immunity

authors： Elmros T,Hörstedt P,Winblad B

更新日期：1975-09-01 00:00:00

abstract：:We compared a cryptococcal culture filtrate antigen referred to as CneF with chemically defined cryptococcal antigen fractions isolated by Cherniak and co-workers by using double immunodiffusion gels, polyacrylamide gel electrophoresis, immunoblots, and footpad reactivity of immunized mice. The three previously descri...

journal_title：Infection and immunity

authors： Murphy JW,Mosley RL,Cherniak R,Reyes GH,Kozel TR,Reiss E

更新日期：1988-02-01 00:00:00

abstract：:Archived sera (collected in 1946) from acute rheumatic fever (ARF) and untreated scarlet fever and/or pharyngitis patients were reacted with streptococcal M protein, cardiac myosin, and cardiac tropomyosin. Except for very low levels to tropomyosin, antibodies to other antigens were not elevated in the sera of ARF pat...

journal_title：Infection and immunity

authors： Jones KF,Whitehead SS,Cunningham MW,Fischetti VA

更新日期：2000-12-01 00:00:00

abstract：:Rabbit synovial cells (SC), articular chondrocytes (AC), and epiphyseal (EC) chondrocytes were grown in vitro. A portion of the spectrum of human pathogenic viruses infective for the cells was determined. Responses of the cells to different viruses or a chemical inducer of interferon varied, with EC responding vigorou...

journal_title：Infection and immunity

authors： Craig CP,Gordon SL,Greer RB

更新日期：1973-09-01 00:00:00

abstract：:Evidence is presented that the chronicity of infection in CBA mice after injection of Brucella abortus 19 is related to a number of factors: (i) the relative resistance of B. abortus to macrophage killing, which allowed some bacteria to survive the peak of macrophage activity occurring at 14 days; (ii) the decline in ...

journal_title：Infection and immunity

authors： Cheers C,Pagram F

更新日期：1979-02-01 00:00:00

abstract：:Exoantigens of Plasmodium vivax-parasitized erythrocytes stimulated macrophages to secrete tumor necrosis factor, and antisera raised against the exoantigens inhibited this secretion. The antisera also inhibited the activity of Plasmodium falciparum and Plasmodium yoelii exoantigens, and conversely, antisera against t...

journal_title：Infection and immunity

authors： Bate CA,Taverne J,Karunaweera ND,Mendis KN,Kwiatkowski D,Playfair JH

更新日期：1992-03-01 00:00:00

abstract：:Using pharmacologic and biochemical criteria, we evaluated whether uptake of four different Chlamydia trachomatis serovars, D, E, K, and L2, was dependent upon lipid rafts. Our data suggest that lipid raft-mediated entry is not required for C. trachomatis infection of cultured epithelial cells. ...

journal_title：Infection and immunity

authors： Gabel BR,Elwell C,van Ijzendoorn SC,Engel JN

更新日期：2004-12-01 00:00:00

abstract：:The ability of Streptococcus salivarius strain TOVE-R to inhibit the ecological emergence of virulent representatives of the most prevalent human mutans streptococci on the teeth of specific pathogen-free Osborne-Mendel rats was studied. Rats which were infected by TOVE-R, or either S. mutans 10449S or S. sobrinus 671...

journal_title：Infection and immunity

authors： Tanzer JM,Kurasz AB,Clive J

更新日期：1985-07-01 00:00:00

abstract：:Two weeks after mice had been infected in the footpad with cells of Nocardia brasiliensis, immunoglobulin and C3 deposits were observed in tissue from the inoculation site. Both immunoglobulin and C3 were found in the actinomycotic granules that characterize the mycetoma and in the surrounding inflammatory zones, in w...

journal_title：Infection and immunity

authors： Conde C,Mancilla R,Fresan M,Ortiz-Ortiz L

更新日期：1983-06-01 00:00:00

abstract：:Catheter-associated urinary tract infections (CAUTIs) constitute the majority of nosocomial UTIs and pose significant clinical challenges. Enterococcal species are among the predominant causative agents of CAUTIs. However, very little is known about the pathophysiology of Enterococcus-mediated UTIs. We optimized a mur...

journal_title：Infection and immunity

authors： Guiton PS,Hung CS,Hancock LE,Caparon MG,Hultgren SJ

更新日期：2010-10-01 00:00:00

abstract：:Helicobacter pylori mutants deficient in 6-phosphogluconate dehydratase (6PGD) were constructed. Colonization densities were lower and minimum infectious doses were higher for mutant strains than for wild-type strains. In spite of better colonization, however, wild-type strains did not displace the mutant in cocoloniz...

journal_title：Infection and immunity

authors： Wanken AE,Conway T,Eaton KA

更新日期：2003-05-01 00:00:00

abstract：:We investigated the effect of the extracellular protease of Serratia marcescens on human serum constituents such as immunoglobulins, fibronectin, alpha 1-protease inhibitor, alpha 2-macroglobulin, lysozyme, and transferrin. At a very low concentration of Serratia 56-kilodalton protease (56K protease), purified human p...

journal_title：Infection and immunity

authors： Molla A,Matsumoto K,Oyamada I,Katsuki T,Maeda H

更新日期：1986-09-01 00:00:00

abstract：:Glucan-binding protein B (GbpB) from Streptococcus mutans has been shown to induce protective immunity to dental caries in experimental models. Having recently sequenced the gbpB gene, our objective in this study was to identify immunogenic regions within the GbpB sequence for use in subunit vaccines. Potential region...

journal_title：Infection and immunity

authors： Smith DJ,King WF,Barnes LA,Peacock Z,Taubman MA

更新日期：2003-03-01 00:00:00

abstract：:Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacterial proteins. Gamma interferon (IFN-gamma) production by NK cells was seen in approximately 30% of noninfected calves in response to the Mycobacterium tube...

journal_title：Infection and immunity

authors： Olsen I,Boysen P,Kulberg S,Hope JC,Jungersen G,Storset AK

更新日期：2005-09-01 00:00:00

abstract：:We have discovered two distinctly different fimbriae expressed by the same Porphyromonas gingivalis strain. The construction of a fimA mutant of P. gingivalis ATCC 33277 has previously been reported by N. Hamada et al. (Infect. Immun. 62:1696-1704, 1994). Expression of fimbriae on the surface of the fimA mutant and th...

journal_title：Infection and immunity

authors： Hamada N,Sojar HT,Cho MI,Genco RJ

更新日期：1996-11-01 00:00:00

abstract：:The in vitro effects of pneumolysin, a sulfhydryl-activated toxin produced by Streptococcus pneumoniae, on various functions of human polymorphonuclear leukocytes (PMNLs) was investigated. Treatment of PMNLs with highly purified toxin significantly inhibited respiratory burst (in response to stimulation), ability to k...

journal_title：Infection and immunity

authors： Paton JC,Ferrante A

更新日期：1983-09-01 00:00:00

abstract：:The interaction of Borrelia burgdorferi, the causative agent of Lyme borreliosis, with phagocytic cells induces the activation of NF-kappaB and the expression of proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha). B. burgdorferi-induced TNF-alpha production is also dependent on the activation ...

journal_title：Infection and immunity

authors： Olson CM,Hedrick MN,Izadi H,Bates TC,Olivera ER,Anguita J

更新日期：2007-01-01 00:00:00

abstract：:The mechanisms by which Mycobacterium tuberculosis elicits disease are complex, involving a large repertoire of bacterial genes that are required for in vivo growth and survival. To identify such genes, we utilized a high-throughput microarray detection method to rapidly screen hundreds of unique, genotypically define...

journal_title：Infection and immunity

authors： Lamichhane G,Tyagi S,Bishai WR

更新日期：2005-04-01 00:00:00

abstract：:Oxygenated fatty acids, or oxylipins, play an essential role in physiological signaling and developmental processes in animals, plants, and fungi. Previous characterization of three Aspergillus fumigatus dioxygenases (PpoA, PpoB, and PpoC), similar in sequence to mammalian cyclooxygenases, showed that PpoA is responsi...

journal_title：Infection and immunity

authors： Dagenais TR,Chung D,Giles SS,Hull CM,Andes D,Keller NP

更新日期：2008-07-01 00:00:00

abstract：:Filarial infection is initiated by mosquito-derived third-stage larvae (L3) deposited on the skin that transit through the epidermis, which contains Langerhans cells (LC) and keratinocytes (KC), among other cells. This earliest interaction between L3 and the LC likely conditions the priming of the immune system to the...

journal_title：Infection and immunity

authors： Boyd A,Bennuru S,Wang Y,Sanprasert V,Law M,Chaussabel D,Nutman TB,Semnani RT

更新日期：2013-05-01 00:00:00

abstract：:Host-driven macrophage apoptosis contributes to innate immunity during bacterial infection. Neisseria meningitidis inhibits apoptosis in a variety of cells, but its impact on macrophage apoptosis is unknown. We demonstrate that N. meningitidis prevents macrophage apoptosis via genes encoding nitric oxide detoxificatio...

journal_title：Infection and immunity

authors： Tunbridge AJ,Stevanin TM,Lee M,Marriott HM,Moir JW,Read RC,Dockrell DH

更新日期：2006-01-01 00:00:00

abstract：:This longitudinal prospective study shows that antibodies to the N-terminal block 2 region of the Plasmodium falciparum merozoite surface protein 1 (MSP-1) are associated with protection against clinical malaria in an area of stable but seasonal malaria transmission of Ghana. Antibodies to the block 2 region of MSP-1 ...

journal_title：Infection and immunity

authors： Cavanagh DR,Dodoo D,Hviid L,Kurtzhals JA,Theander TG,Akanmori BD,Polley S,Conway DJ,Koram K,McBride JS

更新日期：2004-11-01 00:00:00

abstract：:Shiga toxin-producing Escherichia coli (STEC) strains are responsible for causing hemolytic-uremic syndrome (HUS), and systemic administration of Shiga toxin (Stx)-specific human monoclonal antibodies (HuMAbs) is considered a promising approach for prevention or treatment of the disease in children. The goal of the pr...

journal_title：Infection and immunity

authors： Sheoran AS,Chapman S,Singh P,Donohue-Rolfe A,Tzipori S

更新日期：2003-06-01 00:00:00

abstract：:Athymic nude mice (nu/nu), heterozygous litter mates (nu/+), and thymic reconstituted homozygous animals (nu/nu TxR) were infected with Trypanosoma rhodesiense. A reduced parasitemia and prolonged survival were observed in the nu/nu animals after infection and cure or after immunization with irradiated organisms. Thes...

journal_title：Infection and immunity

authors： Campbell GH,Esser KM,Phillips SM

更新日期：1978-06-01 00:00:00

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00

abstract：:The aroC gene of the facultative intracellular pathogen Brucella suis was cloned and sequenced. The cloned aroC gene complements Escherichia coli and Salmonella enterica serovar Typhimurium aroC mutants. A B. suis aroC mutant was found to be unable to grow in a defined medium without aromatic compounds. The mutant was...

journal_title：Infection and immunity

authors： Foulongne V,Walravens K,Bourg G,Boschiroli ML,Godfroid J,Ramuz M,O'Callaghan D

更新日期：2001-01-01 00:00:00

abstract：:Local passive immunization with monoclonal antibodies (Mc Ab) to Streptococcus mutans was attempted as an alternative approach to active systemic immunization. We prepared an immunoglobulin G class Mc Ab to the cell surface protein determinant of streptococcal antigen I/II and applied it repeatedly to the teeth of rhe...

journal_title：Infection and immunity

authors： Lehner T,Caldwell J,Smith R

更新日期：1985-12-01 00:00:00

abstract：:A large-scale DNA vaccination trial was performed with sheep to investigate whether an antigen targeted by CTLA-4 enhanced and accelerated the humoral immune response. Vaccination with genetically detoxified phospholipase D (DeltaPLD) has been shown to be effective, at least partially, against Corynebacterium pseudotu...

journal_title：Infection and immunity

authors： Chaplin PJ,De Rose R,Boyle JS,McWaters P,Kelly J,Tennent JM,Lew AM,Scheerlinck JP

更新日期：1999-12-01 00:00:00

abstract：:Targeting an antigen to Fc receptors (FcR) can enhance the immune response to the antigen in the absence of adjuvant. Furthermore, we recently demonstrated that intranasal immunization with an FcγR-targeted antigen enhances protection against a category A intracellular mucosal pathogen, Francisella tularensis. To dete...

journal_title：Infection and immunity

authors： Bitsaktsis C,Iglesias BV,Li Y,Colino J,Snapper CM,Hollingshead SK,Pham G,Gosselin DR,Gosselin EJ

更新日期：2012-03-01 00:00:00

abstract：:Immunoglobulin A (IgA) was prepared from samples of parotid saliva collected from two individuals over a 150-day period. Standardized solutions of the IgA were tested for agglutinating antibody activity against strains of streptococcus salivarius, S. sanguis, S. mitis, and S. mutans that had been isolated from a homol...

journal_title：Infection and immunity

authors： Bratthall D,Gibbons RJ

更新日期：1975-03-01 00:00:00