Abstract:
:We measured colonic effluent samples from 10 patients with colorectal cancer, 13 with adenomatous polyps, 14 with normal colons and compared them to 10 patients with inflammatory bowel disease by measuring this CA19-9 content. Results showed considerable overlap between the different pathologic categories, making differentiation impossible. A lower level of CA19-9 in the effluent samples from patients with adenomas was noted. These differences were reproducible for assays performed several months apart. CA19-9 may originate from the upper gastrointestinal tract since large amounts are present in pancreatico-biliary secretions. This antigen is therefore not useful in the diagnosis of neoplasia or inflammatory bowel disease using colonic effluent samples as the test material.
journal_name
Cancer Lettjournal_title
Cancer lettersauthors
Tobi M,Steinberg W,Henry J,Nochomovitz Ldoi
10.1016/0304-3835(91)90043-hsubject
Has Abstractpub_date
1991-10-01 00:00:00pages
9-13issue
1eissn
0304-3835issn
1872-7980pii
0304-3835(91)90043-Hjournal_volume
60pub_type
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