Phytohormone-based activity mapping of insect herbivore-produced elicitors.

abstract：:As an electron transfer-driven proton pump, cytochrome c oxidase (ferrocytochrome-c:oxygen oxidoreductase, EC 1.9.3.1) must alternate between two conformations in each valence state of the redox element associated with ion translocation. Using second derivative absorption spectroscopy, the conformation of the cytochro...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Copeland RA

更新日期：1991-08-15 00:00:00

abstract：:We present a theory, and its computer implementation, of how mental simulations underlie the abductions of informal algorithms and deductions from these algorithms. Three experiments tested the theory's predictions, using an environment of a single railway track and a siding. This environment is akin to a universal Tu...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Khemlani SS,Mackiewicz R,Bucciarelli M,Johnson-Laird PN

更新日期：2013-10-15 00:00:00

abstract：:Peroxisomes are eukaryotic organelles critical for plant and human development because they house essential metabolic functions, such as fatty acid β-oxidation. The interacting ATPases PEX1 and PEX6 contribute to peroxisome function by recycling PEX5, a cytosolic receptor needed to import proteins targeted to the pero...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gonzalez KL,Ratzel SE,Burks KH,Danan CH,Wages JM,Zolman BK,Bartel B

更新日期：2018-04-03 00:00:00

abstract：:Whole human blood was examined by (31)P nuclear magnetic resonance spectroscopy. Individual phosphates (alpha,beta,gamma) of ATP were identifiable, and two microenvironments appeared to be present for this molecule. When sequential recordings of freshly collected blood were made, 2,3-diphosphoglycerate was observed to...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Henderson TO,Costello AJ,Omachi A

更新日期：1974-06-01 00:00:00

abstract：:Linear growth delay (stunting) affects roughly 155 million children under the age of 5 years worldwide. Treatment has been limited by a lack of understanding of the underlying pathophysiological mechanisms. Stunting is most likely associated with changes in the microbial community of the small intestine, a compartment...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vonaesch P,Morien E,Andrianonimiadana L,Sanke H,Mbecko JR,Huus KE,Naharimanananirina T,Gondje BP,Nigatoloum SN,Vondo SS,Kaleb Kandou JE,Randremanana R,Rakotondrainipiana M,Mazel F,Djorie SG,Gody JC,Finlay BB,Rubbo PA,

更新日期：2018-09-04 00:00:00

abstract：:Despite the success statistical physics has enjoyed at predicting the properties of materials for given parameters, the inverse problem, identifying which material parameters produce given, desired properties, is only beginning to be addressed. Recently, several methods have emerged across disciplines that draw upon o...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Miskin MZ,Khaira G,de Pablo JJ,Jaeger HM

更新日期：2016-01-05 00:00:00

abstract：:To identify the binding domain for dihydropyridine Ca2+ antagonists, skeletal muscle Ca2+ channels were photolabeled with [3H](+)-PN200-110 and [3H]azidopine. Regions of alpha 1 photolabeled by these ligands were then identified by antibody mapping of proteolytic fragments. Approximately 50% of the specific labeling b...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Striessnig J,Murphy BJ,Catterall WA

更新日期：1991-12-01 00:00:00

abstract：:Unintended anthropogenic deposition of sulfur (S) to forest ecosystems has a range of negative consequences, identified through decades of research. There has been far less study of purposeful S use in agricultural systems around the world, including the application of elemental sulfur (S(0)) as a quick-reacting fungi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hinckley EL,Matson PA

更新日期：2011-08-23 00:00:00

abstract：:Influenza virus infections cause a wide variety of outcomes, from mild disease to 3 to 5 million cases of severe illness and ∼290,000 to 645,000 deaths annually worldwide. The molecular mechanisms underlying these disparate outcomes are currently unknown. Glycosylation within the human host plays a critical role in in...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Heindel DW,Koppolu S,Zhang Y,Kasper B,Meche L,Vaiana CA,Bissel SJ,Carter CE,Kelvin AA,Elaish M,Lopez-Orozco J,Zhang B,Zhou B,Chou TW,Lashua L,Hobman TC,Ross TM,Ghedin E,Mahal LK

更新日期：2020-10-27 00:00:00

abstract：:When purified dimers of hemagglutinin-neuraminidase molecules released by protease digestion from three strains of human parainfluenza virus 1 were used in crystallization trials, long thin needle crystals formed. Electron microscopic analysis of these needle crystals revealed that they are composed of stacks of tripl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Murti KG,Takimoto T,Laver WG,Portner A

更新日期：1993-02-15 00:00:00

abstract：:We give a functional generalization of fractal scaling laws applied to response problems as well as to probability distributions. We consider excitations and responses, which are functions of a given state vector. Based on scaling arguments, we derive a general nonlinear response functional scaling law, which expresse...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vlad MO,Morán F,Popa VT,Szedlacsek SE,Ross J

更新日期：2007-03-20 00:00:00

abstract：:Cholinergic neuromodulation is involved in all aspects of sensory processing and is crucial for processes such as attention, learning and memory, etc. However, despite the known roles of acetylcholine (ACh), we still do not how to disentangle ACh contributions from sensory or task-evoked changes in functional magnetic...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zaldivar D,Rauch A,Logothetis NK,Goense J

更新日期：2018-12-18 00:00:00

abstract：:Suppressor of variegation 3-9 homolog 1 (SUV39H1), a histone methyltransferase, catalyzes histone 3 lysine 9 trimethylation and is involved in heterochromatin organization and genome stability. However, the mechanism for regulation of the enzymatic activity of SUV39H1 in cancer cells is not yet well known. In this stu...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wang D,Zhou J,Liu X,Lu D,Shen C,Du Y,Wei FZ,Song B,Lu X,Yu Y,Wang L,Zhao Y,Wang H,Yang Y,Akiyama Y,Zhang H,Zhu WG

更新日期：2013-04-02 00:00:00

abstract：:Whereas 234(92)U142 and other actinon nuclei have ground-state bands that indicate that each nucleus consists of a sphere and a single revolving cluster with constant composition and with only a steady increase in the moment of inertia with increase in J, the angular-momentum quantum number, many of the lanthanon grou...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pauling L

更新日期：1991-02-01 00:00:00

abstract：:Threats to species from commercial fishing are rarely identified until species have suffered large population declines, by which time remedial actions can have severe economic consequences, such as closure of fisheries. Many of the species most threatened by fishing are caught in multispecies fisheries, which can rema...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Burgess MG,Polasky S,Tilman D

更新日期：2013-10-01 00:00:00

abstract：:Alterations in the activity/levels of the extralarge G protein α-subunit (XLαs) are implicated in various human disorders, such as perinatal growth retardation. Encoded by GNAS, XLαs is partly identical to the α-subunit of the stimulatory G protein (Gsα), but the cellular actions of XLαs remain poorly defined. Followi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： He Q,Bouley R,Liu Z,Wein MN,Zhu Y,Spatz JM,Wang CY,Divieti Pajevic P,Plagge A,Babitt JL,Bastepe M

更新日期：2017-11-07 00:00:00

abstract：:LMB-7 [B3(Fv)-PE38] is a single-chain immunotoxin constructed from the murine monoclonal antibody B3 and a truncated from of Pseudomonas exotoxin PE38. Antibody B3 recognizes a carbohydrate epitope found on solid tumors that frequently invade the intrathecal space and cause neoplastic meningitis. We tested the therape...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pastan IH,Archer GE,McLendon RE,Friedman HS,Fuchs HE,Wang QC,Pai LH,Herndon J,Bigner DD

更新日期：1995-03-28 00:00:00

abstract：:Ice-core records show that climate changes in the past have been large, rapid, and synchronous over broad areas extending into low latitudes, with less variability over historical times. These ice-core records come from high mountain glaciers and the polar regions, including small ice caps and the large ice sheets of ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Alley RB

更新日期：2000-02-15 00:00:00

abstract：:The amino acid sequences of a number of closely related proteins ("napin") isolated from Brassica napus were determined by mass spectrometry without prior separation into individual components. Some of these proteins correspond to those previously deduced (napA, BngNAP1, and gNa), chiefly from DNA sequences. Others we...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gehrig PM,Krzyzaniak A,Barciszewski J,Biemann K

更新日期：1996-04-16 00:00:00

abstract：:Many cellular cargoes move bidirectionally along microtubules, driven by teams of plus- and minus-end-directed motor proteins. To probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocytosed into living mammalian macrophages. These latex bead compartments (LBCs) are encased ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hendricks AG,Holzbaur EL,Goldman YE

更新日期：2012-11-06 00:00:00

abstract：:A panel of 20 recombinant Fab fragments reactive with the surface glycoprotein gp120 of human type 1 immunodeficiency virus (HIV-1) were examined for their ability to neutralize MN and IIIB strains of the virus. Neutralization was determined as the ability of the Fab fragments to inhibit infection as measured in both ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Barbas CF 3rd,Björling E,Chiodi F,Dunlop N,Cababa D,Jones TM,Zebedee SL,Persson MA,Nara PL,Norrby E

更新日期：1992-10-01 00:00:00

abstract：:Setting aside high-quality large areas of habitat to protect threatened populations is becoming increasingly difficult as humans fragment and degrade the environment. Biologists and managers therefore must determine the best way to shepherd small populations through the dual challenges of reductions in both the number...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hufbauer RA,Szűcs M,Kasyon E,Youngberg C,Koontz MJ,Richards C,Tuff T,Melbourne BA

更新日期：2015-08-18 00:00:00

abstract：:The genomic concentrations of certain middle repetitive DNA sequences vary considerably among closely related species of Drosophila. In fact, the chromosomes of D. melanogaster appear to carry approximately 3 times as much middle repetitive DNA as those of the sibling species D. simulans. Although most of the middle r...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dowsett AP,Young MW

更新日期：1982-08-01 00:00:00

abstract：:Myosins are molecular motors that power diverse cellular processes, such as rapid organelle transport, muscle contraction, and tension-sensitive anchoring. The structural adaptations in the motor that allow for this functional diversity are not known, due, in part, to the lack of high-resolution structures of highly t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shuman H,Greenberg MJ,Zwolak A,Lin T,Sindelar CV,Dominguez R,Ostap EM

更新日期：2014-02-11 00:00:00

abstract：:The three-dimensional structure of a human monoclonal antibody (Fab), which binds specifically to a major epitope of the transmembrane protein gp41 of the human immunodeficiency virus type 1, has been determined by crystallographic methods to a resolution of 2.7 A. It has been previously determined that this antibody ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： He XM,Rüker F,Casale E,Carter DC

更新日期：1992-08-01 00:00:00

abstract：:The progesterone receptor (PGR) is a ligand-activated transcription factor with key roles in the regulation of female fertility. Much has been learned of the actions of PGR signaling through the use of pharmacologic inhibitors and genetic manipulation, using mouse mutagenesis. Characterization of rats with a null muta...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kubota K,Cui W,Dhakal P,Wolfe MW,Rumi MA,Vivian JL,Roby KF,Soares MJ

更新日期：2016-04-12 00:00:00

abstract：:The triphenylmethane derivative aurintricarboxylic acid (ATA), but not aurin, selectively prevented the binding of OKT4A/Leu-3a monoclonal antibody (mAb) and, to a lesser extent, OKT4 mAb to the CD4 cell receptor for human immunodeficiency virus type 1 (HIV-1). The effect was seen within 1 min at an ATA concentration ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schols D,Baba M,Pauwels R,Desmyter J,De Clercq E

更新日期：1989-05-01 00:00:00

abstract：:The heat shock protein (Hsp)70 family of molecular chaperones interacts with unfolded proteins through a C-terminal substrate-binding domain (SBD) that is controlled by nucleotide binding to the N-terminal domain. The ATPase cycle is regulated by cochaperones, including DnaJ proteins that accelerate ATP hydrolysis to ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Awad W,Estrada I,Shen Y,Hendershot LM

更新日期：2008-01-29 00:00:00

abstract：:The effect of pH on the membrane-fusion activity of Sendai virus was examined (pH 5.0-9.5) by using, as assays of activity, hemolysis of chicken erythrocytes and the fusion of baby hamster kidney (BHK-21) cells. Exposure of virus to basic pH increased fusion activity; the optimum pH was found to be approximately equal...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hsu MC,Scheid A,Choppin PW

更新日期：1982-10-01 00:00:00

abstract：:A further study is made of the intertwining operators for the representations of the simple Lie groups of real rank one. We extend and apply this to the higher rank case, obtaining various results dealing with reducibility of principal series and existence of complementary series. ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Knapp AW,Stein EM

更新日期：1970-05-01 00:00:00