Abstract：
OBJECTIVE:To report two cases of early onset cholestasis of pregnancy associated with IVF and ovarian hyperstimulation syndrome. DESIGN:Case report. SETTING:University-based IVF program. PATIENT(S):Two patients with first-trimester cholestasis of pregnancy after IVF that was associated with ovarian hyperstimulation syndrome. INTERVENTION(S):In vitro fertilization-embryo transfer, management of hyperstimulation syndrome, and cholestasis of pregnancy. MAIN OUTCOME MEASURE(S):Clinical pregnancy course and pregnancy outcomes. RESULT(S):The first patient was treated with ursodeoxycholic acid and had resolution of symptoms within the first trimester. The second patient initially had a miscarriage but did redevelop cholestasis of pregnancy in the latter stages of a pregnancy resulting from frozen embryo transfer. CONCLUSION(S):We report two cases of intrahepatic cholestasis of pregnancy in the first trimester of pregnancies by IVF in association with ovarian hyperstimulation syndrome and markedly elevated maternal serum estrogen levels. Early recognition of this unusual clinical presentation allows for optimal pregnancy management by both the reproductive endocrinologist and the obstetrician.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Zamah AM,El-Sayed YY,Milki AAdoi
10.1016/j.fertnstert.2007.08.072subject
Has Abstractpub_date
2008-10-01 00:00:00pages
1202.e7-10issue
4eissn
0015-0282issn
1556-5653pii
S0015-0282(07)03468-1journal_volume
90pub_type
杂志文章abstract：OBJECTIVE:To review the association between autoimmunity and reproductive failure. DESIGN:A MEDLINE search done from 1965 to 1996. More than 300 original and review articles were evaluated, from which the most relevant were selected. RESULT(S):Autoimmune processes now are accepted widely as one of the possible mechan...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(97)81351-9
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVE:To study the reproductive and metabolic differences between daughters of women with polycystic ovary syndrome (PCOSd) and control women (Cd) after menarche. DESIGN:Case-control study. SETTING:Clinical endocrinology unit. PATIENT(S):We studied 43 PCOSd and 28 Cd 1.5-6 years after menarche. INTERVENTION(S):...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.10.011
更新日期：2019-02-01 00:00:00
abstract：:Six men, ages 18 to 34 years, with hypothalamic hypogonadotropism were treated with D-Trp6-luteinizing hormone-releasing hormone (10 micrograms intramuscularly on alternate days) for a period of 6 months. They underwent an intravenous luteinizing hormone-releasing hormone (LH-RH) test (50 micrograms/sq m) before and a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45381-1
更新日期：1981-03-01 00:00:00
abstract：:We studied 68 men with varicoceles to determine preoperative parameters that are associated with improvements in semen analysis after varicocelectomy. Ultrasound-measured venous diameter and reversal of flow were found to correlate with successful outcome. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.038
更新日期：2006-07-01 00:00:00
abstract：:A battery-powered, bipolar electrocoagulator has been specifically developed for sealing the cut ends of the divided vas at vasectomy. With a minimum of electric power, the electrocoagulator destroys only the mucosa and one or two muscle cell layers of the vas, which leads to optimal fibrosis of the cut ends. This ins...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To determine whether self-selected women with polycystic ovary syndrome (PCOS) are abnormal compared with a control population. DESIGN:Case-control. SETTING:Support group meeting organized and initiated by patients. PATIENT(S):Forty-five self-selected women with PCOS and 80 control women. INTERVENTION(S):...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03153-9
更新日期：2002-07-01 00:00:00
abstract：:Menopausal hormone therapy (HT) has complex biologic effects but continues to have an important clinical role in the management of vasomotor and other menopausal symptoms. The rational use of menopausal HT requires balancing the potential benefits and risks of treatment. Findings from the Women's Health Initiative (WH...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2014.02.043
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To define the mechanism(s) underlying an association between asthenozoospermia and elevated blood, seminal plasma, and testicular cadmium levels in infertile human males using a rat model of environmentally relevant cadmium exposures. SETTING:University medical center andrology research laboratory. ANIMAL(S...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.12.035
更新日期：2008-02-01 00:00:00
abstract：:A single injection of the luteinizing hormone (LH)-releasing hormone (LHRH) agonist [D-Ala6,des-Gly-NH2(10)]LHRH ethylamide to female rats on diestrus I produced a marked reduction in ovarian LH/human chorionic gonadotropin (hCG) and follicle-stimulating hormone (FSH) receptor levels, uterine weight, and plasma proges...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43524-7
更新日期：1978-09-01 00:00:00
abstract：:It is important to have an accurate model for calculating limits to sperm donation so as to avoid inadvertent half-sibling mating and help protect the rights and welfare of the donor- inseminated child. The most highly developed model to date cannot be used as there is inadequate regulation of donor insemination among...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.01.099
更新日期：2009-12-01 00:00:00
abstract：:Heterologous antibodies have frequently been used to develop assays in other species. Human urinary LH kits, widely available for predicting the LH surge, offer a unique opportunity to determine the timing of ovulation and mating in nonhuman primates. We tested three commercially available ovulation predictor kits for...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53301-9
更新日期：1990-02-01 00:00:00
abstract：OBJECTIVE:To determine if human luteinized granulosa cells (GCs) exhibit angiotensin II (AII) receptors and if AII affects GC steroidogenesis. DESIGN:Luteinized GCs were either treated immediately or maintained in culture for up to 6 days before use. The presence of functional AII receptors was evaluated using the fol...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55630-1
更新日期：1993-01-01 00:00:00
abstract：:Insulin-like growth factor I (IGF-I) has been proposed to be an autocrine/paracrine factor involved in granulosa cell proliferation and differentiation. The present study focuses on a possible mitogenic effect of IGF-I in human granulosa cells. Insulin-like growth factor I (1 to 10 ng/mL) significantly stimulated 3H-t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-12-01 00:00:00
abstract：:We wished to verify whether semen processing by discontinuous double-layered density gradient centrifugation could improve sperm apoptotic DNA fragmentation rates using a commercially available deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling assay in 35 consecutive men presenting for ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.01.059
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To identify the risk factors for ectopic pregnancy (EP) in women using an intrauterine device (IUD). DESIGN:Case-control study. SETTING:Auvergne region (France). PATIENT(S):Women using an IUD and suffering EP (243 cases) or having an intrauterine pregnancy (140 controls). INTERVENTION(S):None. MAIN OUTCO...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01605-8
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the occurrence of microdeletions of the Y chromosome involving the DAZ and YRRM genes in patients with Klinefelter's syndrome with and without spermatogenesis. DESIGN:Controlled clinical study. SETTING:Yamagata University Hospital, Yamagata, Japan. PATIENT(S):Patients with Klinefelter's syndrom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00546-9
更新日期：1999-04-01 00:00:00
abstract：:Disorders of development, fusion, or resorption of paired müllerian ducts and urogenital sinus may cause various congenital malformations of the corpus uteri, cervix, vagina, and fallopian tubes. Classification systems have been developed to better characterize these anomalies, and each has advantages and disadvantage...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2019.07.005
更新日期：2019-09-01 00:00:00
abstract：:Comparative studies have been carried out on the behavior of human and bovine spermatozoa toward homologous cervical mucus in vitro. In both cases the degree of sperm penetration and the pattern of sperm motility were influenced in a characteristic fashion by prior manipulation of the mucus: the most rapid and extensi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：OBJECTIVE:To study the chromosomal content of spermatozoa selected by intracytoplasmic morphologically selected sperm injection (IMSI) in cases of macrocephalic sperm head syndrome. DESIGN:Case report. SETTING:Obstetrics, gynecology, urology, and reproductive biology departments. PATIENT(S):Two infertile patients wi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.10.059
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:To investigate whether the insulin receptor substrate (IRS)-2 G1057D polymorphism is associated with the risk of endometriosis, and to evaluate potential correlation of IRS2 gene polymorphism with the stages of endometriosis. DESIGN:Case-control study. SETTING:Gynecology clinics in university hospital. PAT...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.09.023
更新日期：2010-10-01 00:00:00
abstract：:The gestational age and the serum human chorionic gonadotropin (hCG) at which an intrauterine pregnancy can be detected using transvaginal ultrasonography (TVU) is not known. In this study, ten pregnant women were serially scanned with TVU from the time of initial positive pregnancy test, to determine when an intraute...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59884-7
更新日期：1988-05-01 00:00:00
abstract：OBJECTIVE:To determine the relative efficacy of ultrasound-guided embryo transfer and embryo transfer by clinical touch alone. DESIGN:Systematic review and meta-analysis of randomized, controlled trials comparing ultrasound-guided embryo transfer with embryo transfer by clinical touch alone. SETTING:Infertility cente...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/s0015-0282(03)01015-x
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:To measure the level of distress and its relationship with other psychologic factors in women with diminished ovarian reserve (DOR) who participated in a fragile X genetics study. DESIGN:Longitudinal data analyzed with structural equation modeling. SETTING:Four U.S. private and academic fertility centers. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2013.02.033
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To correlate apoptosis of cultured human granulosa-lutein cells (GL cells) with the outcome of IVF (embryo fragmentation and pregnancy rate) and to study the effect of insulin and insulin-like growth factor I (IGF-I) on apoptosis. DESIGN:In vitro assays. SETTING:University laboratory and private IVF center....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.014
更新日期：2006-02-01 00:00:00
abstract：:This study was undertaken to determine whether women with endometriosis have altered protein, progesterone (P), and protease inhibitor concentrations in their uterine fluid and peritoneal fluid (PF) compared with controls at different phases of the menstrual cycle. Uterine flushings (UFs), PF, and blood were obtained ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)49994-2
更新日期：1987-02-01 00:00:00
abstract：OBJECTIVE:Report of a rare case of consecutive spontaneous cervical pregnancies. DESIGN:Case study. SETTING:Teaching hospital. PATIENT(S):One healthy nulliparous woman in the early years of her fourth decade. INTERVENTION(S):The first of two cervical pregnancies was treated with two doses of methotrexate and subseq...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.06.012
更新日期：2004-01-01 00:00:00
abstract：:Since the dominant follicle is selected by days 5 to 7 of the menstrual cycle, we assessed the differential effects of high-dose clomiphene (25 mg daily) by giving 5-day courses either before (days 1 to 5), during (days 5 to 9), or after (days 9 to 13) emergence of the selected dominant follicle in monkeys. Peripheral...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46403-4
更新日期：1982-07-01 00:00:00
abstract：OBJECTIVE:To identify and characterize a novel sperm motility-stimulating protein (MSP) from caprine serum. DESIGN:Prospective experimental study. SETTING:Research laboratory. ANIMAL(S):Rabbits and male and female BALB/c mice. INTERVENTION(S):Protein purification by conventional methods and functional and immunolog...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.03.012
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:To describe a live birth obtained in Italy after autologous orthotopic transplantation of cryopreserved ovarian cortical tissue. DESIGN:Case report. SETTING:University department of gynecology and obstetrics, reproductive medicine and IVF unit. PATIENT(S):A 29-year-old patient affected by β-thalassemia (in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.09.029
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the results of IVF in women > or = 40 years of age using their own oocytes. DESIGN:Retrospective study. SETTING:Wolfson and Royal Masonic in vitro fertilization units, London, United Kingdom. PATIENT(S):A total of 1,087 IVF cycles were started in women > or = 40 years of age. INTERVENTION(S):M...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00353-7
更新日期：1998-12-01 00:00:00
