Cytotoxicity of T-2 toxin and its metabolites determined with the neutral red cell viability assay.

Abstract:

:The neutral red (NR) cell viability assay was used with various cell types of human origin to quantitate the potency of T-2 mycotoxin and its metabolites. The human melanoma SK-Mel/27 cell line was the most sensitive, with a midpoint cytotoxicity value of 2.8 ng of T-2 per ml. With the human hepatoma cell line, HepG2, the sequence of potency for a series of mycotoxins was T-2 greater than HT-2 greater than T-2 triol greater than T-2 tetraol.

journal_name

Appl Environ Microbiol

authors

Babich H,Borenfreund E

doi

10.1128/AEM.57.7.2101-2103.1991

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

2101-3

issue

7

eissn

0099-2240

issn

1098-5336

journal_volume

57

pub_type

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