Concurrent genotyping of Helicobacter pylori virulence genes and human cytokine SNP sites using whole genome amplified DNA derived from minute amounts of gastric biopsy specimen DNA.

abstract：ERRATUM:Upon publication of the original article (1) it was highlighted by the authors that a grant awarded to support the research work of the study was missed in the acknowledgements. It should also be acknowledged that the grant titled "Genotyping and Molecular Epidemiological Characteristic of Bacillus anthracis in...

journal_title：BMC microbiology

authors： Li S,Ma Q,Chen H,Wang D,Liu Y,Wei X,You L,Yao G,Tian K,Tang G

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:Adenosine triphosphate (ATP) is used as an intracellular energy source by all living organisms. It plays a central role in the respiration and metabolism, and is the most important energy supplier in many enzymatic reactions. Its critical role as the energy storage molecule makes it extremely valuable to all...

journal_title：BMC microbiology

authors： Mempin R,Tran H,Chen C,Gong H,Kim Ho K,Lu S

更新日期：2013-12-24 00:00:00

abstract：BACKGROUND:Non-structural protein 1 (NS1) is a multifunctional protein and a crucial regulatory factor in the replication and pathogenesis of avian influenza virus (AIV). Studies have shown that NS1 can interact with a variety of host proteins to modulate the viral life cycle. We previously generated a monoclonal antib...

journal_title：BMC microbiology

authors： Ma Y,Sun J,Gu L,Bao H,Zhao Y,Shi L,Yao W,Tian G,Wang X,Chen H

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:The aim of this study was to identify mutations of rpoB, katG, inhA and ahp-genes associated Mycobacterium tuberculosis resistance to rifampicin (RIF) and isoniazid (INH) in Kyrgyz Republic. We studied 633 smear samples from the primary pulmonary tuberculosis (TB) patients. We verified Mycobacterium tubercul...

journal_title：BMC microbiology

authors： Isakova J,Sovkhozova N,Vinnikov D,Goncharova Z,Talaibekova E,Aldasheva N,Aldashev A

更新日期：2018-03-22 00:00:00

abstract：BACKGROUND:Rhodobacter sphaeroides 2.4.1 is a metabolically versatile organism that belongs to α-3 subdivision of Proteobacteria. The present study was to identify the extent, history, and role of gene duplications in R. sphaeroides 2.4.1, an organism that possesses two chromosomes. RESULTS:A protein similarity search...

journal_title：BMC microbiology

authors： Bavishi A,Lin L,Schroeder K,Peters A,Cho H,Choudhary M

更新日期：2010-12-30 00:00:00

abstract：BACKGROUND:Since bacteria embedded in biofilms are far more difficult to eradicate than planktonic infections, it would be useful to know whether certain Staphylococcus aureus lineages are especially involved in strong biofilm formation. For this reason, in vitro biofilm formation of 228 clinical S. aureus isolates of ...

journal_title：BMC microbiology

authors： Croes S,Deurenberg RH,Boumans ML,Beisser PS,Neef C,Stobberingh EE

更新日期：2009-10-28 00:00:00

abstract：BACKGROUND:Pectobacterium carotovorum subsp. carotovorum is a phytopathogenic enterobacterium responsible for soft rot, a disease characterized by extensive maceration of the affected plant tissue. This species also produces two or more antibacterial substances called bacteriocins, which enhance its competitiveness aga...

journal_title：BMC microbiology

authors： Chan YC,Wu HP,Chuang DY

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:Microbial biofilms are known to cause an increasing number of chronic inflammatory and infectious conditions. A classical example is chronic periodontal disease, a condition initiated by the subgingival dental plaque biofilm on gingival epithelial tissues. We describe here a new model that permits the examin...

journal_title：BMC microbiology

authors： Guggenheim B,Gmür R,Galicia JC,Stathopoulou PG,Benakanakere MR,Meier A,Thurnheer T,Kinane DF

更新日期：2009-12-31 00:00:00

abstract：BACKGROUND:Listeria monocytogenes has been implicated in several food borne outbreaks as well as sporadic cases of disease. Increased understanding of the biology of this organism is important in the prevention of food borne listeriosis. The infectivity of Listeria monocytogenes ScottA, cultivated with and without oxyg...

journal_title：BMC microbiology

authors： Bo Andersen J,Roldgaard BB,Christensen BB,Licht TR

更新日期：2007-06-14 00:00:00

abstract：BACKGROUND:Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities for causing disseminated disease in the blood of C3H/HeJ mice during early infection. RESULTS:B...

journal_title：BMC microbiology

authors： Petzke MM,Iyer R,Love AC,Spieler Z,Brooks A,Schwartz I

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:The plasma membrane plays an essential role in selective permeability, compartmentalization, osmotic balance, and cellular uptake. The characteristics and functions of cyanobacterial membranes have been extensively investigated in recent years. Cell-penetrating peptides (CPPs) are special nanocarriers that c...

journal_title：BMC microbiology

authors： Liu BR,Huang YW,Lee HJ

更新日期：2013-03-14 00:00:00

abstract：BACKGROUND:Nucleotide sugar transporters (NSTs) play an essential role in translocating nucleotide sugars into the lumen of the endoplasmic reticulum and Golgi apparatus to be used as substrates in glycosylation reactions. This intracellular transport is an essential step in the biosynthesis of glycoconjugates. RESULT...

journal_title：BMC microbiology

authors： Baptista CG,Rodrigues EC,Morking P,Klinke A,Zardo ML,Soares MJ,de Aguiar AM,Goldenberg S,Ramos AS

更新日期：2015-11-21 00:00:00

abstract：BACKGROUND:Pyruvate oxidase (Pox) is an important enzyme in bacterial metabolism for increasing ATP production and providing a fitness advantage via hydrogen peroxide production. However, few Pox enzymes have been characterized from bacterial species. The tetrameric non-hydrogen-peroxide producing Pox from E. coli is a...

journal_title：BMC microbiology

authors： Cornacchione LP,Hu LT

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation. In this study, we used a high-throughput pyrosequencing approach to sequence the transcriptome of S. meliloti, and search for new bacterial genes missed in the previous ...

journal_title：BMC microbiology

authors： Mao C,Evans C,Jensen RV,Sobral BW

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:Chlamydiae are obligate intracellular pathogens that possess a type III secretion system to deliver proteins into the host cell during infection. Small molecule inhibitors of type III secretion in Yersinia, termed INPs (Innate Pharmaceuticals AB) were reported to strongly inhibit Chlamydia growth in epitheli...

journal_title：BMC microbiology

authors： Muschiol S,Normark S,Henriques-Normark B,Subtil A

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:Since 1994, Brucella strains have been isolated from a wide range of marine mammals. They are currently recognized as two new Brucella species, B. pinnipedialis for the pinniped isolates and B. ceti for the cetacean isolates in agreement with host preference and specific phenotypic and molecular markers. In ...

journal_title：BMC microbiology

authors： Maquart M,Le Flèche P,Foster G,Tryland M,Ramisse F,Djønne B,Al Dahouk S,Jacques I,Neubauer H,Walravens K,Godfroid J,Cloeckaert A,Vergnaud G

更新日期：2009-07-20 00:00:00

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:Iron is an essential nutrient but can be toxic at high intracellular concentrations and organisms have evolved tightly regulated mechanisms for iron uptake and homeostasis. Information on iron management mechanisms is available for organisms living at circumneutral pH. However, very little is known about how...

journal_title：BMC microbiology

authors： Osorio H,Martínez V,Nieto PA,Holmes DS,Quatrini R

更新日期：2008-11-24 00:00:00

abstract：BACKGROUND:Vibrio parahaemolyticus is a food-borne pathogen causing inflammation of the gastrointestinal epithelium. Pathogenic strains of this bacterium possess two Type III Secretion Systems (TTSS) that deliver effector proteins into host cells. In order to better understand human host cell responses to V. parahaemol...

journal_title：BMC microbiology

authors： Matlawska-Wasowska K,Finn R,Mustel A,O'Byrne CP,Baird AW,Coffey ET,Boyd A

更新日期：2010-12-30 00:00:00

abstract：BACKGROUND:Escherichia coli strains are commonly found in the gut microflora of warm-blooded animals. These strains can be assigned to one of the four main phylogenetic groups, A, B1, B2 and D, which can be divided into seven subgroups (A0, A1, B1, B22, B23, D1 and D2), according to the combination of the three genetic...

journal_title：BMC microbiology

authors： Carlos C,Pires MM,Stoppe NC,Hachich EM,Sato MI,Gomes TA,Amaral LA,Ottoboni LM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA's virulence and resistance mechanisms is a continuing concern toward controlling such burdens through using high throughput whole Genome Sequencing (WGS) and molecular diagnost...

journal_title：BMC microbiology

authors： Ali MS,Isa NM,Abedelrhman FM,Alyas TB,Mohammed SE,Ahmed AE,Ahmed ZSA,Lau NS,Garbi MI,Amirul AA,Seed AO,Omer RA,Mohamed SB

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Most group A streptococcal (GAS) vaccine strategies have focused on the surface M protein, a major virulence factor of GAS. The amino-terminus of the M protein elicits antibodies, that are both opsonic and protective, but which are type specific. J14, a chimeric peptide that contains 14 amino acids from the ...

journal_title：BMC microbiology

authors： Yoonim N,Olive C,Pruksachatkunakorn C,Pruksakorn S

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae has previously been characterized as a micro-organism that is genetically highly stable. In spite of this genetic stability, homologous DNA recombination has been hypothesized to lie at the basis of antigenic variation of the major surface protein, P1, of M. pneumoniae. In order to iden...

journal_title：BMC microbiology

authors： Sluijter M,Hoogenboezem T,Hartwig NG,Vink C

更新日期：2008-10-02 00:00:00

abstract：BACKGROUND:Non typhoidal salmonellosis is one of the neglected zoonoses in most African countries. The use of sub-therapeutic doses of antibiotics as animal growth promoter enhances the emergence and dissemination of antimicrobial resistance in bacteria with food animal reservoirs and may also results in antibiotics re...

journal_title：BMC microbiology

authors： Adetoye A,Pinloche E,Adeniyi BA,Ayeni FA

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:Successful viral infection requires the involvement of host cellular factors in their life cycle. Heat shock protein 70 (HSP70) can be recruited by numerous viruses to promote the folding, maturation, or assembly of viral proteins. We have previously shown that HSP70 is significantly elevated in porcine repr...

journal_title：BMC microbiology

authors： Gao J,Xiao S,Liu X,Wang L,Ji Q,Mo D,Chen Y

更新日期：2014-03-13 00:00:00

abstract：BACKGROUND:The heme acquisition machinery in Streptococcus pyogenes is believed to consist of the surface proteins, Shr and Shp, and heme-specific ATP-binding cassette transporter HtsABC. Shp has been shown to rapidly transfer its heme to the lipoprotein component, HtsA, of HtsABC. The function of Shr and the heme sour...

journal_title：BMC microbiology

authors： Zhu H,Liu M,Lei B

更新日期：2008-01-23 00:00:00

abstract：BACKGROUND:The mce operons play an important role in the entry of M. tuberculosis into macrophages and non-phagocytic cells. Their non-redundant function as well as complex regulation is implied by the phenotype of mce mutants. Recently, mce1 operon was found to extend over 13 genes, fadD5 (Rv0166) being the first gene...

journal_title：BMC microbiology

authors： Joon M,Bhatia S,Pasricha R,Bose M,Brahmachari V

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:The Bacillus anthracis S-layer protein, BslA, plays a crucial role in mammalian infection. BslA is required to mediate adherence between host cells and vegetative forms of bacteria and this interaction promotes target organs adherence and blood-brain barrier (BBB) penetration in vivo. This study attempts to ...

journal_title：BMC microbiology

authors： Wang Y,Wei Y,Yuan S,Tao H,Dong J,Zhang Z,Tian W,Liu C

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:Rhodosporidium toruloides is a β-carotenoid accumulating, oleaginous yeast that has great biotechnological potential. The lack of reliable and efficient genetic manipulation tools have been a major hurdle blocking its adoption as a biotechnology platform. RESULTS:We report for the first time the development...

journal_title：BMC microbiology

authors： Koh CM,Liu Y,Moehninsi,Du M,Ji L

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:The gut comprises an essential barrier that protects both invertebrate and vertebrate animals from invasion by microorganisms. Disruption of the balanced relationship between indigenous gut microbiota and their host can result in gut bacteria eliciting host responses similar to those caused by invasive patho...

journal_title：BMC microbiology

authors： Broderick NA,Raffa KF,Handelsman J

更新日期：2010-04-27 00:00:00