Inhibition of HSP70 reduces porcine reproductive and respiratory syndrome virus replication in vitro.

abstract：BACKGROUND:Microbiome and metagenomic studies have given rise to a new understanding of microbial colonization of various human tissues and their ability to impact our health. One human microbiome growing in notoriety, the vaginal microbiome, stands out given its importance for women's health, and is peculiar in terms ...

journal_title：BMC microbiology

authors： Brandt K,Barrangou R

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:Multi-locus sequence typing (MLST) is a portable, broadly applicable method for classifying bacterial isolates at an intra-species level. This methodology provides clinical and scientific investigators with a standardized means of monitoring evolution within bacterial populations. MLST uses the DNA sequences...

journal_title：BMC microbiology

authors： Adamiak P,Vanderkooi OG,Kellner JD,Schryvers AB,Bettinger JA,Alcantara J

更新日期：2014-06-03 00:00:00

abstract：BACKGROUND:Non-typeable Haemophilus influenzae biofilm formation is implicated in a number of chronic infections including otitis media, sinusitis and bronchitis. Biofilm structure includes cells and secreted extracellular matrix that is "slimy" and believed to contribute to the antibiotic resistant properties of biofi...

journal_title：BMC microbiology

authors： Gallaher TK,Wu S,Webster P,Aguilera R

更新日期：2006-07-19 00:00:00

abstract：BACKGROUND:Cysteine has a crucial role in cellular physiology and its synthesis is tightly controlled due to its reactivity. However, little is known about the sulfur metabolism and its regulation in clostridia compared with other firmicutes. In Clostridium perfringens, the two-component system, VirR/VirS, controls the...

journal_title：BMC microbiology

authors： André G,Haudecoeur E,Monot M,Ohtani K,Shimizu T,Dupuy B,Martin-Verstraete I

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:There is a rapid emergence of multiple resistant gram-negative bacteria due to overuse of antibiotics in the treatment of infections. Biofilms consist of polymicrobial communities that survive the host's defense system. The key bacteria in biofilms are slow growing and support an attachment and rapid growth ...

journal_title：BMC microbiology

authors： Wu C,Nakka S,Mansouri S,Bengtsson T,Nayeri T,Nayeri F

更新日期：2016-09-09 00:00:00

abstract：BACKGROUND:It is known that insects and crustaceans can carry simultaneous, active infections of two or more viruses without showing signs of disease, but it was not clear whether co-infecting viruses occupied the same cells or different cells in common target tissues. Our previous work showed that successive challenge...

journal_title：BMC microbiology

authors： Kanthong N,Khemnu N,Pattanakitsakul SN,Malasit P,Flegel TW

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:Streptococcus agalactiae (GBS) is a common pathogen to infect newborn, woman, the elderly, and immuno-compromised human and fish. 37 fish isolates and 554 human isolates of the GBS in 2007-2012 were investigated in serotypes, antibiotic susceptibility, genetic difference and pathogenicity to tilapia. RESULT...

journal_title：BMC microbiology

authors： Chu C,Huang PY,Chen HM,Wang YH,Tsai IA,Lu CC,Chen CC

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Pyruvate oxidase (Pox) is an important enzyme in bacterial metabolism for increasing ATP production and providing a fitness advantage via hydrogen peroxide production. However, few Pox enzymes have been characterized from bacterial species. The tetrameric non-hydrogen-peroxide producing Pox from E. coli is a...

journal_title：BMC microbiology

authors： Cornacchione LP,Hu LT

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:Mosquitoes are intermediate hosts for numerous disease causing organisms. Vector control is one of the most investigated strategy for the suppression of mosquito-borne diseases. Anopheles stephensi is one of the vectors of malaria parasite Plasmodium vivax. The parasite undergoes major developmental and matu...

journal_title：BMC microbiology

authors： Rani A,Sharma A,Rajagopal R,Adak T,Bhatnagar RK

更新日期：2009-05-19 00:00:00

abstract：BACKGROUND:The KdpD/KdpE two-component system of Escherichia coli regulates expression of the kdpFABC operon encoding the high affinity K+ transport system KdpFABC. The input domain of KdpD comprises a domain that belongs to the family of universal stress proteins (Usp). It has been previously demonstrated that UspC bi...

journal_title：BMC microbiology

authors： Heermann R,Lippert ML,Jung K

更新日期：2009-07-09 00:00:00

abstract：BACKGROUND:Staphylococcus aureus (S. aureus) is one of the primary causes of bone infections which are often chronic and difficult to eradicate. Bacteria like S. aureus may survive upon internalization in cells and may be responsible for chronic and recurrent infections. In this study, we compared the responses of a ph...

journal_title：BMC microbiology

authors： Hamza T,Li B

更新日期：2014-07-25 00:00:00

abstract：BACKGROUND:The dspA (hik33) gene, coding for a putative sensory histidine kinase, is conserved in plastids (ycf26) and cyanobacteria. It has been linked with a number of different stress responses in cyanobacteria. RESULTS:We constructed an insertional mutant of dspA (ycf26) in Synechocystis 6803. We found little phen...

journal_title：BMC microbiology

authors： Morrison SS,Mullineaux CW,Ashby MK

更新日期：2005-08-02 00:00:00

abstract：BACKGROUND:Over the last years oleaginous yeasts have been studied for several energetic, oleochemical, medical and pharmaceutical purposes. However, only a small number of yeasts are known and have been deeply exploited. The search for new isolates with high oleaginous capacity becomes imperative, as well as the use o...

journal_title：BMC microbiology

authors： Miranda C,Bettencourt S,Pozdniakova T,Pereira J,Sampaio P,Franco-Duarte R,Pais C

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:H-NS is a DNA-binding protein with central roles in gene regulation and nucleoid structuring in Escherichia coli. There are over 60 genes that are influenced by H-NS many of which are involved in metabolism. To determine the significance of H-NS-regulated genes in metabolism and stress tolerance, an hns muta...

journal_title：BMC microbiology

authors： Erol I,Jeong KC,Baumler DJ,Vykhodets B,Choi SH,Kaspar CW

更新日期：2006-08-15 00:00:00

abstract：BACKGROUND:Changes in aboveground plant species diversity as well as variations of environmental conditions such as exposure of ecosystems to elevated concentrations of atmospheric carbon dioxide may lead to changes in metabolic activity, composition and diversity of belowground microbial communities, both bacterial an...

journal_title：BMC microbiology

authors： Grüter D,Schmid B,Brandl H

更新日期：2006-07-27 00:00:00

abstract：BACKGROUND:Biofilm is a fundamental bacterial survival mode which proceeds through three main generalized phases: adhesion, maturation, and dispersion. Lactobacilli spp. (LB) are critical components of gut and reproductive health and are widely used probiotics. Evaluation of time-dependent mechanisms of biofilm formati...

journal_title：BMC microbiology

authors： Martinez S,Garcia JG,Williams R,Elmassry M,West A,Hamood A,Hurtado D,Gudenkauf B,Ventolini G,Schlabritz-Loutsevitch N

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Polymicrobial infections are responsible for significant mortality and morbidity in adults and children. Staphylococcus epidermidis and Candida albicans are the most frequent combination of organisms isolated from polymicrobial infections. Vascular indwelling catheters are sites for mixed species biofilm for...

journal_title：BMC microbiology

authors： Pammi M,Liang R,Hicks J,Mistretta TA,Versalovic J

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:Streptococcus suis is a major swine pathogen worldwide that causes meningitis, septicemia, arthritis, and endocarditis. Using animal models, a surface-associated subtilisin-like protease (SspA) has recently been shown to be an important virulence factor for S. suis. In this study, we hypothesized that the S....

journal_title：BMC microbiology

authors： Bonifait L,Grenier D

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The balanced synthesis of membrane phospholipids, fatty acids and cell wall constituents is a vital facet of bacterial physiology, but there is little known about the biochemical control points that coordinate these activities in Gram-positive bacteria. In Escherichia coli, the glycerol-phosphate acyltransfe...

journal_title：BMC microbiology

authors： Parsons JB,Yao J,Jackson P,Frank M,Rock CO

更新日期：2013-11-16 00:00:00

abstract：BACKGROUND:Modifiable lifestyle factors (e.g. dietary intake and physical activity) are important contributors to weight gain during college. The purpose of this study was to evaluate whether associations exist between body mass index, physical activity, screen time, dietary consumption (fat, protein, carbohydrates, an...

journal_title：BMC microbiology

authors： Whisner CM,Maldonado J,Dente B,Krajmalnik-Brown R,Bruening M

更新日期：2018-12-12 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein and nonstructural protein 4B (NS4B) are potentially oncogenic. Aberrant activation of the Wnt/β-catenin signaling pathway is closely associated with hepatocarcinogenesis. We investigated the effects of HCV type 1b core protein and NS4B on Wnt/β-catenin signaling in variou...

journal_title：BMC microbiology

authors： Jiang XH,Xie YT,Cai YP,Ren J,Ma T

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:The last step in the maturation process of the large subunit of [NiFe]-hydrogenases is a proteolytic cleavage of the C-terminal by a hydrogenase specific protease. Contrary to other accessory proteins these hydrogenase proteases are believed to be specific whereby one type of hydrogenases specific protease o...

journal_title：BMC microbiology

authors： Devine E,Holmqvist M,Stensjö K,Lindblad P

更新日期：2009-03-11 00:00:00

abstract：BACKGROUND:The increasing availability of whole genome sequences allows the gene or protein content of different organisms to be compared, leading to burgeoning interest in the relatively new subfield of pan-genomics. However, while several studies have analyzed protein content relationships in specific groups of bacte...

journal_title：BMC microbiology

authors： Trost B,Haakensen M,Pittet V,Ziola B,Kusalik A

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Next-generation sequencing platforms have revolutionised our ability to investigate the microbiota composition of complex environments, frequently through 16S rRNA gene sequencing of the bacterial component of the community. Numerous factors, including DNA extraction method, primer sequences and sequencing p...

journal_title：BMC microbiology

authors： Fouhy F,Clooney AG,Stanton C,Claesson MJ,Cotter PD

更新日期：2016-06-24 00:00:00

abstract：BACKGROUND:The genus Lactobacillus belongs to a large heterogeneous group of low G + C Gram-positive anaerobic bacteria, which are frequently used as probiotics. The health-beneficial effects, in particular the immunomodulation effect, of probiotics depend on the strain and dose used. Strain variations may be related t...

journal_title：BMC microbiology

authors： Górska S,Buda B,Brzozowska E,Schwarzer M,Srutkova D,Kozakova H,Gamian A

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:Recent studies have identified in Mycobacterium avium subsp. paratuberculosis (MAP), already known as a pathogen in ruminants, a potential zoonotic agent of some autoimmune diseases in humans. Therefore, considering the possible risk for public health, it is necessary a thorough understanding of MAP's gene e...

journal_title：BMC microbiology

authors： Cossu A,Sechi LA,Zanetti S,Rosu V

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Epidemiology of celiac disease (CD) is increasing. CD mainly presents in early childhood with small intestinal villous atrophy and signs of malabsorption. Compared to healthy individuals, CD patients seemed to be characterized by higher numbers of Gram-negative bacteria and lower numbers Gram-positive bacter...

journal_title：BMC microbiology

authors： Di Cagno R,De Angelis M,De Pasquale I,Ndagijimana M,Vernocchi P,Ricciuti P,Gagliardi F,Laghi L,Crecchio C,Guerzoni ME,Gobbetti M,Francavilla R

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:Candida albicans yeast produces 10 distinct secreted aspartic proteases (Saps), which are some of the most important virulence factors of this pathogenic fungus. One of the suggested roles of Saps is their deregulating effect on various proteolytic cascades that constitute the major homeostatic systems in hu...

journal_title：BMC microbiology

authors： Kozik A,Gogol M,Bochenska O,Karkowska-Kuleta J,Wolak N,Kamysz W,Aoki W,Ueda M,Faussner A,Rapala-Kozik M

更新日期：2015-03-04 00:00:00

abstract：BACKGROUND:Identification and characterization of intervening sequences (IVSs) within 23S rRNA genes from Campylobacter organisms including atypical campylobacters were carried out using two PCR primer pairs, designed to generate helix 25 and 45 regions. RESULTS:Only C. sputorum biovar sputorum LMG7975 and fecalis LMG...

journal_title：BMC microbiology

authors： Tazumi A,Kakinuma Y,Misawa N,Moore JE,Millar BC,Matsuda M

更新日期：2009-12-11 00:00:00

abstract：BACKGROUND:Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined changes in the gene expression profile of the C. neoformans reference strain H99 (serotype A) fol...

journal_title：BMC microbiology

authors： Florio AR,Ferrari S,De Carolis E,Torelli R,Fadda G,Sanguinetti M,Sanglard D,Posteraro B

更新日期：2011-05-11 00:00:00