Abstract:
OBJECTIVE:To study the etiological profile of patients with acute febrile encephalopathy syndrome focusing chiefly on the viral etiology, and to correlate clinical and radiological features of patients with viral encephalitis. METHODS:A prospective hospital based study conducted on the consecutive patients admitted in a pediatric unit during the period of 1(st) February 2004 to 31st January 2005 based on the following inclusion criteria: (1) Age more than 1 month and less than 18 years and (2) A diagnoses of acute febrile encephalopathy, based on the following criteria: (i) fever (ii) acute depression of consciousness or mental deterioration for more than 12 hours with or without motor or sensory deficit and (iii) Total duration of illness at the time of admission 1 week or less. RESULTS:The final study group comprised of 151 patients with mean age of 3.21 +/- 2.9 (range of mth-13 years) and male: female ratio of 1.71: 1. A diagnosis other than viral encephalitis was reached in 94 patients (62.3 %). Pyogenic meningitis was the most frequent diagnosis 51(33.8 %) followed by tubercular meningitis 12 (7.9 %), and cerebral malaria 8 (5.2 %) in the patient group of non-viral causes. Fifty-seven cases (37.3%) were suspected as viral encephalitis and mean age of the cases suspected as viral encephalitis was 2.8 +/- 2.9 (Range 1 mth-10 yrs) with male: female ratio of 1.28: 1. Etiological diagnosis was reached or considered probable in 41 (72%) cases out of the suspected patients. The most common etiological agent identified was enterovirus 71 in 20 patients (35.1 %). The other viruses identified were mumps in 6 (10.5%), Japanese encephalitis in 5 (8.7%), and measles in 4 (7%) cases. MRI brain was done in 39 patients and was abnormal in 14 patients. Out of 57 cases of suspected viral encephalitis 10 patients expired within 48 hours, 2 > 48 hours and 19 atients had significant neurological sequels at discharge. CONCLUSION:The etiology of acute febrile encephalopathy varies from infectious etiologies to noninfectious metabolic disorders. There are no distinguishing clinical or radiological features to differentiate the various causes of viral encephalitis. The clinical and the radiological findings in encephalitis should be interpreted in the geographical and other epidemiological background.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Karmarkar SA,Aneja S,Khare S,Saini A,Seth A,Chauhan BKdoi
10.1007/s12098-008-0150-2subject
Has Abstractpub_date
2008-08-01 00:00:00pages
801-5issue
8eissn
0019-5456issn
0973-7693journal_volume
75pub_type
杂志文章abstract:OBJECTIVE:To determine the utility of CSF Xpert MTB/RIF (GeneXpert) in diagnosis of tubercular meningitis in children in the age group of 2 mo to 12 y. METHODS:This hospital based prospective observational study was conducted at Department of Pediatrics, Karnataka Institute of Medical Sciences (KIMS), Hubli from Decem...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-019-03032-0
更新日期:2019-12-01 00:00:00
abstract::Anti-fungal agents are classified under two major headings, systematic and topical agents. Only systematic anti-fungal agents will be discussed in this chapter. Since the discovery in 1955, amphotericin B has been the cornerstone of anti-fungal treatment. It is active against most species of fungi. However, Candida lu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02752281
更新日期:2001-07-01 00:00:00
abstract::This editorial provides information on the first draft of the human genome, and examines the impact this will have on the practice of medicine, with special reference to India. It examines what is currently possible in India, what we should do in the immediate future, and what is in store in the long run. The future i...
journal_title:Indian journal of pediatrics
pub_type: 社论
doi:10.1007/BF02726224
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:Globally more than 1/3rd of the child deaths are attributed to under nutrition and it continues to be a major public health problem in developing countries. This research paper is an attempt towards intervention and management of severely malnourished children with the use of locally prepared therapeutic diet...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-015-1818-z
更新日期:2016-01-01 00:00:00
abstract::Anorectal malformations are one of the commonest anomalies in the new born. Major advances have been made in the last decade in operative techniques to reconstruct this abnormality. The final outcome in these babies is dependent on careful planning and operative intervention in the neonatal period. The purpose of this...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726272
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVES:The authors measured and recorded the physical (outdoor playing) and mental (home study) activity behavior and blood pressure amongst school going children and observed their association with the blood pressure levels. METHOD:It was a cross sectional school-based study from 12 primary schools; selected by s...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1007/BF02724095
更新日期:2004-04-01 00:00:00
abstract::The clinical disappearance of the murmur of rheumatic mitral regurgitation after period of time has been documented by many researchers. However no studies have related the disappearance of the murmur with the functional or anatomical state of the mitral valve. This study was done to elucidate the mitral valve status ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02825126
更新日期:1995-11-01 00:00:00
abstract::Airway malformations such as laryngeal atresia, tracheal agenesis and subglottic stenosis are rare and present at birth with significant respiratory distress with or without stridor. There may be an initial improvement on bag and mask ventilation. Repeated attempts at intubation are met with failure. The related embry...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02726024
更新日期:2002-11-01 00:00:00
abstract::Severely malnourished children (26), weight for age 55.27 +/- 3.17, were identified in a colony of predominantly Muslim urban slum dwellers of low economic status. An equal number of normally nourished children matched for age, sex and per capita income were identified. A strong relation was found between nutritional ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751136
更新日期:1991-03-01 00:00:00
abstract::Despite evidence about the value of high quality postnatal services for the survival, health and wellbeing of the mother and neonate, sub-optimal use of the available services delivered through public sector remains a persistent challenge in India and most low-middle income countries. An extensive search till Dec 31, ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-019-03101-4
更新日期:2020-03-01 00:00:00
abstract::Antimicrobial resistance is a key factor leading to emerging/ re-emerging infections. Rational antimicrobial therapy or antimicrobial stewardship is one of the important interventions to prevent emergence of resistance. Choosing correct empiric therapy is crucial not only to prevent antimicrobial resistance but also t...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-019-03144-7
更新日期:2020-11-01 00:00:00
abstract::It is common for primary care physicians to be faced with children with hematological disorders in everyday practice. The article seeks to provide realistic information for the first-contact physician in handling common hematological diseases in children. Practical step-wise approach to understanding and investigating...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1159-8
更新日期:2014-01-01 00:00:00
abstract::Approximately 25,000 children develop multidrug-resistant (MDR) tuberculosis (TB) each year, but few of them are diagnosed and appropriately treated for MDR-TB. New diagnostic tools have improved our ability to diagnose children with bacteriologically confirmed TB earlier. However, the majority of childhood TB cases a...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-018-02846-8
更新日期:2019-08-01 00:00:00
abstract::Growth monitoring and nutritional assessment, as means to detect malnutrition, are 2 different types of programs in terms of conception, purposes, and execution. Growth monitoring starts as detection of malnutrition, then acts through prevention by communication to mothers, and finally utilizes community participatio...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02810383
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the post treatment changes in disease activity and inflammatory markers over time in longitudinal follow-up involving different subtypes of juvenile idiopathic arthritis (JIA) patients. METHODS:This prospective longitudinal study, carried out over a period of 2 y, included JIA patients, both old ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2292-6
更新日期:2017-05-01 00:00:00
abstract::Due to changing characteristics of infective endocarditis in the past two decades, we, retrospectively analysed 28 cases of infective endocarditis in children of age less than 15 years at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar from December, 1983 to November, 1993. The incidence of disease was o...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02845245
更新日期:1996-03-01 00:00:00
abstract::Cerebral palsy is a common neurodevelopmental condition encountered by pediatricians. The condition may present itself in many different clinical spectra. The etiological and risk factors are many and an awareness of the interplay of multiple factors in the causation of CP is crucial. In many cases, the cause of Cereb...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02731117
更新日期:2005-10-01 00:00:00
abstract::The Asia Pacific Pediatric Association Vaccinology Update 2010 (APPA VU 2010) was held in Mumbai on November 13-14, 2010. This second part of the conference report discusses the interesting information about vaccines which are expected in the near future, namely, live-attenuated Japanese encephalitis virus vaccine, te...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0385-1
更新日期:2011-08-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 评论,社论,评审
doi:10.1007/s12098-018-2763-4
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To compare tympanic membrane temperature and rectal temperature in febrile pediatric patients. METHODS:Sixty febrile children were enrolled as continuous enrollment at initial triage. Two readings of ear temperature were taken in each child with Thermoscan infrared thermometer. Rectal temperature was recorde...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723215
更新日期:2002-04-01 00:00:00
abstract::The care of very-low-birth-weight infants has improved over the years with continuing changes in medical and nutritional management. In view of these changes, there is a need to study the pattern of postnatal weight gain. Postnatal weight gain patterns of 32 very-low-birth-weight infants were examined during the first...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/BF02845210
更新日期:1997-05-01 00:00:00
abstract::Microvillous inclusion disease (MVID), also known as congenital microvillus atrophy, was first described by Davidson et al. in 1978. Till date, only a handful of cases with MVID have been described in English literature. It is an autosomal recessive disorder with no sex predisposition and more commonly noted in countr...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-019-02963-y
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To devise some indicators for measuring and evaluating the neonatal cardiac reserve by using phonocardiogram test (PCGT). METHODS:Two hundred and thirty one (231) full term and one hundred and fifty four (154) preterm infants participated in this study. The amplitude ratio of the first heart sound to the sec...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0058-5
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To determine pulmonary function abnormalities in children with Sickle Cell Disease (SCD) from Western India. METHODS:In this cross sectional study conducted at Surat, Gujarat, India; equal number of age and gender matched children i.e., 99 in the age group of 6-18 y was recruited in case (children with SCD) ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2065-7
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of peripheral neuropathy in HIV infected children (>5 y) receiving stavudine-based combination anti-retroviral treatment (ART) for more than 3 mo in a cross-sectional study. METHODS:History, detailed neurological examination and nerve conduction studies were performed. RESULTS:Forty...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1477-5
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of all types of spacers commonly available to children in India. METHODS:150 children 5-14 yr of age with persistent asthma presenting with peak expiratory flow (PEF) < 70% of personal best were randomized to receive 200 mg salbutamol through one of five spacers: A) 750 ml spacer with...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12098-007-0112-0
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at l...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1415-6
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To study the etiology and burden of comorbidities across stages of chronic kidney disease (CKD). METHODS:Children, 2-16 y of age with CKD Stages II- IV were recruited over 12 mo. The etiology, clinical presentation and severity of complications were studied. RESULTS:Among 78 children [Stage II (n = 21), St...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2413-2
更新日期:2017-11-01 00:00:00
abstract::Deficiencies in intake of essential vitamins and minerals (commonly referred to as micronutrients) that are essential for efficient energy metabolism and other functions of the human body (commonly termed as micronutrients) are severe and widespread in many parts of the world. They cause an immeasurable burden on indi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02828115
更新日期:2004-11-01 00:00:00
abstract::Conducting economic evaluation alongside clinical trials is an efficient way of getting valid and reliable information with minimum assumptions made during data collection. However, design of a randomised control trial (RCT) takes away several of the real world situations, the variations in resource utilisation, their...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02820689
更新日期:2000-05-01 00:00:00