Challenges in human genetics in India in the new millennium.

Abstract:

:This editorial provides information on the first draft of the human genome, and examines the impact this will have on the practice of medicine, with special reference to India. It examines what is currently possible in India, what we should do in the immediate future, and what is in store in the long run. The future is indeed bright and India needs to expand the genetic services and research facilities.

journal_name

Indian J Pediatr

authors

Verma IC

doi

10.1007/BF02726224

keywords:

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

809-11

issue

11

eissn

0019-5456

issn

0973-7693

journal_volume

67

pub_type

社论
  • Ultrasound Examination of Pediatric Musculoskeletal Diseases and Neonatal Spine.

    abstract::Ultrasound (US) is a simple, non-invasive imaging modality which allows high-resolution imaging of the musculoskeletal (MSK) system. Its increasing popularity in pediatrics is due to the fact that it does not involve radiation, has an ability to visualize non-ossified cartilaginous and vascular structures, allows dyna...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-015-1957-2

    authors: Karnik AS,Karnik A,Joshi A

    更新日期:2016-06-01 00:00:00

  • Molecular diagnosis of infectious diseases.

    abstract::The Polymerase Chain Reaction (PCR) is a revolutionary new means of amplifying, i.e., replicating, selected DNA sequences in vitro. This procedure is highly sensitive and rapid, requiring few hours for detection of amplified target DNA whereas it often takes several weeks for the identification of many fastidious orga...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02737744

    authors: Raj P

    更新日期:1997-07-01 00:00:00

  • Relationship between Obesity Indices and Pulmonary Function Parameters in Obese Thai Children and Adolescents.

    abstract:OBJECTIVE:To determine the correlation between various obesity indices and pulmonary function parameters in obese Thai children and adolescents. METHODS:Obese children and adolescents aged from 8 to 18 y and diagnosed under the criteria of International Obesity Task Force (IOTF) were enrolled. Anthropometric and body ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-015-1777-4

    authors: Kongkiattikul L,Sritippayawan S,Chomtho S,Deerojanawong J,Prapphal N

    更新日期:2015-12-01 00:00:00

  • Issues in the diagnosis and management of disorders of sexual development.

    abstract::Disorders of sexual development (DSD) are a complex group of disorders to manage, not only because the diagnosis is difficult, but also because it involves many factors related to the psychosexual well being, the social stigma associated with the disorder, confusion and reluctance on the part of medical professionals ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-013-1168-7

    authors: Khadilkar VV,Phanse-Gupte S

    更新日期:2014-01-01 00:00:00

  • Diagnosis and management of primary pulmonary hypertension.

    abstract::Pulmonary arterial hypertension in children can occur secondary to shunt lesion like ventricular septal defect, patent ductus arteriosus or it may be idiopathic, the so called primary pulmonary hypertension (PPH). The progression of PPH is usually rapid in children as compared to adults and the mean survival is 2-3 ye...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Krishnan U

    更新日期:2000-03-01 00:00:00

  • Integrated Management of Childhood Illness (IMCI): a robust strategy.

    abstract::Integrated Management of Childhood Illness (IMCI), a strategy fostering holistic approach to child health and development, is built upon successful experiences gained from effective child health interventions like immunization, oral rehydration therapy, management of acute respiratory infections and improved infant fe...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02723776

    authors: Patwari AK,Raina N

    更新日期:2002-01-01 00:00:00

  • Congenital tuberculosis.

    abstract::A 29 day old male infant presented with a history of fever, cough, increasing respiratory distress and abdominal distension from the 10th day of life. Examination revealed failure to thrive, marked tachypnea, pallor, hepatosplenomegaly and harsh vesicular breath sounds. Chest skiagram showed extensive broncho-pneumoni...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02752376

    authors: Balasubramanian S,Shivram R,Padmasani LN,Nagaraju

    更新日期:1999-01-01 00:00:00

  • Clinical and hormonal studies in precocious puberty.

    abstract::Data from 31 children, 23 females (74.2%) and eight males (25.8%) with precocious puberty were analysed. They included 19 cases with central precocious puberty, 5 with premature thelarche, 5 with premature adrenarche and 1 each with adrenal adenoma and virilizing hepatoblastoma. Their clinical and hormonal profile and...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02727928

    authors: Khandekar S,Dash RJ

    更新日期:1990-05-01 00:00:00

  • Impact of Leadership of Trained Intensivist in Pediatric Intensive Care Unit in a Middle Income Country: An Uncontrolled Before-After Study.

    abstract:OBJECTIVE:To evaluate the effects generated by an intensivist in pediatric intensive care unit (PICU) on the process of care and patient outcomes. METHODS:This study was a retrospective observational study conducted in the 16-bedded PICU of a tertiary referral center. Two years (2013-2015) period of the PICU without a...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-019-03154-5

    authors: Kesici S,Bayrakci B

    更新日期:2020-04-01 00:00:00

  • Prevalence and correlates of diarrhea.

    abstract:OBJECTIVE:The present study aimed to estimate the prevalence of acute diarrhea and its correlates in remote rural villages of south Pakistan. METHODS:The authors selected 1878 children less than 3 years of age through stratified random sampling from 64 villages having the number of children enrolled proportionate to t...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02725583

    authors: Shah SM,Yousafzai M,Lakhani NB,Chotani RA,Nowshad G

    更新日期:2003-03-01 00:00:00

  • Prevalence of cholera in pediatric patients with acute dehydrating diarrhea.

    abstract:OBJECTIVE:To estimate the prevalence of culture-confirmed cholera in patients with acute dehydrating diarrhea, at a tertiary care center in north India, during a 6-month period from March to August, 2006. METHODS:We studied 145 children, who presented to the pediatric emergency services of a tertiary care teaching hos...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-010-0009-1

    authors: Kuttiat VS,Lodha R,Das B,Kohli U

    更新日期:2010-01-01 00:00:00

  • Epidemiology and control of malaria.

    abstract::Malaria is essentially a local and focal disease since its transmission depends greatly on local eco-environmental conditions. In India, the incidence of total malaria cases has been contained to around 2-3 million cases per year. However, with the occurrence of outbreaks in different parts of the country since 1994, ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02727167

    authors: Lal S,Dhillon GP,Aggarwal CS

    更新日期:1999-07-01 00:00:00

  • Near fatal case of amlodipine poisoning in an infant.

    abstract::An 11-mo-old infant received 12.5 times the maximum therapeutic dose of amlodipine as a result of a medication error in lieu of amoxicillin. He presented with vomiting, lethargy, breathlessness, muffled heart sounds and progressed to hypotensive shock within three hours of admission. He received mechanical ventilation...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-012-0861-2

    authors: Nimbalkar SM,Patel DV

    更新日期:2013-06-01 00:00:00

  • Bacterial meningitis in Saudi children.

    abstract::During the four years period from 1988 to 1991, 50 pediatric patients were diagnosed to have bacterial meningitis, out of a total number of 9057 pediatric admissions at Qatif Central Hospital, Qatif, Saudi Arabia, and 82% were less than two years of age. The causative organisms were isolated in 27 (54%) patients. The ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02859407

    authors: Srair HA,Aman H,al-Madan M,al-Khater M

    更新日期:1992-11-01 00:00:00

  • Reversibility of mitral regurgitation following rheumatic fever: clinical profile and echocardiographic evaluation.

    abstract::The clinical disappearance of the murmur of rheumatic mitral regurgitation after period of time has been documented by many researchers. However no studies have related the disappearance of the murmur with the functional or anatomical state of the mitral valve. This study was done to elucidate the mitral valve status ...

    journal_title:Indian journal of pediatrics

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    doi:10.1007/BF02825126

    authors: Kassem AS,el-Walili TM,Zaher SR,Ayman M

    更新日期:1995-11-01 00:00:00

  • Genetic counseling.

    abstract::Genetic counseling is a process of communicating medical aspects about a genetic disorder, especially the information regarding risk of occurrence as recurrence of the disease in the family and preventive options. Accurate diagnosis of the affected member is of paramount importance for genetic counseling. Special gene...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02723098

    authors: Phadke SR

    更新日期:2004-02-01 00:00:00

  • Pediatric Asthma and Food Allergy.

    abstract:OBJECTIVE:To quantitatively summarize the evidence from observational studies on the relation between pediatric asthma and food allergy. METHODS:A literature search was conducted in Medline and EMBASE (August 2016). Two independent reviewers appraised the studies and extracted the estimates of interest. Methodological...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12098-017-2326-0

    authors: Zhou H,Dai C,Pan J

    更新日期:2017-08-01 00:00:00

  • Kawasaki disease.

    abstract::Kawasaki disease (KD) is a systemic necrotizing vasculitis affecting medium and small sized arteries. The diagnosis is based entirely on recognition of a typical sequence of clinical features. Detection of any one clinical feature does not have any diagnostic significance. We report an uncommon case of Kawasaki diseas...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02722603

    authors: Saraf S,Singh RK

    更新日期:2001-10-01 00:00:00

  • Neonatal Sepsis: Mortality and Morbidity in Neonatal Sepsis due to Multidrug-Resistant (MDR) Organisms: Part 1.

    abstract::The major causes of emergence of multidrug-resistant organisms (MDRO) in neonatal sepsis include empiric antibiotic prescriptions, unregulated use of over-the-counter drugs, high incidence of healthcare associated infections (HAI), lack of awareness about antibiotic stewardship program and under staffing of neonatal i...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-019-03106-z

    authors: Wattal C,Kler N,Oberoi JK,Fursule A,Kumar A,Thakur A

    更新日期:2020-02-01 00:00:00

  • Movement assessment of infants as a predictor of one year neuromotor outcome in very low birth weight infants.

    abstract:OBJECTIVE:To predict neuromotor outcome in Very Low Birth Weight infants at 1 year using Movement Assessment of Infants scale at 4 and 8 months of corrected age. METHODS:This hospital based prospective observational study consecutively recruited 45 infants with birth weight ≤ 1,500 g and admitted to neonatal intensive...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0468-z

    authors: Metgud DC,Patil VD,Dhaded SM

    更新日期:2011-11-01 00:00:00

  • Management of infants with intra-uterine growth restriction.

    abstract::Intra-uterine growth restriction (IUGR) contributes to almost two-thirds of LBW infants born in India. Poor nutritional status and frequent pregnancies are common pre-disposing conditions in addition to obstetric and medical problems during pregnancy. Growth restriction may be symmetrical or asymmetrical depending on ...

    journal_title:Indian journal of pediatrics

    pub_type:

    doi:10.1007/s12098-008-0025-6

    authors: Deorari AK,Agarwal R,Paul VK

    更新日期:2008-02-01 00:00:00

  • Glial choristoma.

    abstract::Glial choristoma is a developmental malformation of heterotopic central nervous tissue with limited growth potential. It is considered to be one of the very rare choristomatous lesions involving the oral cavity. This report details the morphological characteristics of glial choristoma arising from the palate in a newb...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02722638

    authors: Bajaj P,Shubha BS,Agarwal K,Aggarwal C

    更新日期:2002-05-01 00:00:00

  • Bronchopulmonary dysplasia in very low birth weight infants.

    abstract:OBJECTIVE:The developments in newborn care have enabled many more very low birth weight premature infants to live. The aim of our study was to determine the risk factors for bronchopulmonary dysplasia (BPD) development by evaluating mild and moderate/severe BPD in extramural neonates with a birth weight <1501 g. METHO...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0110-5

    authors: Demirel N,Bas AY,Zenciroglu A

    更新日期:2009-07-01 00:00:00

  • Why infant mortality is low in Kerala.

    abstract::The reasons for comparatively low infant mortality rates in the Indian state of Kerala are examined. The importance of improvements in education and in the health care delivery system is stressed. ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02751009

    authors: Philip E

    更新日期:1985-09-01 00:00:00

  • Comparison of Temporal Artery Thermometry with Axillary and Rectal Thermometry in Full Term Neonates.

    abstract:OBJECTIVE:To assess the efficacy of temporal artery thermometer in febrile and hypothermic neonates in comparison to axillary thermometer. METHODS:It was a cross sectional observational study. Study participants included 210 neonates admitted in neonatal intensive care unit of a tertiary care teaching hospital, divide...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-016-2259-z

    authors: Goswami E,Batra P,Khurana R,Dewan P

    更新日期:2017-03-01 00:00:00

  • "Rationalization of Empiric Antibiotic Therapy" - A Move Towards Preventing Emergence of Resistant Infections.

    abstract::Antimicrobial resistance is a key factor leading to emerging/ re-emerging infections. Rational antimicrobial therapy or antimicrobial stewardship is one of the important interventions to prevent emergence of resistance. Choosing correct empiric therapy is crucial not only to prevent antimicrobial resistance but also t...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-019-03144-7

    authors: Singhal T

    更新日期:2020-11-01 00:00:00

  • Recombinant activated factor VII usage in life threatening hemorrhage: a pediatric experience.

    abstract:OBJECTIVE:To determine the safety and efficacy of off label usage of Recombinant activated factor VII (rFVIIa) in children with severe bleeding in non-hemophiliac children with diverse etiologies like leukemia, post hematopoietic stem cell transplantation, dengue shock syndrome and Glanzmann thrombasthenia. METHOD:Med...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0364-6

    authors: Bhat S,Yadav SP,Anjan M,Dinand V,Sachdeva A

    更新日期:2011-08-01 00:00:00

  • Recent advances in the management of non-specific aorto-arteritis.

    abstract::Non-Specific Aorto-arteritis or Takayasu's arteritis (TA) is a chronic inflammatory disease of the aorta and its major branches which either presents with constitutional symptoms in its active phase or with steno-occlusive symptoms in the healing phase. In children, it is an aggressive disease and often lethal. Conges...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02722657

    authors: Vijayalakshmi

    更新日期:2002-06-01 00:00:00

  • Intravenous arginine vasopressin infusion in refractory vasodilatory shock: a clinical study.

    abstract:OBJECTIVE:To assess the efficacy of arginine vasopressin (AVP) as a rescue therapy in children with catecholamine refractory vasodilatory shock and its effect on various hemodynamic, clinical, and laboratory variables. METHODS:This prospective hospital based study was conducted from January 2008 through July 2008 at a...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-011-0557-z

    authors: Agrawal A,Singh VK,Varma A,Sharma R

    更新日期:2012-04-01 00:00:00

  • Liver involvement in celiac disease.

    abstract::Celiac disease may present as a cryptogenic liver disorder being found in 5-10 % of patients with a persistent and cryptogenetic elevation of serum aminotransferase activity. In fact, a wide spectrum of liver injuries in children and adults may be related to CD and in particular: (1) a mild parenchymal damage characte...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02790391

    authors: Maggiore G,Caprai S

    更新日期:2006-09-01 00:00:00