Abstract:
:Recent theories of selective attention assume that the more attention is required by a task, the earlier are irrelevant stimuli filtered during perceptual processing. Previous functional MRI studies have demonstrated that primary visual cortex (V1) activation by peripheral distractors is reduced by higher task difficulty at fixation, but it remains unknown whether such changes affect initial processing in V1 or subsequent feedback. Here we manipulated attentional load at fixation while recording peripheral visual responses with high-density EEG in 28 healthy volunteers, which allowed us to track the exact time course of attention-related effects on V1. Our results show a modulation of the earliest component of the visual evoked potential (C1) as a function of attentional load. Additional topographic and source localization analyses corroborated this finding, with significant load-related differences observed throughout the first 100 ms post-stimulus. However, this effect was observed only when stimuli were presented in the upper visual field (VF), but not for symmetrical positions in the lower VF. Our findings demonstrate early filtering of irrelevant information under increased attentional demands, thus supporting models that assume a flexible mechanism of attentional selection, but reveal important functional asymmetries across the VF.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Rauss KS,Pourtois G,Vuilleumier P,Schwartz Sdoi
10.1002/hbm.20636subject
Has Abstractpub_date
2009-05-01 00:00:00pages
1723-33issue
5eissn
1065-9471issn
1097-0193journal_volume
30pub_type
杂志文章abstract::Socially appropriate behavior requires the concurrent inhibition of actions that are inappropriate in the context. This self-regulatory function requires an interaction of inhibitory and emotional processes that recruits brain regions beyond those engaged by either processes alone. In this study, we isolated brain act...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20706
更新日期:2009-09-01 00:00:00
abstract::Constrained spherical deconvolution (CSD) of diffusion-weighted MRI (DW-MRI) is a popular analysis method that extracts the full white matter (WM) fiber orientation density function (fODF) in the living human brain, noninvasively. It assumes that the DW-MRI signal on the sphere can be represented as the spherical conv...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25241
更新日期:2020-11-10 00:00:00
abstract::Neural dynamics can shape human experience, including pain. Pain has been linked to dynamic functional connectivity within and across brain regions of the dynamic pain connectome (consisting of the ascending nociceptive pathway (Asc), descending antinociceptive pathway (Desc), salience network (SN), and the default mo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25245
更新日期:2021-02-15 00:00:00
abstract::Previous studies have demonstrated that the right ventrolateral prefrontal cortex (RVLPFC) is crucially involved in downregulating physical and social pain. However, it remains unclear whether the RVLPFC is more specific to either physical or social pain. The present study compares the role of RVLPFC in emotion regula...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24881
更新日期:2020-04-01 00:00:00
abstract::Fluid intelligence (gf) refers to abstract reasoning and problem solving abilities. It is considered a human higher cognitive factor central to general intelligence (g). The regions of the cortex supporting gf have been revealed by recent bioimaging studies and valuable hypothesis on the neural correlates of individua...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20519
更新日期:2009-02-01 00:00:00
abstract::The reason why human beings are inclined to overestimate the duration of highly arousing negative events remains enigmatic. The issue about what neurocognitive mechanisms and neural structures support the connection between time perception and emotion was addressed here by an event-related neuroimaging study involving...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22680
更新日期:2015-03-01 00:00:00
abstract::Neural dynamics leading to conscious sensory perception have remained enigmatic in despite of large interest. Human functional magnetic resonance imaging (fMRI) studies have revealed that a co-activation of sensory and frontoparietal areas is crucial for conscious sensory perception in the several second time-scale of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23033
更新日期:2016-01-01 00:00:00
abstract::We describe a system that localizes a single dipole to reasonable accuracy from noisy magnetoencephalographic (MEG) measurements in real time. At its core is a multilayer perceptron (MLP) trained to map sensor signals and head position to dipole location. Including head position overcomes the previous need to retrain ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20068
更新日期:2005-01-01 00:00:00
abstract::This paper describes a Bayesian method for three-dimensional registration of brain images. A finite element approach is used to obtain a maximum a posteriori estimate of the deformation field at every voxel of a template volume. The priors used by the MAP estimate penalize unlikely deformations and enforce a continuou...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(200004)9:4<212::aid-hbm3>3
更新日期:2000-04-01 00:00:00
abstract::Previous studies have shown that white matter in the deaf brain changes due to hearing loss. However, how white-matter development is influenced by early hearing experience of deaf people is still unknown. Using diffusion tensor imaging and tract-based spatial statistics, we compared white-matter structures among thre...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21215
更新日期:2012-02-01 00:00:00
abstract::Despite a growing number of reports about alterations in intrinsic/resting brain activity observed in patients with psychotic disorders, their relevance to well-established cognitive control deficits in this patient group is not well understood. Totally 88 clinically stabilized patients with a psychotic disorder and 5...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24362
更新日期:2019-01-01 00:00:00
abstract::We describe a method for the statistical parametric mapping of low resolution electromagnetic tomography (LORETA) using high-density electroencephalography (EEG) and individual magnetic resonance images (MRI) to investigate the characteristics of the mismatch negativity (MMN) generators in schizophrenia. LORETA, using...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10059
更新日期:2002-11-01 00:00:00
abstract::Gait disturbances, including freezing of gait, are frequent and disabling symptoms of Parkinson's disease. They often respond poorly to dopaminergic treatments. Although recent studies have shed some light on their neural correlates, their modulation by dopaminergic treatment remains quite unknown. Specifically, the i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22679
更新日期:2015-03-01 00:00:00
abstract::Recently, it has been suggested that backwardly masked, and thus subliminally presented, fearful eyes are processed by the amygdala. Here, we investigated in four functional magnetic resonance imaging experiments whether the amygdala responds to subliminally presented fearful eyes per se or whether an interaction of m...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20960
更新日期:2010-10-01 00:00:00
abstract::Multicenter structural MRI studies can have greater statistical power than single-center studies. However, across-center differences in contrast sensitivity, spatial uniformity, etc., may lead to tissue classification or image registration differences that could reduce or wholly offset the enhanced statistical power o...
journal_title:Human brain mapping
pub_type: 杂志文章,多中心研究
doi:10.1002/hbm.20991
更新日期:2010-12-01 00:00:00
abstract::Recent evidence suggests that deficits of working memory may be a promising neurocognitive endophenotype of bipolar affective disorder. However, little is known about the neurobiological correlates of these deficits. The aim of this study was to determine possible pathophysiological trait markers of bipolar disorder i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20849
更新日期:2010-01-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) were used to map brain activation during language tasks. While previous studies have compared performance between alphabetic literate and illiterate subjects, there have been no such data in Chinese-speaking individuals. In this study,...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20173
更新日期:2006-02-01 00:00:00
abstract::The dorsal attention network (DAN), including frontal eye fields and posterior parietal cortices, and its link with the posterior thalamus, contribute to visual-spatial abilities. Very premature birth impairs both visual-spatial abilities and cortico-thalamic structural connectivity. We hypothesized that impaired stru...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24685
更新日期:2019-10-01 00:00:00
abstract::Impairment in controlled semantic association is a central feature of schizophrenia, and the goal of the current functional magnetic resonance imaging study was to identify the neural correlates of this impairment. Thirty people with schizophrenia and 30 healthy age- and gender-matched control subjects performed a tas...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22820
更新日期:2015-08-01 00:00:00
abstract::Diffusion-weighted magnetic resonance imaging allows researchers and clinicians to identify individual white matter fiber tracts and map their trajectories. The reliability and interpretability of fiber-tracking procedures is improved when a priori anatomical information is used as a guide. We have developed an automa...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20619
更新日期:2009-05-01 00:00:00
abstract::Though fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorders are among the most common developmental disorders, their understanding is incomplete. Diffusion tensor imaging (DTI), which is sensitive to microstructural organization in white matter, may provide a relevant measure in this population demonstrat...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20747
更新日期:2009-10-01 00:00:00
abstract::Recognizing the identity of other individuals across different sensory modalities is critical for successful social interaction. In the human brain, face- and voice-sensitive areas are separate, but structurally connected. What kind of information is exchanged between these specialized areas during cross-modal recogni...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22631
更新日期:2015-01-01 00:00:00
abstract::Standardized psychometric tests are sophisticated, well-developed, and consequential instruments; test outcomes are taken as facts about people that impact their lives in important ways. As part of an initial demonstration that human brain mapping techniques can add converging neural-level evidence to understanding st...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23761
更新日期:2017-11-01 00:00:00
abstract::Huntington's disease (HD) is a neurodegenerative disorder which is primarily associated with striatal degeneration. However, the alterations in connectivity of this structure in HD have been underinvestigated. In this study, we analyzed the functional and structural connectivity of the left putamen, while participants...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23813
更新日期:2018-01-01 00:00:00
abstract::Fetal alcohol spectrum disorders (FASD) are debilitating, with effects of prenatal alcohol exposure persisting into adolescence and adulthood. Complete characterization of FASD is crucial for the development of diagnostic tools and intervention techniques to decrease the high cost to individual families and society of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22110
更新日期:2013-11-01 00:00:00
abstract::Experienced video game players exhibit superior performance in visuospatial cognition when compared to non-players. However, very little is known about the relation between video game experience and structural brain plasticity. To address this issue, a direct comparison of the white matter brain structure in RTS (real...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24208
更新日期:2018-09-01 00:00:00
abstract::The use of functional magnetic resonance imaging (fMRI) to explore central auditory function may be compromised by the intense bursts of stray acoustic noise produced by the scanner whenever the magnetic resonance signal is read out. We present results evaluating the use of one method to reduce the effect of the scann...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0193(1999)7:3<213::aid-hbm5>3.0
更新日期:1999-01-01 00:00:00
abstract::Puberty represents the phase of sexual maturity, signaling the change from childhood into adulthood. During childhood and adolescence, prominent changes take place in the brain. Recently, variation in frontal, temporal, and parietal areas was found to be under varying genetic control between 5 and 19 years of age. How...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20660
更新日期:2009-07-01 00:00:00
abstract::We present a novel, computerized method of examining cerebral cortical thickness. The normal cortex varies in thickness from 2 to 4 mm, reflecting the morphology of neuronal sublayers. Cortical pathologies often manifest abnormal variations in thickness, with examples of Alzheimer's disease and cortical dysplasia as t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/1097-0193(200009)11:1<12::aid-hbm20>3.0.co
更新日期:2000-09-01 00:00:00
abstract::The spatial organization of nonlinear interactions between different brain regions during the first NREM sleep stage is investigated. This is achieved via consideration of four bipolar electrode derivations, Fp1F3, Fp2F4, O1P3, O2P4, which are used to compare anterior and posterior interhemispheric interactions and le...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20052
更新日期:2004-10-01 00:00:00