Abstract:
:The biochemical basis of a defective bioenergetic system was attempted to be determined in N,N'-dicyclohexylcarbodiimide (DCCD)-resistant mutant of Methanothermobacter thermautotrophicus. Components participating in the maintenance of methanoarchaeal membrane structure and function, such as the composition of the mixture of squalene and its hydrosqualene derivatives and also properties of membrane-associated proteins were compared in wild-type and mutant cells. The impairment of the bioenergetic system in DCCD-resistant mutant was detectable in the membrane-protein profile; it was also accompanied by changes in proportions of squalene-hydrosqualenes.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Nováková Z,Surín S,Blasko J,Majerník A,Smigán Pdoi
10.1007/s12223-008-0034-xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
237-40issue
3eissn
0015-5632issn
1874-9356journal_volume
53pub_type
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