15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.

abstract：:Recent data indicate that the Simian virus 40 (SV40) infection appears to be transmitted in humans independently from early SV40-contaminated antipolio vaccines. Serum antibodies against SV40 large T antigen (Tag) were analyzed in children/adolescents and young adults. To investigate antibodies reacting to SV40 Tag an...

journal_title：Journal of cellular physiology

authors： Mazzoni E,Frontini F,Rotondo JC,Zanotta N,Fioravanti A,Minelli F,Torreggiani E,Campisciano G,Marcuzzi A,Guerra G,Tommasini A,Touzé A,Martini F,Tognon M,Comar M

更新日期：2019-04-01 00:00:00

abstract：:High potassium concentrations altered the morphology and the ability to grow in soft agar in 6m2 cells, a clone of rat kidney cells infected with a temperature-sensitive mutant of Moloney sarcoma virus. Approximately 60% of cells exhibited normal morphology in the presence of 94.8 mM potassium in isotonic medium at th...

journal_title：Journal of cellular physiology

authors： Lai CN,Becker FF

更新日期：1985-11-01 00:00:00

abstract：:We demonstrated previously that in serum-starved MCF-7 breast cancer cell line, Ang II increased Na+/K+ATPase activity and activated the protein kinase C zeta (PKC-zeta) (Muscella et al., 2002 J Endocrinol 173:315-323; 2003 J Cell Physiol 197:61-68.). The aim of the present study was to investigate the modulation of t...

journal_title：Journal of cellular physiology

authors： Muscella A,Storelli C,Marsigliante S

更新日期：2005-11-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (MCF-7/deltaA(FGF)(18...

journal_title：Journal of cellular physiology

authors： Wieder R,Fenig E,Wang H,Wang Q,Paglin S,Menzel T,Gabrilove J,Fuks Z,Yahalom J

更新日期：1998-12-01 00:00:00

abstract：:Transformation of Sprague-Dawley rat embryo (RE) cells and a cloned Fischer rat embryo cell line (CREF) with wild-type (Ad5) or a temperature-sensitive DNA-minus mutant (H5ts125) of type 5 adenovirus results in a reduction in binding of epidermal growth factor (EGF) to cell surface receptors. A reduction in EGF bindin...

journal_title：Journal of cellular physiology

authors： Fisher PB,Boersig MR,Graham GM,Weinstein IB

更新日期：1983-03-01 00:00:00

abstract：:Previous study suggested that the receptor component protein (RCP), one of the components of calcitonin gene-related peptide (CGRP) receptor, plays a multiple role in the cellular signal transduction. The study was designed to investigate whether or not the RCP involved in the regulation of caveolin-1/extracellular si...

journal_title：Journal of cellular physiology

authors： Guo F,Yang L,Luo J,Quan H,Wang Z,Peng H,Hong C,Li J,Jiang Z,Zhang L,Qin X

更新日期：2018-10-01 00:00:00

abstract：:Glutathione S-transferases (GSTs) are enzymes that are involved in the detoxification of harmful electrophilic endogenous and exogenous compounds by conjugating with glutathione (GSH). The liver fluke GSTs have multifunctional roles in the host-parasite interaction, such as general detoxification and bile acid sequest...

journal_title：Journal of cellular physiology

authors： Kalita J,Shukla R,Tripathi T

更新日期：2019-04-01 00:00:00

abstract：:K+ channels of the alveolar epithelium control the driving force acting on the ionic and solvent flow through the cell membrane contributing to the maintenance of cell volume and the constitution of epithelial lining fluid. In the present work, we analyze the effect of the Cl- channel inhibitors: (4-[(2-butyl-6,7-dich...

journal_title：Journal of cellular physiology

authors： Canella R,Martini M,Cavicchio C,Cervellati F,Benedusi M,Valacchi G

更新日期：2019-08-01 00:00:00

abstract：:The human cervical cancer (CC) has been identified as one of the most common tumors in women, and the molecular regulation in CC still remains unclear. The dysregulation of periostin has been found in a variety of cancers, but whether it is involved in the regulation of CC is unknown. The present study aimed to invest...

journal_title：Journal of cellular physiology

authors： Han X,Wang Q,Wang Y,Hu B,Dong X,Zhang H,Wang W

更新日期：2019-08-01 00:00:00

abstract：:Considerable evidence has accumulated for a role of a nonsteroidal mevalonate product in the regulation of DNA replication and cell division. We report here a similar requirement for mevalonate in a nonreplicative function, that of natural killer (NK) cell cytotoxicity. Treatment of NK cells with 10 microM compactin f...

journal_title：Journal of cellular physiology

authors： Cutts JL,Scallen TJ,Watson J,Bankhurst AD

更新日期：1989-06-01 00:00:00

abstract：:Resistin, secreted by macrophages in tumor microenvironment, has never been investigated in pancreatic cancer models, despite a vibrant tumor microenvironment around pancreatic tumors. We evaluated serum resistin levels in healthy individuals versus pancreatic cancer patients representing different tumor grades. In vi...

journal_title：Journal of cellular physiology

authors： Zhang M,Yan L,Wang GJ,Jin R

更新日期：2019-06-01 00:00:00

abstract：:We examined the expression of the estrogen and epidermal growth factor (EGF) receptors in a drug-resistant subline of MCF-7 cells in order to study potential alterations in hormone dependence or in the growth factor pathway that could be related to the development of drug resistance in human breast cancer. The drug-re...

journal_title：Journal of cellular physiology

authors： Dickstein B,Valverius EM,Wosikowski K,Saceda M,Pearson JW,Martin MB,Bates SE

更新日期：1993-10-01 00:00:00

abstract：:Wnt5a, a member of the noncanonical Wnt proteins, is known to play important roles in the development of various organs and in postnatal cell functions. However, little is known about the effects of Wnt5a on human periodontal ligament (PDL) cells. In this study, we examined the localization and potential function of W...

journal_title：Journal of cellular physiology

authors： Hasegawa D,Wada N,Maeda H,Yoshida S,Mitarai H,Tomokiyo A,Monnouchi S,Hamano S,Yuda A,Akamine A

更新日期：2015-11-01 00:00:00

abstract：:Resistin, firstly reported as an adipocyte-specific hormone, is suggested to be an important link between obesity and diabetes. Recent studies have suggested an association between resistin and atherogenic processes. The adhesion of circulating monocytes to endothelial cells is a critical step in the early stages of a...

journal_title：Journal of cellular physiology

authors： Hsu WY,Chao YW,Tsai YL,Lien CC,Chang CF,Deng MC,Ho LT,Kwok CF,Juan CC

更新日期：2011-08-01 00:00:00

abstract：:The effect of epinephrine was tested on the proliferation of rat arterial smooth muscle cells (SMC) in secondary cultures. Epinephrine added daily to the culture medium caused a striking stimulation of growth. The effect increased with time and was dose-dependent. Maximal stimulation was observed at a concentration of...

journal_title：Journal of cellular physiology

authors： Blaes N,Boissel JP

更新日期：1983-08-01 00:00:00

abstract：:We have partially purified a mitogenic factor, termed colony stimulating factor, which is secreted from a human T lymphocytic cell line, and which stimulates in vitro formation of colonies of macrophages and granulocytes by human bone marrow cells. Colony stimulating factor (CSF) produced by cells grown in serum suppl...

journal_title：Journal of cellular physiology

authors： Frölich M

更新日期：1981-12-01 00:00:00

abstract：:The roles of Sonic hedgehog (Shh) and Bone morphogenetic protein-2 (Bmp-2) in osteoblast differentiation were investigated using in vitro cell systems. Recombinant amino-terminal portion of SHH (rSHH-N) dose dependently stimulated ALP activity in C3H10T1/2 and MC3T3-E1 cells. rSHH-N induced expression of Osteocalcin m...

journal_title：Journal of cellular physiology

authors： Yuasa T,Kataoka H,Kinto N,Iwamoto M,Enomoto-Iwamoto M,Iemura S,Ueno N,Shibata Y,Kurosawa H,Yamaguchi A

更新日期：2002-11-01 00:00:00

abstract：:The etiology of endometriosis, a gynecological disease characterized by the presence of endometrial glands and stroma outside the uterine cavity, is still unknown. Our research group has recently demonstrated the presence of ectopic endometrium in human female fetuses at different gestational ages. In this manuscript ...

journal_title：Journal of cellular physiology

authors： Signorile PG,Baldi F,Bussani R,Viceconte R,Bulzomi P,D'Armiento M,D'Avino A,Baldi A

更新日期：2012-04-01 00:00:00

abstract：:Human promyelocytic leukemia (HL-60) cells display a novel voltage-dependent outward current under voltage clamp. This current is present at low levels in the proliferative state and in granulocytes derived from HL-60 cells which were induced to differentiate with retinoic acid. It is elevated in macrophages derived f...

journal_title：Journal of cellular physiology

authors： Wieland SJ,Chou RH,Chen TA

更新日期：1987-08-01 00:00:00

abstract：:A proliferation inducing ligand (APRIL or TALL-2 and TRDL-1) was first discovered as a cytokine over-expressed in many transformed cells and with the capacity to stimulate proliferation. APRIL was shown to bind two different receptors of the TNF receptor superfamily: B cell maturation antigen (BCMA) and transmembrane ...

journal_title：Journal of cellular physiology

authors： Kimberley FC,Hahne M,Medema JP

更新日期：2009-01-01 00:00:00

abstract：:Protein-DNA interactions within the promoter of a cell cycle-regulated human H4 histone gene were examined by binding of 5'-end-labeled DNA segments to Western blots of nuclear protein fractions. Specific protein interactions were observed with DNA segments located between -500 bp and -1,070 bp upstream of the ATG ini...

journal_title：Journal of cellular physiology

authors： Pauli U,Chiu JF,Ditullio P,Kroeger P,Shalhoub V,Rowe T,Stein G,Stein J

更新日期：1989-05-01 00:00:00

abstract：:Studies were conducted to explore hormonal and nutritional factors that might be involved in the regulation of retinol-binding protein (RBP) synthesis and secretion by the liver. The studies employed primary cultures of hepatocytes from normal rats. When cells were cultured in Dulbecco's modified Eagle's medium alone,...

journal_title：Journal of cellular physiology

authors： Dixon JL,Goodman DS

更新日期：1987-01-01 00:00:00

abstract：:To reduce embryonic losses in domestic animals for economic production of livestock meat and milk, chemokines and their receptors are required for proper implantation and placentation during early pregnancy. In this study, we investigated the effects of C-C-motif chemokine ligand 23 (CCL23) on the proliferation of bov...

journal_title：Journal of cellular physiology

authors： Lim W,Bae H,Bazer FW,Song G

更新日期：2018-04-01 00:00:00

abstract：:Apelin is an endogenous ligand of seven-transmembrane G protein-coupled receptor APJ. Apelin and APJ are distributed in various tissues, including the heart, lung, kidney, and even in tumor tissues. Studies show that apelin mRNA is highly expressed in the inner stripe of kidney outer medulla, which plays an important ...

journal_title：Journal of cellular physiology

authors： Huang Z,Wu L,Chen L

更新日期：2018-05-01 00:00:00

abstract：:The endocannabinoid system (ECS) is activated at the onset of obesity and diverse metabolic diseases. Endocannabinoids mediate their physiological and behavioral effects by activating specific cannabinoid receptors, mainly cannabinoid receptor 1 (CB(1)R). Diabetic nephropathy (DN) is induced by hyperlipidemia, and ren...

journal_title：Journal of cellular physiology

authors： Lim JC,Lim SK,Han HJ,Park SH

更新日期：2010-11-01 00:00:00

abstract：:A cloned human hepatoma cell line (Li-7A), possessing epidermal growth factor (EGF) receptors numbering in the range of 10-20 pmol/10(6) cells, was inhibited in its growth by EGF as well as an antagonist monoclonal antibody (MoAb) to the EGF receptor. The mode of action of the two ligands of EGF receptors appeared to ...

journal_title：Journal of cellular physiology

authors： Knowles AF

更新日期：1988-01-01 00:00:00

abstract：:Tumors and multicellular tumor spheroids can develop gradients in oxygen concentration, glucose concentration, and extracellular pH as they grow. In order to calculate these gradients and assess their impact on tumor growth, it is necessary to quantify the effect of these variables on tumor cell metabolism and growth....

journal_title：Journal of cellular physiology

authors： Casciari JJ,Sotirchos SV,Sutherland RM

更新日期：1992-05-01 00:00:00

abstract：:Vero M3 cells, a line derived from the kidney of an African Green Monkey, display certain alterations in their protein synthetic apparatus as a function of time during a growth cycle. (Growth cycle here refers to exponential growth of unsynchronized cells in culture and their subsequent passage into the stationary pha...

journal_title：Journal of cellular physiology

authors： Engelhardt DL,Sarnoski J

更新日期：1975-08-01 00:00:00

abstract：:Differentiation commitment events are essential for the initiation of hemopoiesis and, in one form or another, occur continuously during adult hemopoiesis. The most studied type of differentiation commitment decision a hemopoietic cell can make involves the alternative choice of self-renewal versus the formation of pr...

journal_title：Journal of cellular physiology

authors： Metcalf D,Nicola NA,Robb L

更新日期：1997-11-01 00:00:00

abstract：:The present study was to investigate the effects and action mechanisms of digoxin and ouabain on steroidogenesis in human adrenocortical NCI-H295 cells. Administration of digoxin or ouabain for 24 h decreased the basal and angiotensin II (Ang II)-stimulated release of aldosterone by NCI-H295 cells. The conversions of ...

journal_title：Journal of cellular physiology

authors： Kau MM,Kan SF,Wang JR,Wang PS

更新日期：2005-12-01 00:00:00