Resistin induces monocyte-endothelial cell adhesion by increasing ICAM-1 and VCAM-1 expression in endothelial cells via p38MAPK-dependent pathway.

abstract：:A sialoglycopeptide (SGP), isolated and purified from bovine cerebral cortex cells, was studied in regard to early signal transduction events associated with the cell cycle. Previously shown to be a potent antagonist to a variety of mitogens, the SGP abrogated the ability of 12-O-tetradecanoylphorbol-13 acetate (TPA) ...

journal_title：Journal of cellular physiology

authors： Toole-Simms WE,Loder DK,Fattaey HK,Johnson TC

更新日期：1991-05-01 00:00:00

abstract：:Selective spermatozoa movement from storage of the oviduct to fertilization site is suggested to be a result of chemotaxis. In the present study, Natriuretic peptide precursor A (NPPA) induced sperm chemotaxis in capillaries and enhanced intracellular Ca(2+) level, both of which could be blocked by the Natriuretic Pep...

journal_title：Journal of cellular physiology

authors： Bian F,Mao G,Guo M,Mao G,Wang J,Li J,Han Y,Chen X,Zhang M,Xia G

更新日期：2012-05-01 00:00:00

abstract：:A method, based on the differing capacities of cells to adhere to a column of polyester fibres, has been described for separating human bone marrow cells into a nonadherent and an adherent fraction. The effect of this cell separation procedure on colony formation by erythroid progenitor cells was investigated. In cont...

journal_title：Journal of cellular physiology

authors： Aye MT

更新日期：1977-04-01 00:00:00

abstract：:Sterol regulatory element binding protein 1 (SREBP-1) is well-known as the master regulator of lipogenesis in rodents. Acyl-CoA synthetase short-chain family member 2 (ACSS2) plays a key role in lipogenesis by synthesizing acetyl-CoA from acetate for lipogenesis. ATP citrate lyase (ACLY) catalyzes the conversion of ci...

journal_title：Journal of cellular physiology

authors： Xu H,Luo J,Ma G,Zhang X,Yao D,Li M,Loor JJ

更新日期：2018-02-01 00:00:00

abstract：:This study aimed at investigating the expression and function of uracil nucleotide-sensitive receptors (P2Y(2), P2Y(4), and P2Y(6)) on osteogenic differentiation of human bone marrow stromal cells (BMSCs) in culture. Bone marrow specimens were obtained from postmenopausal female patients (68 ± 5 years old, n = 18) und...

journal_title：Journal of cellular physiology

authors： Noronha-Matos JB,Costa MA,Magalhães-Cardoso MT,Ferreirinha F,Pelletier J,Freitas R,Neves JM,Sévigny J,Correia-de-Sá P

更新日期：2012-06-01 00:00:00

abstract：:Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow function. Roles for 1,25-dihydroxyvitamin D3 (calcitriol) and all-trans...

journal_title：Journal of cellular physiology

authors： Piszczatowski RT,Rafferty BJ,Rozado A,Parziale JV,Lents NH

更新日期：2015-11-01 00:00:00

abstract：:In vitro incubation of hepatocytes acutely isolated from adult male rats leads to a rapid conversion of the adrenergic activation of glycogenolysis from an alpha 1-receptor (alpha 1AR) to a beta 2-receptor (beta 2AR) mediated response within 4 h. In order to understand the underlying mechanism, we examined time-depend...

journal_title：Journal of cellular physiology

authors： Ishac EJ,Lazar-Wesley E,Kunos G

更新日期：1992-07-01 00:00:00

abstract：:Estrogens mediate gene transcription and signaling of numerous cellular processes in a variety of tissues, including the bone, breast, and endometrium, through binding and activation of estrogen receptors (ERs). Estrogen-mediated ER agonist activity has shown benefit in conditions related to estrogen deficiency in wom...

journal_title：Journal of cellular physiology

authors： Komm BS,Mirkin S

更新日期：2013-07-01 00:00:00

abstract：:Normal human keratinocytes (NHK) were cultured in serum-free medium, containing low (0.1 mM) or high (2 mM) calcium, to obtain proliferating and differentiating cultures, respectively. Proteoglycan (PG) synthesis of proliferating and differentiating NHK was investigated. Cultures were labeled with 35S-sulfate, and the...

journal_title：Journal of cellular physiology

authors： Rahemtulla F,Moorer CM,Wille JJ Jr

更新日期：1989-07-01 00:00:00

abstract：:The predominant cyclooxygenase products of keratinocytes are prostaglandin (PG)E2 and PGF2 alpha with only trace amounts of PGI2 synthesis detected. When normal or immortal (NM1) keratinocytes were co-cultured with mitomycin C-treated 3T3 cells, increased synthesis of PGI2 was noted compared to mitomycin C-treated 3T3...

journal_title：Journal of cellular physiology

authors： Baden HP,Goldaber ML,Kvedar JC

更新日期：1992-02-01 00:00:00

abstract：:Epithelial cells are important components of the thymus microenvironment and are involved in thymocyte differentiation. The production and secretion of sulfated glycosaminoglycans by these cells grown in culture were investigated using labeling with radioactive 35S-Na2SO4 and 3H-glucosamine. The major glycosaminoglyca...

journal_title：Journal of cellular physiology

authors： Werneck CC,Oliveira-Dos-Santos AJ,Silva LC,Villa-Verde DM,Savino W,Mourão PA

更新日期：1999-01-01 00:00:00

abstract：:Tumors and multicellular tumor spheroids can develop gradients in oxygen concentration, glucose concentration, and extracellular pH as they grow. In order to calculate these gradients and assess their impact on tumor growth, it is necessary to quantify the effect of these variables on tumor cell metabolism and growth....

journal_title：Journal of cellular physiology

authors： Casciari JJ,Sotirchos SV,Sutherland RM

更新日期：1992-05-01 00:00:00

abstract：:Fibroblast growth factor-2 (FGF-2) stimulates periodontal regeneration by a broad spectrum of effects on periodontal ligament (PDL) cells, such as proliferation, migration, and production of extracellular matrix. A critical factor in the success of periodontal regeneration is the rapid resolution of inflammatory respo...

journal_title：Journal of cellular physiology

authors： Fujihara C,Kanai Y,Masumoto R,Kitagaki J,Matsumoto M,Yamada S,Kajikawa T,Murakami S

更新日期：2019-05-01 00:00:00

abstract：:The single-copy gene of human basic fibroblast growth factor (bFGF) encodes four co-expressed isoforms, with an apparent molecular weight (M(r)) of 24 kD, 22.5 kD, 22 kD, and 18 kD, co-translated from a single mRNA. As a tool for the study of the role exerted by the different bFGF isoforms in the biology of endothelia...

journal_title：Journal of cellular physiology

authors： Gualandris A,Urbinati C,Rusnati M,Ziche M,Presta M

更新日期：1994-10-01 00:00:00

abstract：:Core binding factor β (Cbfβ) is a partner protein of Runx family transcription factors with minimally characterized function in cartilage. Here we address the role of Cbfβ in cartilage by generating chondrocyte-specific Cbfβ-deficient mice (Cbfb(Δch/Δch) ) from Cbfb-floxed mice crossed with mice expressing Cre from th...

journal_title：Journal of cellular physiology

authors： Park NR,Lim KE,Han MS,Che X,Park CY,Kim JE,Taniuchi I,Bae SC,Choi JY

更新日期：2016-01-01 00:00:00

abstract：:With the long-range goals of elucidating the biochemical genetics and the phenotypic expression, both in vitro and in vivo, of mutator strains of mammalian cells, we have isolated and partially characterized a series of drug-resistant mutants from a subline a feeder-dependent parental mouse teratocarcinoma line (PSA-1...

journal_title：Journal of cellular physiology

authors： Aizawa S,Loeb LA,Martin GM

更新日期：1983-04-01 00:00:00

abstract：:The extent to which autolytic microbial enzymes are involved in the fate of microorganisms ingested by phagocytes has not been determined. It is known, however, that activation of degradative enzymes occurs during certain microbicidal events. We examined the possible role of the pneumococcal autolytic enzyme (an N-ace...

journal_title：Journal of cellular physiology

authors： Tomasz A,Beckerdite S,McDonnell M,Elsbach P

更新日期：1977-08-01 00:00:00

abstract：:Baculoviral IAP repeat containing 5 (BIRC5) gene encodes the important protein as survivin, a multifunctional protein, which is involved in cellular and molecular networks, progression of cell cycle, homeostasis, developmental morphogenesis, and apoptosis. The proximal BIRC5 promoter possesses specific binding sites f...

journal_title：Journal of cellular physiology

authors： Pahlavan Y,Kahroba H,Samadi N,Karimi A,Ansarin K,Khabbazi A

更新日期：2019-11-01 00:00:00

abstract：:Receptors for urokinase (uPA) and plasminogen provide a mechanism to direct the cellular activation of plasminogen. The regulation of these receptors is important for several macrophage functions. In these studies, the effect of transforming growth factor-beta 1 (TGF-beta 1) on uPA, uPA receptor, and plasminogen recep...

journal_title：Journal of cellular physiology

authors： Falcone DJ,McCaffrey TA,Mathew J,McAdam K,Borth W

更新日期：1995-08-01 00:00:00

abstract：:Pin1 is a peptidyl prolyl cis-trans isomerase that specifically binds to the phosphoserine-proline or phosphothreonine-proline motifs of numerous proteins. Previously, we reported that Pin1 deficiency resulted in defects in osteoblast differentiation during early bone development. In this study, we found that adult Pi...

journal_title：Journal of cellular physiology

authors： Yoon WJ,Islam R,Cho YD,Ryu KM,Shin HR,Woo KM,Baek JH,Ryoo HM

更新日期：2015-03-01 00:00:00

abstract：:KCNQ1 encodes a potassium voltage-gated channel and represents a susceptibility locus for type 2 diabetes mellitus (T2DM). Here, we explored the association between KCNQ1 polymorphisms and hypertension risk in individuals with T2DM, as well as the role of KCNQ1 in vascular smooth muscle cell contraction in vitro. To i...

journal_title：Journal of cellular physiology

authors： Huang KC,Li TM,Liu X,Chen JH,Chien WK,Shiao YT,Tsang H,Lin TH,Liao CC,Huang SM,Li JP,Lin CW,Lin JC,Lin CC,Lai CH,Cheng CF,Liang WM,Hung CH,Chen CC,Lin YJ,Tsai FJ

更新日期：2017-12-01 00:00:00

abstract：:This study was to explore a potential role of epithelium-derived cytokines in Th17 differentiation. Th17 induction was evaluated by murine CD4(+) T cells treated with different combinations of five inducing cytokines, or conditioned media of human corneal epithelial cells (HCECs) exposed to a variety of stimuli. Th17 ...

journal_title：Journal of cellular physiology

authors： Zheng X,Bian F,Ma P,De Paiva CS,Stern M,Pflugfelder SC,Li DQ

更新日期：2010-01-01 00:00:00

abstract：:Schizophrenia (SZ) is characterized by a high morbidity and disability rate and has gradually increased in rate and caused much burden. However, the pathogenesis of SZ is elusive and may include changes in the biological molecules in exosomes. In this study, we first compared the alterations of plasma exosomal circula...

journal_title：Journal of cellular physiology

authors： Tan G,Wang L,Liu Y,Zhang H,Feng W,Liu Z

更新日期：2021-01-01 00:00:00

abstract：:Diabetes mellitus (DM) induces bone deterioration, while mechanical stimulation promotes osteocyte-driven bone formation. We aimed to evaluate the interaction of acute exposure (24 h) to high glucose (HG) with both the pro-survival effect conferred to osteocytic MLO-Y4 cells and osteoblastic MC3T3-E1 cells by mechanic...

journal_title：Journal of cellular physiology

authors： Maycas M,Portolés MT,Matesanz MC,Buendía I,Linares J,Feito MJ,Arcos D,Vallet-Regí M,Plotkin LI,Esbrit P,Gortázar AR

更新日期：2017-12-01 00:00:00

abstract：:The permeability of human platelets to glycerol was determined at 37 degrees C, 25 degrees C, and 0 degrees C from the rate of change of cell volume after abrupt addition of 0.5 mol/liter glycerol in phosphate-buffered saline. Intracellular water volume was measured employing both tritiated water and a photometric met...

journal_title：Journal of cellular physiology

authors： Armitage WJ

更新日期：1986-07-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:Mutant forms of the p53 gene have been shown to cooperate with an activated ras gene in transforming primary cells in culture. The aberrant proteins encoded by p53 mutants are thought to act in a dominant negative manner in these assays. In vivo data, however, reveal that where p53 has undergone genetic change in tumo...

journal_title：Journal of cellular physiology

authors： Slingerland JM,Benchimol S

更新日期：1991-09-01 00:00:00

abstract：:Several organic cations are actively transported by proximal renal tubules by mediated processes across both the apical and basolateral cell membranes. In order to evaluate this transport system in a cultured renal epithelium, uptake of 3H-tetraethylammonium (TEA) across the apical membrane was measured in LLCPK1 cell...

journal_title：Journal of cellular physiology

authors： McKinney TD,DeLeon C,Speeg KV Jr

更新日期：1988-12-01 00:00:00

abstract：:Lymphocytes depleted of ATP by incubation in iodoacetate (IAA) and nitrogen (N2) lost K and gained Na. Isotopic Na exchange showed a fast fraction and a slower exponential fraction, the latter conventionally assumed to reflect surface membrane properties. The gain of cell Na was not accounted for by a decrease in 22Na...

journal_title：Journal of cellular physiology

authors： Negendank W,Shaller C

更新日期：1982-03-01 00:00:00

abstract：:Biology of glomerular visceral epithelial cells ("podocytes") and their role in inflammatory process remain obscure, partly because of the lack of well-differentiated podocyte cultures. We have established a human cell line by transfecting with a replication-defective SV40 plasmid (pSVHB1), a primary culture of podocy...

journal_title：Journal of cellular physiology

authors： Ardaillou N,Lelongt B,Turner N,Piedagnel R,Baudouin B,Estrade S,Cassingena R,Ronco PM

更新日期：1992-09-01 00:00:00