The effect of metabolic inhibition on ion contents and sodium exchange in human lymphocytes.

abstract：:Vitamin E, a dietary antioxidant, is presumed to be incorporated into the lipid bilayer of biological membranes to an extent proportional to the amount of polyunsaturated fatty acids or phospholipids in the membrane. In the present study we evaluated the distribution of incorporated polyunsaturated fatty acids (PUFA) ...

journal_title：Journal of cellular physiology

authors： Sekharam KM,Patel JM,Block ER

更新日期：1990-12-01 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP) (107-139), in contrast to the N-terminal fragment PTHrP (1-36), has been shown to interact with the vascular endothelial growth factor (VEGF) system to modulate human osteoblast differentiation. In this study, we evaluated whether this interaction might affect human osteobla...

journal_title：Journal of cellular physiology

authors： Alonso V,de Gortázar AR,Ardura JA,Andrade-Zapata I,Alvarez-Arroyo MV,Esbrit P

更新日期：2008-12-01 00:00:00

abstract：:The kinetic properties of partially purified ribonucleotide reductase from Chinese hamster ovary cells have been investigated. Double reciprocal plots of velocity against substrate concentration were found to be linear for three the substrates tested, and yielded apparent Km values of 0.12 mM for CDP, 0.14 mM for ADP ...

journal_title：Journal of cellular physiology

authors： Lewis WH,Wright JA

更新日期：1978-10-01 00:00:00

abstract：:The aim of this study was to identify the molecules and pathways involved in the cross-talk between meniscus and synovium that may play a critical role in osteoarthritis (OA) pathophysiology. Samples of synovium and meniscus were collected from patients with early and end-stage OA and cultured alone or cocultured. Cyt...

journal_title：Journal of cellular physiology

authors： Favero M,Belluzzi E,Trisolino G,Goldring MB,Goldring SR,Cigolotti A,Pozzuoli A,Ruggieri P,Ramonda R,Grigolo B,Punzi L,Olivotto E

更新日期：2019-07-01 00:00:00

abstract：:The mechanism of zinc (Zn) uptake by microvillous membrane vesicles prepared from human term placenta has been studied. The uptake was complex, with two processes being identified. In the first process, uptake was rapid, reaching equilibrium within 2 min, and was temperature dependent, with a Q10 of 1.5. Equilibrium Z...

journal_title：Journal of cellular physiology

authors： Aslam N,McArdle HJ

更新日期：1992-06-01 00:00:00

abstract：:The release of vasodilating substances from the vascular endothelium has been postulated to depend on a rise in the level of intracellular free calcium (Cai++). We measured Cai++ in intact monolayers of calf endothelial cells, grown in culture, that were loaded with the fluorescent calcium indicator quin 2. Fluorescen...

journal_title：Journal of cellular physiology

authors： Lückhoff A,Busse R

更新日期：1986-03-01 00:00:00

abstract：:Vascular endothelial cells receive proangiogenic or antiangiogenic signals from components of extracellular matrix (ECM) depending upon the situation and many molecular signals can have opposite effects in different vascular beds. Tissue inhibitor of metalloproteinase 1 is antiangiogenic in several tissues, but promot...

journal_title：Journal of cellular physiology

authors： Lima E Silva R,Kachi S,Akiyama H,Shen J,Aslam S,Yuan Gong Y,Khu NH,Hatara MC,Boutaud A,Peterson R,Campochiaro PA

更新日期：2006-07-01 00:00:00

abstract：:Synthesis of alpha- and beta-globin RNA in DMSO-induced Friend's erythroleukemia cells and synthesis of immunoglobulin gamma- and kappa-chain RNA, total RNA, 5S RNA, and tRNA in mouse myeloma cells (MPC-11) was inhibited by gamma-irradiation. For all RNA species, synthesis decreased nearly exponentially as a function ...

journal_title：Journal of cellular physiology

authors： Rodi CP,Sauerbier W

更新日期：1989-11-01 00:00:00

abstract：:The molecular weight of rat basic fibroblast growth factor is predicted to be 18 kDa when the amino acid sequence is read from the single AUG initiation codon found in the cDNA. DNA sequencing upstream of this AUG codon indicated, however, that there was an extended open reading frame. In vitro translation of the rat ...

journal_title：Journal of cellular physiology

authors： Powell PP,Klagsbrun M

更新日期：1991-08-01 00:00:00

abstract：:At the end of December 2019, a novel acute respiratory syndrome coronavirus 2 (SARS-CoV2) appeared as the third unheard of outbreak of human coronavirus infection in the 21st century. First, in Wuhan, China, the novel SARS-CoV2 was named by the World Health Organization (WHO), as 2019-nCOV (COVID-19), and spread extre...

journal_title：Journal of cellular physiology

authors： Tahmasebi S,Khosh E,Esmaeilzadeh A

更新日期：2020-12-01 00:00:00

abstract：:Estrogen-responsive genes often have an estrogen response element (ERE) positioned next to activator protein-1 (AP-1) binding sites. Considering that the interaction between ERE and AP-1 elements has been described for the modulation of bone-specific genes, we investigated the 17-beta-estradiol responsiveness and the ...

journal_title：Journal of cellular physiology

authors： Lambertini E,Tavanti E,Torreggiani E,Penolazzi L,Gambari R,Piva R

更新日期：2008-07-01 00:00:00

abstract：:Endothelial cell-derived growth factor (ECDGF) is a soluble mitogen secreted in vitro by bovine aortic endothelium. ECDGF is a mixture of at least two distinct heat-stable and trypsin-sensitive mitogens. Large amounts of mitogenic activity were found in lysates prepared from cultured endothelial cells. Other nonmitoge...

journal_title：Journal of cellular physiology

authors： Gajdusek CM,Schwartz SM

更新日期：1984-11-01 00:00:00

abstract：:We performed a network meta-analysis (NMA) to compare the short- and long-term efficacy of Gemcitabine, Gemcitabine + S-1 (tegafur), Gemcitabine + nab-paclitaxel, Gemcitabine + Capecitabine, Gemcitabine + Cisplatin, FOLFIRINOX (oxaliplatin + irinotecan + fluorouracil + leucovorin), Gemcitabine + oxaliplatin, Gemcitabi...

journal_title：Journal of cellular physiology

authors： Zhang SH,Liu GF,Li XF,Liu L,Yu SN

更新日期：2018-04-01 00:00:00

abstract：:Chemotherapy resistance is the major issue of choriocarcinoma. Apoptosis always is the ultimate outcome of chemotherapeutic drugs, which considered one of the reasons of resistance. We investigated the role of STAT3/NFIL3 signaling-inhibited apoptosis in chemotherapy resistance and whether Raddeanin A (RA) could be a ...

journal_title：Journal of cellular physiology

authors： Peng Z,Zhang C,Zhou W,Wu C,Zhang Y

更新日期：2018-07-01 00:00:00

abstract：:Hyperthermia has long been known as a radio-sensitizing agent that displays anti-tumor effects, and has been developed as a therapeutic application. The mechanisms of hyperthermia-induced radio-sensitization are highly associated with inhibition of DNA repair. Our investigations aimed to show how hyperthermia inactiva...

journal_title：Journal of cellular physiology

authors： Genet SC,Fujii Y,Maeda J,Kaneko M,Genet MD,Miyagawa K,Kato TA

更新日期：2013-07-01 00:00:00

abstract：:Intramedullary stabilization is frequently used to treat long bone fractures. Since implant removal can become technically very challenging with the potential to cause further tissue damage, biodegradable materials are emerging as alternative options. Magnesium (Mg)-based biodegradable implants have a controllable deg...

journal_title：Journal of cellular physiology

authors： Li D,Yu K,Xiao T,Dai Y,Liu L,Li H,Jiang D,Xiong L

更新日期：2019-11-01 00:00:00

abstract：:Interleukin (IL)-37 diminishes a variety of inflammatory responses through ligation to its receptor IL-1R8/Sigirr. Sigirr is a Toll like receptor/IL-1R family member. We have shown that Sigirr is not stable in response to IL-37 treatment. IL-37-induced Sigirr degradation is mediated by the ubiquitin-proteasome system,...

journal_title：Journal of cellular physiology

authors： Li L,Wei J,Suber TL,Ye Q,Miao J,Li S,Taleb SJ,Tran KC,Tamaskar AS,Zhao J,Zhao Y

更新日期：2021-01-05 00:00:00

abstract：:Cervical cancer is the fourth most frequent cancer in women worldwide. PDZ-binding kinase (PBK) is proven to promote the malignant behaviors of various carcinomas. However, its functional roles and oncogenic mechanisms in cervical cancer are poorly understood. In this study, we reported that PBK was highly expressed i...

journal_title：Journal of cellular physiology

authors： Ma H,Han F,Yan X,Qi G,Li Y,Li R,Yan S,Yuan C,Song K,Kong B

更新日期：2020-11-13 00:00:00

abstract：:During interphase, the centrosome concentrates cell stress response molecules, including chaperones and proteasomes, into a proteolytic center. However, whether the centrosome functions as proteolytic center during mitosis is not known. In this study, cultured mammalian cells were treated with the proteasome inhibitor...

journal_title：Journal of cellular physiology

authors： Ehrhardt AG,Sluder G

更新日期：2005-09-01 00:00:00

abstract：:17β-estradiol (E2) regulates diverse physiological effects including cell proliferation through the estrogen receptor α (ERα), which as a transcription factor drives gene transcription and as an extra-nuclear localized receptor triggers the membrane-dependent activation of diverse kinase cascades. E2 also modifies ERα...

journal_title：Journal of cellular physiology

authors： Leone S,Busonero C,Acconcia F

更新日期：2018-05-01 00:00:00

abstract：:The metabolome is a data-rich source of information concerning all the low-molecular-weight metabolites in a biofluid, which can indicate early biological changes to the host due to perturbations in metabolic pathways. Major changes can be seen after minor stimuli, which make it a valuable target for analysis. Due to ...

journal_title：Journal of cellular physiology

authors： Johnson CH,Gonzalez FJ

更新日期：2012-08-01 00:00:00

abstract：:Apoptosis constitutes a response of organisms to various physiological or pathological stimuli, and to different stresses. The ability of thermotolerance induced at a mild temperature of 40 degrees C to protect against activation of the apoptotic cascade by heat shock was investigated. When Chinese hamster ovary and h...

journal_title：Journal of cellular physiology

authors： Bettaieb A,Averill-Bates DA

更新日期：2005-10-01 00:00:00

abstract：:Emerging evidence have discovered that circular RNAs (circRNAs) may serve as diagnostic or tumor promising biomarkers. This study aimed to investigate how circular RNA ADAMTS14 (circADAMTS14) regulates microRNA-572/ regulator of calcineurin 1(miR-572/ RCAN1) in hepatocellular carcinoma (HCC). The expression profiles o...

journal_title：Journal of cellular physiology

authors： Song C,Li D,Liu H,Sun H,Liu Z,Zhang L,Hu Y

更新日期：2019-03-01 00:00:00

abstract：:The role of the plasma membrane potential (delta psi p) in the commitment to differentiation of murine erythroleukemia (MEL) cells has been studied by analyzing the ionic basis and the time course of this potential in the absence or the presence of different types of inducers. delta psi p was determined by measuring t...

journal_title：Journal of cellular physiology

authors： Arcangeli A,Ricupero L,Olivotto M

更新日期：1987-09-01 00:00:00

abstract：:Numerous reports have appeared on the occurrence of undefined protein factors in male reproductive fluids that promote motility of mature sperm and initiate forward motility in the immature (immotile) caput-epididymal sperm. This study reports for the first time purification to apparent homogeneity of a motility initi...

journal_title：Journal of cellular physiology

authors： Jaiswal BS,Das K,Saha S,Dungdung SR,Majumder GC

更新日期：2010-01-01 00:00:00

abstract：:Electrical stimulation (ES) has been shown to improve some of impairments after spinal cord injury (SCI), but the underlying mechanisms remain unclear. The Wnt signaling pathways and the endocannabinoid system appear to be modulated in response to SCI. This study aimed to investigate the effect of ES therapy on the ac...

journal_title：Journal of cellular physiology

authors： Ghorbani M,Shahabi P,Karimi P,Soltani-Zangbar H,Morshedi M,Bani S,Jafarzadehgharehziaaddin M,Sadeghzadeh-Oskouei B,Ahmadalipour A

更新日期：2020-12-01 00:00:00

abstract：:Nucleotides released from cells due to stress, injury or inflammation, induce mitogenic effects in monocytes via activation of P2Y(2) nucleotide receptors (P2Y(2)Rs). Here we show that P2Y(2) nucleotide receptors in U937 monocytic cells regulate the activation of extracellular signal-regulated kinases 1 and 2 (ERK 1/2...

journal_title：Journal of cellular physiology

authors： Chorna NE,Chevres M,Santos-Berrios C,Orellano EA,Erb L,González FA

更新日期：2007-05-01 00:00:00

abstract：:Wg/Wnts are paracrine and autocrine ligands that activate distinct signaling pathways while being internalized through surface receptors. Converging and contrasting views are shaping our understanding of whether, where, and how endocytosis may modulate Wnt signaling. We gather considerable amount of evidences to elabo...

journal_title：Journal of cellular physiology

authors： Feng Q,Gao N

更新日期：2015-06-01 00:00:00

abstract：:The stromal cell-derived factor-1 (SDF-1)/CXC receptor 4 (CXCR4) axis has been shown to play a role in colorectal cancer progression. In addition, the protease urokinase-type plasminogen activator (uPA) is an important factor in tumor cell invasion and metastasis. However, the mechanism by which SDF-1 mediates uPA exp...

journal_title：Journal of cellular physiology

authors： Huang WS,Chin CC,Chen CN,Kuo YH,Chen TC,Yu HR,Tung SY,Shen CH,Hsieh YY,Guo SE,Shi CS,Liu TJ,Kuo HC

更新日期：2012-03-01 00:00:00

abstract：:Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of this study was to dete...

journal_title：Journal of cellular physiology

authors： Redmond EM,Cahill PA,Hodges R,Zhang S,Sitzmann JV

更新日期：1996-03-01 00:00:00