LOC103691336/miR-138-5p/BMPR2 axis modulates Mg-mediated osteogenic differentiation in rat femoral fracture model and rat primary bone marrow stromal cells.

abstract：:Proteolytic cleavage of extracellular matrix (ECM) is a critical feature of tumor cell invasion, and affects cancer cell growth, differentiation, apoptosis, and migration. Malignant cells secrete most proteases as inactive proenzymes that undergo proteolytic cleavage for activation, and proteolytic activity is elevate...

journal_title：Journal of cellular physiology

authors： Kusick S,Bertram H,Oberleithner H,Ludwig T

更新日期：2005-09-01 00:00:00

abstract：:We demonstrated previously that in serum-starved MCF-7 breast cancer cell line, Ang II increased Na+/K+ATPase activity and activated the protein kinase C zeta (PKC-zeta) (Muscella et al., 2002 J Endocrinol 173:315-323; 2003 J Cell Physiol 197:61-68.). The aim of the present study was to investigate the modulation of t...

journal_title：Journal of cellular physiology

authors： Muscella A,Storelli C,Marsigliante S

更新日期：2005-11-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:The periderm is a flat layer of epithelium created during embryonic development. During palatogenesis, the periderm forms a protective layer against premature adhesion of the oral epithelia, including the palate. However, the periderm must be removed in order for the medial edge epithelia (MEE) to properly adhere and ...

journal_title：Journal of cellular physiology

authors： Hu L,Liu J,Li Z,Ozturk F,Gurumurthy C,Romano RA,Sinha S,Nawshad A

更新日期：2015-06-01 00:00:00

abstract：:Experiments were conducted to determine the extent and variability of collagen degradation in human fetal lung fibroblasts. Cells were incubated with [14C]proline, and degradation was measured by determining the hydroxy[14C]proline in a low molecular weight fraction relative to total hydroxy[14C]proline. Average (basa...

journal_title：Journal of cellular physiology

authors： Bienkowski RS

更新日期：1984-10-01 00:00:00

abstract：:Incubation of primary cultures of parenchymal hepatocytes in a conditioned medium (CM), collected over the first 3 h of serum-free rat hepatocyte culture (CM(0-3)), induces a time dependent increase of the frequency of apoptotic cells which is accompanied by prominent changes of cell morphology. Short-term treatment w...

journal_title：Journal of cellular physiology

authors： Bresgen N,Rolinek R,Hochleitner E,Lottspeich F,Eckl PM

更新日期：2004-03-01 00:00:00

abstract：:Optimal stimulation of signal transduction and biological functions by IGF-I in porcine smooth muscle cells (pSMC) requires ligand occupancy of the alphaVbeta3 integrin. Binding of heparin-binding domain (HBD) of vitronectin (VN) to the cysteine loop (C-loop) region of beta3 is required for pSMC to respond optimally t...

journal_title：Journal of cellular physiology

authors： Xi G,Maile LA,Yoo SE,Clemmons DR

更新日期：2008-02-01 00:00:00

abstract：:Pur-alpha is an essential protein for postnatal brain development which localizes specifically to dendrites where it plays a role in the translation of neuronal RNA. Mice lacking Pur-alpha display decreased neuronogenesis and impaired neuronal differentiation. Here we examined two Rho GTPases, Rac1 and RhoA, which pla...

journal_title：Journal of cellular physiology

authors： Mishra M,Del Valle L,Otte J,Darbinian N,Gordon J

更新日期：2013-01-01 00:00:00

abstract：:Cardiac fibroblast (CF) differentiation to myofibroblasts expressing α-smooth muscle actin (α-SMA) plays a key role in cardiac fibrosis. Therefore, a study of the mechanism regulating α-SMA expression is a means to understanding the mechanism of fibroblast differentiation and cardiac fibrosis. Previous studies have sh...

journal_title：Journal of cellular physiology

authors： He Y,Ling S,Sun Y,Sheng Z,Chen Z,Pan X,Ma G

更新日期：2019-05-01 00:00:00

abstract：:Cell-extracellular matrix interaction plays a major role in maintaining the structural integrity of connective tissues and sensing changes in the biomechanical environment of cells. Collagen VI is a widely expressed non-fibrillar collagen, which regulates tissues homeostasis. The objective of the present investigation...

journal_title：Journal of cellular physiology

authors： Sardone F,Traina F,Tagliavini F,Pellegrini C,Merlini L,Squarzoni S,Santi S,Neri S,Faldini C,Maraldi N,Sabatelli P

更新日期：2014-07-01 00:00:00

abstract：:CSF-1 is a hemopoietic growth factor that specifically regulates the survival, proliferation, and differentiation of mononuclear phagocytic cells. Populations of adherent bone marrow-derived macrophages (BMM) devoid of CSF-1 producing cells were used to study regulation by CSF-1 of macrophage entry into S phase. More ...

journal_title：Journal of cellular physiology

authors： Tushinski RJ,Stanley ER

更新日期：1985-02-01 00:00:00

abstract：:We have analyzed the regulation of transcription of integrated SV40 DNA and of five cellular genes during the cell cycle of two lines of SV40 transformed mouse 3T3 cells. These cells (ts SV3T3) are temperature sensitive for the expression of the transformed phenotype and at the nonpermissive temperature (39 degrees C)...

journal_title：Journal of cellular physiology

authors： La Bella F,Brown EH,Basilico C

更新日期：1983-10-01 00:00:00

abstract：:Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein of 38 kDa in size, p38SJ, from a callus culture of Hypericum perforat...

journal_title：Journal of cellular physiology

authors： Amini S,Merabova N,Khalili K,Darbinian N

更新日期：2009-12-01 00:00:00

abstract：:Intestinal cells were isolated by a combination of mechanical and enzymatic means, and their calcium uptake was assayed by a rapid filtration procedure. Calcium uptake was a time- and concentration-dependent process that was markedly elevated at 25 and 37 degrees C, as compared to 0 degree C. Cells isolated from rat d...

journal_title：Journal of cellular physiology

authors： Bronner F,Pansu D,Bosshard A,Lipton JH

更新日期：1983-09-01 00:00:00

abstract：:We compared the effects of endothelial-synthesized matrix and purified matrix molecules on pericyte (PC) and aortic smooth muscle cell (SMC) growth, heparin sensitivity, and contractile phenotype in vitro. When PC are plated on endothelial-synthesized (EC) matrix, cell number is, on average, 3.1-fold higher than ident...

journal_title：Journal of cellular physiology

authors： Newcomb PM,Herman IM

更新日期：1993-05-01 00:00:00

abstract：:The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the glucagon/vasoactive intestinal peptide (VIP) superfamily, stimulates cyclic AMP accumulation initiating a variety of biological processes such as: neurotropic actions, immune and pituitary function, learning and memory, catech...

journal_title：Journal of cellular physiology

authors： Nagata A,Tanaka T,Minezawa A,Poyurovsky M,Mayama T,Suzuki S,Hashimoto N,Yoshida T,Suyama K,Miyata A,Hosokawa H,Nakayama T,Tatsuno I

更新日期：2009-10-01 00:00:00

abstract：:While dental mesenchymal stem cells are well-studied, the origin of these cells is still unclear. Bone marrow-derived cells (BMDCs) have the potential to engraft into several tissues after injury, but whether they can become dental tissue-specific progenitor cells under normal conditions and the relationship of these ...

journal_title：Journal of cellular physiology

authors： Zhou J,Shi S,Shi Y,Xie H,Chen L,He Y,Guo W,Wen L,Jin Y

更新日期：2011-08-01 00:00:00

abstract：:The matricellular protein periostin is strongly expressed in collagen-rich connective tissues such as periodontal ligaments (PDLs), skeletal muscle, adipose tissue, tendons, skin, and bone. It is prominent in tumorigenesis, angiogenesis, and cardiac repair. It is localized in the periosteum and PDL, where it is seen i...

journal_title：Journal of cellular physiology

authors： Romanos GE,Asnani KP,Hingorani D,Deshmukh VL

更新日期：2014-01-01 00:00:00

abstract：:MCOLN1 encodes mucolipin-1 (TRPML1), a member of the transient receptor potential TRPML subfamily of channel proteins. Mutations in MCOLN1 cause mucolipidosis-type IV (MLIV), a lysosomal storage disorder characterized by severe neurologic, ophthalmologic, and gastrointestinal abnormalities. Along with TRPML1, there ar...

journal_title：Journal of cellular physiology

authors： Curcio-Morelli C,Zhang P,Venugopal B,Charles FA,Browning MF,Cantiello HF,Slaugenhaupt SA

更新日期：2010-02-01 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP) (107-139), in contrast to the N-terminal fragment PTHrP (1-36), has been shown to interact with the vascular endothelial growth factor (VEGF) system to modulate human osteoblast differentiation. In this study, we evaluated whether this interaction might affect human osteobla...

journal_title：Journal of cellular physiology

authors： Alonso V,de Gortázar AR,Ardura JA,Andrade-Zapata I,Alvarez-Arroyo MV,Esbrit P

更新日期：2008-12-01 00:00:00

abstract：:Wnt/β-catenin signaling pathway plays a crucial role in diabetic cardiomyopathy (DCM), thus we aimed at investigating the effect of one therapeutic approach with resveratrol (RSV) given systemically and combined treatment of RSV with mesenchymal stem cells (MSCs) that was either RSV-preconditioned or not on Wnt/β-cate...

journal_title：Journal of cellular physiology

authors： ShamsEldeen AM,Ashour H,Shoukry HS,Fadel M,Kamar SS,Aabdelbaset M,Rashed LA,Ammar HI

更新日期：2019-07-01 00:00:00

abstract：:Ack1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. It integrates signals from plethora of ligand-activated receptor tyrosine kinases (RTKs), for example, MERTK, EGFR, HER2, PDGFR and insulin receptor to initiate intra...

journal_title：Journal of cellular physiology

authors： Mahajan K,Mahajan NP

更新日期：2010-08-01 00:00:00

abstract：:This study is performed to examine the impacts of microRNA-218 (miR-218) on cardiac microvascular endothelial cells (CMECs) injury induced by coronary artery disease (CAD). Reverse-transcription quantitative polymerase chain reaction (RT-qPCR) was applied for detecting miR-218 expression in serum of patients with CAD ...

journal_title：Journal of cellular physiology

authors： Gao W,Cui H,Li Q,Zhong H,Yu J,Li P,He X

更新日期：2020-03-01 00:00:00

abstract：:Short term, carrier mediated transport of D-glucose, L-leucine and L-lysine by guinea pig peritoneal macrophages was characterized. Analysis of the amino acid transport demonstrated two-limbed double reciprocal plots suggesting two transport systems for each amino acid. The low concentration limb of the curves establi...

journal_title：Journal of cellular physiology

authors： Straus DC,Imhoff JG,Bonventre PF

更新日期：1977-10-01 00:00:00

abstract：:To evaluate the growth-inhibitory properties of the potent multi-kinase antagonist Regorafenib (Fluoro-Sorafenib), which was synthesized as a more potent Sorafenib, a Raf inhibitor and to determine whether similar mechanisms were involved, human hepatoma cell lines were grown in the presence or absence of Regorafanib ...

journal_title：Journal of cellular physiology

authors： Carr BI,Cavallini A,Lippolis C,D'Alessandro R,Messa C,Refolo MG,Tafaro A

更新日期：2013-02-01 00:00:00

abstract：:Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with endothelial gap ju...

journal_title：Journal of cellular physiology

authors： Zhang YW,Morita I,Nishida M,Murota SI

更新日期：1999-09-01 00:00:00

abstract：:Activation of hepatic progenitor cells (HPCs) is commonly observed in chronic liver disease and Wnt/β-catenin signaling plays a crucial role in the expansion of HPCs. However, the molecular mechanisms that regulate the activation of Wnt/β-catenin signaling in the liver, especially in HPCs, remain largely elusive. Here...

journal_title：Journal of cellular physiology

authors： Ding ZY,Liang HF,Jin GN,Chen WX,Wang W,Datta PK,Zhang MZ,Zhang B,Chen XP

更新日期：2014-05-01 00:00:00

abstract：:Monocytes are recruited to the material surface of an implanted biomedical device recognizing it as a foreign body. Differentiation into macrophages subsequently occurs followed by fusion to form foreign body giant cells (FBGCs). Consequently, implants can become degraded, cause chronic inflammation or become isolated...

journal_title：Journal of cellular physiology

authors： Matheson LA,Santerre JP,Labow RS

更新日期：2004-04-01 00:00:00

abstract：:Pharmacogenomics, toxicogenomics, and small RNA expression analysis are three of the most active research topics in the biological, biomedical, pharmaceutical, and toxicological fields. All of these studies are based on gene expression analysis, which requires reference genes to reduce the variations derived from diff...

journal_title：Journal of cellular physiology

authors： Chen D,Pan X,Xiao P,Farwell MA,Zhang B

更新日期：2011-10-01 00:00:00

abstract：:Cultured rat embryo cells were stimulated to rapidly release a small group of proteins that included several heat-shock proteins (hsp110, hsp71, hscp73) and nonmuscle actin. The extracellular proteins were analyzed by two-dimensional polyacrylamide gel electrophoresis. Heat-shocked cells released the same set of prote...

journal_title：Journal of cellular physiology

authors： Hightower LE,Guidon PT Jr

更新日期：1989-02-01 00:00:00