The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1.

abstract：:The purpose of this study was to delineate the traffic patterns of EGF and EGF receptors (EGFR) in primary cultured acinar epithelial cells from rabbit lacrimal glands. Uptake of [(125)I]-EGF exhibited saturable and non-saturable, temperature-dependent components, suggesting both receptor-mediated and fluid phase endo...

journal_title：Journal of cellular physiology

authors： Xie J,Qian L,Wang Y,Rose CM,Yang T,Nakamura T,Hamm-Alvarez SF,Mircheff AK

更新日期：2004-04-01 00:00:00

abstract：:To reduce embryonic losses in domestic animals for economic production of livestock meat and milk, chemokines and their receptors are required for proper implantation and placentation during early pregnancy. In this study, we investigated the effects of C-C-motif chemokine ligand 23 (CCL23) on the proliferation of bov...

journal_title：Journal of cellular physiology

authors： Lim W,Bae H,Bazer FW,Song G

更新日期：2018-04-01 00:00:00

abstract：:Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in these pathologies suggest its poten...

journal_title：Journal of cellular physiology

authors： Birukova AA,Zagranichnaya T,Alekseeva E,Bokoch GM,Birukov KG

更新日期：2008-06-01 00:00:00

abstract：:Breast cancer stem cells (BCSCs) are competent to initiate tumor formation and growth and refractory to conventional therapies. Consequently BCSCs are implicated in tumor recurrence. Many signaling cascades associated with BCSCs are critical for epithelial-to-mesenchymal transition (EMT). We developed a model system t...

journal_title：Journal of cellular physiology

authors： Fritz AJ,Hong D,Boyd J,Kost J,Finstaad KH,Fitzgerald MP,Hanna S,Abuarqoub AH,Malik M,Bushweller J,Tye C,Ghule P,Gordon J,Frietze S,Zaidi SK,Lian JB,Stein JL,Stein GS

更新日期：2020-10-01 00:00:00

abstract：:We previously revealed that epithelial-to-mesenchymal transition (EMT) was mediated by ΔNp63β, a splicing variant of ΔNp63, in oral squamous cell carcinoma (OSCC). Recent studies have highlighted the involvement of microRNA (miRNA) in EMT of cancer cells, though the mechanism remains unclear. To identify miRNAs respon...

journal_title：Journal of cellular physiology

authors： Hashiguchi Y,Kawano S,Goto Y,Yasuda K,Kaneko N,Sakamoto T,Matsubara R,Jinno T,Maruse Y,Tanaka H,Morioka M,Hattori T,Tanaka S,Kiyoshima T,Nakamura S

更新日期：2018-10-01 00:00:00

abstract：:Rat thyroid follicles in both the normal and the inverted configuration have been cultured in suspension. It has been found that normal follicles (i.e., those having a structural organization similar to the follicles in vivo) express most functional properties of the thyroid gland. They trap iodide, synthesize, secret...

journal_title：Journal of cellular physiology

authors： Tacchetti C,Zurzolo C,Monticelli A,Nitsch L

更新日期：1986-01-01 00:00:00

abstract：:Cyclosporine A (CyA) is a powerful nonsteroidal immunosuppressive agent used to prevent graft rejection of organ and bone marrow transplants. A major side effect observed can be attributed to the fibroblast and its functions: proliferation of fibroblasts and formation of fibrotic tissue in the gingiva (fibrous hyperpl...

journal_title：Journal of cellular physiology

authors： Willershausen-Zönnchen B,Lemmen C,Schumacher U

更新日期：1992-08-01 00:00:00

abstract：:The progression of cancer is often associated with genomic instability, which may develop as a result of compromised defense mechanisms responsible for the maintenance of chromosomal integrity. These include defects in telomere preservation, chromosomal segregation, and DNA repair. In this review, we discuss molecular...

journal_title：Journal of cellular physiology

authors： Reiss K,Khalili K,Giordano A,Trojanek J

更新日期：2006-02-01 00:00:00

abstract：:BAG3 is a member of human BAG (Bcl-2-associated athanogene) proteins and plays a role in apoptosis, cell adhesion, cytoskeleton remodeling, and autophagy. The aim of this study was to evaluate BAG3 levels in healthy subjects, hypertensive patients, and hypertensive diabetic patients. We enrolled 209 Caucasian adults, ...

journal_title：Journal of cellular physiology

authors： Derosa G,Maffioli P,Rosati A,M M,Basile A,D'Angelo A,Romano D,Sahebkar A,Falco A,Turco MC

更新日期：2018-03-01 00:00:00

abstract：:Activation of the epidermal growth factor receptor (EGFR) has been shown to occur by ligand-dependent and ligand-independent mechanisms. Different molecular mechanisms have been found to be responsible for ligand-independent receptor transactivation. Here, we show that hyperosmolar concentrations of sorbitol activate ...

journal_title：Journal of cellular physiology

authors： Cheng H,Kartenbeck J,Kabsch K,Mao X,Marqués M,Alonso A

更新日期：2002-08-01 00:00:00

abstract：:Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need to further investigate the signaling pathways that mediate CH in order to identify novel therapeut...

journal_title：Journal of cellular physiology

authors： Riaz S,Zeidan A,Mraiche F

更新日期：2017-12-01 00:00:00

abstract：:Osteoclasts are multinucleated cells formed by fusion of preosteoclasts (POCs) derived from cells of the monocyte/macrophage lineage. We have reported a culture system that supports the formation of POCs from stroma-depleted rat bone marrow cells. Global gene expression analysis of this culture system identified genes...

journal_title：Journal of cellular physiology

authors： Funakubo N,Xu X,Kukita T,Nakamura S,Miyamoto H,Kukita A

更新日期：2018-04-01 00:00:00

abstract：:There is evidence that cadmium can initiate carcinogenesis. However, the underlying mechanisms remain unknown. There is also evidence that moderate centrosome amplification can initiate tumorigenesis. The present study investigated whether cadmium could trigger cell centrosome amplification, and examined the underlyin...

journal_title：Journal of cellular physiology

authors： Zhang RK,Wang P,Lu YC,Lang L,Wang L,Lee SC

更新日期：2019-08-01 00:00:00

abstract：:Di- and tripeptides and peptide mimetics such as beta-lactam antibiotics are efficiently reabsorbed from the tubular lumen by a high-affinity peptide transporter. We have recently identified and characterized this H+-coupled high-affinity peptide transport system in the porcine proximal tubular cell line LLC-PK1. Here...

journal_title：Journal of cellular physiology

authors： Wenzel U,Diehl D,Herget M,Kuntz S,Daniel H

更新日期：1999-03-01 00:00:00

abstract：:Our objective was to establish the existence of intercellular communication through gap junctions in synovial lining cells and in primary and passaged cultures of human synovial cells. Communication between cells was assessed using the nystatin perforated-patch method, fluorescent dye transfer, immunochemistry, transm...

journal_title：Journal of cellular physiology

authors： Kolomytkin OV,Marino AA,Sadasivan KK,Meek WD,Wolf RE,Hall V,McCarthy KJ,Albright JA

更新日期：2000-07-01 00:00:00

abstract：:Mouse L-929 cells were subjected to increasing concentrations of sorbitol, which remove cell water and reduce volume osmotically. The rate of lactate production from glucose was significantly higher in osmotically perturbed cells than in controls, both in monolayers and in suspensions. L cells can apparently use sorbi...

journal_title：Journal of cellular physiology

authors： Clegg JS,Jackson SA,Fendl K

更新日期：1990-02-01 00:00:00

abstract：:Heat shock factors (HSFs) are the main transcriptional regulators of the stress-induced expression of heat shock protein genes. HSF2, which is one of the HSFs, is activated during differentiation and development but it is unclear how they regulate during cellular processes. Here, we examined the role of HSF4a on the r...

journal_title：Journal of cellular physiology

authors： Kim SA,Yoon JH,Ahn SG

更新日期：2012-01-01 00:00:00

abstract：:Heart failure is a major cause of death throughout the world. Hyperthyroidism has been shown to induce cardiac hypertrophy, which is a contributing factor to heart failure. However, the mechanism underling effect of thyroid hormone is not completely clear. The present study investigates the role of peroxisome prolifer...

journal_title：Journal of cellular physiology

authors： Xu W,Hou D,Jiang X,Lu Z,Guo T,Liu Y,Wang D,Zen K,Yu B,Zhang CY

更新日期：2012-09-01 00:00:00

abstract：:Circular RNAs (circRNAs) play critical roles in signal transduction during cell proliferation, differentiation, and apoptosis in a posttranscriptional manner. Recently, circRNAs have been proved to be a large class of animal RNAs with regulatory potency. However, whether circRNAs can respond to mechanical force (MF) a...

journal_title：Journal of cellular physiology

authors： Wang H,Feng C,Jin Y,Tan W,Wei F

更新日期：2019-07-01 00:00:00

abstract：:A cloned human hepatoma cell line (Li-7A), possessing epidermal growth factor (EGF) receptors numbering in the range of 10-20 pmol/10(6) cells, was inhibited in its growth by EGF as well as an antagonist monoclonal antibody (MoAb) to the EGF receptor. The mode of action of the two ligands of EGF receptors appeared to ...

journal_title：Journal of cellular physiology

authors： Knowles AF

更新日期：1988-01-01 00:00:00

abstract：:The myelin basic protein (MBP) gene contains sequences located upstream of its transcription start site which play a key role in glial-specific transcription of the MBP promoter. Earlier analysis of the 320 bp upstream regulatory sequence of MBP has revealed multiple cis-acting regulatory motifs which differentially r...

journal_title：Journal of cellular physiology

authors： Haque NS,Haas S,Knobler RL,Khalili K

更新日期：1995-05-01 00:00:00

abstract：:1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) and the vitamin D receptor (VDR) have been reported to have an important role in the regulation of innate immunity. We earlier reported that the antimicrobial peptide cathelicidin is induced by 1,25(OH)2D3 in normal human bronchial epithelial cells with a resultant increase in an...

journal_title：Journal of cellular physiology

authors： Dhawan P,Wei R,Sun C,Gombart AF,Koeffler HP,Diamond G,Christakos S

更新日期：2015-02-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) have been found to be tightly correlated with the progression of prostate cancer (PC). In this study, we investigated the effects of an SDF-1α/CXCR4 inhibitor, AMD3100, on cell progression and metastasis potential of human PC cells. Human PC ce...

journal_title：Journal of cellular physiology

authors： Zhu WB,Zhao ZF,Zhou X

更新日期：2019-07-01 00:00:00

abstract：:Cervical cancer is the fourth most frequent cancer in women worldwide. PDZ-binding kinase (PBK) is proven to promote the malignant behaviors of various carcinomas. However, its functional roles and oncogenic mechanisms in cervical cancer are poorly understood. In this study, we reported that PBK was highly expressed i...

journal_title：Journal of cellular physiology

authors： Ma H,Han F,Yan X,Qi G,Li Y,Li R,Yan S,Yuan C,Song K,Kong B

更新日期：2020-11-13 00:00:00

abstract：:The activation/adaptive responses of human monocytes exposed to Bordetella pertussis parental or mutant strains were evaluated and correlated to the expression of two bacterial toxins: adenylate cyclase-hemolysin and pertussis toxin. The marked rise in intracellular cyclic adenosine monophosphate (cAMP) observed in mo...

journal_title：Journal of cellular physiology

authors： Njamkepo E,Pinot F,François D,Guiso N,Polla BS,Bachelet M

更新日期：2000-04-01 00:00:00

abstract：:The mammalian olfactory system is a physiologically plastic region of the brain with the potential to support implanted stem cells. We performed direct injection of lineage-negative (lin-neg), green fluorescent protein-positive (GFP+) bone marrow cells into the olfactory bulb to assess cell survival and motility withi...

journal_title：Journal of cellular physiology

authors： Moore BE,Colvin GA,Dooner MS,Quesenberry PJ

更新日期：2005-01-01 00:00:00

abstract：:As a typical hibernator, the Daurian ground squirrel (Spermophilus dauricus) spends considerable time in a state of reduced activity with prolonged fasting. Despite this, they experience little muscle atrophy and have thus become an interesting anti-disuse muscle atrophy model. The IKKβ/NF-κB signaling pathway is sign...

journal_title：Journal of cellular physiology

authors： Wei Y,Gong L,Fu W,Xu S,Wang Z,Zhang J,Ning E,Chang H,Wang H,Gao Y

更新日期：2018-11-01 00:00:00

abstract：:Cancer is one of the common lifestyle diseases and is considered to be the leading cause of death worldwide. Epstein-Barr virus (EBV)-infected individuals remain asymptomatic; but under certain stress conditions, EBV may lead to the development of cancers such as Burkitt's and Hodgkin's lymphoma and nasopharyngeal car...

journal_title：Journal of cellular physiology

authors： Ojha R,Nandani R,Prajapati VK

更新日期：2019-05-01 00:00:00

abstract：:This study was to explore a potential role of epithelium-derived cytokines in Th17 differentiation. Th17 induction was evaluated by murine CD4(+) T cells treated with different combinations of five inducing cytokines, or conditioned media of human corneal epithelial cells (HCECs) exposed to a variety of stimuli. Th17 ...

journal_title：Journal of cellular physiology

authors： Zheng X,Bian F,Ma P,De Paiva CS,Stern M,Pflugfelder SC,Li DQ

更新日期：2010-01-01 00:00:00

abstract：:The molecular weight of rat basic fibroblast growth factor is predicted to be 18 kDa when the amino acid sequence is read from the single AUG initiation codon found in the cDNA. DNA sequencing upstream of this AUG codon indicated, however, that there was an extended open reading frame. In vitro translation of the rat ...

journal_title：Journal of cellular physiology

authors： Powell PP,Klagsbrun M

更新日期：1991-08-01 00:00:00