Antibodies reacting to mimotopes of Simian virus 40 large T antigen, the viral oncoprotein, in sera from children.

abstract：:It was the goal of this study to determine whether during long-term quiescence WI-38 cells gradually lose labile components which then need to be resynthesized before a stimulated cell can progress through G-1 and enter S. The metabolic and molecular status of WI-38 cells was systematically analyzed as they entered an...

journal_title：Journal of cellular physiology

authors： Owen TA,Carter R,Whitman MM,Soprano DR,Soprano KJ

更新日期：1990-01-01 00:00:00

abstract：:In culture, B16/C3 murine melanoma cells grown in the presence of serum undergo melanogenesis at a specific time after plating. At this time, melanin is synthesized intracellularly and then secreted into the extracellular culture fluid. We have found that melanin secretion is dependent on the presence of serum in the ...

journal_title：Journal of cellular physiology

authors： Laskin JD,Piccinini L,Engelhardt DL,Weinstein IB

更新日期：1982-12-01 00:00:00

abstract：:32D cells are murine myeloid cells that grow indefinitely in Interleukin-3 (IL-3). In these cells, the type 1 insulin-like growth factor (IGF-I) and granulocytic-colony stimulating factor (G-CSF) induce differentiation to granulocytes. 32D cells do not express insulin receptor substrate-1 (IRS-1) or IRS-2, docking pro...

journal_title：Journal of cellular physiology

authors： Shi B,Prisco M,Calin G,Liu CG,Russo G,Giordano A,Baserga R

更新日期：2006-06-01 00:00:00

abstract：:Experiments were carried out to test the hypothesis that cell spreading and phagocytosis are similar cell responses to different-sized substrata. The following morphological and biochemical studies provided evidence for this supposition. Cells phagocytosed 1.09-micron and 5.7-micron latex beads, but were unable to com...

journal_title：Journal of cellular physiology

authors： Grinnell F

更新日期：1984-04-01 00:00:00

abstract：:Osteoporosis is a class of metabolic bone disease caused by complexed ramifications. Overactivation of osteoclasts due to a sudden decreased estrogen level plays a pivotal role for postmenopausal women suffering from osteoporosis. Therefore, inhibiting osteoclast formation and function has become a major direction for...

journal_title：Journal of cellular physiology

authors： Li K,Xiao Y,Wang Z,Fu F,Shao S,Song F,Zhao J,Lin X,Liu Q,Xu J

更新日期：2019-02-27 00:00:00

abstract：:The multiplication rate of sparse cultures of chick embryo cells is only slightly lower at pH 6.9 than at pH 7.4. There is, however, a marked reduction in the multiplication rate of the pH 6.9 cultures before they reach confluency. Cultures at pH 7.4 continue to multiply beyond confluency with only a slight decrease i...

journal_title：Journal of cellular physiology

authors： Fodge DW,Rubin H

更新日期：1975-06-01 00:00:00

abstract：:Nerve-evoked contractile activity in skeletal muscle regulates transcript and protein levels of many metabolic genes in a coordinate fashion, including the muscle isozyme of glycogen phosphorylase (MGP). Cellular signaling mechanisms mediating the activity-dependent modulation of MGP transcript levels were investigate...

journal_title：Journal of cellular physiology

authors： Vali S,Carlsen R,Pessah I,Gorin F

更新日期：2000-11-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS), characterized by acute hypoxic respiratory dysfunction or failure, is a manifestation of multiple organ failure in the lung, and the most common risk factor is sepsis. We previously showed that blocking α2 -adrenoceptor (α2 -AR) could attenuate lung injury induced by endotox...

journal_title：Journal of cellular physiology

authors： Cong Z,Li D,Tao Y,Lv X,Zhu X

更新日期：2020-10-01 00:00:00

abstract：:We recently reported that peptidoglycan (PGN), a cell wall component of the Gram-positive bacterium, induces NF-κB activation and microglia activation. However, PGN-regulated AP-1 activation and cytokine expression in microglia remains unclear. This study investigated how PGN influences the signaling pathway involved ...

journal_title：Journal of cellular physiology

authors： Lin HY,Tang CH,Chen JH,Chuang JY,Huang SM,Tan TW,Lai CH,Lu DY

更新日期：2011-06-01 00:00:00

abstract：:Recent evidence has verified the cardioprotective actions of irisin in different diseases models. However, the beneficial action of irisin on hypoxia-reoxygenation (HR) injury under high glucose stress has not been described. Herein our research investigated the influence of irisin on HR-triggered cardiomyocyte death ...

journal_title：Journal of cellular physiology

authors： Fan J,Zhu Q,Wu Z,Ding J,Qin S,Liu H,Miao P

更新日期：2020-02-01 00:00:00

abstract：:Binge drinking is associated with increased cardiac autophagy, and often triggers heart injury. Given the essential role of autophagy in various cardiac diseases, this study was designed to investigate the role of autophagy in ethanol-induced cardiac injury and the underlying mechanism. Our study showed that ethanol e...

journal_title：Journal of cellular physiology

authors： Zhu Z,Huang Y,Lv L,Tao Y,Shao M,Zhao C,Xue M,Sun J,Niu C,Wang Y,Kim S,Cong W,Mao W,Jin L

更新日期：2018-02-01 00:00:00

abstract：:Despite remarkable progress in polychemotherapy protocols, pediatric B-cell acute lymphoblastic leukemia (B-ALL) remains fatal in around 20% of cases. Hence, novel targeted therapies are needed for patients with poor prognosis. Glucocorticoids (GCs) are drugs commonly administrated for B-ALL treatment. Activation of t...

journal_title：Journal of cellular physiology

authors： Evangelisti C,Cappellini A,Oliveira M,Fragoso R,Barata JT,Bertaina A,Locatelli F,Simioni C,Neri LM,Chiarini F,Lonetti A,Buontempo F,Orsini E,Pession A,Manzoli L,Martelli AM,Evangelisti C

更新日期：2018-03-01 00:00:00

abstract：:Scientists of numerous medical and life science disciplines met in Siena, Italy to discuss the latest proceedings in basic and clinical research. General models of interconnected linear and back-feeding cell-cycle control pathways provide a basis for applied molecular research. Cell-cycle determining factors essential...

journal_title：Journal of cellular physiology

authors： Stiegler P,Giordano A

更新日期：2000-12-01 00:00:00

abstract：:The aim of this study was to identify the molecules and pathways involved in the cross-talk between meniscus and synovium that may play a critical role in osteoarthritis (OA) pathophysiology. Samples of synovium and meniscus were collected from patients with early and end-stage OA and cultured alone or cocultured. Cyt...

journal_title：Journal of cellular physiology

authors： Favero M,Belluzzi E,Trisolino G,Goldring MB,Goldring SR,Cigolotti A,Pozzuoli A,Ruggieri P,Ramonda R,Grigolo B,Punzi L,Olivotto E

更新日期：2019-07-01 00:00:00

abstract：:Confluent cultures of adult bovine aortic endothelial (ABAE), corneal endothelial (BCE), and fetal bovine heart endothelial (FBHE) cells form a monolayer of highly flattened, closely apposed, and nonoverlapping cells. In ABAE and BCE cultures, this is associated with a 50-fold decrease in the rate of DNA sythesis and ...

journal_title：Journal of cellular physiology

authors： Savion N,Vlodavsky I,Greenburg G,Gospodarowicz D

更新日期：1982-02-01 00:00:00

abstract：:Cervical cancer is a deadly gynecological malignancy in need of innovative treatment strategies. Emerging preclinical data has suggested the benefits of nanocarriers over the traditional chemotherapy for cancer treatment. In particular, gold nanoparticles are gaining popularity due to gold's inert nature, limited side...

journal_title：Journal of cellular physiology

authors： Guan YH,Tian M,Liu XY,Wang YN

更新日期：2019-02-20 00:00:00

abstract：:Circular RNA TCF25 (circTCF25) has been proven to be upregulated in human malignancy and correlated with tumor process. Our study aimed to unravel whether circTCF25 dictates cellular activities of osteosarcoma cells and address the possible mechanisms associated with microRNA (miR). circTCF25 and miR-206 in clinical s...

journal_title：Journal of cellular physiology

authors： Wang Y,Shi S,Zhang Q,Dong H,Zhang J

更新日期：2020-02-13 00:00:00

abstract：:A decline in cell surface gamma-glutamyl transpeptidase specific activity was previously observed to be concomitant with C6 glial cell proliferation. To elucidate the underlying factor(s) mediating gamma-glutamyl transpeptidase down-regulation, the effects of C6 cell density and culture conditions on cell surface tran...

journal_title：Journal of cellular physiology

authors： Morgenstern K,Hanson-Painton O,Wang BL,De Bault L

更新日期：1992-01-01 00:00:00

abstract：:Prostate cancer (PCa) is one of the most common cancers and the fifth most common reason for cancer deaths in the males. Surgical castration combined with androgen deprivation therapy, antiandrogens, and androgen synthesis inhibitors is the current therapeutic modalities for PCa. These strategies inhibit androgen synt...

journal_title：Journal of cellular physiology

authors： Rezaei S,Mahjoubin Tehran M,Sahebkar A,Jalili A,Aghaee-Bakhtiari SH

更新日期：2020-04-01 00:00:00

abstract：:It was shown previously that mouse bone marrow cells transformed by simian virus 40 (SV40) show a reversible cell density-dependent phenotypic transition between the nonmacrophage (rapidly growing) and the macrophage (stationary) states; cells in low-density cultures are in the growing phase, express SV40 T antigen st...

journal_title：Journal of cellular physiology

authors： Tanigawa T,Takayama H,Takagi A,Kimura G

更新日期：1983-09-01 00:00:00

abstract：:The level of 1,25(OH)2D3 receptors in cultured mouse osteoblast-like (OB) cells is modulated by the rate of cell proliferation. We have studied two 1,25(OH)2D3-induced bioresponses to ascertain whether the changes in receptor levels during growth in culture alter cell responsiveness. Nuclear receptor levels were high ...

journal_title：Journal of cellular physiology

authors： Chen TL,Li JM,Ye TV,Cone CM,Feldman D

更新日期：1986-01-01 00:00:00

abstract：:Bethanechol, a muscarinic agonist, inhibits the initial rate of amiloride-sensitive Na uptake by intact mucosa of avian small intestine as well as by isolated chicken villus enterocytes, an effect that is maximal at 90 seconds and reverses by 6 minutes. Bethanechol similarly decreases intracellular pH in isolated cell...

journal_title：Journal of cellular physiology

authors： Musch MW,Drabik-Arvans D,Rao MC,Chang EB

更新日期：1992-08-01 00:00:00

abstract：:Although the role of several protooncogenes, including sis, myc, and myb in the regulation of growth and differentiation of vascular cells has been examined in some detail, limited information is available on the contribution of ras genes to these processes. In the present studies the influence of oncogenic ras transf...

journal_title：Journal of cellular physiology

authors： Sadhu DN,Lundberg MS,Burghardt RC,Ramos KS

更新日期：1994-12-01 00:00:00

abstract：:Cultured preadipose 3T3 cells are able to undergo a process of differentiation through which they are converted into adipose cells. Growth hormone induces this conversion in resting cultures but not in growing cultures. It was of interest to determine the period of cell sensitivity to the hormone and the timing of the...

journal_title：Journal of cellular physiology

authors： Morikawa M

更新日期：1986-08-01 00:00:00

abstract：:Many critical factors such as hypoxia, nutrient deficiency, activation of glycolytic pathway/Warburg effect contribute to the observed low pH in tumors compared to normal tissue. Studies suggest that such tumor specific acidic environment can be exploited for the development of therapeutic strategies against cancer. I...

journal_title：Journal of cellular physiology

authors： Shamim U,Hanif S,Albanyan A,Beck FW,Bao B,Wang Z,Banerjee S,Sarkar FH,Mohammad RM,Hadi SM,Azmi AS

更新日期：2012-04-01 00:00:00

abstract：:Carbonic anhydrase (CAH) was localized in the mitochondria-rich cells (MRC) of 1-week-old salamander larvae gill epithelium, in both MRC and pavement cells of 6-week-old larvae, and in regenerated stems of previously amputated gills. CAH activity of the MRC was measured quantitatively using a microscope densitometric ...

journal_title：Journal of cellular physiology

authors： Lewinson D,Rosenberg M,Goldenberg S,Warburg MR

更新日期：1987-01-01 00:00:00

abstract：:A rat pheochromocytoma cell line (PC12 cells) was used as a model to investigate the role of calmodulin and its multiple mRNAs in NGF-induced neuronal differentiation. The effect of NGF on the degree of differentiation was assayed using a simple differentiation scoring system. Significant increases in the differentiat...

journal_title：Journal of cellular physiology

authors： Bai G,Weiss B

更新日期：1991-12-01 00:00:00

abstract：:Cell division, neurite formation and acetylcholinesterase activity were examined in a clone (NBA2) of mouse neuroblastoma cells maintained for up to 120 hours in medium with pH values between 6.6 and 8.0. Growth rate decreased as pH was reduced from 7.8 to 6.6. Generation time at pH 7.4 was 25 hours, while the rate of...

journal_title：Journal of cellular physiology

authors： Bear MP,Schneider FH

更新日期：1977-04-01 00:00:00

abstract：:Previously we showed a rapid and transient inhibition of gap junctional communication (GJC) by platelet-derived growth factor (PDGF) in T51B rat liver epithelial cells expressing wild-type platelet-derived growth factor beta receptors (PDGFrbeta). This action of PDGF correlated with the hyperphosphorylation of the gap...

journal_title：Journal of cellular physiology

authors： Hossain MZ,Ao P,Boynton AL

更新日期：1998-08-01 00:00:00

abstract：:The extracellular matrix (ECM) is a dynamic component of tissue architecture that physically supports cells and actively influences their behavior. In the context of bone regeneration, cell-secreted ECMs have become of interest as they reproduce tissue-architecture and modulate the promising properties of mesenchymal ...

journal_title：Journal of cellular physiology

authors： Baroncelli M,van der Eerden BC,Kan YY,Alves RD,Demmers JA,van de Peppel J,van Leeuwen JP

更新日期：2018-01-01 00:00:00