The increase of calmodulin in PC12 cells induced by NGF is caused by differential expression of multiple mRNAs for calmodulin.

abstract：:Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), are incurable diseases characterized by progressive loss of cognitive or motor function, which construct a serious threat to the life quality of aging populations and their life spans. Apelin is an ...

journal_title：Journal of cellular physiology

authors： Luo H,Han L,Xu J

更新日期：2020-02-01 00:00:00

abstract：:We previously revealed that epithelial-to-mesenchymal transition (EMT) was mediated by ΔNp63β, a splicing variant of ΔNp63, in oral squamous cell carcinoma (OSCC). Recent studies have highlighted the involvement of microRNA (miRNA) in EMT of cancer cells, though the mechanism remains unclear. To identify miRNAs respon...

journal_title：Journal of cellular physiology

authors： Hashiguchi Y,Kawano S,Goto Y,Yasuda K,Kaneko N,Sakamoto T,Matsubara R,Jinno T,Maruse Y,Tanaka H,Morioka M,Hattori T,Tanaka S,Kiyoshima T,Nakamura S

更新日期：2018-10-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:We have previously shown that retinoic acid (RA) has protective effects on high glucose (HG)-induced cardiomyocyte apoptosis. To further elucidate the molecular mechanisms of RA effects, we determined the interaction between nuclear factor (NF)-κB and RA signaling. HG induced a sustained phosphorylation of IKK/IκBα an...

journal_title：Journal of cellular physiology

authors： Nizamutdinova IT,Guleria RS,Singh AB,Kendall JA Jr,Baker KM,Pan J

更新日期：2013-02-01 00:00:00

abstract：:The manipulation of autophagy provides a new opportunity for highly effective anticancer therapies. Recently, we showed that photodynamic therapy (PDT) with nitrogen-doped titanium dioxide (N-TiO2 ) nanoparticles (NPs) could promote the reactive oxygen species (ROS)-dependent autophagy in leukemia cells. However, the ...

journal_title：Journal of cellular physiology

authors： Mohammadalipour Z,Rahmati M,Khataee A,Moosavi MA

更新日期：2020-11-01 00:00:00

abstract：:Hyaluronate degradation was examined in cultures of vascular wall cells (bovine aortic endothelial cells, rat aortic smooth muscle cells) and in nonvascular cells (chick embryo fibroblasts). The three cell types examined all produced hyaluronidase activity in culture which had a strict acidic pH requirement for activi...

journal_title：Journal of cellular physiology

authors： McGuire PG,Castellot JJ Jr,Orkin RW

更新日期：1987-11-01 00:00:00

abstract：:The basic fibroblast growth factor (FGF) is a potent mitogen that has vascular endothelium as one of its principle target cells. Recent work has provided both the complete amino acid sequence of basic FGF and the nucleotide sequence of the genes for both human and bovine basic FGF. Although capillary endothelial cells...

journal_title：Journal of cellular physiology

authors： Hanneken A,Lutty GA,McLeod DS,Robey F,Harvey AK,Hjelmeland LM

更新日期：1989-01-01 00:00:00

abstract：:The cardiac glyoside, ouabain, normally kills HeLa cells at concentrations of about 10-7 M or greater. By treating a population of HeLa cells with increasingly higher concentrations of the drug, a vaiant population was obtained of HeLa cells capable of growing in medium containing 10-4 M ouabain. Inhibition of volume ...

journal_title：Journal of cellular physiology

authors： Rosenberg HM

更新日期：1975-02-01 00:00:00

abstract：:Cell-based cartilage resurfacing requires ex vivo expansion of autologous articular chondrocytes. Defined culture conditions minimize expansion-dependent phenotypic alterations but maintenance of the cells' differentiation potential must be carefully assessed. Transforming growth factor β-1 (TGF β-1) positively regula...

journal_title：Journal of cellular physiology

authors： Narcisi R,Quarto R,Ulivi V,Muraglia A,Molfetta L,Giannoni P

更新日期：2012-09-01 00:00:00

abstract：:Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2. Muc4/SMC can act as an intramembrane ligand for ErbB2 via an EGF-like ...

journal_title：Journal of cellular physiology

authors： Price-Schiavi SA,Andrechek E,Idris N,Li P,Rong M,Zhang J,Carothers Carraway CA,Muller WJ,Carraway KL

更新日期：2005-04-01 00:00:00

abstract：:Methylglyoxal bis-(guanylhydrazone) (mGBG) blocked the stimulation of DNA synthesis in quiescent, density-inhibited BALB/c-3T3 cells treated with platelet-derived growth factor (PDGF) and platelet-poor plasma (PPP). Competence formation produced by a transient exposure to PDGF was not effected by mGBG. In contrast, mG...

journal_title：Journal of cellular physiology

authors： Wharton W,Van Wyk JJ,Pledger WJ

更新日期：1981-04-01 00:00:00

abstract：:We report the continuous growth maintenance of untransformed and chemically transformed fibroblasts (AKR-2B, AKR-MCA cells) in low concentrations of serum (0.1% FBS). The cell lines established (AKR-0.1F, MCA-0.1F) proliferated at rates comparable to cells maintained under high serum conditions (10% FBS). Complete rem...

journal_title：Journal of cellular physiology

authors： Mulder KM,Brattain MG

更新日期：1989-03-01 00:00:00

abstract：:B cell activating factor from the TNF family (BAFF) stimulates B-cell proliferation and survival, but excessive BAFF promotes the development of aggressive B cells leading to malignant and autoimmune diseases. Recently, we have reported that rapamycin, a macrocyclic lactone, attenuates human soluble BAFF (hsBAFF)-stim...

journal_title：Journal of cellular physiology

authors： Zeng Q,Qin S,Zhang H,Liu B,Qin J,Wang X,Zhang R,Liu C,Dong X,Zhang S,Huang S,Chen L

更新日期：2018-01-01 00:00:00

abstract：:Multiple modalities for lung cancer therapy have emerged in the past decade, whereas their clinical applications and survival-beneficiary is little known. Vaccination with dendritic cells (DCs) or DCs/cytokine-induced killer (CIK) cells has shown limited success in the treatment of patients with advanced non-small-cel...

journal_title：Journal of cellular physiology

authors： Mohsenzadegan M,Peng RW,Roudi R

更新日期：2020-01-01 00:00:00

abstract：:We performed a network meta-analysis (NMA) to compare the short- and long-term efficacy of Gemcitabine, Gemcitabine + S-1 (tegafur), Gemcitabine + nab-paclitaxel, Gemcitabine + Capecitabine, Gemcitabine + Cisplatin, FOLFIRINOX (oxaliplatin + irinotecan + fluorouracil + leucovorin), Gemcitabine + oxaliplatin, Gemcitabi...

journal_title：Journal of cellular physiology

authors： Zhang SH,Liu GF,Li XF,Liu L,Yu SN

更新日期：2018-04-01 00:00:00

abstract：:Although it is well established that epidermal growth factor receptors (EGFRs) are asymmetrically expressed at the basolateral plasma membrane in polarized epithelial cells, how this process is regulated is not known. The purpose of this study was to address the mechanism of directed EGFR basolateral sorting using the...

journal_title：Journal of cellular physiology

authors： Hobert M,Carlin C

更新日期：1995-03-01 00:00:00

abstract：:B16 mouse melanoma cells are grown inhibited by cyclic AMP or by retinoic acid (RA). However, the combination of these two agents results in less growth inhibition than either agent alone. In order to investigate this interaction, cells were selected for resistance to 8-bromo-cyclic AMP-induced growth inhibition. Two ...

journal_title：Journal of cellular physiology

authors： Niles RM,Loewy B

更新日期：1991-04-01 00:00:00

abstract：:We studied the clinicopathological significance for Calreticulin (CRT) expression in pancreatic cancer (PC), and its functional relationship with other signaling genes (especially with p53) in regulating the biological behavior of PC cells. IHC, IF, IB, and real-time PCR were used to detect CRT expression in PC, while...

journal_title：Journal of cellular physiology

authors： Sheng W,Chen C,Dong M,Zhou J,Liu Q,Dong Q,Li F

更新日期：2014-07-01 00:00:00

abstract：:MicroRNAs (miRNAs or miRs) are small noncoding RNAs that play critical roles in muscle cell proliferation and differentiation via post-transcriptional regulation of gene expression. Here, based on our previous high-throughput sequencing results, we evaluated miRNA-499 (miR-499) functions during myoblast proliferation ...

journal_title：Journal of cellular physiology

authors： Wu J,Yue B,Lan X,Wang Y,Fang X,Ma Y,Bai Y,Qi X,Zhang C,Chen H

更新日期：2019-03-01 00:00:00

abstract：:Pathological calcification represents an event that consequently leads to a distinct elevation in the morbidity and mortality of patients with chronic kidney disease (CKD) in addition to strengthening its correlation with hyperphosphatemia. Epigenomic regulation by specific microRNAs (miRNAs) is reported to be involve...

journal_title：Journal of cellular physiology

authors： Xu TH,Qiu XB,Sheng ZT,Han YR,Wang J,Tian BY,Yao L

更新日期：2019-08-01 00:00:00

abstract：:Cation-Cl- cotransporters (CCCs) belong to a large family of proteins that includes 9 isoforms, two of which have still not been ascribed a transport function (CCC8 and CCC9) while the others are all known to promote Cl(-)-coupled Na+ and/or K+ movement at the cell surface. The CCCs are also included in a larger famil...

journal_title：Journal of cellular physiology

authors： Daigle ND,Carpentier GA,Frenette-Cotton R,Simard MG,Lefoll MH,Noël M,Caron L,Noël J,Isenring P

更新日期：2009-09-01 00:00:00

abstract：:Interleukin-34 (IL-34) shares a common receptor with macrophage colony-stimulating factor (M-CSF), and can bind to CSF-1R, induces lymphocytes differentiation, proliferation, and regulates the synthesis of inflammatory components. Recent findings reported aberrant expression of IL-34 in several autoimmune disorders, s...

journal_title：Journal of cellular physiology

authors： Xu WD,Huang AF,Fu L,Liu XY,Su LC

更新日期：2019-12-01 00:00:00

abstract：:Proprotein convertase subtilisin/kexin 4 (PCSK4) is implicated for sperm fertilizing ability, based on studies using Pcsk4-null mice. Herein we demonstrated proprotein convertase (PC) activity in intact sperm and acrosomal vesicles. To determine whether this activity was important for sperm fertilizing ability, a pept...

journal_title：Journal of cellular physiology

authors： Iamsaard S,Vanichviriyakit R,Hommalai G,Saewu A,Srakaew N,Withyachumnarnkul B,Basak A,Tanphaichitr N

更新日期：2011-11-01 00:00:00

abstract：:Chrysophanol is an anthraquinone compound, mainly isolated from rhubarb, with anti-cancer effects on some types of cancer cells. However, effects of chrysophanol on human choriocarcinoma cells are not known. Therefore, the objective of this study was to determine effects of chrysophanol on choriocarcinoma cells (JAR a...

journal_title：Journal of cellular physiology

authors： Lim W,Yang C,Bazer FW,Song G

更新日期：2017-02-01 00:00:00

abstract：:Tight junctions govern the paracellular permeability of endothelial and epithelial cells. Aberrations of tight junction function are an early and key event during the vascular spread of cancer and inflammation. This study sought to determine the role of estrogen in the regulation of tight junctions and expression of m...

journal_title：Journal of cellular physiology

authors： Ye L,Martin TA,Parr C,Harrison GM,Mansel RE,Jiang WG

更新日期：2003-08-01 00:00:00

abstract：:The level of adhesion molecules expressed at the endothelial cell surface is critical in the control of inflammation. Adenylate cyclase (AC) activity allowing cyclic adenosine monophosphate (cAMP) production can modulate the inflammatory process. We investigated the AC-dependent modulation of ICAM-1 surface expression...

journal_title：Journal of cellular physiology

authors： Bernot D,Peiretti F,Canault M,Juhan-Vague I,Nalbone G

更新日期：2005-02-01 00:00:00

abstract：:Photoperiod regulates the seasonal reproductive rhythms of mammals by influencing the development and function of sexual organs; however, the underlying mechanism remains unclear. We examined the morphology and functioning of the main sex organs of striped dwarf hamsters (Cricetulus barabensis) under different photope...

journal_title：Journal of cellular physiology

authors： Mou J,Xu J,Wang Z,Wang C,Yang X,Wang X,Xue H,Wu M,Xu L

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:MiR-152 has been reported as a tumor suppressor microRNA that is downregulated in a number of cancers, including colorectal cancer (CRC). A recent study suggested that miR-152 could be one of the key regulators of CRC. The aim of this study is to investigate the role of miR-152 in CRC and its mechanisms. ME...

journal_title：Journal of cellular physiology

authors： Ghazanchaei A,Mansoori B,Mohammadi A,Biglari A,Baradaran B

更新日期：2018-01-01 00:00:00

abstract：:Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The binding to the two site...

journal_title：Journal of cellular physiology

authors： Moscatelli D

更新日期：1987-04-01 00:00:00

abstract：:Recent studies have suggested that interferons (IFNs) have an antifibrotic effect in the liver independent of their antiviral effect although its detailed mechanism remains largely unknown. Some microRNAs have been reported to regulate pathophysiological activities of hepatic stellate cells (HSCs). We performed analys...

journal_title：Journal of cellular physiology

authors： Sekiya Y,Ogawa T,Iizuka M,Yoshizato K,Ikeda K,Kawada N

更新日期：2011-10-01 00:00:00