Wnt5a Induces Collagen Production by Human Periodontal Ligament Cells Through TGFβ1-Mediated Upregulation of Periostin Expression.

abstract：:NIH-3T3 cells transformed by the EJ-ras oncogene display reduced platelet-derived growth factor (PDGF)-stimulated phospholipase C activity as measured by inositol 1,4,5-triphosphate (IP3) synthesis and Ca2+ mobilization. The lack of PDGF-stimulated Ca2+ mobilization in EJ-ras transformed cells is not due to a loss of ...

journal_title：Journal of cellular physiology

authors： Olinger PL,Benjamin CW,Gorman RR,Connor JA

更新日期：1989-05-01 00:00:00

abstract：:C6 glioma cells possess beta adrenergic receptors coupled with adenylate cyclase which can be irreversibly blocked by bromoacetylaminomethylpindolol (Br-AAM-pindolol), a beta adrenergic antagonist. With 1 microM Br-AAM-pindolol, more than 80% of beta adrenergic receptors, labeled by (3H)-dihydroalprenolol [3H)-DHA), w...

journal_title：Journal of cellular physiology

authors： Homburger V,Pantaloni C,Lucas M,Gozlan H,Bockaert J

更新日期：1984-12-01 00:00:00

abstract：:The serine protease thrombin has been proposed to be involved in neuromuscular plasticity. Its specific receptor "protease activated receptor-1" (PAR-1), a G protein-coupled receptor, has been shown to be expressed in myoblasts but not after fusion (Suidan et al., 1996 J Biol Chem 271:29162-29169). In the present work...

journal_title：Journal of cellular physiology

authors： Chevessier F,Hantaï D,Verdière-Sahuqué M

更新日期：2001-11-01 00:00:00

abstract：:This study examines the regulation of Swarm rat chondrosarcoma (SRC) cell proliferation in vitro. In serum-free cultures, SRC cells showed only transient DNA synthesis and this was increased by serum. Transforming growth factor-beta (TGF-beta) was identified as an essential serum component, since the mitogenic effect ...

journal_title：Journal of cellular physiology

authors： Guerne PA,Lotz M

更新日期：1991-10-01 00:00:00

abstract：:We investigated gene expression profiles of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in differentiated and non-differentiated retinal pigment epithelial (RPE) cells during oxidative stress. Human RPE cells were grown in culture on laminin-coated flasks to obtain differenti...

journal_title：Journal of cellular physiology

authors： Ohno-Matsui K,Morita I,Tombran-Tink J,Mrazek D,Onodera M,Uetama T,Hayano M,Murota SI,Mochizuki M

更新日期：2001-12-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) have been found to be tightly correlated with the progression of prostate cancer (PC). In this study, we investigated the effects of an SDF-1α/CXCR4 inhibitor, AMD3100, on cell progression and metastasis potential of human PC cells. Human PC ce...

journal_title：Journal of cellular physiology

authors： Zhu WB,Zhao ZF,Zhou X

更新日期：2019-07-01 00:00:00

abstract：:An unusual inward current which is slowly elicited in the Xenopus oocyte membrane during sustained depolarization is reportedly carried by Na+. It is thought that Na+ selective channels are in some way induced to become voltage-sensitive by the depolarization. Earlier studies report that the induction process involves...

journal_title：Journal of cellular physiology

authors： Charpentier G,Kado RT

更新日期：1999-02-01 00:00:00

abstract：:Necrotizing Enterocolitis (NEC) is a severe inflammatory disorder leading to high morbidity and mortality rates. A growing body of evidence demonstrate the key role of the Toll like receptor 4 (TLR4) in NEC. This membranal receptor recognizes lipopolysaccharides (LPS) from the bacterial wall and triggers an inflammato...

journal_title：Journal of cellular physiology

authors： Bein A,Zilbershtein A,Golosovsky M,Davidov D,Schwartz B

更新日期：2017-02-01 00:00:00

abstract：:We determined the mitogenic and comitogenic properties of tumor promoters in the indole alkaloid series; agents that differ structurally from 12-0-tetradecanoylphorbol-13-acetate (TPA), which is known to be a lymphocyte mitogen. Teleocidin and dihydroteleocidin B were mitogenic for human lymphocytes, and lyngbyatoxin ...

journal_title：Journal of cellular physiology

authors： Novogrodsky A,Patya M,Fujiki H,Rubin AL,Stenzel KH

更新日期：1984-07-01 00:00:00

abstract：:Apoptosis is also known as programmed cell death. Apoptosis plays an essential role in maintaining normal tissue and cell physiology in multicellular organisms. Clearance of aberrant or pre-cancerous cells occurs through the induction of apoptosis. It has been reported that many tumors and tumor cell lines have dysfun...

journal_title：Journal of cellular physiology

authors： Holmes WF,Soprano DR,Soprano KJ

更新日期：2004-06-01 00:00:00

abstract：:The aim of the present work was to examine the role of muscarinic acetylcholine receptors (mAChRs) on apoptosis in human skin fibroblast cells. Neonatal human skin fibroblast cultures were stimulated with pilocarpine in the presence or absence of specific antagonists. Pilocarpine stimulates apoptosis, total inositol p...

journal_title：Journal of cellular physiology

authors： Reina S,Sterin-Borda L,Passafaro D,Borda E

更新日期：2010-03-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) hyperplasia plays a central role in chronic and acute vascular pathology including arteriosclerosis and restenosis following vascular surgery. The glycosaminoglycans of the heparan sulfate class, including heparin, inhibit VSMC proliferation in animals and in culture. Heparin binds t...

journal_title：Journal of cellular physiology

authors： Delmolino LM,Castellot JJ Jr

更新日期：1997-12-01 00:00:00

abstract：:Dental follicle cells (DFCs) activate and recruit osteoclasts for tooth development and tooth eruption, whereas DFCs themselves differentiate into osteoblasts to form alveolar bone surrounding tooth roots through the interaction with Hertwig's epithelial root sheath (HERS). Also during tooth development, parathyroid h...

journal_title：Journal of cellular physiology

authors： Zhang J,Liao L,Li Y,Xu Y,Guo W,Tian W,Zou S

更新日期：2019-07-01 00:00:00

abstract：:Exposure to D-allose has been demonstrated to lead to decreased 2-deoxy-D-glucose (2-DG) and 3-0-methyl-D-glucose transport in the V79 Chinese hamster lung fibroblast cell line. The effect of D-allose 1) was maximal after 4 hours exposure to the cells; 2) was optimal between 2.77 and 5.55 mM D-allose; and 3) led to a ...

journal_title：Journal of cellular physiology

authors： Germinario RJ,Kristof A,Chang Z,Manuel S

更新日期：1990-11-01 00:00:00

abstract：:Gene therapy using biocompatible cationic liposomes is amongst promising approaches that decreases death from cancers. Here an invasive multidrug resistant cell model has been developed by lentiviral transfection. In parallel phospholipids have been covalently conjugated to TAT, MMP2, and Herceptin. The functional lip...

journal_title：Journal of cellular physiology

authors： Gholamian Dehkordi N,Elahian F,Khosravian P,Mirzaei SA

更新日期：2019-11-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:The presence of an appropriate number of viable cells is prerequisite for successive differentiation during chondrogenesis. Chondrogenic differentiation has been reported to be influenced by mechanical stimuli. This research aimed to study the effects of cyclic compressive stress on cell viability of rat bone marrow-d...

journal_title：Journal of cellular physiology

authors： Wang Y,Wang J,Bai D,Song J,Ye R,Zhao Z,Lei L,Hao J,Jiang C,Fang S,An S,Cheng Q,Li J

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Surgical stress has been suggested to facilitate colon cancer growth and metastasis. However, the precise mechanisms by which surgical trauma promotes colon cancer progression remain poorly understood. METHODS:To unravel the mechanisms underlying surgery-induced colon cancer progression, a syngenic transpla...

journal_title：Journal of cellular physiology

authors： Sun Z,Du C,Xu P,Miao C

更新日期：2019-04-01 00:00:00

abstract：:Alkaptonuria (AKU) is a rare genetic disease that affects the entire joint. Current standard of treatment is palliative and little is known about AKU physiopathology. Chondroptosis, a peculiar type of cell death in cartilage, has been so far reported to occur in osteoarthritis, a rheumatic disease that shares some fea...

journal_title：Journal of cellular physiology

authors： Millucci L,Giorgetti G,Viti C,Ghezzi L,Gambassi S,Braconi D,Marzocchi B,Paffetti A,Lupetti P,Bernardini G,Orlandini M,Santucci A

更新日期：2015-05-01 00:00:00

abstract：:The effects of adenosine and two analogs, L-phenylisopropyladenosine (L-PIA) and 5'-N-ethylcarboxamidoadenosine (NECA), on cAMP production and on platelet-derived growth factor (PDGF)-stimulated initiation of DNA synthesis in growth-arrested cultures of rat arterial smooth muscle cells (SMC) were studied. The intracel...

journal_title：Journal of cellular physiology

authors： Jonzon B,Nilsson J,Fredholm BB

更新日期：1985-09-01 00:00:00

abstract：:Respiratory tract epithelia are one type of tissue targeted by vitamin A. In this study the effects of vitamin A and its analogs (retinoids) on human bronchial epithelial (HBE) cells have been investigated in a serum-free hormone-supplemented medium. This serum-free medium, which was developed for the long-term cultiv...

journal_title：Journal of cellular physiology

authors： Wu R,Wu MM

更新日期：1986-04-01 00:00:00

abstract：:Calreticulin is an ER calcium-storage protein, which influences gene expression and cell adhesion. In this study, we analysed the differences in adhesive properties of calreticulin under- and overexpressing fibroblasts in relation to the calmodulin- and calcium/calmodulin-dependent kinase II (CaMK II)-dependent signal...

journal_title：Journal of cellular physiology

authors： Szabo E,Papp S,Opas M

更新日期：2007-10-01 00:00:00

abstract：:We compared the effects of endothelial-synthesized matrix and purified matrix molecules on pericyte (PC) and aortic smooth muscle cell (SMC) growth, heparin sensitivity, and contractile phenotype in vitro. When PC are plated on endothelial-synthesized (EC) matrix, cell number is, on average, 3.1-fold higher than ident...

journal_title：Journal of cellular physiology

authors： Newcomb PM,Herman IM

更新日期：1993-05-01 00:00:00

abstract：:Pin1 is a peptidyl prolyl cis-trans isomerase that specifically binds to the phosphoserine-proline or phosphothreonine-proline motifs of numerous proteins. Previously, we reported that Pin1 deficiency resulted in defects in osteoblast differentiation during early bone development. In this study, we found that adult Pi...

journal_title：Journal of cellular physiology

authors： Yoon WJ,Islam R,Cho YD,Ryu KM,Shin HR,Woo KM,Baek JH,Ryoo HM

更新日期：2015-03-01 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) is characterized by the formation of neurofibromas, benign tumors of the peripheral nerve consisting essentially of Schwann cells, which can sometimes turn malignant to form neurofibrosarcomas. The mechanism of progression toward a malignant phenotype remains largely unknown. In this rep...

journal_title：Journal of cellular physiology

authors： Badache A,De Vries GH

更新日期：1998-11-01 00:00:00

abstract：:Reduced sperm motility (asthenospermia) and resulting infertility arise from deletion of the Plasma Membrane Ca2+ -ATPase 4 (Pmca4) gene which encodes the highly conserved Ca2+ efflux pump, PMCA4. This is the major Ca2+ clearance protein in murine sperm. Since the mechanism underlying asthenospermia in PMCA4's absence...

journal_title：Journal of cellular physiology

authors： Olli KE,Li K,Galileo DS,Martin-DeLeon PA

更新日期：2018-01-01 00:00:00

abstract：:Alkaptonuria (AKU) is a rare disease correlated with deficiency of the enzyme homogentisate 1,2 dioxygenase, which causes homogentisic acid (HGA) accumulation. HGA is subjected to oxidation/polymerization reactions, leading to the production of a peculiar melanin-like pigmentation (ochronosis) after chronic inflammati...

journal_title：Journal of cellular physiology

authors： Schiavone ML,Millucci L,Bernardini G,Giustarini D,Rossi R,Marzocchi B,Santucci A

更新日期：2020-10-01 00:00:00

abstract：:Adipose-derived stem cells (ADSCs) are a type of mesenchymal stem cells isolated from adipose tissue and have the ability to differentiate into adipogenic, osteogenic, and chondrogenic lineages. Despite their great therapeutic potentials, previous studies showed that ADSCs could enhance the proliferation and metastati...

journal_title：Journal of cellular physiology

authors： Chan YW,So C,Yau KL,Chiu KC,Wang X,Chan FL,Tsang SY

更新日期：2020-10-01 00:00:00

abstract：:Increased neovascularization is commonly observed in hemorrhagic plaques and associated with rupture of atherosclerotic lesions. This study aims to investigate whether hemin accumulated at the site of hematoma promotes neovascularization through affecting the growth and function of endothelial progenitor cells (EPCs) ...

journal_title：Journal of cellular physiology

authors： Wang JY,Lee YT,Chang PF,Chau LY

更新日期：2009-06-01 00:00:00

abstract：:Prostaglandin F2α (PGF2α) plays multiple roles on bone metabolism by regulating a wide range of signaling pathways. PGF2α, via activation of PKC, stimulates Na-dependent inorganic phosphate (Pi) transport system in osteoblasts; up-regulates interleukin (IL)-6 synthesis; increases vascular endothelial growth factor (VE...

journal_title：Journal of cellular physiology

authors： Agas D,Marchetti L,Hurley MM,Sabbieti MG

更新日期：2013-01-01 00:00:00