Parathyroid hormone-related peptide (1-34) promotes tooth eruption and inhibits osteogenesis of dental follicle cells during tooth development.

abstract：:Withangulatin A is a newly identified in vitro topoisomerase II inhibitor isolated from the Chinese antitumor herb Physalis angulata. In vivo, it was found to be cytotoxic, capable of suppressing general protein synthesis and of inducing the synthesis of a small set of proteins including those generated by heat-shock ...

journal_title：Journal of cellular physiology

authors： Lee WC,Lin KY,Chen CM,Chen ZT,Liu HJ,Lai YK

更新日期：1991-10-01 00:00:00

abstract：:A method for killing dividing cells (Puck and Kao, '67) was adapted for the elimination of dividing heart muscle cells (myoblasts) in cultures. We have used this method to demonstrate their presence and to estimate their number as well as the number of nondividing heart muscle cells (myocytes) in the neo-natal rat hea...

journal_title：Journal of cellular physiology

authors： Masse MJ,Harary I

更新日期：1980-11-01 00:00:00

abstract：:Atherothrombotic cardiovascular disease is a major cause of mortality throughout the world. Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have been traditionally used in the management of cardiovascular disease and can help in modifying its progression, particul...

journal_title：Journal of cellular physiology

authors： Keihanian F,Saeidinia A,Bagheri RK,Johnston TP,Sahebkar A

更新日期：2018-06-01 00:00:00

abstract：:Priapism, a prolonged penile erection in the absence of sexual arousal, is common among patients with sickle cell disease (SCD). Hypogonadism is also common in patients with SCD. While the administration of exogenous testosterone reverses hypogonadism, it is contraceptive. We hypothesized that the stimulation of endog...

journal_title：Journal of cellular physiology

authors： Musicki B,Karakus S,La Favor JD,Chen H,Silva FH,Sturny M,Zirkin BR,Burnett AL

更新日期：2020-09-24 00:00:00

abstract：:Spontaneously arising, TGF beta 1-resistant colonies were isolated directly from the soft agarose plates of MOSER human colon carcinoma cells grown in the presence of TGF beta 1 but in the absence of serum. The colonies were cloned by limiting dilution and screened in a monolayer proliferation assay for sensitivity to...

journal_title：Journal of cellular physiology

authors： Zhou GH,Sechrist GL,Brattain MG,Mulder KM

更新日期：1995-12-01 00:00:00

abstract：:We have examined the transport of amino acids by the sodium-dependent "A" and "ASC" system in thymic- and splenic-derived lymphocytes from the Long-Evans rat. Lymphocytes derived from the thymus transport amino acids by both the "A" and "ASC" systems, whereas lymphocytes from the spleen transport amino acids by the "A...

journal_title：Journal of cellular physiology

authors： Wise WC

更新日期：1978-11-01 00:00:00

abstract：:Pleiotropic human KB cell mutants, selected for resistance to a conjugate of epidermal growth factor with Pseudomonas exotoxin (PE-EGF), were characterized genetically. These mutants have a pleiotropic phenotype, which includes reduced number of EGF receptors and reduced growth rate. Hybrid cells between HeLa D98 and ...

journal_title：Journal of cellular physiology

authors： Amano F,Pastan I,Gottesman MM

更新日期：1988-06-01 00:00:00

abstract：:During the development of atherosclerotic and fibromuscular proliferates/lesions, smooth muscle cells (SMC) in the media, particularly near the lumen, are activated to migrate into the intima, where they continue to proliferate to form an intimal thickening. It is to date unclear whether SMCs situated adjacent to the ...

journal_title：Journal of cellular physiology

authors： Betz E,Fallier-Becker P,Wolburg-Buchholz K,Fotev Z

更新日期：1991-06-01 00:00:00

abstract：:We can distinguish two classes of membrane transport changes in cultured cells: (a) growth-rate contingent changes are those which occur in coordination with the onset of density-dependent inhibition of growth; (b) transformation-specific changes are those which occur when cells become transformed, and which can be de...

journal_title：Journal of cellular physiology

authors： Weber MJ,Hale AH,Yau TM,Buckman T,Johnson M,Brady TM,LaRossa DD

更新日期：1976-12-01 00:00:00

abstract：:Primary astroglial cultures were used to compare the relationships to cell cycling of dolichol-linked glycoprotein synthesis, and of availability of mevalonate, the precursor of dolichol and other isoprenoid lipids. With shift-up to 10% serum (time 0) after 48 h of serum depletion, the proportion of cells in S phase (...

journal_title：Journal of cellular physiology

authors： Langan TJ,Slater MC

更新日期：1991-11-01 00:00:00

abstract：:Sirtuin 3 (SIRT3) a mitochondrial enzyme that plays an important role in energy homeostasis, cardiac remodeling, and heart failure (HF). The expression of SIRT3 declines with advanced age, cardiovascular, and metabolic diseases. Accumulating evidence suggests that SIRT3 plays a critical role in protecting the heart fr...

journal_title：Journal of cellular physiology

authors： He X,Zeng H,Chen JX

更新日期：2019-03-01 00:00:00

abstract：:The level of poly A+ RNA in growing cultures of human diploid fibroblasts is 1.8-fold times greater than in resting cultures. The level of functional ribosomes in growing cultures is 2.8 times that in resting cultures. Since transit times are similar in both types of cells, it can be concluded that the rate of protein...

journal_title：Journal of cellular physiology

authors： Meedel TH,Levine EM

更新日期：1978-02-01 00:00:00

abstract：:Fibrosis is a common pathological condition associated with abnormal repair after tissue injury. However, the etiology and molecular mechanisms of fibrosis are still not well-understood. Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) belongs to the TNF superfamily and acts by binding to its recepto...

journal_title：Journal of cellular physiology

authors： Zhang Y,Zeng W,Xia Y

更新日期：2020-09-30 00:00:00

abstract：:In Xenopus oocytes injected with total rat pituitary GH3 cell RNA, thyrotropin-releasing hormone (TRH) causes the activation of the inositol lipid transduction pathway and the induction of chloride conductance via calcium-activated channels (Oron et al., 1987, Mol. Endocrinol., 1:918-925). This response exhibits chara...

journal_title：Journal of cellular physiology

authors： Lipinsky D,Gershengorn MC,Oron Y

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have a severe vitamin D deficiency and increasing epidemiological data suggesting that this deficiency may play a role in overall morbidity and mortality associated with CKD. It is known that vitamin D regulates the immune system, however, in dialysis patients this ...

journal_title：Journal of cellular physiology

authors： Almeida ACSF,Siqueira MC,Bonan NB,Dambiski A,Bertuzzo G,Moreno-Amaral AN,Barreto FC

更新日期：2019-02-25 00:00:00

abstract：:We investigated the regulation of Cl- secretion by adrenoceptors in polarized 16HBE14o- human bronchial epithelial cells. Treatment with the nonselective β adrenoceptor agonist isoprenaline stimulated an increase in short-circuit current (ISC ), which was inhibited by the β adrenoceptor blocker propranolol. Treatment ...

journal_title：Journal of cellular physiology

authors： Zhang RG,Yip CY,Pan KW,Cai MY,Ko WH

更新日期：2020-11-01 00:00:00

abstract：:Bradykinin (BK) is a potent short-lived effector belonging to a class of peptides known as kinins. It participates in inflammatory and vascular regulation and processes including angioedema, tissue permeability, vascular dilation, and smooth muscle contraction. BK exerts its biological effects through the activation o...

journal_title：Journal of cellular physiology

authors： Prado GN,Taylor L,Zhou X,Ricupero D,Mierke DF,Polgar P

更新日期：2002-12-01 00:00:00

abstract：:The trigger for bone remodeling is bone resorption by osteoclasts. Osteoclast differentiation only occurs on the old bone, which needs to be repaired under physiological conditions. However, uncontrolled bone resorption is often observed in pro-inflammatory bone diseases, such as rheumatoid arthritis. Mature osteoclas...

journal_title：Journal of cellular physiology

authors： Matsuura T,Ichinose S,Akiyama M,Kasahara Y,Tachikawa N,Nakahama KI

更新日期：2017-07-01 00:00:00

abstract：:Catecholamines produce mitotic inhibition in primary cell cultures of human keratinocytes probably via a block in the G2 part of the cell cycle. Epinephrine produced significant mitotic inhibition (49%) at a concentration as low as 4.5 X 10(-10) M, while its analog, isoproterenol, produced 47% inhibition at 1 X 10(-10...

journal_title：Journal of cellular physiology

authors： Harper RA,Flaxman BA

更新日期：1975-10-01 00:00:00

abstract：:In vitro incubation of hepatocytes acutely isolated from adult male rats leads to a rapid conversion of the adrenergic activation of glycogenolysis from an alpha 1-receptor (alpha 1AR) to a beta 2-receptor (beta 2AR) mediated response within 4 h. In order to understand the underlying mechanism, we examined time-depend...

journal_title：Journal of cellular physiology

authors： Ishac EJ,Lazar-Wesley E,Kunos G

更新日期：1992-07-01 00:00:00

abstract：:High potassium concentrations altered the morphology and the ability to grow in soft agar in 6m2 cells, a clone of rat kidney cells infected with a temperature-sensitive mutant of Moloney sarcoma virus. Approximately 60% of cells exhibited normal morphology in the presence of 94.8 mM potassium in isotonic medium at th...

journal_title：Journal of cellular physiology

authors： Lai CN,Becker FF

更新日期：1985-11-01 00:00:00

abstract：:Recently, ATP has gained much interest as an extracellular messenger involved in the communication of calcium signals between cells. The mechanism of ATP release is, however, still a matter of debate. In the present study we investigated the possible contribution of connexin hemichannels or ion channels in the release...

journal_title：Journal of cellular physiology

authors： Braet K,Aspeslagh S,Vandamme W,Willecke K,Martin PE,Evans WH,Leybaert L

更新日期：2003-11-01 00:00:00

abstract：:Vitamin D3 metabolites regulate the differentiation of chondrocytes isolated from the growth zone or resting zone of rat costochondral cartilage. Since some of the direct membrane effects of vitamin D metabolites are nongenomic, we hypothesized that protein kinase C (PKC) plays a role in signal transduction for these ...

journal_title：Journal of cellular physiology

authors： Sylvia VL,Schwartz Z,Schuman L,Morgan RT,Mackey S,Gomez R,Boyan BD

更新日期：1993-11-01 00:00:00

abstract：:An in-depth understanding of circular RNAs (circRNAs) indicates that they are abundant in the eukaryotic transcriptome. Many circRNAs act as microRNA sponges; thus, they represent a new type of regulatory factor. However, the role of circRNA in colorectal cancer (CRC) remains largely unknown. Low circ_0021977 expressi...

journal_title：Journal of cellular physiology

authors： Lu C,Jiang W,Hui B,Rong D,Fu K,Dong C,Tang W,Cao H

更新日期：2020-03-01 00:00:00

abstract：:The activation of the Wnt/β-catenin signaling pathway is critical for skeletal development but surprisingly little is known about the requirements for the specific frizzled (Fzd) receptors that recognize Wnt ligands. To define the contributions of individual Fzd proteins to osteoblast function, we profiled the express...

journal_title：Journal of cellular physiology

authors： Kushwaha P,Kim S,Foxa GE,Michalski MN,Williams BO,Tomlinson RE,Riddle RC

更新日期：2020-10-01 00:00:00

abstract：:Current osteoinductive protein therapy utilizes bolus administration of large doses of bone morphogenetic proteins (BMPs), which is costly, and may not replicate normal bone healing. The limited in vivo biologic activity of BMPs requires the investigation of growth factors that may enhance this activity. In this study...

journal_title：Journal of cellular physiology

authors： Arosarena OA,Del Carpio-Cano FE,Dela Cadena RA,Rico MC,Nwodim E,Safadi FF

更新日期：2011-11-01 00:00:00

abstract：:Mitochondrial (mt) dysfunction and oxidative stress are involved in the pathogenesis of ischemia/reperfusion (I/R)-injury. Lycopene, a lipophilic antioxidant found mainly in tomatoes and in other vegetables and fruits, can protect mtDNA against oxidative damage. However, the role of mtDNA in myocardial I/R-injury is u...

journal_title：Journal of cellular physiology

authors： Yue R,Xia X,Jiang J,Yang D,Han Y,Chen X,Cai Y,Li L,Wang WE,Zeng C

更新日期：2015-09-01 00:00:00

abstract：:Past work has shown that delta-opioid receptor (DOR) activation by [D-Ala(2),D-Leu(5)]-enkephalin (DADLE) attenuated the disruption of K(+) homeostasis induced by hypoxia or oxygen-glucose deprivation (OGD) in the cortex, while naltrindole, a DOR antagonist blocked this effect, suggesting that DOR activity stabilizes ...

journal_title：Journal of cellular physiology

authors： Chao D,Bazzy-Asaad A,Balboni G,Xia Y

更新日期：2007-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) is a small molecule (19-25 nucleotide) noncoding RNA that inhibits the expression of target messenger RNA (mRNA) at the posttranscriptional level as an endogenous regulator. There is an increasing evidence that miR-199a-3p has a significant effect on the development of multiple tumors. However, the ...

journal_title：Journal of cellular physiology

authors： Chen HP,Wen J,Tan SR,Kang LM,Zhu GC

更新日期：2019-12-01 00:00:00

abstract：:Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of this study was to dete...

journal_title：Journal of cellular physiology

authors： Redmond EM,Cahill PA,Hodges R,Zhang S,Sitzmann JV

更新日期：1996-03-01 00:00:00