Abstract:
:The etiology of endometriosis, a gynecological disease characterized by the presence of endometrial glands and stroma outside the uterine cavity, is still unknown. Our research group has recently demonstrated the presence of ectopic endometrium in human female fetuses at different gestational ages. In this manuscript we describe four new cases of fetal endometriosis found among a series of 52 female fetuses analyzed at autopsy. The anatomical localization of this ectopic endometrium, and its histological and immunohistochemical characteristics are depicted. We suggest that endometriosis is caused by dislocation of primitive endometrial tissue outside the uterine cavity during organogenesis. The clinical and pathological implications of these findings are discussed.
journal_name
J Cell Physioljournal_title
Journal of cellular physiologyauthors
Signorile PG,Baldi F,Bussani R,Viceconte R,Bulzomi P,D'Armiento M,D'Avino A,Baldi Adoi
10.1002/jcp.22888subject
Has Abstractpub_date
2012-04-01 00:00:00pages
1653-6issue
4eissn
0021-9541issn
1097-4652journal_volume
227pub_type
杂志文章abstract::The purpose of this study was to characterize the direct effects of uncarboxylated osteocalcin (ucOCN) on vascular cell biology in vitro, to assess its potential function in pathophysiological conditions such as atherosclerosis. Human aortic endothelial cells (HAECs) and smooth muscle cells (HASMCs) were treated with ...
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abstract::To determine if Chinese Hamster Ovary (CHO) cells in culture are able to metabolize steroids, CHO cells were incubated in defined medium with [14C]pregnenolone. As shown, [14C]pregnenolone is metabolized to progesterone and other delta 53 beta steroids; this steroidogenic response is appreciably enhanced upon exposure...
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更新日期:1992-03-01 00:00:00
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更新日期:2010-05-01 00:00:00
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