The adhesive glycoprotein laminin is an agglutinin.

abstract：:Heparin and related glycosaminoglycans are potent inhibitors of both in vivo and in vitro smooth muscle cell (SMC) proliferation. We have found that epidermal growth factor (EGF) reverses the antiproliferative effects of heparin. Other known SMC mitogens, including platelet-derived growth factor (PDGF), insulin-like g...

journal_title：Journal of cellular physiology

authors： Reilly CF,Fritze LM,Rosenberg RD

更新日期：1987-05-01 00:00:00

abstract：:MicroRNAs (miRNAs) is a small molecule (19-25 nucleotide) noncoding RNA that inhibits the expression of target messenger RNA (mRNA) at the posttranscriptional level as an endogenous regulator. There is an increasing evidence that miR-199a-3p has a significant effect on the development of multiple tumors. However, the ...

journal_title：Journal of cellular physiology

authors： Chen HP,Wen J,Tan SR,Kang LM,Zhu GC

更新日期：2019-12-01 00:00:00

abstract：:Sulfogalactosylglycerolipid (SGG) is the major mammalian male germ cell glycolipid and has been implicated in sperm/egg binding. Mycoplasma pulmonis, a species of Mollicutes, is associated with male infertility in rodents. Purified SGG incubated in the presence of M. pulmonis was enzymatically degraded by both desulfa...

journal_title：Journal of cellular physiology

authors： Lingwood C,Schramayr S,Quinn P

更新日期：1990-01-01 00:00:00

abstract：:Cells are quite sensitive to a change of the extracellular pH and respond to it through detection of the H+/HCO3- level in extracellular fluid. However, little is known about molecular details induced by acidosis, such as intracellular pathways and gene expression. Here we describe properties of gene expression, prote...

journal_title：Journal of cellular physiology

authors： Shimokawa N,Kumaki I,Qiu CH,Ohmiya Y,Takayama K,Koibuchi N

更新日期：2005-10-01 00:00:00

abstract：:Spontaneously arising, TGF beta 1-resistant colonies were isolated directly from the soft agarose plates of MOSER human colon carcinoma cells grown in the presence of TGF beta 1 but in the absence of serum. The colonies were cloned by limiting dilution and screened in a monolayer proliferation assay for sensitivity to...

journal_title：Journal of cellular physiology

authors： Zhou GH,Sechrist GL,Brattain MG,Mulder KM

更新日期：1995-12-01 00:00:00

abstract：:We have previously shown that Compound 5 (Cpd 5), an inhibitor of protein phosphatase Cdc25A, inhibits Hep3B human hepatoma cell growth. We now show that hepatocyte growth factor (HGF), a hepatocyte growth stimulant, can strongly enhance Cpd 5-induced growth inhibition in Hep3B cells, and this enhancement in cell grow...

journal_title：Journal of cellular physiology

authors： Wang Z,Wang M,Carr BI

更新日期：2005-06-01 00:00:00

abstract：:We have examined the effects of constitutive expression of PTHrP on the growth and differentiation of populations of cells derived from a clonal chondrocytic cell line, CFK2. Cells were stably transfected with cDNA encoding either full-length, secretory PTHrP (CFK2P) or nonsecretory PTHrP (CFK2P-SS). In cultures of ce...

journal_title：Journal of cellular physiology

authors： Henderson JE,He B,Goltzman D,Karaplis AC

更新日期：1996-10-01 00:00:00

abstract：:The signaling pathways that stimulate glucose uptake in response to muscle contraction are not well defined. Recently, we showed that carbachol, an acetylcholine analog, stimulates contraction of C2C12 myotube cultures and the rapid arrival of myc-epitope tagged GLUT4 glucose transporters at the cell surface. Here, we...

journal_title：Journal of cellular physiology

authors： Niu W,Bilan PJ,Yu J,Gao J,Boguslavsky S,Schertzer JD,Chu G,Yao Z,Klip A

更新日期：2011-01-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:Obesity, a rising public health burden, is a multifactorial disease with an increased risk for patients to develop several pathological conditions including type 2 diabetes mellitus, hypertension, and cardiovascular disease. Increasing evidence suggests a relationship between the human brain-derived neurotrophic facto...

journal_title：Journal of cellular physiology

authors： Ieraci A,Barbieri SS,Macchi C,Amadio P,Sandrini L,Magni P,Popoli M,Ruscica M

更新日期：2020-12-01 00:00:00

abstract：:The growth-regulated vimentin gene contains a functional double AP-1 binding site formed by two nearly perfect inverted repeats. We present evidence for down-regulation of vimentin expression by the retinoic acid receptor (RAR) in two mesodermally derived cell types. By mutation analysis we prove that the double conse...

journal_title：Journal of cellular physiology

authors： Van de Klundert FA,Jansen HJ,Bloemendal H

更新日期：1995-07-01 00:00:00

abstract：:Mouse heptoma cells that secrete large amounts of alpha-fetoprotein (AFP) and albumin have been crossed with rat hepatoma cells that secret only albumin, and in relatively small amounts, to investigate the influence of each parental genome upon the expression of serum proteins. All of the ten independent hybrid clones...

journal_title：Journal of cellular physiology

authors： Cassio D,Hassoux R,Dupiers M,Uriel J,Weiss MC

更新日期：1980-09-01 00:00:00

abstract：:An isoform of the Na(+)/Ca(2+) exchanger (SDNCX1.10) was cloned from mesangial cells of Sprague-Dawley rat. Regulation of this isoform was compared to two other clones that were derived from the Dahl/Rapp salt sensitive (SNCX) and salt resistant rat (RNCX). All isoforms differ at the alternative splice site and at ami...

journal_title：Journal of cellular physiology

authors： Williams I,Williams C,Siroky B,Bates E,Kovacs G,Peti-Peterdi J,Unlap MT,Bell PD

更新日期：2004-05-01 00:00:00

abstract：:Proprotein convertase subtilisin/kexin 4 (PCSK4) is implicated for sperm fertilizing ability, based on studies using Pcsk4-null mice. Herein we demonstrated proprotein convertase (PC) activity in intact sperm and acrosomal vesicles. To determine whether this activity was important for sperm fertilizing ability, a pept...

journal_title：Journal of cellular physiology

authors： Iamsaard S,Vanichviriyakit R,Hommalai G,Saewu A,Srakaew N,Withyachumnarnkul B,Basak A,Tanphaichitr N

更新日期：2011-11-01 00:00:00

abstract：:Maintenance of intestinal epithelial barrier functions is crucial to prevent systemic contamination by microbes that penetrate from the gut lumen. GTPases of the Rho-family such as RhoA, Rac1, and Cdc42 are known to be critically involved in the regulation of intestinal epithelial barrier functions. However, it is sti...

journal_title：Journal of cellular physiology

authors： Schlegel N,Meir M,Spindler V,Germer CT,Waschke J

更新日期：2011-05-01 00:00:00

abstract：:The SV40 transformed murine macrophage cell line, BAC1, proliferates in response to the colony stimulating factor, CSF-1 (Schwarzbaum et al., J. Immunol., 132:1158, 1984). In order to obtain a cell line suitable for biochemical and genetic studies of CSF-1 signal transduction, clones of BAC1 were established. Clones r...

journal_title：Journal of cellular physiology

authors： Morgan C,Pollard JW,Stanley ER

更新日期：1987-03-01 00:00:00

abstract：:Glutamine (gln) is the most abundant free amino acid in the blood. It is involved in important metabolic and biochemical processes, like cell proliferation and oxidative stress. Previous studies have demonstrated that gln concentration in human plasma decreases in several conditions such as sepsis, ischemia-reperfusio...

journal_title：Journal of cellular physiology

authors： Viggiano E,Passavanti MB,Pace MC,Sansone P,Spaziano G,Viggiano A,Aurilio C,Monda M,Viggiano A,Pota V,De Luca B,De Luca E

更新日期：2012-05-01 00:00:00

abstract：:Numerous studies have reported that long noncoding RNA (lncRNA) dysregulation is involved in the progression of many malignant tumors, including glioma. The lncRNA ZNFX1 antisense RNA 1 (ZFAS1) plays an oncogenic role in various malignant tumors, such as gastric cancer and hepatocellular carcinoma. However, the underl...

journal_title：Journal of cellular physiology

authors： Li X,Luo Y,Liu L,Cui S,Chen W,Zeng A,Shi Y,Luo L

更新日期：2020-03-01 00:00:00

abstract：:Controlled-release drug delivery systems are promising platforms in medicine. Among various types of material in drug delivery, hydrogels are interesting ones. They are water-soluble and tissue compatible polymers with a high capacity to carry and release drugs in a controllable manner. In this study, we introduce the...

journal_title：Journal of cellular physiology

authors： Davoodi-Monfared P,Akbari-Birgani S,Mohammadi S,Kazemi F,Nikfarjam N,Nikbakht M,Mousavi SA

更新日期：2020-11-05 00:00:00

abstract：:Prostate cancer (PCa) is the second leading cause of death among American men. Increasing evidence has shown that long noncoding RNAs (lncRNAs) play important roles in tumorigenesis of PCa. In this study, we explored the biological functions of small nucleolar RNA host gene 12 (SNHG12) and investigated the interaction...

journal_title：Journal of cellular physiology

authors： Cheng G,Song Z,Liu Y,Xiao H,Ruan H,Cao Q,Wang K,Xiao W,Xiong Z,Liu D,Chen K,Zhang X

更新日期：2020-02-01 00:00:00

abstract：:Cystamine together with colchicine markedly enhanced the uptake of [3H]-thymidine into DNA of quiescent cultures of insulin-stimulated Swiss 3T3 mouse fibroblasts. Flow cytofluorometric analyses showed an increased rate of transition of cells from G0/G1----S + G2 in response to combinations of insulin, colchicine, and...

journal_title：Journal of cellular physiology

authors： Fong S,Friedkin M

更新日期：1984-09-01 00:00:00

abstract：:Schizophrenia (SZ) is characterized by a high morbidity and disability rate and has gradually increased in rate and caused much burden. However, the pathogenesis of SZ is elusive and may include changes in the biological molecules in exosomes. In this study, we first compared the alterations of plasma exosomal circula...

journal_title：Journal of cellular physiology

authors： Tan G,Wang L,Liu Y,Zhang H,Feng W,Liu Z

更新日期：2021-01-01 00:00:00

abstract：:Extracellular high K(+) (75 mM) increased intracellular Ca(2+) concentrations in cultured rat hippocampal astrocytes, and the Ca(2+) rise was abolished by deleting extracellular Ca(2+) or cadmium, a non-selective inhibitor of voltage-dependent calcium channels (VDCCs). In the reverse transcription-polymerase chain rea...

journal_title：Journal of cellular physiology

authors： Yaguchi T,Nishizaki T

更新日期：2010-11-01 00:00:00

abstract：:Matrix metalloproteinase-2 (MMP-2) is best understood for its biological actions outside the cell. However, MMP-2 also localizes to intracellular compartments and the cytosol where it has several substrates, including troponin I (TnI). Despite a growing list of cytosolic substrates, we currently do not know the mechan...

journal_title：Journal of cellular physiology

authors： Ali MA,Chow AK,Kandasamy AD,Fan X,West LJ,Crawford BD,Simmen T,Schulz R

更新日期：2012-10-01 00:00:00

abstract：:The correspondence between K+ uptake in platelets to their responsiveness was studied using 86Rb+ as an analogue of K+. An average 86Rb+ uptake rate of 0.73 (+/- 0.140) x 10(-15) mole Rb+/min-plt (n = 20) was observed. By the use of K(+)-influx inhibitors, we were able to distinguish three distinct 86Rb+ uptake pathwa...

journal_title：Journal of cellular physiology

authors： Marx G,Blankenfeld A,Panet R,Gorodetsky R

更新日期：1992-05-01 00:00:00

abstract：:Hyperthermia is a clinical sign of inflammation and constitutes in itself an adaptive defense mechanism. The fibrinolytic system, a highly regulated proteolytic system, is involved in inflammatory processes. Plasminogen activator inhibitor 1 (PAI-1) is the principal inhibitor of the two activators of the fibrinolytic ...

journal_title：Journal of cellular physiology

authors： Bergonzelli GE,Kruithof EK

更新日期：1991-08-01 00:00:00

abstract：:Indoleamine 2,3-dioxygenase (IDO), a tryptophan degrading enzyme, is a potent immunomodulatory factor. IDO expression in fibroblasts selectively induces apoptosis in immune cells but not in primary skin cells. However, the mechanism(s) of this selective effect of IDO-induced low tryptophan environment is not elucidate...

journal_title：Journal of cellular physiology

authors： Habibi D,Jalili RB,Forouzandeh F,Ong CJ,Ghahary A

更新日期：2010-10-01 00:00:00

abstract：:In vitro generation of HSCs from pluripotent stem cells (PSCs) can be regarded as novel therapeutic approaches for replacing bone marrow (BM) transplantation without immune rejection or graft versus host disease(GVHD). To date, many differentiation approaches have been evaluated in terms of directing PSCs toward diffe...

journal_title：Journal of cellular physiology

authors： Shan W,Wang B,Xu Y,Li X,Li X,Wang H,Lin Y,Tie R,Zhao Q,Wang J,Zheng W,Hu Y,Shi J,Yu X,Huang H

更新日期：2018-01-31 00:00:00

abstract：:Alpha-D-galactose is metabolized in species ranging from E. coli to mammals predominantly via a series of sequential reactions collectively known as the Leloir pathway. Deficiency of any one of these enzymes in humans results in a form of the inherited metabolic disorder, galactosemia, although the symptoms and severi...

journal_title：Journal of cellular physiology

authors： Fridovich-Keil JL

更新日期：2006-12-01 00:00:00

abstract：:The coupled action of the Na(+)/H(+) exchanger NHE1 and the HCO3(-)/Cl(-) exchanger AE2 constitutes the principal mechanism for acute correction of decreased cell volume in mammalian somatic cells, while, when acting separately, they regulate intracellular pH. It was previously found that AE2 becomes inactivated durin...

journal_title：Journal of cellular physiology

authors： Zhou C,Fitzharris G,Alper SL,Baltz JM

更新日期：2013-10-01 00:00:00