Abstract:
:The field of tissue engineering has developed in phases: initially researchers searched for "inert" biomaterials to act solely as replacement structures in the body. Then, they explored biodegradable scaffolds--both naturally derived and synthetic--for the temporary support of growing tissues. Now, a third phase of tissue engineering has developed, through the subcategory of "regenerative medicine." This renewed focus toward control over tissue morphology and cell phenotype requires proportional advances in scaffold design. Discoveries in nanotechnology have driven both our understanding of cell-substrate interactions, and our ability to influence them. By operating at the size regime of proteins themselves, nanotechnology gives us the opportunity to directly speak the language of cells, through reliable, repeatable creation of nanoscale features. Understanding the synthesis of nanoscale materials, via "top-down" and "bottom-up" strategies, allows researchers to assess the capabilities and limits inherent in both techniques. Urology research as a whole, and bladder regeneration in particular, are well-positioned to benefit from such advances, since our present technology has yet to reach the end goal of functional bladder restoration. In this article, we discuss the current applications of nanoscale materials to bladder tissue engineering, and encourage researchers to explore these interdisciplinary technologies now, or risk playing catch-up in the future.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Harrington DA,Sharma AK,Erickson BA,Cheng EYdoi
10.1007/s00345-008-0273-0subject
Has Abstractpub_date
2008-08-01 00:00:00pages
315-22issue
4eissn
0724-4983issn
1433-8726journal_volume
26pub_type
杂志文章,评审abstract:PURPOSE:To reach standardized terminology in focal therapy (FT) for prostate cancer (PCa). METHODS:A four-stage modified Delphi consensus project was undertaken among a panel of international experts in the field of FT for PCa. Data on terminology in FT was collected from the panel by three rounds of online questionna...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-016-1782-x
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:Digital low-dosage, linear slot scanning radiography (Lodox®) is an imaging modality that can emit down to one-tenth the radiation of conventional X-ray systems. We prospectively evaluated Lodox® as a diagnostic imaging modality in patients with ureterolithiasis. METHODS:Conventional kidney-ureter-bladder (KUB...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02803-w
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:As silodosin 8 mg, used for treating BPH, is known to cause absence of sperms in the ejaculate, its potential as an on-demand, reversible, nonhormonal oral contraceptive for males was assessed in this pilot study. METHODS:In this randomized, double-blind, placebo-controlled pilot study, healthy, sexually activ...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-019-02806-7
更新日期:2020-03-01 00:00:00
abstract::Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent in men than in women. We review the main established/proposed factors, both environmental and genetic, associated with bladder cancer etiology and prognosis. Data were extracted from previous reviews and original articles ident...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0168-5
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:Robotic radical prostatectomy claims optimal oncologic results, minimal morbidity and best outcomes of urinary continence and erection function. Potential benefits concerning side effects and complications compared to open radical prostatectomy are analysed. METHODS:Out of 450 robotic radical prostatectomie...
journal_title:World journal of urology
pub_type: 杂志文章,meta分析,多中心研究
doi:10.1007/s00345-008-0287-7
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:Urinary tract infection (UTI) is the most common bacterial infection among infectious complications in kidney transplant recipients (KTR). After transplantation, infections can result from surgical complications, donor-derived infections, pre-existing recipient infections, and nosocomial infections. Post-transp...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03173-4
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To analyse the surgical margins status of prostatic glands, resected by laparoscopic radical prostatectomy (LRP) for prostate cancer, and to correlate it with biochemical free survival rate (BFSR). METHODS:Data were collected prospectively from 405 patients undergoing LRP from 2000 to 2009 at a single institut...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0711-2
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To compare prospectively early outcome and complications of catheter removal after robot-assisted radical prostatectomy (RARP) on the 4th or 7th day with a standardized running barbed suture technique. INTRODUCTION:The time point of removing the indwelling catheter after RARP mainly depends on institute's/su...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-03001-4
更新日期:2020-09-01 00:00:00
abstract::Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. The current indications for the surgical correction of VUR depend on the presence or absence of renal scars. If no scars are present, primary ureteral reimplantation is only indicated in high-grade bil...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0408-x
更新日期:2004-06-01 00:00:00
abstract::The aim of this project was to evaluate the ice-water test as a predictor of the response to intradetrusor botulinum toxin injection in patients with neurogenic detrusor overactivity. We retrospectively evaluated the urodynamic parameters in 22 patients with neurogenic bladder dysfunction and positive ice-water test. ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-007-0208-1
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To compare serial changes of postoperative storage symptoms between PVP and HoLEP, and to identify the predictors influencing postoperative improvement of storage symptoms. METHODS:A total of 486 men (PVP group: 213 cases; HoLEP group: 273 cases), in whom 12-month follow-up data were available, were included i...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1424-0
更新日期:2015-08-01 00:00:00
abstract::Local recurrent prostate cancer after radical treatment is found in the majority of men with a rising PSA. Salvage treatment procedures for recurrent disease, such as radiation therapy and ablative procedures, can provide long-term responses in well-selected cases. Prostate magnetic resonance imaging (MRI) allows diag...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-02677-y
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To investigate, if and how omitting gadolinium-based contrast agents (GBCA) and dynamic contrast-enhanced imaging (DCE) influences diagnostic accuracy and tumor detection rates of prostate MRI. METHODS:In this retrospective study, 236 patients were included. The results of biparametric (bpMRI) and multiparamet...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2428-y
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:The objective of our study was to study trainees' feedback and rating of models for training transurethral resection of bladder lesions (TURBT) and prostate (TURP) during simulation. METHODS:The study was performed during the ''Transurethral resection (TUR) module" at the boot camp held in 2019. Prior to th...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03559-4
更新日期:2021-01-04 00:00:00
abstract::Nephrolithiasis is a highly prevalent disease worldwide with rates ranging from 7 to 13% in North America, 5-9% in Europe, and 1-5% in Asia. Due to high rates of new and recurrent stones, management of stones is expensive and the disease has a high level of acute and chronic morbidity. The goal of this study is to rev...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-017-2008-6
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Making healthcare treatment decisions is a complex process involving a broad stakeholder base including patients, their families, health professionals, clinical practice guideline developers and funders of healthcare. METHODS:This paper presents a review of a methodology for the development of urological ca...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0660-9
更新日期:2011-06-01 00:00:00
abstract::Our objectives were to ascertain the tolerability and efficacy of trospium chloride in doses of 20 mg twice daily for long-term therapy (52 weeks) in patients with urge syndrome. The trial comprised a total of 358 patients with urge syndrome or urge incontinence. After randomisation in the ratio of 3:1, participants w...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/s00345-003-0321-8
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:Vesico-ureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Surgery is an important part of its management. Laparoscopic ureteric reimplantation using the Lich-Gregoir technique is an option for VUR. The aim of this study is to assess short- and medium-...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2064-y
更新日期:2017-11-01 00:00:00
abstract::Although anejaculation is a relatively uncommon occurrence in the general population, over 12,000 new cases are reported annually. Anejaculation may result from spinal cord injury (SCI), retroperitoneal lymph node dissection (RPLND), diabetes mellitis, transverse myelitis, multiple sclerosis, or psychogenic disorders....
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF00182035
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Few studies have been conducted on the serial evaluation of predictors for recovery of urinary continence (RC) after radical prostatectomy (RP) among same cohort. We developed and validated nomograms to predict immediate (≤1), early (≤3), and late (≤12 months) RC from a contemporary series and compared each nom...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-013-1127-y
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Radiation for tumors arising in the pelvis has been utilized for over a 100 years. Adverse effects (AEs) of radiotherapy (RT) continue to accumulate with time and are reported to show decades after treatment. The benefit of RT for pelvic tumors is well described as is their acute AEs. Late AEs are less well d...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-010-0603-x
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:Although the role of lymph node dissection (LND) is well defined in many urological settings, uncertainty regarding need for LND still exists for patients with renal cell carcinoma (RCC). The aim of the current review is to highlight the rationale for performing or omitting LND at the time of renal surgery. ME...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-016-1886-3
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:Erectile dysfunction (ED) is an early sign of vascular dysfunction. Studies have reported a correlation between arterial stiffness and cardiovascular events. The objective of this study was to evaluate the association among different criteria for assessing arterial stiffness and cardiovascular risk factors in E...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-009-0486-x
更新日期:2010-10-01 00:00:00
abstract::Robotic surgery was started in the Department of Urology, Hospital Kuala Lumpur, in April 2004. We present our experience in developing the program and report the results of our first 50 cases of robotic radical prostatectomy. A three-arm da Vinci robotic system was installed in our hospital in March 2004. Prior to in...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0069-z
更新日期:2006-06-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:The possibility of performing remote-surgery has been the goal to achieve, since the early development of the first surgical robotic platforms. This systematic review aims to analyse the state of the art in the field and to provide an overview of the possible growth of this technology. METH...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02996-0
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:We aimed to investigate the association between nocturia and serum metabolites identified using metabolomics analysis. METHODS:This study enrolled 66 men aged 65-80 years, recruited from the outpatient department of a university hospital. The participants were stratified as follows: Nocturia group [45 men with...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02647-4
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVES:Adjuvant chemotherapy (ACT) is recommended for non-organ-confined bladder cancer (BCa) after radical cystectomy (RC) and pelvic lymph node dissection (PLND), but there are sparse data regarding its specific efficacy in patients with histological variants. The aim of our study was to evaluate the role of ACT ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03362-1
更新日期:2020-07-25 00:00:00
abstract:OBJECTIVE:To provide most recent and high quality evidence concerning the comparison between monopolar and bipolar transurethral resection of non-muscle invasive bladder tumors. MATERIALS AND METHODS:Two researchers performed a systematic review of the current literature independently, to identify studies published in...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03313-w
更新日期:2020-06-26 00:00:00
abstract::The treatment of clinically locally advanced prostate cancer (cT3-4) is subject to controversies. Patients with lymph node metastases as well as patients with overstaged localized and thus curable disease fall into this category. Radical prostatectomy, external beam radiotherapy and early or deferred hormonal therapy ...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0158-7
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To prospectively compare short-term functional outcomes achieved by laparoscopic or robot-assisted sacrocolpopexy for pelvic organ prolapse. MATERIALS AND METHODS:We prospectively collected clinical and operative data over 24 months for female patients who underwent either pure laparoscopic sacrocolpopexy (L...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0748-2
更新日期:2012-06-01 00:00:00