Abstract:
PURPOSE:Digital low-dosage, linear slot scanning radiography (Lodox®) is an imaging modality that can emit down to one-tenth the radiation of conventional X-ray systems. We prospectively evaluated Lodox® as a diagnostic imaging modality in patients with ureterolithiasis. METHODS:Conventional kidney-ureter-bladder (KUB) X-ray and Lodox® were performed in 41 patients presenting with acute flank pain due to unilateral ureteral stone confirmed by computed tomography. KUB X-ray and Lodox® images were then reviewed by four blinded readers (urology expert/resident, radiology expert/resident). Identification rates were compared using Pearson's Chi square test. The impact of different parameters on stone identification by Lodox® was evaluated using logistic regression and generalized linear mixed models. Inter-reader agreement was tested using Cohen's kappa coefficient. RESULTS:Median stone size was 5 mm (range 2-12), median stone density was 800 HU (range 200-1500). The identification rates of the urology expert were 68% for KUB X-ray and 90% for Lodox® (p = 0.014), and for all four readers 61% for KUB X-ray and 62% for Lodox® (p = 0.8). Radiation exposure for KUB X-ray and Lodox® was 0.45 mSv (SD ± 0.64) and 0.027 mSv (SD ± 0.038), respectively. Multivariable analyses showed an association between stone identification by Lodox® and stone size (p < 0.001), stone density (p = 0.005), lower body mass index (p = 0.005), and reader (p < 0.001). CONCLUSIONS:The high identification rates and low radiation doses of Lodox® make it a promising imaging modality for the diagnosis of ureteral stones. Further validation in larger cohorts, including performance evaluation for renal stones, is warranted. TRIAL REGISTRATION:http://www.controlled-trails.com/ISRCTN12915426.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Fiechter S,Geissbühler E,Bähler A,Obmann V,Meierhans S,Exadaktylos AK,Christe A,Thalmann GN,Roth Bdoi
10.1007/s00345-019-02803-wsubject
Has Abstractpub_date
2020-04-01 00:00:00pages
1065-1071issue
4eissn
0724-4983issn
1433-8726pii
10.1007/s00345-019-02803-wjournal_volume
38pub_type
杂志文章abstract:PURPOSE:To analyse the surgical margins status of prostatic glands, resected by laparoscopic radical prostatectomy (LRP) for prostate cancer, and to correlate it with biochemical free survival rate (BFSR). METHODS:Data were collected prospectively from 405 patients undergoing LRP from 2000 to 2009 at a single institut...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0711-2
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:A paucity of data exists on the insignificant disease potentially suitable for active surveillance (AS) among men with intermediate-risk prostate cancer (PCa). We tried to identify pathologically insignificant disease and its preoperative predictors in men who underwent radical prostatectomy (RP) for intermedia...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1413-3
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To compare oncological, functional, and toxicity outcomes of patients with radiation-recurrent prostate cancer (PCa) after external beam radiation therapy (EBRT) or brachytherapy (BT) treated with salvage high-intensity focused ultrasound (S-HIFU) or salvage radical prostatectomy (S-RP). METHODS:This retrospec...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02640-x
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Metastatic renal cell carcinoma (mRCC) represents a significant and rising burden of disease, with rapidly evolving treatment modalities. The role of cytoreductive nephrectomy (CN) is controversial in this setting. As such, London Cancer has pursued a multidisciplinary team (MDT) approach when assessing suitabi...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03107-0
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:68Ga-PSMA Positron Emission Tomography/Computerized Tomography (PET/CT) has shown promising results for the detection of recurrent prostate cancer (RPCa). However, the diagnostic value of this method is yet to be validated. The aim of this study was to determine the influence of clinical and biochemical vari...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2460-y
更新日期:2019-05-01 00:00:00
abstract::The diagnosis of prostate cancer is based on histology. Prostate biopsies are obtained based on the triad of prostate specific antigen (PSA), digital rectal examination (DRE) and transrectal ultrasound. Because prostate biopsies still have a large percentage of negative outcomes, patient selection and biopsy direction...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0189-0
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To characterize the clinical and pathologic staging of patients with urothelial carcinoma (UC) in bladder diverticula (BD) after undergoing radical cystectomy (RC) and determine the impact of UCBD on recurrence and survival. METHODS:We reviewed our institutional database of patients who underwent RC for UC (19...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1472-5
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:Neurogenic bladder due to spinal cord injury has significant consequences for patients' health and quality of life. Regular surveillance is required to assess the status of the upper and lower urinary lower urinary tracts and prevent their deterioration. In this review, we examine surveillance techniques in neu...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-018-2345-0
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To explore the role of prostate biopsy core length on prediction of index tumor clinical significance and localization on radical prostatectomy (RP) and time to recurrence, hypothesizing 10-, 10-12-, or > 12-mm minimum core as potential biopsy quality control. METHODS:Assessed 2424 prostate biopsy cores and co...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2242-6
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:We sought whether serum total testosterone (tT), estradiol (E2), tT/E2 ratio, and sex hormone-binding globulin (SHBG) significantly fluctuate throughout time in men with prostate cancer (PCa). METHODS:Circulating hormones were measured in a cohort of 631 candidates for radical prostatectomy. Hormone levels wer...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-1009-8
更新日期:2013-04-01 00:00:00
abstract::Many human tumors such as bladder carcinoma that are initially responsive to chemotherapy eventually fail to respond to treatment. For most drugs, dose escalation that may be required for a cure cannot be achieved because sensitive tissues such as bone marrow limit cytotoxic therapy. Approaches to prevent or circumven...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF00184246
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:The perioperative and oncological outcomes of laparoscopic radical nephrectomy (LRN) for T1-T2 renal cell carcinoma (RCC) are well established. We aim to determine whether LRN is a comparable alternative to open radical nephrectomy (ORN) in the treatment of T3 RCC using a matched pair analysis study design. ME...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1280-y
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as a relatively cost-effective additional tool. METHODS:We highlight the advantages of disease regis...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0658-3
更新日期:2011-06-01 00:00:00
abstract::Robotic surgery was started in the Department of Urology, Hospital Kuala Lumpur, in April 2004. We present our experience in developing the program and report the results of our first 50 cases of robotic radical prostatectomy. A three-arm da Vinci robotic system was installed in our hospital in March 2004. Prior to in...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0069-z
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:The prostate-specific antigen density (PSAD) helps distinguish between benign prostatic hyperplasia (BPH) and prostate cancer. Accurate prostate volume (PV) assessment is necessary for PSAD calculation and both BPH diagnosis and treatment response monitoring; therefore, accurate PV measurement is increasingly b...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-013-1220-2
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Erectile dysfunction (ED) is an early sign of vascular dysfunction. Studies have reported a correlation between arterial stiffness and cardiovascular events. The objective of this study was to evaluate the association among different criteria for assessing arterial stiffness and cardiovascular risk factors in E...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-009-0486-x
更新日期:2010-10-01 00:00:00
abstract:INTRODUCTION:Percutaneous stone removal increasingly plays an important role among the different approaches of interventional stone therapy, particularly since the development of miniaturized instruments is resulting in lower morbidity for the patients. One major drawback of smaller instruments is the increased difficu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1541-4
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To assess whether real-time elastography-targeted biopsy (RTE-bx) is superior to the standard systematic transrectal ultrasound (TRUS)-guided biopsy in predicting subsequent prostate cancer (PCa) rates in patients with initially negative biopsy and to specifically reveal differences in the occurrence of high-gr...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2178-x
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:To investigate the effects of onabotulinum toxin type A (Onabot/A) intravesical injections on urinary and sexual function in a group of patients affected by multiple sclerosis (MS). METHODS:We enrolled 31 MS female patients with symptoms of overactive bladder and detrusor overactivity. All patients underwent u...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章
doi:10.1007/s00345-015-1578-4
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Evidence suggests that both selenium and vitamin E reduce the risk of prostate cancer. The Selenium and Vitamin E Cancer Prevention Trial (SELECT) is a randomized, prospective, double-blind study designed to determine whether selenium and vitamin E alone and in combination can reduce the risk of prostate can...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-002-0314-z
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To assess the feasibility, safety, and outcomes of an expedited One-Stop prostate cancer (PCa) diagnostic pathway. PATIENTS AND METHODS:We identified 370 consecutive patients who underwent multiparametric magnetic resonance imaging (mpMRI) and transrectal ultrasound fusion prostate biopsy (MRI/TRUS-PBx) from o...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02835-2
更新日期:2020-04-01 00:00:00
abstract::Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent in men than in women. We review the main established/proposed factors, both environmental and genetic, associated with bladder cancer etiology and prognosis. Data were extracted from previous reviews and original articles ident...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0168-5
更新日期:2007-06-01 00:00:00
abstract::A low-pressure reservoir for urine is created by antimesenteric splitting and side-to-side anastomosis of the rectosigmoid, the expectation being to obtain better continence rates and better protection of the upper tract than are achievable by ureterosigmoidostomy. Between 1990 and August 1993 the procedure was perfor...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00182560
更新日期:1996-01-01 00:00:00
abstract::The development of human benign prostatic hyperplasia (BPH) clearly requires a combination of testicular androgens and the ageing process. Although the role of androgens as the causative factor for human benign prostatic hyperplasia is debated, they undoubtedly play, at least, a permissive role. The principal prostati...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-002-0248-5
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:To assess long-term clinical and oncological outcome in women undergoing radical cystectomy and ileal neobladder reconstruction for invasive bladder cancer. METHODS:From 1995 to 2010, a total of 121 women with clinically organ-confined urothelial carcinoma underwent radical cystectomy with an orthotopic ileal ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0837-x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To report our experience with pelvic reconstructive surgery with transobturator mesh implants in elderly women. MATERIALS AND METHODS:A total of 32 women aged >75 years with pelvic organ prolapse receiving anterior and/or posterior repair using transobturator mesh implants were included. Concomitant mid-urethr...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0863-8
更新日期:2013-06-01 00:00:00
abstract::Due to its unique biological behavior, late relapse (LR) of testicular cancer has recently been described as an own tumor entity. It is currently defined as tumor recurrence more than 2 years after complete remission following primary treatment including chemotherapy. The incidence ranges from 2 to 6%, with a median r...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0397-9
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To assess the impact of HA on robotic PN (RPN) outcomes. METHODS:We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patien...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-015-1537-0
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To review current practices in manual bladder washouts (MBW) for haematuria with clot retention, comparing those conducted by a urology unit to other inpatient services. Secondly, to describe a standardised protocol for MBWs. METHODS:Prospective data were collected for patients treated for clot retention, from...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2346-z
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To evaluate the still controversially discussed prognostic role of preoperative platelet level (PPL) and thrombocytosis (TC) in patients who undergo surgery for renal cell carcinoma (RCC) based on the largest patient series reported to date. METHODS:A total of 3,139 patients, who underwent radical or nephron-s...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-012-0931-0
更新日期:2013-10-01 00:00:00