Abstract:
INTRODUCTION:Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as a relatively cost-effective additional tool. METHODS:We highlight the advantages of disease registries focusing on the example of prostate cancer and the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE™) registry. RESULTS:CaPSURE collects approximately 1,000 clinical and patient-reported variables, in over 13,000 men that are enrolled. Thus far, CaPSURE has yielded over 130 peer-reviewed publications, with several others in press, in key areas of risk migration, practice patterns, outcome prediction, and quality of life outcomes. CONCLUSIONS:Disease registries, like CaPSURE complement RCTs and CaPSURE, have provided a means to better understand many aspects of prostate cancer epidemiology, practice patterns, oncologic and HRQOL outcomes, and costs of care across populations. Specialized observational disease registries such as CaPSURE provide insight and have broad implications for disease management and policy.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Porten SP,Cooperberg MR,Konety BR,Carroll PRdoi
10.1007/s00345-011-0658-3subject
Has Abstractpub_date
2011-06-01 00:00:00pages
265-71issue
3eissn
0724-4983issn
1433-8726journal_volume
29pub_type
杂志文章abstract::Non-gonococcal urethritis (NGU) is conventionally treated with oral antibiotics. With this Phase II study, we investigated the action of a locally disinfecting substance, Instillagel, in symptomatic NGU. Instillation treatment was performed twice daily to 32 male patients with symptomatic NGU. To evaluate the therapeu...
journal_title:World journal of urology
pub_type: 临床试验,杂志文章
doi:10.1007/s00345-001-0236-1
更新日期:2002-05-01 00:00:00
abstract::The surgical complications encountered in 478 patients who underwent primary retroperitoneal lymph-node dissection for clinical stage A and B nonseminomatous testicular cancer during the period ranging from 1982 to 1992 were reviewed. There were 54 complications in 51 patients (10.6%), and there was no surgery-related...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00192272
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Squamous cell carcinoma (SCC) of the penis with inguinal lymph node involvement aggravates prognosis and can cause femoral artery bleeding, hemorrhagic shock and even death. The objective of this study is to describe the use of extra-anatomical transobturator bypass graft for femoral artery involvement by me...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0282-z
更新日期:2008-10-01 00:00:00
abstract::The widespread use of measurement of prostate-specific antigen for prostate cancer screening has led to a dramatic increase in the number of transrectal biopsies. Although transrectal ultrasound-guided prostate biopsy is the gold standard in the diagnosis of prostate cancer, the strategies for initial and repeat biops...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0151-1
更新日期:2007-03-01 00:00:00
abstract::Radical cystectomy with pelvic lymph node dissection has been accepted as the standard treatment for muscle-invasive bladder cancer. Radiation therapy and chemotherapy are increasingly being implemented in bladder-preservation protocols to provide an alternative treatment to cystectomy. We review experience with radia...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-002-0276-1
更新日期:2002-08-01 00:00:00
abstract:PURPOSE:The introduction of robotic surgical technology into urological reconstruction, particularly pediatrics, has introduced new horizons for reducing the morbidity and enhancing the efficacy of surgical repair of congenital conditions in children. In reviewing the evolution of pediatric urological applications of r...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02753-3
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:The purpose this study is to evaluate the efficacy of multiparametric ultrasound-targeted biopsies in patients undergoing initial biopsy of the prostate for the suspicion of prostate cancer. MATERIALS AND METHODS:A total of 167 patients who are biopsy naïve underwent multiparametric ultrasound-targeted biopsy ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2187-9
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To assess long-term clinical and oncological outcome in women undergoing radical cystectomy and ileal neobladder reconstruction for invasive bladder cancer. METHODS:From 1995 to 2010, a total of 121 women with clinically organ-confined urothelial carcinoma underwent radical cystectomy with an orthotopic ileal ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0837-x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:MicroRNAs (miRNAs) play an important role as regulators of gene expression in tumourigenesis by controlling many biological processes in growth, development, differentiation and apoptosis. Previous studies have shown an altered expression of specific miRNAs in clear cell renal cell carcinoma (ccRCC). But the fu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0633-4
更新日期:2011-06-01 00:00:00
abstract::It is well established that transmitters of the nonadrenergic-noncholinergic (NANC) system are involved in the control of sexual arousal and penile erection in healthy males. The proerectile activity of dopamine D1/D2 receptor agonist apomorphine-HCl (IXENSE, UPRIMA) involves oxytocinergic pathways descending from the...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-002-0300-5
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To evaluate the role of adrenergic and nitrergic signaling on ureteric peristaltic frequency and contraction force in vivo using a large animal model. METHODS:Twelve female pigs (72 ± 4 kg) were chronically instrumented with an electronic pressure-monitoring catheter in the right ureter. Nephrostomy, cystostom...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1663-8
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:To reach standardized terminology in focal therapy (FT) for prostate cancer (PCa). METHODS:A four-stage modified Delphi consensus project was undertaken among a panel of international experts in the field of FT for PCa. Data on terminology in FT was collected from the panel by three rounds of online questionna...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-016-1782-x
更新日期:2016-10-01 00:00:00
abstract::Pyeloplasty for congenital ureteropelvic junction (UPJ) obstruction enjoys a 90-95% success rate. Although treatment of the failed pyeloplasty has been addressed in the literature, management of the poorly draining or nondraining renal unit in the immediate postoperative period has not received any attention. For this...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00183119
更新日期:1996-01-01 00:00:00
abstract::The treatment options for patients with advanced prostate cancer are limited. Because of recent advances in the understanding of the molecular biology of prostate cancer, the accessibility of the prostate for injection, and the availability of gene promotors that allow tissue-specific expression of therapeutic gene pr...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050187
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVE:Bladder cancer (BC) has the highest lifetime treatment costs per patient of all cancers. The high recurrence rate and ongoing invasive monitoring requirement are the key contributors to the economic and human toll of this disease. The purpose of this paper was to utilize the recent literature to identify oppo...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-009-0395-z
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Dhat syndrome (DS) consists of vague somatic symptoms and at times sexual dysfunction which the patient falsely attributes to involuntary emissions of semen outside of sexual relations. OBJECTIVE:Describe and analyse the occurrences of DS in patients attending the clinic and clarify the existence of this co...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0911-4
更新日期:2013-08-01 00:00:00
abstract::Percutaneous nephrolithotomy (PCNL) remains the treatment of choice for staghorn renal calculi. Many reports suggest that laparoscopy can be an alternative treatment for large renal stones. We wished to evaluate the role and feasibility of laparoscopic extended pyelolithotomy (REP) for treatment of staghorn calculi. T...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0099-6
更新日期:2006-06-01 00:00:00
abstract::The aim of this cross-sectional study was to compare single with repeated high-intensity focused ultrasound (HIFU) treatment in patients with localized prostate cancer, regarding treatment-related morbidity. A number of 223 consecutive patients with localized prostate cancer were treated with HIFU. Among them, 174 (78...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0107-x
更新日期:2006-11-01 00:00:00
abstract::This paper provides an overview of the scientific and practical aspects of assessing health-related quality of life (HRQL). The paper provides a brief overview of developments in the field and then discusses the definition of HRQL. The different types of HRQL measure available to researchers are described, with specif...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050132
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:In the present study, we aimed to evaluate the sexual function in patients with multiple sclerosis (MS) who were examined in two subgroups and compare the results to the control group with a validated questionnaire. METHODS:A total of 23 consecutive female MS patients divided into groups with relapsing-remitti...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0891-4
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Previous studies reported improved outcomes for bladder cancer patients who had radical cystectomy (RC) performed by surgeons and hospitals with high annual RC volumes. The objective of this study was to determine the effect of high hospital and surgeon volume on overall survival after RC fo...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1457-4
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Assess knowledge and awareness concerning human papillomavirus (HPV) infection, HPV-associated diseases, and the existence of a specific vaccine among non-HPV-screened Caucasian-European adults after the market introduction of HPV vaccines. METHODS:A cohort of 934 consecutive patients seeking their first medic...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1379-1
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Prognoses for intermediate-risk prostate cancer (PCa) remain heterogeneous. Improved substratification could optimize treatment and monitoring strategies. The objective was to validate this subclassification in a radical prostatectomy (RP) series. METHODS:Between 2000 and 2011, 4038 patients who underwent R...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-016-1979-z
更新日期:2017-08-01 00:00:00
abstract::Robotic surgery was started in the Department of Urology, Hospital Kuala Lumpur, in April 2004. We present our experience in developing the program and report the results of our first 50 cases of robotic radical prostatectomy. A three-arm da Vinci robotic system was installed in our hospital in March 2004. Prior to in...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-006-0069-z
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:For better understanding of urogenital tuberculosis (UGTB), its clinical spectrum and characteristic features need to be evaluated. MATERIALS AND METHODS:One hundred and forty-two cases of UGTB patients were analyzed retrospectively. We considered age, gender, symptoms, and diagnostic procedures. RESULTS:The ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02767-x
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:We sought to examine the literature reporting the effect of urinary tract infection (UTI) on non-schistosomiasis-related UBC (UBCNS) through a systematic review and meta-analysis. METHODS:A predefined study protocol was developed according to PRISMA. Medline and Scopus were searched for all studies investigati...
journal_title:World journal of urology
pub_type: 杂志文章,meta分析
doi:10.1007/s00345-018-2257-z
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:Management of prostate cancer following radiation therapy remains challenging, especially for younger men or those with life expectancy greater than 10 years. We outline the efficacy, safety and adequacy of radical prostatectomy for the treatment of radiorecurrent localized prostate cancer. METHODS:A systemati...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-013-1029-z
更新日期:2013-12-01 00:00:00
abstract::Urinary bladder cancer (UBC) is a common disease worldwide. At any point in time 2.7 million people have a history of UBC. The incidence of UBC varies over the world with highest rates in developed communities. But the burden of UBC will increase in less developed areas of the world. These changes can be attributed to...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-009-0383-3
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:To compare the range of reach of our newly designed omni-directional ureteroscope (URF-Y0016), compared to the commonly used URF-P6, FlexX2s, and LithoVue™ scopes, in the upper, middle, and lower calyces in an ex-vivo pyelocaliceal model. METHODS:We fabricated a three-dimensional pyelocaliceal model of the upp...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03151-w
更新日期:2020-03-14 00:00:00
abstract:OBJECTIVES:It has been reported that apoptosis of penile erectile tissue occurs after penile denervation, castration, and diabetes mellitus in animal studies. Aim of this study was to investigate apoptosis in corpora cavernosa of patients with organic erectile dysfunction (ED). METHODS:Cavernous biopsies were obtained...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0332-6
更新日期:2009-04-01 00:00:00