Abstract：
BACKGROUND:Evidence suggests that both selenium and vitamin E reduce the risk of prostate cancer. The Selenium and Vitamin E Cancer Prevention Trial (SELECT) is a randomized, prospective, double-blind study designed to determine whether selenium and vitamin E alone and in combination can reduce the risk of prostate cancer among healthy men. MATERIALS AND METHODS:The preclinical and epidemiological evidence supporting a role for selenium and vitamin E as chemopreventive agents in prostate cancer are reviewed, and details of the trial design are presented. RESULTS. Preclinical, epidemiological, and phase III data from randomized, placebo-controlled clinical trials suggest that both selenium and vitamin E have potential efficacy in prostate cancer prevention. SELECT is a 2x2 factorial study with an accrual goal of 32,400 men with nonsuspicious DRE and serum PSA of 4 ng/ml or lower. CONCLUSIONS:SELECT is the second large-scale study of chemoprevention for prostate cancer. Enrollment began in 2001 with final results anticipated in 2013.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Klein EA,Lippman SM,Thompson IM,Goodman PJ,Albanes D,Taylor PR,Coltman Cdoi
10.1007/s00345-002-0314-zkeywords:
subject
Has Abstractpub_date
2003-05-01 00:00:00pages
21-7issue
1eissn
0724-4983issn
1433-8726journal_volume
21pub_type
杂志文章,评审abstract：INTRODUCTION AND OBJECTIVES:Reactive oxygen species (ROS) are produced during the interaction between oxalate/calcium oxalate monohydrate (COM) crystals and renal epithelial cells and are responsible for the various cellular responses through the activation of NADPH oxidase (Nox). Ox and COM also activate the renin-ang...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1563-y
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:Vesico-ureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Surgery is an important part of its management. Laparoscopic ureteric reimplantation using the Lich-Gregoir technique is an option for VUR. The aim of this study is to assess short- and medium-...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2064-y
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To critically review and synthesize data of ureteroscopy (URS) in different circumstances that all urologists may encounter during everyday clinical practice, such as pregnancy, obesity, bleeding diathesis, renal stones larger than 2 cm, calyceal diverticula, and kidney malformations. METHODS:According to PRIS...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-014-1345-y
更新日期：2015-02-01 00:00:00
abstract：:Candiduria is commonly seen in hospitalized patients and most of the patients are asymptomatic, but it may be due to cystitis, pyelonephritis, prostatitis, epididymo-orchitis or disseminated candidiasis. Major risk factors are diabetes mellitus, indwelling urinary catheters, use of broad-spectrum antibiotics, urinary ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02991-5
更新日期：2020-11-01 00:00:00
abstract：:We prospectively compared, within the same center and during the same period of time, the perioperative parameters as well as the oncological and functional results of both open retropubic (ORP) and laparoscopic radical prostatectomy (LRP). From September 1999 to September 2001, 162 patients with prostate cancer were ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-002-0306-z
更新日期：2003-05-01 00:00:00
abstract：:Reconstruction of long anterior urethral strictures that cannot be excised and reanastomosed remains controversial. We critically reviewed the literature on free-graft and pedicled skin-flap urethroplasty to determine the optimal method of repair. Overall, free grafts were successful in 84.3% of cases and flaps, in 85...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050048
更新日期：1998-01-01 00:00:00
abstract：:The aim of this cross-sectional study was to compare single with repeated high-intensity focused ultrasound (HIFU) treatment in patients with localized prostate cancer, regarding treatment-related morbidity. A number of 223 consecutive patients with localized prostate cancer were treated with HIFU. Among them, 174 (78...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-006-0107-x
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of WX-G250, a chimeric monoclonal antibody that binds to carboxy anhydrase IX, combined with low-dose interferon-alpha (LD-IFNα) in patients with progressive metastatic renal cell carcinoma (mRCC). PATIENTS AND METHODS:Thirty-one patients, nephrectomized for the primary tumo...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-010-0570-2
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:A paucity of data exists on the insignificant disease potentially suitable for active surveillance (AS) among men with intermediate-risk prostate cancer (PCa). We tried to identify pathologically insignificant disease and its preoperative predictors in men who underwent radical prostatectomy (RP) for intermedia...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1413-3
更新日期：2014-12-01 00:00:00
abstract：:Recent investigations have given a clearer insight into the genetic progression of bladder cancer. In this review we identify the clinical courses of bladder cancer, review the basic concepts of carcinogenesis, and focus on the specific cytogenetic and molecular alterations observed in bladder cancer. Progression mode...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00184243
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:This report presents our early experience at Cleveland Clinic replacing conventional ultrasound with a novel 29 MHz high-resolution micro-ultrasound system for both systematic sampling and real-time targeting of suspicious regions during prostate biopsy. The added value of micro-ultrasound and MRI over systemat...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02863-y
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To assess the performance of EAU risk classification in PCa patients according to the biopsy pathway (standard versus MRI guided) and to develop a new, more accurate, targeted biopsy (TB)-based classification. MATERIALS AND METHODS:We included 1345 patients consecutively operated by radical prostatectomy (RP) ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-03053-6
更新日期：2020-10-01 00:00:00
abstract：:The surgical complications encountered in 478 patients who underwent primary retroperitoneal lymph-node dissection for clinical stage A and B nonseminomatous testicular cancer during the period ranging from 1982 to 1992 were reviewed. There were 54 complications in 51 patients (10.6%), and there was no surgery-related...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00192272
更新日期：1994-01-01 00:00:00
abstract：:Our objectives were to ascertain the tolerability and efficacy of trospium chloride in doses of 20 mg twice daily for long-term therapy (52 weeks) in patients with urge syndrome. The trial comprised a total of 358 patients with urge syndrome or urge incontinence. After randomisation in the ratio of 3:1, participants w...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/s00345-003-0321-8
更新日期：2003-05-01 00:00:00
abstract：PURPOSE:Robotic radical cystectomy (RRC) has become a commonly utilised alternative to open radical cystectomy (ORC). We performed a systematic review and meta-analysis of RRC vs ORC focusing on perioperative outcomes and safety. METHODS:Medline, EMBASE and CENTRAL were searched from January 2000 to April 2020 followi...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-020-03385-8
更新日期：2020-07-30 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:The possibility of performing remote-surgery has been the goal to achieve, since the early development of the first surgical robotic platforms. This systematic review aims to analyse the state of the art in the field and to provide an overview of the possible growth of this technology. METH...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02996-0
更新日期：2020-10-01 00:00:00
abstract：:The author presents the life and achievements of Johann von Mikulicz-Radecki and his contribution to European and world surgery. Mikulicz was born in Czernowitz, then a part of the Austro-Hungarian Empire. He was educated in numerous Austrian schools and graduated at Vienna University in 1875. In 1880 he became surgeo...
journal_title：World journal of urology
pub_type： 传,历史文章
doi：10.1007/s00345-007-0227-y
更新日期：2008-02-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:Previous studies reported improved outcomes for bladder cancer patients who had radical cystectomy (RC) performed by surgeons and hospitals with high annual RC volumes. The objective of this study was to determine the effect of high hospital and surgeon volume on overall survival after RC fo...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1457-4
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To examine the effect of marital status and gender on stage at diagnosis, tumor grade, treatment type and cancer specific mortality (CSM) in patients with localized renal cell carcinoma (RCC). METHODS:Within Surveillance, Epidemiology, and End Results registry (2001-2013), we identified 57,700 patients with T1...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2082-9
更新日期：2017-12-01 00:00:00
abstract：:The aim of this study was to determine and compare the effects of both magnesium citrate and phytin on reducing urinary calcium excretion under high-calcium-diet conditions during single and combined treatments. An animal experiment was carried out over a period of 4 weeks in 35 male rats. Urinary calcium excretion wa...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00184113
更新日期：1994-01-01 00:00:00
abstract：:Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. The current indications for the surgical correction of VUR depend on the presence or absence of renal scars. If no scars are present, primary ureteral reimplantation is only indicated in high-grade bil...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0408-x
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To provide most recent and high quality evidence concerning the comparison between monopolar and bipolar transurethral resection of non-muscle invasive bladder tumors. MATERIALS AND METHODS:Two researchers performed a systematic review of the current literature independently, to identify studies published in...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03313-w
更新日期：2020-06-26 00:00:00
abstract：PURPOSE:To assess whether real-time elastography-targeted biopsy (RTE-bx) is superior to the standard systematic transrectal ultrasound (TRUS)-guided biopsy in predicting subsequent prostate cancer (PCa) rates in patients with initially negative biopsy and to specifically reveal differences in the occurrence of high-gr...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2178-x
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Lymph node dissection (LND) is not routinely performed during radical nephroureterectomy (RNU) in upper tract urothelial carcinomas (UTUC), and its clinical relevance is unclear. The purpose of the present study was to evaluate the impact of LND on clinical outcomes in a large multicenter series of RNU for UTUC...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-011-0705-0
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Muscle-invasive bladder cancer (MIBC) is an aggressive disease for which treatment strategies are continuously evolving. We characterized trends in treatment modalities for MIBC from 2004 to 2013 (the "pre-immunotherapy era") and identified predictors of receiving the current standard of care treatment: ne...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2371-y
更新日期：2018-11-01 00:00:00
abstract：PURPOSE:To assess the long-term patient-reported outcomes following TO-TVT as a secondary continence procedure in women with recurrent stress urinary incontinence (R-SUI). METHODS:A secondary analysis of the 9-year follow-up of the E-TOT study was performed: 341 women with predominant SUI symptoms were randomised to u...
journal_title：World journal of urology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00345-016-1969-1
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:To evaluate the role of multiparametric magnetic resonance imaging (mpMRI) in Gleason score (GS) 3 + 4 prostate cancer (PCa) and evaluate independent factors in mpMRI that can predict GS upgrading, we compared the outcomes of GS upgrading group and GS non-upgrading group. PATIENTS AND METHODS:We analyzed th...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03421-7
更新日期：2020-08-31 00:00:00
abstract：PURPOSE:To evaluate the role of adrenergic and nitrergic signaling on ureteric peristaltic frequency and contraction force in vivo using a large animal model. METHODS:Twelve female pigs (72 ± 4 kg) were chronically instrumented with an electronic pressure-monitoring catheter in the right ureter. Nephrostomy, cystostom...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1663-8
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To review the recent advances in terms of surgical technique and new robotic platforms applied to radical perineal prostatectomy (RPP). METHODS:A literature review was performed focusing on original articles on perineal prostatectomy searching via Medline/Pubmed and Embase. The entire spectrum was covered such...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-03004-1
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:Despite the increasing number of studies confirming the importance of neoadjuvant chemotherapy (NC) in patients before radical cystectomy (RC) for bladder cancer (BCa), NC remains underused. The aim of our study was to develop a nomogram predicting the cancer-specific mortality (CSM) of patients who underwent R...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-015-1640-2
更新日期：2016-02-01 00:00:00
