当前位置： SCI文献检索 > WORLD JOURNAL OF UROLOGY期刊下所有文献 > Development and validation of nomograms to predict the recovery of urinary continence after radical prostatectomy: comparisons between immediate, early, and late continence.

Development and validation of nomograms to predict the recovery of urinary continence after radical prostatectomy: comparisons between immediate, early, and late continence.

Abstract：

PURPOSE:Few studies have been conducted on the serial evaluation of predictors for recovery of urinary continence (RC) after radical prostatectomy (RP) among same cohort. We developed and validated nomograms to predict immediate (≤1), early (≤3), and late (≤12 months) RC from a contemporary series and compared each nomogram with regard to the significance of predictors for RC. METHODS:Among consecutive men who received robot-assisted or open retropubic RP between 2004 and 2011, 872 (74.7 %) and 296 (25.3 %) were randomly assigned to subcohorts for the development of nomograms and for the split-sample external validation. The final multivariate model was selected based on the stepwise procedure, and the regression coefficient-based nomograms were developed based on final models. RESULTS:Age at surgery, membranous urethral length (MUL), and robot-assisted RP were significant for RC at 1, 3, and 12 months. Saving the neurovascular bundle (NVB) and prostate volume were significant only for RC at 12 months. Odds ratios for age and MUL were constant over time, whereas the odds ratio for robot-assisted surgery decreased over time. Each developed nomogram was reasonably well fitted to the ideal line of the calibration plot. The split-sample external validation of nomograms indicated 63, 65, 71 % accuracy for each RC time point. CONCLUSIONS:We developed nomograms for RC at each time point after RP and validated adequately. Saving the NVB and prostate volume may affect only late RC after RP. In contrast, age, MUL, and robot-assisted surgery seem to be consistently associated with immediate, early, and late RC.

journal_name

World J Urol

journal_title

World journal of urology

authors

Jeong SJ,Yeon JS,Lee JK,Cha WH,Jeong JW,Lee BK,Lee SC,Jeong CW,Kim JH,Hong SK,Byun SS,Lee SE

doi

10.1007/s00345-013-1127-y

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

437-44

issue

2

eissn

0724-4983

issn

1433-8726

journal_volume

32

pub_type

杂志文章

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