The SACD method and the XLRS squamometry tests revisited.

Abstract:

:The assessment of many aspects of the structure and biological dynamics of the stratum corneum can be conducted using calibrated stripping with adhesive-coated discs (SACD). Squamometry entails staining SACD samples with a toluidine blue-basic fuschsin ethanol-based solution and reading the colorimetric variable Chroma C* representing the squamometry index. Four main variants of squamometry index have been designed so far. Squamometry X refers to the assessment of xerosis and any scaly condition. Squamometry L explores the intercorneocyte cohesiveness impaired by ultraviolet light. Squamometry R evaluates stratum corneum renewal and squamometry S assesses the effect of surfactants on corneocyte integrity. This latter variant is related to, although not similar to, the ex-vivo corneosurfametry bioassay. All squamometry tests are rapid, reliable, sensitive and cheap.

journal_name

Int J Cosmet Sci

authors

Piérard-Franchimont C,Henry F,Piérard GE

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

437-46

issue

6

eissn

0142-5463

issn

1468-2494

pii

ICS039

journal_volume

22

pub_type

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