Abstract:
:The causative substances for axillary osmidrosis, which are often found in apocrine sweat, are the decomposed/denatured products of short-chain fatty acid and other biological metabolite compounds produced by axillary-resident bacteria. Conventional underarm deodorants suppress the process of odour production mostly by the following mechanism: (1) suppression of perspiration, (2) reduction in numbers of resident bacteria, (3) deodorization and (4) masking. The most important and effective method to reduce odour is to suppress the growth of resident bacteria with antimicrobials, which have several drawbacks, especially in their safety aspect. To solve these problems, we focused on Ag-zeolite (silver-exchanged zeolite) that hold stable Ag, an inorganic bactericidal agent, in its structure, and therefore, poses less risk in safety. Its bactericidal effect on skin-resident bacteria was found to be excellent and comparable with that of triclosan, a most frequently used organic antimicrobial in this product category. The dose-response study of Ag-zeolite powder spray (0-40 w/w%) using 39 volunteers revealed that 5-40 w/w% Ag-zeolite could show a sufficient antimicrobial effect against skin-resident bacteria. The comparison study using 0.2 w/w% triclosan as the control and 10 w/w% Ag-zeolite indicated that: (1) one application of the powder spray containing 10 w/w% Ag-zeolite could show a sufficient antimicrobial effect against the resident bacteria and its effect continued for 24 h, (2) a powder spray containing 0.2 w/w% triclosan was unable to show a sufficient antimicrobial effect, and (3) no adverse event was observed. These studies show that Ag-zeolite has a superior antimicrobial ability that is rarely found in conventional antimicrobials used in deodorant products and a strong antiaxillary odour deodorant ability because of its long-lasting effect. During clinical study, patch tests with humans and other clinical studies of this product showed no adverse events related to the treatment with the Ag-zeolite product.
journal_name
Int J Cosmet Scijournal_title
International journal of cosmetic scienceauthors
Nakane T,Gomyo H,Sasaki I,Kimoto Y,Hanzawa N,Teshima Y,Namba Tdoi
10.1111/j.1467-2494.2006.00322.xsubject
Has Abstractpub_date
2006-08-01 00:00:00pages
299-309issue
4eissn
0142-5463issn
1468-2494pii
ICS322journal_volume
28pub_type
杂志文章abstract:BACKGROUND:Mechanical analysis of human hair may provide the dermatologists with several markers of considerable diagnostic importance. The aim of this study was to analyse the physical and mechanical properties of Tunisian women's hair. METHODS:Surface characteristics were determined with scanning electron microscopy...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12313
更新日期:2016-10-01 00:00:00
abstract::A multicentred study derived from the COLIPA in vitro UVA method was performed to assess the influence of test conditions on UVA protection factor (UVAPF) values in terms of amplitude, reproducibility between laboratories and correlation with in vivo UVA results. Eight products with a range of in vivo UVAPF from three...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1468-2494.2012.00748.x
更新日期:2013-02-01 00:00:00
abstract::Synopsis An O/W/O multiple emulsion was formulated using almond oil as the inner phase and liquid paraffin as the outer phase. The properties of the formulation ingredients were explored: effect of the type of primary emulsifier, and the nature and concentration of the secondary emulsifier. The volume fraction of the ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1994.tb00077.x
更新日期:1994-02-01 00:00:00
abstract::Synopsis The ability of baseline transepidermal water loss (TEWL) measurements to predict the response of healthy subjects to a standard soap chamber irritation insult was evaluated. Chambers containing surfactant solutions were applied to the forearms of normal volunteers for five consecutive days. TEWL was measured ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1986.tb00452.x
更新日期:1986-10-01 00:00:00
abstract:OBJECTIVE:Vitamin C and peptides are widely used in cosmetic products but there is a paucity of clinical studies showing that the formulations are effective in treating signs of facial ageing. These 3 clinical studies evaluated the effectiveness of an anti-ageing formula containing natural vitamin C (10%), biopeptides ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12665
更新日期:2020-10-10 00:00:00
abstract::Cutaneous ageing is the result of two distinct, biological processes which may occur concurrently: (i) the passage of time, termed intrinsic ageing and (ii) environmental influences, termed extrinsic ageing. Intrinsic ageing of the skin is a slow process which causes changes in tissue structure and impairs function in...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,评审
doi:10.1111/j.1468-2494.2010.00574.x
更新日期:2010-10-01 00:00:00
abstract::This work describes the development, validation and application of a simple and fast high-performance liquid chromatography-with diode array dectection (HPLC-DAD) method for the determination of eight sunscreen agents: benzophenone-3, octocrylene, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate (used in...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2012.00703.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:Ageing leads to characteristic changes in the appearance of facial skin. Among these changes, we can distinguish the skin topographic cues (skin sagging and wrinkles), the dark spots and the dark circles around the eyes. Although skin changes are similar in Caucasian and Chinese faces, the age of occurrence ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12128
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:Hyaluronan (HA) plays a role in keratinocyte proliferation and differentiation. In addition, HA has been shown to have different biological activities depending on its molecular weight. It has been reported that HA-mediated CD44 activation regulates keratinocyte differentiation. Therefore, the aim of this stu...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12105
更新日期:2014-02-01 00:00:00
abstract::Synopsis This study has evaluated the ultraviolet light transmission characteristics of human stratum corneum at the single cell level using a low light level video microscope to measure the mean percentage transmission of light at different wavelengths and the variation in transmission across the stratum corneum. Str...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1989.tb00508.x
更新日期:1989-08-01 00:00:00
abstract::Synopsis In the last few years a lot of attention has been paid to the development of the in vitro models which would substitute for animals in cutaneous irritancy studies. These models explore either organ or explant cultures using freshly excised skin or serial cultures of isolated skin cells (epidermal keratinocyte...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1992.tb00058.x
更新日期:1992-12-01 00:00:00
abstract:OBJECTIVE:The objective of this work was to investigate the utility of a new in vitro SPF test method in blinded ring-testing, against new ISO acceptance criteria. METHODS:Twenty four blinded, commercial, emulsion-type, primary sunscreen products, covering the full range of labelled SPF in Europe (SPF6 - 50+), were te...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12459
更新日期:2018-04-20 00:00:00
abstract::Synopsis Glutathione (GSH) plays an important role in cellular protection during ageing. The hair plucking technique is a non-invasive method for the direct biochemical study of keratinocytes. Hair was taken from the suboccipital area of 63 volunteers (men and women whose ages ranged from 13 to 103 years). The results...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1991.tb00555.x
更新日期:1991-06-01 00:00:00
abstract::Synopsis The aim of this work was to evaluate several plant extracts with regard to ultraviolet absorption spectra in view of a possible application as antisolar agents. Liquid and dry extracts of Hamamelis virginiana, Matricaria recutita, Aesculus hippocastanum, Rhamnus purshiana and Cinnamomum zeylanicum were prepar...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1996.tb00140.x
更新日期:1996-06-01 00:00:00
abstract::Synopsis An historical reference is followed by a review of cosmetic colours' regulations based on the EEC Directive with particular reference to the U.K. Cosmetic Products Regulations and their effect on formulation. ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1979.tb00217.x
更新日期:1979-08-01 00:00:00
abstract::Synopsis The mechanism of colour change during the pigment dispersion process and during powder application to the skin surface was studied by examining the colour extension properties of Yellow. Red, and Black iron oxides in white powder bases. A new measure for the evaluation of the degree of colour extension was de...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1985.tb00391.x
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:Although the olfactory receptor OR2AT4 was described as involved in epidermal renewal, there is no data about a cosmetic active ingredient activating this receptor. The aim of this research work was thus to identify a natural molecule binding to this receptor in order to stimulate keratinocyte migration. MET...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12526
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To investigate the efficacy of 13 antimicrobial substances (11 substances of natural origin and two conventional preservatives as controls) at two concentrations in an o/w cosmetic emulsion. METHODS:Cosmetic formulations were analysed for total aerobic bacterial count and total combined yeast count according...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12461
更新日期:2018-05-05 00:00:00
abstract::In the present contribution, the properties of dipropylene glycol isobornyl ether (Pribelance) are discussed, especially in the context of microemulsion and emulsion formulations. Pribelance is a new low-toxic anti-foaming hydrotrope with excellent co-surfactant properties that has some similarities with long-chain al...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2008.00460.x
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (Ananas comosus) and other species of Bromeliaceae. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical and cosmetic industries, for its cell renewal, anti-ageing, whiteni...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12308
更新日期:2016-10-01 00:00:00
abstract::The assessment of many aspects of the structure and biological dynamics of the stratum corneum can be conducted using calibrated stripping with adhesive-coated discs (SACD). Squamometry entails staining SACD samples with a toluidine blue-basic fuschsin ethanol-based solution and reading the colorimetric variable Chrom...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Summary Nowadays, cosmetic as well as pharmaceutical forms must undergo many controls, i.e. in-process controls on the finished product and stability testing. The authors suggest using first derivative spectroscopy for active ingredients assay presenting an ultra-violet absorption. It offers the advantage of a direct ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1467-2494.1994.tb00087.x
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:To demonstrate the in vitro activities of panthenol, palmitoylethanolamide (PEA), and niacinamide (NAM) and determine the biophysical properties, clinical safety, tolerability together with efficacy of two developmental anti-redness (AR) formulations containing these ingredients, in alleviating facial redness...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12559
更新日期:2019-12-01 00:00:00
abstract::Many studies have presented stress-strain relationship of human hair, but most of them have been based on an engineering stress-strain curve, which is not a true representation of stress-strain behaviour. In this study, a more accurate 'true' stress-strain curve of human hair was determined by applying optical techniq...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12031
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Xerosis is an abnormally dry and flaky skin condition that is associated with a change in the packing behaviour of the lipid matrix in the stratum corneum (SC), the outermost layer of the skin. This skin condition can lead to an increase in transepidermal water loss (TEWL). As ultralong-chain fatty acids hav...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12404
更新日期:2017-10-01 00:00:00
abstract::The hydroglycolic (HG) extract from 70% propylene glycol (PG) extraction of myrobalan fruits showed the most appreciable antioxidant efficiency towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) in comparison to the extracts from 30, 50, 70 and 100% ethyl alcohol (EA), and 30, 50 and 100% PG . Its total polyphenols were als...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/j.1468-2494.2011.00642.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Several studies have shown that a deterioration of skin properties, an impaired cutaneous microcirculatory function and an imbalance of autonomic nervous activity are observed in smokers and in patients with diabetes mellitus or Raynaud's phenomenon. These observations suggest that skin properties are associa...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1111/ics.12373
更新日期:2017-06-01 00:00:00
abstract::Sweat and skin surface pH are critical parameters in determining the performance of antiperspirants. The mechanism of action, the so-called 'plug theory' first proposed by Reller and Luedders, involves the expression of eccrine sweat onto the surface of the skin into which the solid antiperspirant salts, typically an ...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.2001.00092.x
更新日期:2001-08-01 00:00:00
abstract::Lysyl oxidase-like (LOXL) is an extracellular enzyme that catalyses the cross-linking between microfibrils and tropoelastin (TE), thereby ensuring elastic fibre functionality. With ageing, LOXL expression decreases, thus participating in the loss of skin elasticity. In a previous study, we showed that a dill seed extr...
journal_title:International journal of cosmetic science
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1468-2494.2010.00606.x
更新日期:2011-04-01 00:00:00
abstract::The photostabilities of four sunscreen products have been assessed in vitro by applying sunscreen to a substrate and measuring the spectral transmission prior to, and after exposure to a source of ultraviolet (UV) radiation. Results were independent of whether an application thickness of 1 or 2 mg/cm ; 2 was used, and...
journal_title:International journal of cosmetic science
pub_type: 杂志文章
doi:10.1046/j.1467-2494.1999.203163.x
更新日期:1999-10-01 00:00:00