Chemotherapy as a therapeutic option for congenital neuroblastoma complicated by paraplegia.

Abstract:

BACKGROUND:Spinal compression can be a complication of neuroblastoma (NBL). Delayed or insufficient treatment of this condition may lead to permanent neurological sequelae. Therefore, appropriate treatment should be introduced promptly. Therapeutic options include neurosurgery, chemotherapy, and radiation therapy. CASE REPORT:We report on a newborn male with congenital NBL who presented with complete paraplegia of the legs at birth. Tumor size diminished quickly and neurological symptoms partly recovered after the patient received chemotherapy consisting of vincristine, doxorubicine, and cyclophosphamide. CONCLUSION:Rapid initiation of chemotherapy was safe and effective in a neonate with NBL complicated by spinal cord compression.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Walter KN,Kratz C,Uhl M,Niemeyer C

doi

10.1055/s-2008-1065340

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

175-7

issue

3

eissn

0300-8630

issn

1439-3824

journal_volume

220

pub_type

杂志文章
  • [The diagnostic value of cytology of the CSF (author's transl)].

    abstract::Cytological examination of cerebrospinal fluid needs special techniques of cell collecting and staining. On condition of realizing the methodical requirements cytology of the cerebrospinal fluid brings more advancement in diagnostics than other laboratory examinations. The advantages of this procedure are: 1. Meningit...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Harms D

    更新日期:1975-03-01 00:00:00

  • [Severe 46,XY virilization deficit due to 17beta-hydroxysteroid dehydrogenase deficiency].

    abstract:BACKGROUND:17beta hydroxysteroid dehydrogenase deficiency is a presumable rare cause for a severe virilization disorder in children with 46,XY karyotype due to a defect in the testicular testosterone biosynthesis from androstenedione. PATIENT:We report on a 14 year old child with 46,XY karyotype with a predominantly f...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2002-34015

    authors: Twesten W,Johannisson R,Holterhus PM,Hiort O

    更新日期:2002-09-01 00:00:00

  • [Concordance of prune belly syndrome and VACTERL association].

    abstract::We report on a male premature infant with hypoplastic abdominal wall musculature, urinary tract anomalies and kryptorchism--the main features of Prune-Belly-syndrome. Furthermore the patient showed cardiac anomalies, urinary tract anomalies, limb defects, vertebral anomalies and anal atresia, which belong to the main ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Oztürk B,Weber HP,Ganz A

    更新日期:1994-09-01 00:00:00

  • [Recurrent subacute endocarditis caused by Streptococcus mutans in a child].

    abstract::Bacterial endocarditis belongs to the rare diseases in childhood. It occurs usually as a single episode and almost exclusively in children with congenital heart disease. In recent years, however, an increased number of renewed endocarditis after the first episode were reported, especially in drug addicts. We present a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1046498

    authors: Hunkert F,Handrick W,Kinzel P,Schneider P,Spencker FB,Günther E

    更新日期:1995-01-01 00:00:00

  • [Predictors of follow-up course of asthma complaints in early childhood--results of a follow-up study].

    abstract::A follow-up study was undertaken to determine the predictors of the course of recurrent wheezing episodes in children (between 0 to 8 years). In 1991, 600 children with wheezing episodes had been recorded by physicians who participated in a sentinel practice network. On each consultation with the same physicians from ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043843

    authors: Seidler A,Schlaud M,Raum E,Schwartz FW

    更新日期:1998-01-01 00:00:00

  • [Delay of constitutional development--studies on therapy with growth hormone].

    abstract::Human growth hormone was given to 6 boys with constitutional delay of growth and development. Three patients had normal growth hormone responses following exercise or insulin-induced hypoglycemia. Subnormal growth rate (less than 2 SD below normal for bone age) was found in 4 patients. The mean growth rate of the pati...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-1025580

    authors: Butenandt O

    更新日期:1984-03-01 00:00:00

  • [Peritonitis and infection in children with idiopathic nephrotic syndrome].

    abstract::We analyzed episodes of peritonitis and/or sepsis associated with the idiopathic nephrotic syndrome (ns) in 23 children treated between 1975 and 1985 at our clinic. 37.5% of the children with infantile ns, 16% of those with steroidsensible ns, and 13.6% of those with steroidresistant ns developed peritonitis. Children...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033683

    authors: Feldhoff C,Kleine L,Bachmann H

    更新日期:1988-01-01 00:00:00

  • Extending the Concept of Advance Care Planning to the Perinatal Period.

    abstract::Easier access to prenatal diagnostic procedures led to its widespread use as a screening measure. Hence, today it is more common for life-limiting illnesses to be diagnosed during fetal life. The concept of Advance Care Planning (ACP) provides a framework for caregivers, families and their multidisciplinary teams to a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/a-1179-0530

    authors: Garten L,von der Hude K,Strahleck T,Krones T

    更新日期:2020-09-01 00:00:00

  • [Non-immunologic hydrops fetalis--report of 14 cases and literature review].

    abstract::With the advent of prenatal diagnosis and the feasibility of intrauterine treatment, non-immune hydrops fetalis (NHIF) is gaining increasing importance. 14 patients are reported 10 of whom having been diagnosed prenatally. 13 were born prematurely severe asphyxia being a frequent occurrence. 7 out of 14 infants surviv...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033984

    authors: Kühl PG,Ulmer HE,Schmidt W,Wille L

    更新日期:1985-07-01 00:00:00

  • [Fat-emulsions and acid-base balance in neonates of low weight at birth (author's transl)].

    abstract::The influence of a single intravenous infusion of triglycerides (1 g triglyceride per kg body weight) on the acid base equilibrium was investigated in 16 newborn infants with low birth weight during the first days of age. No changes of pH, PCO2 and standard bicarbonate, base excess, buffer base and actuelle bicarbonat...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Melichar V,Wolf H,Jirsová V,Vondrácek J

    更新日期:1975-09-01 00:00:00

  • [Comparison of chemotherapy alone with allogeneic bone marrow transplantation in first full remission in children with acute myeloid leukemia in the AML-BFM-83 and AML-BFM-87 studies--matched pair analysis].

    abstract::16 patients of studies AML-BFM-83 and -87 with allogeneic bone marrow transplantation (BMT) in first complete remission (CR) were compared with matched controls with postremission chemotherapy (CT-MC). CT-MC were selected from 250 non-grafted patients with a minimum of remission duration corresponding to the median in...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2007-1025355

    authors: Creutzig U,Bender-Götze C,Klingebiel T,Ebell W,Friedrich W,Stollmann-Gibbels B,Schmidt H,Suttorp M,Gratwohl A,Heyen P

    更新日期:1992-07-01 00:00:00

  • [Changes on platelet adhesion, aggregation and production in course of mumps and mumps meningitis (author's transl)].

    abstract::In 20 children with mumps and mumps meningitis thrombocyte functions, the thrombopoiesis and the platelet count were examinated over a four week period. The spontaneous, standardized platelet adhesion and aggregation on silikonized glass surface showed a statistically significant increase from the 5th to the 15th day ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Lemanczyk S,Podolsak B

    更新日期:1977-09-01 00:00:00

  • [Hearing screening of newborn infants at risk for perinatal hearing damage].

    abstract::630 neonates with risk factors of perinatal hearing impairment were screened of hearing loss by means of registration of transient otoacoustic emissions before discharge from the newborn nursery. Neonates were screened additionally by means of brainstem evoked response audiometry, if they had bilateral negative emissi...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043853

    authors: Sitka U,Rehm K,Rasinski C

    更新日期:1998-03-01 00:00:00

  • Children and adolescents with fetal alcohol syndrome (FAS): better social and emotional integration after early diagnosis.

    abstract:BACKGROUND:Alcoholism during pregnancy is one of the most common factors in western societies causing persisting congenital and multiple physical as well as neurological impairments. Finding the diagnosis at first sight puts medical professionals into a demanding situation. Therefore the objective of this study was to ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1299682

    authors: Alex K,Feldmann R

    更新日期:2012-03-01 00:00:00

  • [Determination and clinical significance of colloid osmotic pressure in pediatric patients].

    abstract::The clinical significance of colloid osmotic pressure (COP) in transcapillary fluid exchange and water homeostasis in health and disease is described. Under pathophysiological circumstances measurement of COP should be preferred to COP value calculation. After extensive COP experiences in critically ill adults and num...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034010

    authors: Abel M

    更新日期:1985-09-01 00:00:00

  • [Measles epidemic in a highly developed country: low mortality, high morbidity and extensive costs].

    abstract:BACKGROUND:Vaccination with 2 doses of > 95% of the population is necessary to eliminate measles. In Switzerland and especially in the central part, vaccine coverage is low (2006: 65%). This led 2006-2009 to a measles epidemic with thousands of cases and high costs. One death was noted in a formerly healthy 12 year old...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0033-1363254

    authors: Donas A,Marty-Nussbaumer A,Roost HP,Neuhaus TJ

    更新日期:2014-01-01 00:00:00

  • [Retrospective marker analyses performed with blood and bone marrow smears using an immunoenzyme procedure (alkaline phosphatase-anti-alkaline phosphatase technic)].

    abstract::In the present study the possibility of immunophenotyping of routinely prepared (air dried) peripheral blood and bone marrow smears is described after storage. The immunoenzymatical alkaline-phosphatase-anti-alkaline-phosphatase (APAAP)-method was carried out in differently stored blood smears (+4 degrees C and -80 de...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025311

    authors: Ebener U,Hauser S,Wehner S,Kornhuber B

    更新日期:1989-07-01 00:00:00

  • [Treatment of hepatitis B virus-associated membranous glomerulonephritis with interferon alfa in a 7 year old boy].

    abstract:BACKGROUND:The association between Hepatitis B virus infection and membranous nephropathy has been confirmed by sources in several countries. Most commonly, the illness is seen as a nephrotic syndrome. Optimal treatment remains undefined. Antiviral therapies observed with recombinant human interferon alpha may be the b...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2000-9689

    authors: Steiss JO,Piske-Keyser K,Gröne HJ,Gortner L

    更新日期:2000-09-01 00:00:00

  • [Changes in the granulocyte membrane in mucoviscidosis].

    abstract::Important polymorphonuclear leukocyte (PMN) functions are dependent on an intact cytoskeleton, consistent of the microtubulus and microfilament system. This can be assayed from the mobility of fluorescence labelled Concanavalin A (Con A) receptor complexes on the cell surface. Con A shows an uniform surface distributi...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034392

    authors: Rister M,Statz A,Brucke G

    更新日期:1983-09-01 00:00:00

  • [Neuropsychological and psychiatric aspects of language development disorder of a nine year old patient.(author's transl)].

    abstract::Problems of terminology, differential diagnosis, etiology and therapy of language development disorders are demonstrated by a casuistic example. Besides the importance of clinical date special attention was laid on neuropsychological diagnostic procedures and their therapeutic implications. Therapeutic interventions c...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Niebergall G,Wiesse J

    更新日期:1978-09-01 00:00:00

  • [Clinical and neuroradiological findings in gliomatosis of the brain with special reference to magnetic resonance tomography].

    abstract::We present three cases of GC, one belonging to the brainstem, and two belonging to the hemisphere type. Two cases were investigated by MRI. Tumour infiltration, while yielding only vague CT findings, was well demonstrated in MR studies where extensive hyperintense lesions were found in T2- and proton density images. I...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025450

    authors: Borgis KJ,Larsen JL,Mørk S,Brückmann H

    更新日期:1991-09-01 00:00:00

  • [Unusual course of a Guillain-Barré syndrome in connection with an RS-Virus infection in a 10 months old infant].

    abstract::Guillain Barré syndrome (GBS; Synonyma: Polyneuritis, Polyradikulitis) is an acute, inflammatory, demyelinating disease of the peripheral nerve system. Clinical hallmarks are symmetric muscle paralysis, areflexia and pronounced autonomic disturbances. Respiratory failure and cardiovascular instability are the main rea...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-971050

    authors: Erler T,Weidner B,Wetzel U,Grunske A

    更新日期:2008-03-01 00:00:00

  • [Evaluation of a Self-Help Supported Counseling Concept for Children and Adolescents with Disproportional Short Stature].

    abstract:BACKGROUND:Disproportionate short stature may impair the quality of life (QoL) of patients and their families. This study aimed to evaluate a self-help supported counseling concept to increase the QoL of the participants. METHODS:QoL data from 58 children/adolescents (8-17 years) with a diagnosis of achondroplasia was...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0035-1564106

    authors: Rohenkohl AC,Sommer R,Kahrs S,Bullinger M,Klingebiel KH,Quitmann JH

    更新日期:2016-01-01 00:00:00

  • [Potential coulometry, a new methodology for the determination of iron concentration in serum. Comparison with the bathophenanthroline method in protein-free solution (author's transl)].

    abstract::Iron concentration was determined by the aid of the ESA Ferrochem 3050 analyzer and the bathophenanthroline method with deproteinization. Both methods showed a good precision and accuracy. The investigation was carried out in 505 sera with an iron concentration between 9 and 333 micrograms/dl. The comparison of the tw...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033773

    authors: Liappis N

    更新日期:1982-01-01 00:00:00

  • [Autoimmune hemolytic anaemia in childhood. Review and report of one case (author's transl)].

    abstract::Autoimmune hemolytic anaemia (AIHA) in childhood is associated with antibodies produced by the patient himself, which coat his red cells causing their hemolysis. Although in some cases no underlying disease could be found, in the majority of children a virus etiology is apparent. There are very few reports regarding t...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Haas RJ,Pöschl U,Christ M,Schaub J,Belohradsky BH

    更新日期:1977-05-01 00:00:00

  • [Progressive combined immunity defect with ectomesodermal dysplasia (author's transl)].

    abstract::A boy with dysplastic features had to be treated for recurrent diarrhoea and bronchitis since his tenth month of life. Defects in humoral and cellular immunity were found. The ecto-mesodermal abnormalities are so characteristic that in connection with the immunological changes it seems to be justified to assume a yet ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Tympner KD,Belohradsky B,Eife R,Klose PK

    更新日期:1978-11-01 00:00:00

  • [Tumor markers and endocrinologic aspects in intracranial germinoma].

    abstract::This report outlines the endocrine abnormalities associated with intracranial germinoma in childhood. The presence of special tumoral markers as alpha 1-fetoprotein and beta-HCG could be of diagnostic value and is important in respect to therapy control. However the reported case shows that despite known radiosensitiv...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033927

    authors: Andler W,Horstmann W,Distelmeier PM

    更新日期:1985-01-01 00:00:00

  • [Therapy of iodine deficiency goiter in adolescents with iodine or a combination of iodine and levothyroxine with special reference to lipid parameters].

    abstract::The are various opinions about the optimal therapy of endemic goiter in adolescents. From 106 patients (75 girls) suffering from endemic goiter 50 patients (group A) were treated with 300 micrograms iodine per day and 56 patients (group B) with 100 micrograms iodine plus 100 micrograms levothyroxine per day. Before th...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1046460

    authors: Rönnefarth G,Kauf E,Deschner F,Forberger M

    更新日期:1996-05-01 00:00:00

  • [Retrospective analysis of the clinical course of 12 children given the diagnosis essential thrombocythemia].

    abstract:BACKGROUND:Essential Thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by excessive production of platelets. The disorder is usually affecting adults and is rarely diagnosed in children. PATIENTS AND METHODS:In this retrospective study we describe 12 children aged 5-16 years in whom E...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2004-832356

    authors: Kratz CP,Abd El-Monheim A,Manke EM,Rister M,Rogge T,Niemeyer CM

    更新日期:2004-11-01 00:00:00

  • [Lumbar cisternography in the evaluation of hydrocephalus in premature infants].

    abstract::Radionuclide lumbar cisternography with 111In-DTPA was utilized as a bedside procedure to evaluate CSF dynamics and the patency of the ventricular system in 29 preterm infants with hydrocephalus. Serial images of the brain were obtained at 0, 1, 2, 6, 24 and 48 hours after instillation of the isotope in the lumbar sub...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033955

    authors: Roloff DW

    更新日期:1985-03-01 00:00:00