[Delay of constitutional development--studies on therapy with growth hormone].

Abstract:

:Human growth hormone was given to 6 boys with constitutional delay of growth and development. Three patients had normal growth hormone responses following exercise or insulin-induced hypoglycemia. Subnormal growth rate (less than 2 SD below normal for bone age) was found in 4 patients. The mean growth rate of the patients treated with 12 U hGH/m2 per week increased from 4.6 to 5.1 cm/year which is not significant. Only 2 boys responded with an increment of the growth rate of more than 1 cm/year. In an age-matched control group with the same growth variation the growth rate was 4.9 and 5.0 cm/year during the same time periods. It can not be recommended to treat patients with constitutional delay of growth and development with hGH except those with severely depressed growth rate and subnormal spontaneous growth hormone secretion during sleep.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Butenandt O

doi

10.1055/s-2007-1025580

subject

Has Abstract

pub_date

1984-03-01 00:00:00

pages

69-72

issue

2

eissn

0300-8630

issn

1439-3824

journal_volume

196

pub_type

临床试验,杂志文章
  • Painful scoliosis.

    abstract::In case of painful scoliosis, a search for etiologic factors in the vertebral spinal canal and adjacent structures should be made. MRI with Gadolinium is useful to look for various pathology in and around the spine in particular of spinal cord. CT scanning is indispensible for bony details. Thus CT and MRI are complem...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1043932

    authors: Hoeffel C,Gaucher H,Hoeffel JC,Galloy MA,Arnould V

    更新日期:1997-03-01 00:00:00

  • [Trans-Sectoral Patient Care in Pediatric Oncology: Quality Assurance by Novel Reimbursement Models for Outpatient Services].

    abstract:BACKGROUND:The medical care of pediatric cancer patients in the German health care system relies on special structures. All children and adolescents with a diagnosis of cancer receive uniform treatment within clinical studies or registers and exclusively at centers which can ensure interdisciplinary care by a multiprof...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-1158-9341

    authors: Reinke E,Jürgens H,Haier J,Froehlich B,Kontny U,Rossig C

    更新日期:2020-11-01 00:00:00

  • High reliability of scrotal ultrasonography in the management of childhood primary testicular neoplasms.

    abstract:BACKGROUND:The role for testis-sparing surgery in the treatment of primary intratesticular lesions in childhood is growing. The reliability of scrotal ultrasonograpy (US) in the management of these lesions is still controversial. PATIENTS:Between 1991 and 2007, 383 children and adolescents presented with testicular ab...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1271813

    authors: Tallen G,Hernáiz Driever P,Degenhardt P,Henze G,Riebel T

    更新日期:2011-05-01 00:00:00

  • Newly diagnosed immune thrombozytopenia--German guideline concerning initial diagnosis and therapy.

    abstract::Newly diagnosed immune thrombocytopenia occurs in 3-5/100 000 children < 14 y per year. Bleeding symptoms do not correlate with platelet count. Diagnostic approach includes history, clinical examination and analysis of blood count with blood smear by experienced hematologist. Additional investigations are only necessa...

    journal_title:Klinische Padiatrie

    pub_type: 共识发展会议,杂志文章

    doi:10.1055/s-0032-1306277

    authors: Eberl W,Dickerhoff R,Pediatric Committee of Society of Thrombosis and Hemostasis Research.

    更新日期:2012-04-01 00:00:00

  • [Therapy of iodine deficiency goiter in adolescents with iodine or a combination of iodine and levothyroxine with special reference to lipid parameters].

    abstract::The are various opinions about the optimal therapy of endemic goiter in adolescents. From 106 patients (75 girls) suffering from endemic goiter 50 patients (group A) were treated with 300 micrograms iodine per day and 56 patients (group B) with 100 micrograms iodine plus 100 micrograms levothyroxine per day. Before th...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1046460

    authors: Rönnefarth G,Kauf E,Deschner F,Forberger M

    更新日期:1996-05-01 00:00:00

  • [Intensive care in pediatrics (author's transl)].

    abstract::Centralized treatment of critically ill pediatric patients and related problems are presented. Pediatric intensive care allows to overbridge deranged or interrupted organ functions while simultaneously treating the disease causing the disturbance. Its efficiency depends on continuity of medical care. Medical and nursi...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1035616

    authors: Wille L

    更新日期:1980-09-01 00:00:00

  • [Anaerobic microflora of praepubertal children (author's transl)].

    abstract::Bacteriologic cultures of the vagina and the cervix of 38 praepubertal children, aged 3 months to 16 years (average age 9 years) from the outpatient department for infants and juveniles of the 1st Department of Obstetrics and Gynecology of the University of Vienna were obtained vaginascopically using anaerobic transpo...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033769

    authors: Gerstner G,Boschitsch E,Grünberger W,Rotter M

    更新日期:1982-01-01 00:00:00

  • [Immune granulocytopenia in children].

    abstract::Immune neutropenia in infancy comprises alloimmune neutropenia and autoimmune neutropenia. Both diseases are caused by granulocyte-specific antibodies. Patients are newborns and children, often being younger than three years. Neutropenia usually leads to recurrent mild bacterial infections. Beside the blood count and ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1026742

    authors: Bux J,Mueller-Eckhardt C

    更新日期:1989-11-01 00:00:00

  • Health related quality of life after corrective surgery for congenital heart disease.

    abstract:UNLABELLED:After corrective surgery for congenital heart defects (CHD) many patients suffer from residual defects, some with reduced cardiorespiratory capacity and possible impairment of their health related quality of life (HRQoL). The aim of our study is to evaluate, how children after surgery for CHD rate their HRQo...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1382019

    authors: Heusch A,Calaminus G,Kahl J,Schmidt K

    更新日期:2014-09-01 00:00:00

  • Chemotherapy as a therapeutic option for congenital neuroblastoma complicated by paraplegia.

    abstract:BACKGROUND:Spinal compression can be a complication of neuroblastoma (NBL). Delayed or insufficient treatment of this condition may lead to permanent neurological sequelae. Therefore, appropriate treatment should be introduced promptly. Therapeutic options include neurosurgery, chemotherapy, and radiation therapy. CAS...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1065340

    authors: Walter KN,Kratz C,Uhl M,Niemeyer C

    更新日期:2008-05-01 00:00:00

  • [Quality standards and their assurance for study centers in the competence network malignant lymphoma].

    abstract:BACKGROUND:The aim of most of the trials of the Competence Network Malignant Lymphoma is to optimize the standard treatment of lymphoma using only registered drugs in the case of medicinal therapies (quality assurance protocols). In contrast to regulatory trials, special regulations for quality assurance protocols are ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-45493

    authors: Pfistner B,Mehl C,Klöss M,Löffler M,Herrmann-Frank A,Diehl V

    更新日期:2003-11-01 00:00:00

  • [NHL-BFM 90 therapy study in treatment of malignant non-Hodgkin's lymphoma in children and adolescents. Part 3: An intermediate term analysis of the B-NHL/B-ALL].

    abstract::The aims of trial NHL-BFM 90 for patients (pts) suffering from B-cell neoplasms are to prove whether: 1. Treatment for pts with complete resection can be reduced from 3 to 2 therapy courses; 2. Results for pts of stage III with large abdominal tumors can be improved by high dose (HD) chemotherapy; 3. Survival for pts ...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1055/s-2008-1046610

    authors: Reiter A,Schrappe M,Yakisan E,Sauter S,Ebell W,Zimmermann M,Hartmann W,Kremens B,Kuhn N,Claviez A

    更新日期:1994-07-01 00:00:00

  • Toilet Phobia and Toilet Refusal In Children.

    abstract::Objective: Toilet refusal syndrome (TRS) is a common disorder in toddlers, defined by use of diapers and refusal of toilet for defecation, while toilet phobia (TP) is a rare disorder in which toilets are avoided completely. Both disorders have not been described systematically in children, yet. Therefore, the aim was ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-121607

    authors: Wagner C,Niemczyk J,von Gontard A

    更新日期:2017-01-01 00:00:00

  • [The meconium ileus equivalent in mucoviscidosis].

    abstract::Meconium ileus equivalent (MIE) complicating cystic fibrosis of the pancreas (CF) increases in frequently with increasing age of patients. In the present paper the course of 11 children and adolescents with MIE diagnosed and treated at the University Dept. of Paediatrics in Zürich during the last 15 years, i.e. 9% of ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034390

    authors: Rosenberg E,Shmerling DH

    更新日期:1983-09-01 00:00:00

  • [The portal system and hepatic artery in children with biliary atresia. 1: Ultrasound and simple duplex ultrasound parameters].

    abstract::In 37 children with extrahepatic biliary atresia between 12 days in 9 years of age we performed 72 duplexsonographic examinations of the portal system and the hepatic artery. In the control group we investigated 61 healthy children. All investigations were performed with computer sonography (Acuson 128) with a 3.5 MHz...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025481

    authors: Grunert D,Stier B,Schöning M

    更新日期:1990-01-01 00:00:00

  • [Cow's milk allergy: guidelines for the diagnostic evaluation].

    abstract::About 2% of the general population and up to 6% of children suffer from food allergy. Cow's milk is charged with a important role in infancy after weaning, since conventional formula are based on its procession. IgE-mediated and Non-IgE- mediated allergic reactions, which are different in manifestation and pathogenesi...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2006-921357

    authors: Kirchlechner V,Dehlink E,Szepfalusi Z

    更新日期:2007-07-01 00:00:00

  • Leukapheresis and exchange transfusion in children with acute leukemia and hyperleukocytosis. A single center experience.

    abstract:BACKGROUND:The risk of severe complications or death during the initial period of acute leukemia was markedly decreased due to the progress in pediatric oncology and use of simple measures like hyperhydration, forced diuresis, treatment of hyperuricemia, correction of electrolyte and coagulation disturbances and the ca...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0029-1239533

    authors: Haase R,Merkel N,Diwan O,Elsner K,Kramm CM

    更新日期:2009-11-01 00:00:00

  • [New concepts of corticosteroid treatment in pulmonary diseases of the premature infant].

    abstract::Corticosteroids for treatment or prevention of pulmonary disease are milestones in the management of preterm infants nowadays. Prenatal maternal administration as well as postnatal treatment of the mechanically ventilated preterm infant with bronchopulmonary dysplasia (BPD) are considered to be established concepts. H...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1043969

    authors: Krause M

    更新日期:1997-09-01 00:00:00

  • The secretory IgA system.

    abstract::The secretory IgA system is common to all mucosal membranes and is presumably of great importance for their defense. In addition to the secretory IgA antibodies produced in a mucosa in response to a local antigenic stimulus there is a spread of this type of IgA response via committed lymphocytes. They originate from c...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033997

    authors: Hanson LA,Andersson B,Carlsson B,Dahlgren U,Mellander L,Porras O,Svanborg Edén C,Söderström T

    更新日期:1985-07-01 00:00:00

  • Update on Transumbilical Single-Incision Laparoscopic Assisted Appendectomy (TULAA) - Which Children Benefit and What are the Complications?

    abstract:BACKGROUND:Transumbilical laparoscopic-assisted appendectomy (TULAA) is fast and cost-effective since no endoloops, staplers or wound protection devices are used. We analyzed the effects of TULAA as first approach for perforated (PA) and non-perforated (NPA) appendicitis in children. PATIENTS:We performed a retrospect...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0044-101622

    authors: Dübbers M,Nikolaou E,Fuchs H,Fischer J,Alakus H,Leers J,Bruns C,Cernaianu G

    更新日期:2018-07-01 00:00:00

  • Probiotics for prevention of necrotising enterocolitis: an updated meta-analysis.

    abstract::Several randomized controlled trials (RCTs) have investigated the prophylactic use of probiotics in preterm infants aimed at reducing the rate of necrotising enterocolitis (NEC). There are 4 meta-analyses on this subject. 2 more RCTs have been published since these meta-analyses were completed. Each meta-analysis, as ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,meta分析

    doi:10.1055/s-0030-1254113

    authors: Guthmann F,Kluthe C,Bührer C

    更新日期:2010-09-01 00:00:00

  • Allogeneic hematopoietic stem cell transplantation in Glanzmann thrombasthenia complicated by platelet alloimmunization.

    abstract:BACKGROUND:For Thrombasthenia Glanzmann (GT) patients presenting with a severe clinical phenotype due to complete lack of thrombocyte function or increased titres of anti-platelet antibodies hematopoietic stem cell transplantation (SCT) is the only curative therapy. CASE REPORT:We report the case of a 13-month-old boy...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1273726

    authors: Wiegering V,Winkler B,Langhammer F,Wölfl M,Wirbelauer J,Sauer K,Kobsar A,Meyer T,Strauss A,Bakchoul T,Eyrich M,Schlegel PG

    更新日期:2011-05-01 00:00:00

  • [Introduction and critical comparison of clinical scores for characterizing the degree of morbidity of patients with cystic fibrosis].

    abstract::Scoring systems for evaluation of the degree of severity in patients with cystic fibrosis are critically evaluated. Cross-sectional comparison of Shwachman's score, Cooperman's score, Taussig-NIH score, Bernese score and Huang score reveals that advantages and disadvantages of each score exist. In early days used as a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-1025188

    authors: Schöni MH

    更新日期:1993-01-01 00:00:00

  • [Robin-Silverman-Smith (fetal face) syndrome].

    abstract::Report of a case of the fetal face syndrome associated with severe oligophrenia and septum pellucidum cyste in a male patient aged 30 years. The case demonstrates the good prognosis of the hypogenitalism resp. small genitalia; the correct diagnosis in this syndrome can the patients save a plastic of the penis. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046568

    authors: Fehlow P,Walther F,Pfeifer T,Schuchard UM

    更新日期:1995-11-01 00:00:00

  • [Pre- and retrorenal neuroblastoma without kidney displacement].

    abstract::Pre- and retrorenal growing neuroblastomas did not produce any displacement of the kidney or any obstruction in the intravenous pyelogram. The diagnosis was done by ultrasound-scanning as well as biochemically before surgery. The reported cases show that sonography and determination of the catecholamine metabolites ar...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034041

    authors: Burdach SE,Bliesener JA,Evers KG,Gharib M

    更新日期:1983-01-01 00:00:00

  • Diagnostic and therapeutic considerations on inherited platelet disorders in neonates and children.

    abstract::Inherited disorders of platelets constitute a group of rare diseases that give rise to bleeding syndromes of variety severity, with more severe cases being first diagnosed during infancy and childhood. To appropriate diagnose a platelet function disorder during early childhood the knowledge of the physiological charac...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1249065

    authors: Schlegel N,Bardet V,Kenet G,Muntean W,Zieger B,Nowak-Göttl U,Working Group on Standardisation in Perinatal and Pediatric Hemostasis.

    更新日期:2010-05-01 00:00:00

  • [Psychological aspects of radiotherapy of children and adolescents (author's transl)].

    abstract::The increasing importance of radiotherapy in tumor of childhood demands the investigation and consideration of the psychological aspects of this afflicting therapy. In this paper the results obtained by questioning and observing 28 children of different ages, their parents, attendants and employees of several radiolog...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034457

    authors: Poehler A,Riedesser P,Jobke A,Wannenmacher M

    更新日期:1981-05-01 00:00:00

  • [Nutritional Therapy for Children and Adolescents with Autism Spectrum Disorders: What is the Evidence?].

    abstract:BACKGROUND:Autism spectrum disorders (ASDs) are a group of developmental disabilities in childhood and adolescence. Beside genetic predisposition also environmental influences may contribute to the ASD pathogenesis. Family members of children and adolescents with ASD often ask for specific diets to alleviate ASD-associ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0041-110207

    authors: Sausmikat J,Smollich M

    更新日期:2016-03-01 00:00:00

  • [Therapy-related pamphlet for patients in pediatric oncology].

    abstract::This notebook which is of postcard size contains important information in case of emergency and details about the current illness and treatment. It contains follow-up information about the pattern of growth, endocrinological development and assessment of renal tubular function. The necessary follow-up investigations a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046621

    authors: Maass E

    更新日期:1994-07-01 00:00:00

  • [Changes on platelet adhesion, aggregation and production in course of mumps and mumps meningitis (author's transl)].

    abstract::In 20 children with mumps and mumps meningitis thrombocyte functions, the thrombopoiesis and the platelet count were examinated over a four week period. The spontaneous, standardized platelet adhesion and aggregation on silikonized glass surface showed a statistically significant increase from the 5th to the 15th day ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Lemanczyk S,Podolsak B

    更新日期:1977-09-01 00:00:00