Alginate-based encapsulation of cells: past, present, and future.

Abstract:

:Replacing dysfunctional endocrine tissues (eg, islets) with healthy, nonautologous material protected against the immune defense of the patient could soon become a reality. Recent advances have resulted in the development of alginate-based microcapsules that meet the demands of biocompatibility, long-term integrity, and function. Focus on the development of good manufacturing practice-conforming microfluidic chip technology for generation of immunoisolated transplants and on cryopreservation technology will bring the cell-based therapy to the market and clinics.

journal_name

Curr Diab Rep

journal_title

Current diabetes reports

authors

Zimmermann H,Shirley SG,Zimmermann U

doi

10.1007/s11892-007-0051-1

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

314-20

issue

4

eissn

1534-4827

issn

1539-0829

journal_volume

7

pub_type

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