Management of hyperglycemia in hospitalized patients with renal insufficiency or steroid-induced diabetes.

abstract：:After recently being recognized as a feature of the metabolic syndrome, fatty liver has evolved as a key player in the pathogenesis of dyslipidemia. Development of nonalcoholic fatty liver disease comes from an imbalance between the influx and production of fatty acids and the use of fatty acids for oxidation or secre...

journal_title：Current diabetes reports

authors： Adiels M,Taskinen MR,Borén J

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The micro/macrovascular complications of diabetes cause considerable morbidity and premature mortality. The SGLT2 inhibitors are the first diabetes medications with significant benefits on microvascular disease (nephropathy) and macrovascular cardiovascular disease. In this review, we evaluate one of ...

journal_title：Current diabetes reports

authors： Ekanayake P,Hupfeld C,Mudaliar S

更新日期：2020-11-23 00:00:00

abstract：:Attention to meal-related insulin replacement in type 2 diabetes is important as insulin deficiency progresses. The physiology in type 2 and type 1 diabetes differs, and optimal use of basal-bolus therapy in type 2 diabetes requires attention to such issues as the role for oral medications, residual endogenous insulin...

journal_title：Current diabetes reports

authors： Karl DM

更新日期：2004-10-01 00:00:00

abstract：:Unfortunately, the only approved medical treatment for type 1 diabetes mellitus (DM) is insulin, despite the fact that tight control cannot be reached without some serious side effects such as hypoglycemia and weight gain. More and more importance is now shifted towards developing new drugs that can reach a better gly...

journal_title：Current diabetes reports

authors： Issa CM,Azar ST

更新日期：2012-10-01 00:00:00

abstract：:Charcot neuro-osteoarthropathy (CN) is among the most devastating complications of neuropathy and now most commonly occurs in the feet of diabetic patients. Because it is relatively rare and because most patients and practitioners do not expect major bone pathology in the absence of significant pain, CN is often misdi...

journal_title：Current diabetes reports

authors： Ulbrecht JS,Wukich DK

更新日期：2008-12-01 00:00:00

abstract：:The epidemic of childhood obesity has led to a remarkable increase in the prevalence of type 2 diabetes (T2D) among youth worldwide. The decreasing age at onset of T2D has alarming public health implications. In particular, the longer duration of the disease, as well as the faster onset and progression of T2D related ...

journal_title：Current diabetes reports

authors： Giannini C,Caprio S

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity in the older adult is a burgeoning health epidemic that leads to increased morbidity, disability, and institutionalization. This review presents a brief overview of geriatric-specific consequences of obesity by highlighting the risks and benefits of intentional weight loss. RECENT FINDINGS:In...

journal_title：Current diabetes reports

authors： DiMilia PR,Mittman AC,Batsis JA

更新日期：2019-11-04 00:00:00

abstract：PURPOSE OF REVIEW:Pancreas transplantation remains the best long-term treatment option to achieve euglycemia and freedom from insulin in patients with labile diabetes mellitus. It is an approved procedure for type 1 (T1DM), but it is still considered controversial for type 2 diabetes mellitus (T2DM). RECENT FINDINGS:T...

journal_title：Current diabetes reports

authors： Gruessner AC,Laftavi MR,Pankewycz O,Gruessner RWG

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity is closely linked with the pathogenesis of type 2 diabetes (T2DM) and cardiovascular disease (CVD), and whilst smoking cessation is associated with weight gain, there are concerns that this weight gain may offset the benefit of CVD risk reduction especially in those with considerable post-cess...

journal_title：Current diabetes reports

authors： Kos K

更新日期：2020-12-08 00:00:00

abstract：:Among the spectrum of risk for diabetic foot disease conferred by chronic kidney disease (CKD), end-stage renal disease (ESRD) has emerged as a novel independent risk factor. Apart from the classical triad of neuropathy, infection, and peripheral arterial disease that operate in these individuals, the risk is further ...

journal_title：Current diabetes reports

authors： Ndip A,Lavery LA,Boulton AJ

更新日期：2010-08-01 00:00:00

abstract：:The endothelium has several diverse functions in maintaining vascular integrity in terms of structure and function. Two key vasodilators, nitric oxide (NO) and prostacyclin, maintain the vascular pathway, inhibit platelet aggregation, and are antithrombotic. More recently, they have been shown to be anti-inflammatory,...

journal_title：Current diabetes reports

authors： Dandona P

更新日期：2002-08-01 00:00:00

abstract：:Although a clear relationship exists between glycosylated hemoglobin and cardiovascular (CV) disease in individuals with type 2 diabetes mellitus (T2DM) in epidemiologic studies, data from prospective studies are less clear. Earlier prospective studies examining intensive glucose lowering suffered from a lack of stati...

journal_title：Current diabetes reports

authors： Zarich SW

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Studies have shown that disasters may exacerbate the comorbidities in vulnerable populations such as those with a pre-existing chronic medical condition like diabetes. This article highlights recent studies that look at the impact of disasters on people with diabetes and also shows recent resources fo...

journal_title：Current diabetes reports

authors： Allweiss P

更新日期：2019-11-20 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate the treatment of type 2 diabetes from a cardiologist's view. RECENT FINDINGS:A new era in the treatment of type 2 diabetes began for the cardiologist in 2015 with the publication of the EMPA-REG outcome trial finding a significant reduction in CV death with empagliflozin (oral sodium-gluc...

journal_title：Current diabetes reports

authors： Chilton RJ,Gallegos KM,Silva-Cardoso J,Oliveros R,Pham S

更新日期：2018-11-08 00:00:00

abstract：PURPOSE OF REVIEW:This paper aims to examine how self-regulation (i.e., cognition, emotion) and social-regulation (i.e., parents, friends, romantic partners) are interrelated risk and protective factors for type 1 diabetes management during late adolescence and emerging adulthood. RECENT FINDINGS:Problems in cognitive...

journal_title：Current diabetes reports

authors： Wiebe DJ,Berg CA,Mello D,Kelly CS

更新日期：2018-03-21 00:00:00

abstract：:Neonatal hypoglycemia is an important consequence for the infant of the mother with diabetes. We have reviewed 24 published papers of various protocols for control of glucose in pregnant diabetic women during labor and delivery including our own published work. A relationship of maternal glucose during labor and neona...

journal_title：Current diabetes reports

authors： Ryan EA,Al-Agha R

更新日期：2014-01-01 00:00:00

abstract：:Continuous glucose monitoring (CGM) is an emerging technology that provides a continuous measure of interstitial glucose levels. In addition to providing a more complete pattern of glucose excursions, CGMs utilize real-time alarms for thresholds and predictions of hypo- and hyperglycemia, as well as rate of change ala...

journal_title：Current diabetes reports

authors： DeSalvo D,Buckingham B

更新日期：2013-10-01 00:00:00

abstract：:Diabetic nephropathy has become the main cause of renal failure, but unfortunately the intimate mechanisms leading to the development and progression of renal injury are not yet fully known. Activated innate immunity and inflammation are relevant factors in the pathogenesis of diabetes. Moreover, different inflammator...

journal_title：Current diabetes reports

authors： Mora C,Navarro JF

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The Diabetes Prevention Program (DPP) is an evidence-based lifestyle change program for prediabetes that is associated with a 58% reduction in 3-year diabetes incidence, and it has been supported by the American Medical Association and the Centers for Disease Control and Prevention. However, 9 in 10 p...

journal_title：Current diabetes reports

authors： Jasik CB,Joy E,Brunisholz KD,Kirley K

更新日期：2018-08-08 00:00:00

abstract：PURPOSE OF REVIEW:To provide an updated summary of discoveries made to date resulting from genome-wide association study (GWAS) and sequencing studies, and to discuss the latest loci added to the growing repertoire of genetic signals predisposing to type 1 diabetes (T1D). RECENT FINDINGS:Genetic studies have identifie...

journal_title：Current diabetes reports

authors： Bakay M,Pandey R,Grant SFA,Hakonarson H

更新日期：2019-11-04 00:00:00

abstract：:Beta cell replacement therapy has been proposed as a novel therapy for the treatment of type 1 diabetes. The proof of concept has been demonstrated with successful islet allotransplantation. Islet xenotransplantation has been proposed as an alternative, more reliable, and infinite source of beta cells. The advantages ...

journal_title：Current diabetes reports

authors： O'Connell PJ,Cowan PJ,Hawthorne WJ,Yi S,Lew AM

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Currently, the diagnosis of gestational diabetes mellitus (GDM) lacks uniformity. Several controversies are still under debate, especially on the method of screening and diagnosis. This review focuses on recent literature and provides current evidence for the screening and diagnosis of GDM. RECENT FI...

journal_title：Current diabetes reports

authors： Kuo CH,Li HY

更新日期：2019-12-04 00:00:00

abstract：:The occurrence and progression of nephropathy associated with early onset type 2 diabetes (T2D) is a consequence of the ongoing epidemic of childhood obesity. Minimal evidence regarding treatment effectiveness of renovascular comorbidities in youth with early onset T2D is available, due to the relatively recent emerge...

journal_title：Current diabetes reports

authors： Solis-Herrera C,Triplitt CL,Lynch JL

更新日期：2014-02-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) plays a pivotal role in the development of diabetic macular edema (DME), the leading cause of vision loss among working-aged individuals. A decade of clinical trials demonstrated that drugs that bind soluble VEGF restore the integrity of the blood-retinal barrier, resolve macu...

journal_title：Current diabetes reports

authors： Stewart MW

更新日期：2014-08-01 00:00:00

abstract：:The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of type 2 diabetes mellitus to the chromosome 1q21-25 region in at least eight independent studies. More than 26 candidate genes have already been evaluated, but to date none explain the evidence for linkage in this gene-dense region....

journal_title：Current diabetes reports

authors： Das SK,Elbein SC

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Appetitive behaviors are mediated through homeostatic and reward signaling of brain circuits. There has been increasing interest in the use of neuromodulation techniques aimed at targeting brain regions such as the lateral prefrontal and subcortical regions associated with dysregulation of eating beha...

journal_title：Current diabetes reports

authors： Dendy R,Stinson EJ,Guerithault N,Gluck ME

更新日期：2019-12-02 00:00:00

abstract：:Type 1 diabetes (T1D) is a complex chronic disease that has many facets for successful management. The burden of this management falls largely on the individual and their family members. Self-management has a major influence on T1D health outcomes, and with successful management, children and adolescents with T1D can ...

journal_title：Current diabetes reports

authors： Naranjo D,Mulvaney S,McGrath M,Garnero T,Hood K

更新日期：2014-01-01 00:00:00

abstract：:Type 2 diabetes is the result of a progressive impairment of pancreatic beta-cell function in the setting of worsening insulin resistance. Studies in high-risk populations have demonstrated that during progression to diabetes, beta cells have declining function and lose the first phase of insulin secretion, resulting ...

journal_title：Current diabetes reports

authors： Steppel JH,Horton ES

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Great strides have recently been made in elucidating the role of genetic sequence variation in diabetes pathogenesis. Increasingly, studies are focusing on other factors that may contribute to the pathogenesis of diabetes, such as epigenetics, a term "traditionally" encompassing changes to the DNA tha...

journal_title：Current diabetes reports

authors： Zhang H,Pollin TI

更新日期：2018-10-02 00:00:00

abstract：:Only 21 % of adolescents with type 1 diabetes (T1D) meet glycemic goals set forth by the American Diabetes Association. Adherence to therapy is a particular concern in this population, and the association between poor adherence and worsening glycemic control indicates that there is a critical need to improve adherence...

journal_title：Current diabetes reports

authors： Datye KA,Moore DJ,Russell WE,Jaser SS

更新日期：2015-08-01 00:00:00