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Effect of the combination of organic and inorganic filters on the Sun Protection Factor (SPF) determined by in vitro method.

Abstract：

:This paper describes the effect on Sun Protection Factor (SPF) of the combination of inorganic and organic filters in sunscreen products as determined by an in vitro method. O/W emulsions containing inorganic filters, such as titanium dioxide and zinc oxide, combined with 18 EU-authorized UV-B organic filters were tested. SPF measurements were carried out using a spectrophotometer equipped with an integrating sphere. This study observed a synergic effect when titanium dioxide was combined with either anisotriazine or octyldimethylPABA. The combination of zinc oxide with 11 UV-B organic filters also exhibited a similar synergy; however, the measured SPF was systematically lower than the protection factor achieved with titanium dioxide.

journal_name

Int J Pharm

journal_title

International journal of pharmaceutics

authors

El-Boury S,Couteau C,Boulande L,Paparis E,Coiffard LJ

doi

10.1016/j.ijpharm.2007.05.047

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

1-5

issue

1-2

eissn

0378-5173

issn

1873-3476

pii

S0378-5173(07)00458-9

journal_volume

340

pub_type

杂志文章

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