Infusion of neuropeptide Y into CA3 region of hippocampus produces antidepressant-like effect via Y1 receptor.

abstract：:For memory retrieval, pattern completion is a crucial process that restores memories from partial or degraded cues. Neurocognitive aging models suggest that the aged memory system is biased toward pattern completion, resulting in a behavioral preference for retrieval over encoding of memories. Here, we built on our pr...

journal_title：Hippocampus

authors： Vieweg P,Riemer M,Berron D,Wolbers T

更新日期：2019-04-01 00:00:00

abstract：:Neuronal oscillations and cross-frequency interactions in the rat hippocampus relate in important ways to memory processes and serve as a model for studying oscillatory activity in cognition more broadly. We report here that hippocampal synchrony (CA3-CA1 coherence) increased markedly in the low gamma range as rats we...

journal_title：Hippocampus

authors： Trimper JB,Stefanescu RA,Manns JR

更新日期：2014-03-01 00:00:00

abstract：:This study examines the extent to which simultaneous olfactory discrimination learning increases spine density on hippocampal CA1 pyramidal neurons in C57BL/6J (C57) and DBA/2J (DBA) inbred mice, characterized by spontaneous differences in hippocampal plasticity and hippocampus-related learning. The behavioral data fi...

journal_title：Hippocampus

authors： Restivo L,Roman FS,Ammassari-Teule M,Marchetti E

更新日期：2006-01-01 00:00:00

abstract：:The influence of the learning process on the persistence of the newly acquired behavior is relevant both for our knowledge of the learning/memory mechanisms and for the educational policy. However, it is unclear whether during an operant conditioning process with a continuous reinforcement paradigm, individual differe...

journal_title：Hippocampus

authors： Gradari S,Pérez-Domper P,Butler RG,Martínez-Cué C,de Polavieja GG,Trejo JL

更新日期：2016-07-01 00:00:00

abstract：:L-aspartate is the amino-acid residue most susceptible to spontaneous isomerization. This denaturation causes an alteration in the biological activity of the protein and is regarded as an aging process of the protein. Protein L-isoaspartyl methyltransferase (PIMT) repairs this post-translational modification and thus ...

journal_title：Hippocampus

authors： Ikegaya Y,Yamada M,Fukuda T,Kuroyanagi H,Shirasawa T,Nishiyama N

更新日期：2001-01-01 00:00:00

abstract：:In urethane-anesthetized rats, cortical regions which provide distal dendritic excitation of the dentate gyrus and CA1 of the dorsal hippocampus were studied using current source density analysis. Electrical stimulation of the lateral perforant path (LPP) in the lateral angular bundle, lateral entorhinal cortex (LEC),...

journal_title：Hippocampus

authors： Canning KJ,Leung LS

更新日期：1997-01-01 00:00:00

abstract：:Gelsolin is an actin-binding protein that regulates actin filament-severing and capping activity in the various processes of cell motilities. Here, we report the expression of gelsolin mRNA and protein in the hippocampus following transections of the entorhinal afferents. Northern blot analysis showed that transcript ...

journal_title：Hippocampus

authors： Dong JH,Ying GX,Liu X,Wang WY,Wang Y,Ni ZM,Zhou CF

更新日期：2006-01-01 00:00:00

abstract：:Intracellular recording and computational modelling suggest that interactions of subthreshold membrane potential oscillation frequency in different dendritic branches of entorhinal cortex stellate cells could underlie the functional coding of continuous dimensions of space and time. Among other things, these interacti...

journal_title：Hippocampus

authors： Hasselmo ME,Giocomo LM,Zilli EA

更新日期：2007-01-01 00:00:00

abstract：:The growth arrest specific 5 (gas5) is a noncoding protein gene that hosts small nucleolar RNAs. Based on the observation that gas5 RNA level in the brain is highest in the hippocampus and remarkably enhanced in aged mice, we tested the hypothesis that gas5 is involved in functions controlled by the hippocampus and kn...

journal_title：Hippocampus

authors： Meier I,Fellini L,Jakovcevski M,Schachner M,Morellini F

更新日期：2010-09-01 00:00:00

abstract：:Changes in synaptic efficacy and morphology have been proposed as mechanisms underlying learning and memory processes. In our previous studies, high frequency stimulation (HFS) sufficient to induce LTP at the hippocampal mossy fiber (MF) pathway, leads to MF synaptogenesis, in a prominent contralateral form, at the st...

journal_title：Hippocampus

authors： Schjetnan AG,Escobar ML

更新日期：2012-01-01 00:00:00

abstract：:Converging behavioral, electrophysiological, and neurochemical data suggest that lesions to the peripheral vestibular system result in impairment of the hippocampus. Nonetheless, relatively few studies have examined the hippocampus or behavior related to it, over a long period of time following the lesion, to determin...

journal_title：Hippocampus

authors： Zheng Y,Goddard M,Darlington CL,Smith PF

更新日期：2007-01-01 00:00:00

abstract：:In contextual fear conditioning (CFC), the use of pharmacological and lesion approaches has helped to understand that there are differential roles for the dorsal hippocampus (DH) and the ventral hippocampus (VH) in the acquisition, consolidation and retrieval phases. Concomitant analysis of the DH and the VH in indivi...

journal_title：Hippocampus

authors： Sase S,Sase A,Sialana FJ Jr,Gröger M,Bennett KL,Stork O,Lubec G,Li L

更新日期：2015-12-01 00:00:00

abstract：:Rats use time-of-day cues to modulate learned taste aversion memories. If adult rats are accustomed to drinking saline in the evening and they receive a lithium chloride injection after drinking saline in the morning, they form a stronger aversion to saline than rats that were conditioned after drinking saline at the ...

journal_title：Hippocampus

authors： Manrique T,Morón I,Ballesteros MA,Guerrero RM,Fenton AA,Gallo M

更新日期：2009-01-01 00:00:00

abstract：:We have studied 5-hydroxytryptamine (5-HT) release in the hippocampal formation following electrical stimulation of the dorsal and median raphé nuclei in the behaving rat. The primary finding in this study is a decrease in neuronal release of serotonin in the dorsal hippocampal formation following electrical stimulati...

journal_title：Hippocampus

authors： Mokler DJ,Lariviere D,Johnson DW,Theriault NL,Bronzino JD,Dixon M,Morgane PJ

更新日期：1998-01-01 00:00:00

abstract：:With the aim of establishing a quantitative structural basis for comparative and experimental studies, the volumes of the hippocampal subdivisions and the total number of neurons in each subdivision were estimated in domestic pig brains using modern stereological techniques. In addition to a detailed description of th...

journal_title：Hippocampus

authors： Holm IE,West MJ

更新日期：1994-02-01 00:00:00

abstract：:Granule cells with recurrent basal dendrites (RBDs) were previously reported in both control and epileptic rats. RBDs are dendrites that arise from the basal half of granule cell bodies and curve toward and extend into the molecular layer. They are increased in frequency in the pilocarpine model of epilepsy. The prese...

journal_title：Hippocampus

authors： Dashtipour K,Yan XX,Dinh TT,Okazaki MM,Nadler JV,Ribak CE

更新日期：2002-01-01 00:00:00

abstract：:Nearby grid cells have been observed to express a remarkable degree of long-range order, which is often idealized as extending potentially to infinity. Yet their strict periodic firing and ensemble coherence are theoretically possible only in flat environments, much unlike the burrows which rodents usually live in. Ar...

journal_title：Hippocampus

authors： Stella F,Urdapilleta E,Luo Y,Treves A

更新日期：2020-04-01 00:00:00

abstract：:The mechanisms underlying memory are under intense investigation. One of the most promising candidates at the cellular level is long-term potentiation (LTP). Numerous pharmacological and molecular genetic manipulations have led to alteration in both LTP and memory. However, the causal relationship between these phenot...

journal_title：Hippocampus

authors： Gerlai R

更新日期：2002-01-01 00:00:00

abstract：:In rodents, pyramidal cell firing patterns from waking may be replayed in nonrapid eye movement sleep (NREM) sleep during hippocampal sharp wave ripples (HC-SWR). In humans, HC-SWR have only been recorded with electrodes implanted to localize epileptogenicity. Here, we characterize human HC-SWR with rigorous rejection...

journal_title：Hippocampus

authors： Jiang X,Gonzalez-Martinez J,Cash SS,Chauvel P,Gale J,Halgren E

更新日期：2020-06-01 00:00:00

abstract：:In this review, we aim to reappraise the organization of intrinsic and extrinsic networks of the entorhinal cortex with a focus on the concept of parallel cortical connectivity streams. The concept of two entorhinal areas, the lateral and medial entorhinal cortex, belonging to two parallel input-output streams mediati...

journal_title：Hippocampus

authors： Nilssen ES,Doan TP,Nigro MJ,Ohara S,Witter MP

更新日期：2019-12-01 00:00:00

abstract：:Vasopressin receptors are present in both the developing and mature dentate gyrus of the rat brain and are of the V1 vasopressor type. Because vasopressin has been shown to influence memory function when injected into the dentate gyrus, the influence of this peptide on an electrophysiological model of learning and mem...

journal_title：Hippocampus

authors： Chen C,Díaz Brinton RD,Shors TJ,Thompson RF

更新日期：1993-04-01 00:00:00

abstract：:Septal nuclei are suggested to work as an interface between the hippocampal formation, involved in higher cognitive functions, and the hypothalamus, involved in motivational behaviors such as feeding, drinking, and intracranial self-stimulation. In the present study, to elucidate a role of the septal nuclei in motivat...

journal_title：Hippocampus

authors： Nishijo H,Kita T,Tamura R,Eifuku S,Terasawa K,Ono T

更新日期：1997-01-01 00:00:00

abstract：:The hippocampus and the medial temporal lobe cortex [medial temporal lobe cortices (MTLC)] both contribute to long-term memory. Although their contributions are thought to be dissociable, the nature of the representations that each region supports remains unclear. The Complementary Learning Systems (CLS) modeling appr...

journal_title：Hippocampus

authors： Duff MC,Warren DE,Gupta R,Vidal JP,Tranel D,Cohen NJ

更新日期：2012-05-01 00:00:00

abstract：:Structural integrity of the human hippocampus is widely acknowledged to be necessary for the successful encoding and retrieval of autobiographical memories. However, evidence for an association between hippocampal volume and the ability to recall such memories in healthy individuals is mixed. Here we examined this iss...

journal_title：Hippocampus

authors： Barry DN,Clark IA,Maguire EA

更新日期：2020-12-15 00:00:00

abstract：:The human medial temporal lobe (MTL) is known to be involved in declarative memory, yet the exact contributions of the various MTL structures are not well understood. In particular, the data as to whether the hippocampal region is preferentially involved in the encoding and/or retrieval of associative memory have not ...

journal_title：Hippocampus

authors： Kirwan CB,Stark CE

更新日期：2004-01-01 00:00:00

abstract：:Several recent studies have compared episodic and spatial memory in neuroimaging paradigms in order to understand better the contribution of the hippocampus to each of these tasks. In the present study, we build on previous findings showing common neural activation in default network areas during episodic and spatial ...

journal_title：Hippocampus

authors： Robin J,Hirshhorn M,Rosenbaum RS,Winocur G,Moscovitch M,Grady CL

更新日期：2015-01-01 00:00:00

abstract：:Sleep is important for memory consolidation, and an abundant literature suggests that reactivation in the hippocampus during sleep is instrumental to this process. Yet, the current interpretation of activity during sharp-waves ripples (SWRs), as replay of wake experiences, relies on hypotheses that, while widely accep...

journal_title：Hippocampus

authors： Laventure S,Benchenane K

更新日期：2020-01-01 00:00:00

abstract：:Synaptic responses mediated by the N-methyl-D-aspartate receptor (NMDAr) and non-NMDAr activation were compared in CA1 hippocampal region of young (3-4 months old) and aged (25-33 months old) Sprague-Dawley rats with the use of ex vivo extracellular recordings techniques. In aged rats, the amplitude of the NMDAr-media...

journal_title：Hippocampus

authors： Jouvenceau A,Dutar P,Billard JM

更新日期：1998-01-01 00:00:00

abstract：:Although the parahippocampal cortex (PHc) is known to be critical for memory formation, little is known about what is encoded by this area. Using multi-voxel pattern analysis of high-resolution functional magnetic resonance imaging (MRI) data, we examined responses to blocks of categorically coherent stimuli and found...

journal_title：Hippocampus

authors： Diana RA,Yonelinas AP,Ranganath C

更新日期：2008-01-01 00:00:00

abstract：:Metabolic integrity of glial cells in field CA1 of the guinea pig hippocampus is critical to maintenance of synaptic transmission (Keyser and Pellmar [1994] Glia 10:237-243). To determine if this tight glial-neuronal coupling is equally important in other brain regions, we compared the effect of fluoroacetate (FAC), a...

journal_title：Hippocampus

authors： Keyser DO,Pellmar TC

更新日期：1997-01-01 00:00:00