Hippocampus of the domestic pig: a stereological study of subdivisional volumes and neuron numbers.

abstract：:We have shown previously that chronic nicotine treatment reverses adult-onset hypothyroidism-induced impairment of late-phase long-term potentiation (L-LTP) in area CA1 of the hippocampus. In the present study, basal and stimulated levels of signaling molecules essential for the expression of L-LTP were determined in ...

journal_title：Hippocampus

authors： Alzoubi KH,Aleisa AM,Alkadhi KA

更新日期：2007-01-01 00:00:00

abstract：:Previous research has revealed that the functional components of spatial cognition are lateralized in the forebrain of birds, including the hippocampal formation (HF). To investigate how HF cells in the left and right avian brain may differentially participate in representations of space, we recorded single-units from...

journal_title：Hippocampus

authors： Siegel JJ,Nitz D,Bingman VP

更新日期：2006-01-01 00:00:00

abstract：:The importance of the perirhinal cortex for visual recognition memory performance is undisputed. However, it has not been clear whether its contribution to performance is mainly perceptual, or mainly mnemonic, or whether the perirhinal cortex contributes to both perception and memory. We determined the effects of medi...

journal_title：Hippocampus

authors： Buffalo EA,Reber PJ,Squire LR

更新日期：1998-01-01 00:00:00

abstract：:Although a large body of evidence indicates that sleep plays an important role in learning and memory processes, the actual existence of a sleep-dependent spatial memory consolidation has been not firmly established. Here, by using a computerized 3D virtual navigation tool, we were able to show that topographical orie...

journal_title：Hippocampus

authors： Ferrara M,Iaria G,Tempesta D,Curcio G,Moroni F,Marzano C,De Gennaro L,Pacitti C

更新日期：2008-01-01 00:00:00

abstract：:Previous studies have shown that estrogens, originating from ovaries, have a wide variety of estrogen receptor (ER)-mediated effects in the hippocampus. In the present study, we have investigated whether estrogens, which are synthesized in the hippocampus, could induce these effects as well. As a parameter, we used ER...

journal_title：Hippocampus

authors： Prange-Kiel J,Wehrenberg U,Jarry H,Rune GM

更新日期：2003-01-01 00:00:00

abstract：:Previous investigation of CA1-evoked subicular responses has used either single low-frequency pulses (LF), paired-pulses (PP), or high-frequency bursts. Here we test for the first time how subiculum responds to naturalistic stimulation trains (NSTs). We recorded CA1-evoked field potentials from dorsal rat subiculum in...

journal_title：Hippocampus

authors： Tunstall B,Agnew ZK,Panzeri S,Gigg J

更新日期：2010-02-01 00:00:00

abstract：:The goal of the present research was to assess the degree to which a pattern completion process operates in cue-induced relapse to cocaine-seeking behavior. Using a novel cue-preference version of the place preference task, rats were administered cocaine or saline, which resulted in a preference for the cocaine-paired...

journal_title：Hippocampus

authors： Kesner RP,Kirk RA,Clark JK,Moore A,Keefe K

更新日期：2016-07-01 00:00:00

abstract：:It has been well-established that cell proliferation and neurogenesis in the adult mouse dentate gyrus (DG) can be regulated by voluntary exercise. Recent evidence has suggested that the effects of voluntary exercise can in turn be influenced by environmental factors that regulate the amount of stress an animal is exp...

journal_title：Hippocampus

authors： Kannangara TS,Webber A,Gil-Mohapel J,Christie BR

更新日期：2009-10-01 00:00:00

abstract：:Entorhinal cortex lesion (ECL) leads to anterograde degeneration of perforant path axons and is known to induce a rapid and intense reaction of astrocytes and microglial cells in the deafferented dentate gyrus. Phagocytosis of degenerating axons involves the establishment and maintenance of cell-matrix and cell-cell i...

journal_title：Hippocampus

authors： Hailer NP,Bechmann I,Heizmann S,Nitsch R

更新日期：1997-01-01 00:00:00

abstract：:The electrically induced increase in hippocampal synaptic strength known as long-term potentiation (LTP) is thought to involve some of the same mechanisms as those mediating information storage during spatial learning. Physiological saturation of synaptic weights might therefore be expected to occlude spatial learning...

journal_title：Hippocampus

authors： Jeffery KJ,Morris RG

更新日期：1993-04-01 00:00:00

abstract：:Functional differences in the anterior and posterior hippocampus during episodic memory processing have not been examined in human electrophysiological data. This is in spite of strong evidence for such differences in rodent data, including greater place cell specificity in the dorsal hippocampus, greater sensitivity ...

journal_title：Hippocampus

authors： Lin JJ,Rugg MD,Das S,Stein J,Rizzuto DS,Kahana MJ,Lega BC

更新日期：2017-10-01 00:00:00

abstract：:Episodic memory deficits are evident in late-life depression (LLD) and are associated with subtle synaptic and neurochemical changes in the medial temporal lobes (MTL). However, the particular mechanisms by which memory impairment occurs in LLD are currently unknown. We tested older adults with (DS+) and without (DS-)...

journal_title：Hippocampus

authors： Leal SL,Noche JA,Murray EA,Yassa MA

更新日期：2017-04-01 00:00:00

abstract：:The molecular mechanisms of regionalization of the medial pallium (MP), the anlage of the hippocampus, and transitional (cingulate and retrosplenial) cortices are largely unknown. Previous analyses have outlined an important role of the transcription factor (TF) Zbtb20 for hippocampal CA1 field specification (Nielsen ...

journal_title：Hippocampus

authors： Rosenthal EH,Tonchev AB,Stoykova A,Chowdhury K

更新日期：2012-11-01 00:00:00

abstract：:Sleep is important for memory consolidation, and an abundant literature suggests that reactivation in the hippocampus during sleep is instrumental to this process. Yet, the current interpretation of activity during sharp-waves ripples (SWRs), as replay of wake experiences, relies on hypotheses that, while widely accep...

journal_title：Hippocampus

authors： Laventure S,Benchenane K

更新日期：2020-01-01 00:00:00

abstract：:Rats were trained on an operant conditional discrimination in which an ambiguous stimulus (X) indicated both the occasions on which responding in the presence of a second cue (A) would be reinforced and the occasions on which responding in the presence of a third cue (B) would not be reinforced (X --> A+, A-, X --> B-...

journal_title：Hippocampus

authors： Han JS,Gallagher M,Holland P

更新日期：1998-01-01 00:00:00

abstract：:Recent studies have established that environmental factors can modify hippocampal structure and enhance function in adult rodents, but the extent to which genes and the environment exert differential contributions to hippocampal structural integrity in humans is unknown. Here, we applied the twin model in a large samp...

journal_title：Hippocampus

authors： Sullivan EV,Pfefferbaum A,Swan GE,Carmelli D

更新日期：2001-01-01 00:00:00

abstract：:The induction of long-lasting memory storage depends on the behavioral state of humans and animals. This behavioral state is mediated by neuromodulatory systems, like the cholinergic-septum-hippocampal circuit. Cholinergic neurotransmission is known to affect short-term activity-dependent plasticity in various brain a...

journal_title：Hippocampus

authors： Navakkode S,Korte M

更新日期：2012-02-01 00:00:00

abstract：:A striking similarity has been suggested between past and future thinking in Alzheimer's Disease (AD), a similarity attributable to abnormalities in common modular cognitive functions and neuroanatomical substrates. This study extends this literature by identifying specific executive function deficits underlying past ...

journal_title：Hippocampus

authors： El Haj M,Antoine P,Kapogiannis D

更新日期：2015-11-01 00:00:00

abstract：:Longitudinal studies on patients for schizophrenia suggest that functional brain perturbations precede the onset of symptoms. Rats with a neonatal ventral hippocampal lesion (NVHL) are considered as a heuristic neurodevelopmental model of schizophrenia. We characterized basal metabolic changes observed in NVHL rats be...

journal_title：Hippocampus

authors： François J,Koning E,Ferrandon A,Sandner G,Nehlig A

更新日期：2010-07-01 00:00:00

abstract：:The role of the hippocampus in retrograde amnesia remains controversial and poorly understood. Two cases are reported of discrete bilateral hippocampal damage, one of which was a rare case of limbic encephalitis secondary to the human herpes virus 6. Detailed memory testing showed marked anterograde memory impairment,...

journal_title：Hippocampus

authors： Kapur N,Brooks DJ

更新日期：1999-01-01 00:00:00

abstract：:By acting on serotonin 5-HT2A receptors (5-HT2A Rs), serotonergic psychedelic drugs induce perceptual and visual hallucinations by increasing neuronal excitability and altering visual-evoked neuronal responses. The present study was designed to examine whether the perceptual alterations induced by a serotonergic psych...

journal_title：Hippocampus

authors： Zhang G,Cinalli D,Stackman RW Jr

更新日期：2017-05-01 00:00:00

abstract：:Nuclear factor-kappa B (NFκB) signal is essential for neuronal survival and its activation may protect neuron against various stimuli. Since purinergic signals activate NFκB through the P2X7 receptor, we investigated the distinct pattern of NF-κB phosphorylation in neurons by P2X7 receptor activation following status ...

journal_title：Hippocampus

authors： Kim JE,Kim DS,Jin Ryu H,Il Kim W,Kim MJ,Won Kim D,Young Choi S,Kang TC

更新日期：2013-06-01 00:00:00

abstract：:In a comparative approach, the anatomical organization of the hippocampus was investigated in two species of megachiropteran bats, the grey-headed flying fox, Pteropus poliocephalus, and the little red flying fox, Pteropus scapulatus. In general, the cytoarchitectonic appearance of the flying fox hippocampus correspon...

journal_title：Hippocampus

authors： Buhl EH,Dann JF

更新日期：1991-04-01 00:00:00

abstract：:Persistent neural activity lasting for seconds after transient stimulation has been observed in several brain areas. This activity has been taken to be indicative of the integration of inputs on long time scales. Passive membrane properties render neural time constants to be on the order of milliseconds. Intense synap...

journal_title：Hippocampus

authors： Huhn Z,Orbán G,Erdi P,Lengyel M

更新日期：2005-01-01 00:00:00

abstract：:Neurogenesis persists in the adult rat rostral forebrain subventricular zone (SVZ) and is stimulated by status epilepticus (SE). More caudal SVZ (cSVZ) neural progenitors migrate to the hippocampus after ischemic injury and contribute to CA1 pyramidal cell regeneration. Because SE also damages the hippocampus, we exam...

journal_title：Hippocampus

authors： Parent JM,von dem Bussche N,Lowenstein DH

更新日期：2006-01-01 00:00:00

abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP), a neurotrophic and neuromodulatory peptide, was recently shown to enhance NMDA receptor-mediated currents in the hippocampus (Macdonald, et al. 2005. J Neurosci 25:11374-11384). To check if PACAP might also modulate AMPA receptor function, we tested its effec...

journal_title：Hippocampus

authors： Costa L,Santangelo F,Li Volsi G,Ciranna L

更新日期：2009-01-01 00:00:00

abstract：:Neuropsychologists have clearly implicated the hippocampus in the consolidation of memory, particularly episodic memory, the mental replay of past experiences. When recorded from behaving animals, by far the most obvious firing pattern of the primary neurons of the hippocampus is the place field: a cell tends to fire ...

journal_title：Hippocampus

authors： Kentros C

更新日期：2006-01-01 00:00:00

abstract：:Light and electron microscopic immunocytochemical techniques were used to study the interneuron population staining for somatostatin (SRIF) in cultured slices of rat hippocampus. The SRIF immunoreactive somata were most dense in stratum oriens of areas CA1 and CA3, and in the dentate hilus. Somatostatin immunoreactive...

journal_title：Hippocampus

authors： Kunkel DD,Nguyen LB,Harrigan MR,Schwartzkroin PA,Malouf AT

更新日期：1994-04-01 00:00:00

abstract：:To minimize the variability in the extent of lesions made by injections of the excitotoxin ibotenic acid in rhesus monkeys, we developed and validated an MRI-based method to determine the efficacy of the injections soon after surgery. T2-weighted MR images were obtained 6-11 days after surgery from 17 brain hemisphere...

journal_title：Hippocampus

authors： Málková L,Lex CK,Mishkin M,Saunders RC

更新日期：2001-01-01 00:00:00

abstract：:C57 and DBA mice were trained in a crossed maze to assess possible strain differences in place or response learning as a function of training duration (8 or 17 days) and extramaze cueing conditions. The first condition consisted of a diffuse visually cued environment (rich cueing). The second was the same plus an expl...

journal_title：Hippocampus

authors： Passino E,Middei S,Restivo L,Bertaina-Anglade V,Ammassari-Teule M

更新日期：2002-01-01 00:00:00