High survivin expression is associated with favorable outcome in advanced primary oral squamous cell carcinoma after radiation therapy.

abstract：:In this study the antigenic profile of Hodgkin (H) and Sternberg-Reed (SR) cells from cases of Hodgkin's disease was analysed using a large panel of monoclonal and polyclonal antibodies reactive with cells of lymphoid and haemotopoietic origin. The aim of this investigation was, firstly, to throw light on the origin o...

journal_title：International journal of cancer

authors： Stein H,Gerdes J,Schwab U,Lemke H,Mason DY,Ziegler A,Schienle W,Diehl V

更新日期：1982-10-15 00:00:00

abstract：:A marked increase in natural killer (NK) activity is observed with lymphoid cells prepared from SJL/J mouse spleen and lymph nodes, in which a transplantable reticulum-cell neoplasm (RCN) is growing. The killer cells are non-adherent, non-phagocytic, relatively resistant to X-ray, and scarcely or only partially inacti...

journal_title：International journal of cancer

authors： Chang KS,Log T

更新日期：1980-03-15 00:00:00

abstract：:HER2 is an erbB/HER type 1 tyrosine kinase receptor that is frequently over-expressed in malignant epithelial tumours. Herceptin, a humanised mouse monoclonal antibody to HER2, is proven therapeutically in the management of metastatic breast cancer, significantly prolonging survival when combined with cytotoxic chemot...

journal_title：International journal of cancer

authors： Cox G,Vyberg M,Melgaard B,Askaa J,Oster A,O'Byrne KJ

更新日期：2001-05-15 00:00:00

abstract：:There are no reliable serologic tumor markers for transitional cell carcinoma (TCC) of the urinary bladder and noninvasive urine investigations are inadequate. We used fluorescent microsatellite analysis (MSA) to detect serum DNA and urine-sediment DNA alterations in patients with bladder cancer and prospectively coll...

journal_title：International journal of cancer

authors： von Knobloch R,Hegele A,Brandt H,Olbert P,Heidenreich A,Hofmann R

更新日期：2001-10-01 00:00:00

abstract：:Low ionic strength (50 to 100 mM NaCl) and pH 6.0 were found to be optimal conditions for in vitro conversion of Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA)-negative nuclei to EBNA-positive nuclei by addition of the complement-fixing (CF) antigen extracted from Raji cells. In vitro conversion of nuclei ...

journal_title：International journal of cancer

authors： Hirsch I,Suchánková A,Závadová H,Vonka V

更新日期：1978-11-15 00:00:00

abstract：:Leukocyte functions (superoxide production and phagocytosis) were evaluated in patients with testicular cancer who had undergone super-high-dose chemotherapy (SHDT) with peripheral blood stem cell transplantation (PBSCT). In 5 patients with advanced or relapsed testicular cancer who received 8 cycles of SHDT with PBSC...

journal_title：International journal of cancer

authors： Yamada Y,Hara I,Gohji K,Okada H,Arakawa S,Kamidono S

更新日期：1997-07-03 00:00:00

abstract：:We characterized 8 human hepatocellular-carcinoma cell lines established from the primary tumors of Korean patients. All lines showed substrate adherence and one line from anaplastic tumor also grew as floating aggregates. Most cultured cells maintained many morphological characteristics of the original tumors from wh...

journal_title：International journal of cancer

authors： Park JG,Lee JH,Kang MS,Park KJ,Jeon YM,Lee HJ,Kwon HS,Park HS,Yeo KS,Lee KU

更新日期：1995-07-28 00:00:00

abstract：:Colorectal (CRC) and gastric cancers (GC), the most common gastrointestinal malignancies, have been known to develop occasionally in a same patient. Previous studies have focused on the etiology of patients with multiple primary gastric and colorectal cancer (MPGCC); however, the carcinogenic process of MPGCC remains ...

journal_title：International journal of cancer

authors： Ohtani H,Yashiro M,Onoda N,Nishioka N,Kato Y,Yamamoto S,Fukushima S,Hirakawa-Ys Chung K

更新日期：2000-06-01 00:00:00

abstract：:Hormone refractory prostate cancer poses a huge problem and standard of care chemotherapy has not been very successful. We used a novel strategy to combine properties of 2 well-studied class of compounds (selenium and COX-2 inhibitor) and examined the resulting effectiveness against prostate cancer. Bearing in mind th...

journal_title：International journal of cancer

authors： Desai D,Sinha I,Null K,Wolter W,Suckow MA,King T,Amin S,Sinha R

更新日期：2010-07-01 00:00:00

abstract：:661 bp coding for the carboxyl end of the large sub-unit of EBV ribonucleotide reductase was cloned into the pMal plasmid vector. Purified recombinant protein was tested in IgG and IgA ELISAs. For the IgG assay, 81 out of 100 NPC patients tested positive, whereas for the IgA assay, 60 tested positive. Among 100 normal...

journal_title：International journal of cancer

authors： Fones-Tan A,Chan SH,Tsao SY,Gan LH,Tan WH,Li B,Khong PW,Gan YY

更新日期：1994-12-15 00:00:00

abstract：:In a retrospective analysis of 203 patients with small cell lung cancer (SCLC), we examined the prognostic value of c-kit expression on survival. Expression of c-kit was examined immunohistochemically in formalin-fixed, paraffin-embedded tissue sections. c-kit was observed in 87.7% of SCLC tumors. Using the Kaplan-Mei...

journal_title：International journal of cancer

authors： Rohr UP,Rehfeld N,Pflugfelder L,Geddert H,Müller W,Steidl U,Fenk R,Gräf T,Schott M,Thiele KP,Gabbert HE,Germing U,Kronenwett R,Haas R

更新日期：2004-08-20 00:00:00

abstract：:We previously reported identifying SOX6 as a glioma antigen by serological screening using a testis cDNA library. Its preferential expression and frequent IgG responses in glioma patients indicate that SOX6 may be a useful target for immunotherapy. To examine whether cytotoxic T-lymphocyte (CTL) responses specific for...

journal_title：International journal of cancer

authors： Ueda R,Kinoshita E,Ito R,Kawase T,Kawakami Y,Toda M

更新日期：2008-05-15 00:00:00

abstract：:We have previously demonstrated that the delta isoform of protein kinase C (PKCdelta) is importantly involved in cell growth inhibition and tumor suppression in colon cancer cells. To investigate further the activity and mechanism of action of PKCdelta, we have retrovirally transduced a PKCdelta cDNA in HCT116 human c...

journal_title：International journal of cancer

authors： Perletti G,Marras E,Dondi D,Osti D,Congiu T,Ferrarese R,de Eguileor M,Tashjian AH Jr

更新日期：2005-01-01 00:00:00

abstract：:The relationship between chemosensitivity and p53 is currently considered from two mutually exclusive points of view: (1) wt p53 increases chemosensitivity due to apoptosis and (2) wt p53 decreases chemosensitivity due to growth arrest and DNA repair. We used p53-expressing adenovirus (Ad-p53) to directly evaluate eff...

journal_title：International journal of cancer

authors： Blagosklonny MV,El-Deiry WS

更新日期：1998-03-16 00:00:00

abstract：:A herpesvirus (RhEBV) was isolated from a lymphoblastoid cell line (LCL) that became established from a malignant lymphoma in a rhesus monkey. The predominant cell marker in the LCL was that of B lymphocytes. RhEBV-induced viral capsid (VCA) and nuclear antigens (NA) in the LCL were serologically related to similar an...

journal_title：International journal of cancer

authors： Rangan SR,Martin LN,Bozelka BE,Wang N,Gormus BJ

更新日期：1986-09-15 00:00:00

abstract：:Micro RNAs (miR) are master regulators of cellular transcriptome. We aimed to investigate the role of miR regulation on tumor radiosensitivity and development of local tumor recurrence by a novel large-scale in vivo loss of function screen. For stable miR silencing, human A431 tumor cells were transduced with lentivir...

journal_title：International journal of cancer

authors： Fahim Golestaneh A,Lecker LSM,Schlegel J,Nowrouzi A,Schwager C,Meister S,Weichert W,Debus J,Abdollahi A

更新日期：2019-06-01 00:00:00

abstract：:We have shown in the preceding paper that AKR mice are highly resistant to M-MSV tumor development, and that resistance is transmitted as a dominant character. In the present studies the tumor-response pattern of F1 hybrids between resistant AKR and susceptible strains (C57Bl/6, BALB/c and B10BR) following injection w...

journal_title：International journal of cancer

authors： Colombatti A,Collavo D,Biasi G,Chieco-Bianchi L

更新日期：1975-09-15 00:00:00

abstract：:Cervical cancer is the second most common malignancy in women worldwide, with high risk subtypes of human papillomavirus (HPV) constituting the major etiological agent. However, only a small percentage of women infected by the virus develop disease, suggesting that additional host genetic alterations are necessary for...

journal_title：International journal of cancer

authors： Lockwood WW,Coe BP,Williams AC,MacAulay C,Lam WL

更新日期：2007-01-15 00:00:00

abstract：:A case-control study of 374 patients with primary epithelial cancers of the oral cavity, oro- and hypopharynx, and larynx is reported, the controls being patients with selected other cancers, matched for age and sex. Of all eligible patients, 93% were interviewed. Increased risks were seen with alcohol consumption and...

journal_title：International journal of cancer

authors： Elwood JM,Pearson JC,Skippen DH,Jackson SM

更新日期：1984-11-15 00:00:00

abstract：:Using a microarray technique, we found decorin to be underexpressed, but osteopontin (OPN) to be overexpressed, in esophageal squamous cell carcinoma (ESCC). This study aims to examine whether plasma decorin and OPN plus personal substances use (tobacco, alcohol and areca) can serve as suitable clinical markers to pre...

journal_title：International journal of cancer

authors： Wu IC,Wu DC,Huang CC,Lin HS,Chen YK,Tsai HJ,Lu CY,Chou SH,Chou YP,Li LH,Tai SY,Wu MT

更新日期：2010-11-01 00:00:00

abstract：:Our aim was to determine the long-term outcome and the possible role of neoadjuvant (preoperative) radiation therapy for breast cancers unsuitable for primary conservative surgery. From 1977 to 1992, 75 unifocal non-inflammatory and non-metastatic T2 and T3 breast cancers were treated in our department. All these pati...

journal_title：International journal of cancer

authors： Calitchi E,Kirova YM,Otmezguine Y,Feuilhade F,Piedbois Y,Le Bourgeois JP

更新日期：2001-08-20 00:00:00

abstract：:We report the inhibitory effect of 4-methylesculetin (ME), a 4-methylumbelliferone derivative, on hyaluronan (HA) synthesis by pancreatic cancer cells, and its resulting anticancer action. First, HA in cell culture was analyzed using competitive inhibition with hyaluronic acid-binding protein (HABP) to study HA synthe...

journal_title：International journal of cancer

authors： Hajime M,Shuichi Y,Makoto N,Masanori Y,Ikuko K,Atsushi K,Mutsuo S,Keiichi T

更新日期：2007-06-15 00:00:00

abstract：:Although adult obesity is known to increase endometrial cancer risk, evidence for childhood obesity is limited. We prospectively examined the association between body fatness throughout life and endometrial cancer risk. 47,289 participants in the Nurses' Health Study (NHS) and 105,386 of the Nurses' Health Study II (N...

journal_title：International journal of cancer

authors： Dougan MM,Hankinson SE,Vivo ID,Tworoger SS,Glynn RJ,Michels KB

更新日期：2015-08-01 00:00:00

abstract：:In a novel attempt to understand the variations in DNA sequences underlying HLA class I alleles associated with HPV16-related CaCx, we determined the alleles by reconstructing SNP-based haplotypes from resequencing of the most polymorphic exons 2 and 3 of HLA-A, HLA-B and HLA-C. We also determined the impact of SNPs a...

journal_title：International journal of cancer

authors： Das Ghosh D,Mukhopadhyay I,Bhattacharya A,Roy Chowdhury R,Mandal NR,Roy S,Sengupta S

更新日期：2017-06-01 00:00:00

abstract：:There is concern that hormone replacement therapy (HRT) increases the risk of breast cancer. We undertook a case-control study of this risk relationship within a cohort of 40- to 74-year-old women in Uppsala County, Sweden, who participated in mammography screening. Incident cases of breast cancer were ascertained dur...

journal_title：International journal of cancer

authors： Persson I,Thurfjell E,Bergstrom R,Holmberg L

更新日期：1997-09-04 00:00:00

abstract：:The serine protease urokinase-type plasminogen activator (uPA) plays a significant role in tumor cell invasion and metastasis when bound to its specific receptor, uPAR (also known as CD87). In addition to the uPA-uPAR system, matrix metalloproteinases (MMPs) are involved in tumor cell invasion and metastasis. In this ...

journal_title：International journal of cancer

authors： Kunigal S,Lakka SS,Gondi CS,Estes N,Rao JS

更新日期：2007-11-15 00:00:00

abstract：:The influence of polyunsaturated fatty acids (PUFAs) on risk of colorectal cancer precursors remains largely unknown. We examined the associations of erythrocyte PUFAs, including n-3 and n-6 PUFAs, with risk of colorectal conventional adenomas and serrated polyps in 4517 participants from three US prospective cohorts ...

journal_title：International journal of cancer

authors： Wang L,Hang D,He X,Lo CH,Wu K,Chan AT,Ogino S,Giovannucci EL,Song M

更新日期：2021-01-01 00:00:00

abstract：:We have investigated the effect of interferon-gamma (IFN-gamma) treatment of neuroblastoma cells on the susceptibility to lysis by lymphokine-activated killer (LAK) cells and examined the participation of cell-adhesion molecules on the target cells in LAK cell lysis. Untreated neuroblastoma cells expressed lymphocyte-...

journal_title：International journal of cancer

authors： Naganuma H,Kiessling R,Patarroyo M,Hansson M,Handgretinger R,Grönberg A

更新日期：1991-02-20 00:00:00

abstract：:An antigen, protein X (Px), was purified from immune complexes isolated from malignant pleural effusions from patients with adenocarcinoma of the lung by EDTA treatment, PEG 8000 precipitation, protein A affinity chromatography, and Sephadex G-200 separation in the presence of 3 M NaCl. The purified antigen had a M(r)...

journal_title：International journal of cancer

authors： Zeng CQ,Alpert LC,Alpert E

更新日期：1992-10-21 00:00:00

abstract：:The interactions of MCF-7 tumor cells with human vascular endothelial cells (EC) and subendothelial extracellular matrices (ECM) were morphologically observed by electron microscopy and quantitatively evaluated by labelling tumor cells with 111Indium-oxine. MCF-7 tumor cells adhered more rapidly to ECM than to the api...

journal_title：International journal of cancer

authors： Abecassis J,Millon-Collard R,Klein-Soyer C,Nicora F,Fricker JP,Beretz A,Eber M,Muller D,Cazenave JP

更新日期：1987-10-15 00:00:00