Characterization of cell lines established from human hepatocellular carcinoma.

abstract：:A case-control study of prostate cancer (PC) was undertaken in Athens, Greece. Cases were 320 patients with histologically confirmed incident disease, whereas controls were 246 patients without history or symptomatology of benign prostatic hyperplasia, treated in the same hospitals as the cases for minor diseases or c...

journal_title：International journal of cancer

authors： Hsieh CC,Thanos A,Mitropoulos D,Deliveliotis C,Mantzoros CS,Trichopoulos D

更新日期：1999-03-01 00:00:00

abstract：:Factors related to energy metabolism and the metabolic syndrome, such as higher body mass index (BMI), blood glucose, or blood lipids, and blood pressure, are associated with an increased risk of colorectal cancer (CRC). However, CRC is a heterogeneous disease, developing through distinct pathways with differences in ...

journal_title：International journal of cancer

authors： Myte R,Gylling B,Häggström J,Häggström C,Zingmark C,Löfgren Burström A,Palmqvist R,Van Guelpen B

更新日期：2019-07-15 00:00:00

abstract：:Treatment of older mice with pyran copolymer, a known interferon-inducer, was found to result in a rapid boosting of cell-mediated cytolytic activity against YAC-1 tumor target cells. The effector cells were characterized as being non-adherent and were presumed to be natural killer (NK) cells. Augmentation occurred in...

journal_title：International journal of cancer

authors： Santoni A,Puccetti P,Riccardi C,Herberman RB,Bonmassar E

更新日期：1979-11-15 00:00:00

abstract：:The topic of this review is the role of stromal-epithelial interactions in normal and malignant prostatic growth. Because cell-cell interactions and androgens play such key roles in the prostate, the goal of this review will be to apply endocrinologic and developmental concepts to the understanding of normal and malig...

journal_title：International journal of cancer

authors： Cunha GR,Hayward SW,Wang YZ,Ricke WA

更新日期：2003-10-20 00:00:00

abstract：:G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells. However, its role in breast cancer stem cells (BCSCs) remains unclear. Here we showed greater expression of GPER in BCSCs...

journal_title：International journal of cancer

authors： Chan YT,Lai AC,Lin RJ,Wang YH,Wang YT,Chang WW,Wu HY,Lin YJ,Chang WY,Wu JC,Yu JC,Chen YJ,Yu AL

更新日期：2020-03-15 00:00:00

abstract：:Of 6- and 3-week-old nude mice given intravenous injections of murine tumor cells with well-defined metastatic properties, only the 3-week-old mice developed lung tumor colonies in significant numbers. The quantitative differences in metastatic potential among tumor cell lines injected into syngeneic recipients were a...

journal_title：International journal of cancer

authors： Hanna N

更新日期：1980-11-15 00:00:00

abstract：:Oncogenic HPV types are the major cause of worldwide cervical cancer, but only a small proportion of infected women will develop high-grade cervical intraepithelial neoplasia or cancer (CIN2/3+). We performed a prospective study including 781 women with normal, atypical squamous cells of undetermined significance (ASC...

journal_title：International journal of cancer

authors： Dalstein V,Riethmuller D,Prétet JL,Le Bail Carval K,Sautière JL,Carbillet JP,Kantelip B,Schaal JP,Mougin C

更新日期：2003-09-01 00:00:00

abstract：:A panel of monoclonal antibodies and other markers (e.g., terminal deoxynucleotidyl transferase, sheep erythrocyte rosettes, peanut agglutinin) have been used in conjunction with flow cytometry and biochemical analysis to monitor the induction of maturation in human thymic (T) leukaemic cell lines by phorbol ester (TP...

journal_title：International journal of cancer

authors： Delia D,Greaves MF,Newman RA,Sutherland DR,Minowada J,Kung P,Goldstein G

更新日期：1982-01-15 00:00:00

abstract：:Obesity is a well-known risk factor for postmenopausal breast cancer. In contrast, the relationship between obesity and stage of breast cancer at diagnosis is less clear. We hypothesized that increased breast size in obese women may delay discovery of breast tumors. Thus, the purpose of our study was to examine whethe...

journal_title：International journal of cancer

authors： Cui Y,Whiteman MK,Flaws JA,Langenberg P,Tkaczuk KH,Bush TL

更新日期：2002-03-10 00:00:00

abstract：:EMT6 is a transplantable mouse mammary tumor cell line that has been utilized widely as a model system to study the effects of various treatments on local tumor growth and pulmonary metastasis. In this study, we examined the cellular mechanisms by which scatter factor (SF), a fibroblast-derived cytokine that stimulate...

journal_title：International journal of cancer

authors： Rosen EM,Knesel J,Goldberg ID,Jin L,Bhargava M,Joseph A,Zitnik R,Wines J,Kelley M,Rockwell S

更新日期：1994-06-01 00:00:00

abstract：:Using a direct binding liquid competition radioimmunoassay, the amount of the ras oncogene protein product, p21, was quantitated in a variety of human tumors and adjacent apparently normal tissues. In 48 of 50 matched tumor and normal tissue biopsy specimens from 50 patients, more ras p21 was detected in the tumor tha...

journal_title：International journal of cancer

authors： De Biasi F,Del Sal G,Hand PH

更新日期：1989-03-15 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Emerging evidence indicates that tumour cells release substantial amounts of RNA into the bloodstream, in which RNA strongly resists RNases and is present at sufficient levels for quantitative analyses. ...

journal_title：International journal of cancer

authors： Xu W,Zhou G,Wang H,Liu Y,Chen B,Chen W,Lin C,Wu S,Gong A,Xu M

更新日期：2020-05-15 00:00:00

abstract：:HNPCC is an autosomal dominantly inherited cancer-susceptibility syndrome that confers an increased risk for colorectal cancer and endometrial cancer at a young age. It also entails an increased risk of a variety of other tumors, such as ovarian, gastric, uroepithelial and biliary tract cancers. The underlying pathoge...

journal_title：International journal of cancer

authors： Caldes T,Godino J,de la Hoya M,Garcia Carbonero I,Perez Segura P,Eng C,Benito M,Diaz-Rubio E

更新日期：2002-04-10 00:00:00

abstract：:The Eph receptor A2 (EphA2) is overexpressed in a range of human epithelial cancers, a phenotype that is associated with cancer cell proliferation, progression and angiogenesis. Mouse models of mammary neoplasia have confirmed the role of EphA2 as mice carrying a knockout allele of EphA2 were resistant to breast cance...

journal_title：International journal of cancer

authors： Bogan C,Chen J,O'Sullivan MG,Cormier RT

更新日期：2009-03-15 00:00:00

abstract：:Experimental and epidemiological evidence supports a role for sex steroid hormones in the pathogenesis of ovarian cancer. We investigated the association between ovarian cancer risk and pre-diagnostic blood concentrations of testosterone, androstenedione, DHEAS, estrone and SHBG. A case-control study nested within 3 c...

journal_title：International journal of cancer

authors： Lukanova A,Lundin E,Akhmedkhanov A,Micheli A,Rinaldi S,Zeleniuch-Jacquotte A,Lenner P,Muti P,Biessy C,Krogh V,Berrino F,Hallmans G,Riboli E,Kaaks R,Toniolo P

更新日期：2003-05-01 00:00:00

abstract：:Cancer-related cachexia is a metabolic syndrome characterized by a wasting disorder of adipose and skeletal muscle and is accompanied by body weight loss and systemic inflammation. The treatment options for cancer cachexia are limited, and the molecular mechanism remains poorly understood. Circular RNAs (circRNAs) are...

journal_title：International journal of cancer

authors： Zhang H,Zhu L,Bai M,Liu Y,Zhan Y,Deng T,Yang H,Sun W,Wang X,Zhu K,Fan Q,Li J,Ying G,Ba Y

更新日期：2019-05-15 00:00:00

abstract：:BALB/c peritoneal plasmacytomas induced by a variety of agents are invariably associated with a c-myc translocation. In contrast, naturally arising bone marrow plasma cell tumors in C57BL/KaLwRij mice lack this translocation. This difference has led to the suggestion that these are 2 fundamentally different plasma cel...

journal_title：International journal of cancer

authors： Pumphrey JG,Hausner P,Rudikoff S

更新日期：1997-09-04 00:00:00

abstract：:Aberrant promoter methylation of normally unmethylated CpG-islands offers a promising tool for the development of molecular biomarkers. We investigated bronchial aspirates of patients admitted for suspected lung cancer with regard to the prevalence of aberrant methylation of potential marker genes. Applying quantitati...

journal_title：International journal of cancer

authors： Grote HJ,Schmiemann V,Geddert H,Rohr UP,Kappes R,Gabbert HE,Böcking A

更新日期：2005-09-20 00:00:00

abstract：:An automated fluorometric microculture cytotoxicity assay (FMCA) based on the measurement of fluorescence generated from cellular hydrolysis of fluorescein diacetate (FDA) to fluorescein was employed for chemotherapeutic-drug-sensitivity testing of tumor-cell suspensions from patients with leukemia. Fluorescence was l...

journal_title：International journal of cancer

authors： Larsson R,Kristensen J,Sandberg C,Nygren P

更新日期：1992-01-21 00:00:00

abstract：:China was one of the countries with the highest esophagus cancer risk in the world during the 1970s. This report provides data on time trends of esophagus cancer incidence and mortality during the 1970s-90s in selected geographic areas of China. Information on newly diagnosed cancer cases and cancer deaths is based on...

journal_title：International journal of cancer

authors： Ke L

更新日期：2002-11-20 00:00:00

abstract：:Telomerase plays a key role in carcinogenesis. It is activated in most immortal cell lines and human cancers, including cutaneous melanoma (CM). Increased cell proliferation and deregulation of the cell cycle occur in human cancers. Links between telomerase activity (TA), cell proliferation, cell death and expression ...

journal_title：International journal of cancer

authors： Miracco C,Pacenti L,Santopietro R,Biagioli M,Fimiani M,Perotti R,Rubegni P,Pirtoli L,Luzi P

更新日期：2000-11-01 00:00:00

abstract：:Metastasis-associated protein MTA1 and histone deacetylase form a protein complex with histone deacetylase activity that plays an important role in histone deacetylation, alteration of chromatin structure and transcriptional control. The precise role of the MTA1 protein in the malignant progression of human cancers re...

journal_title：International journal of cancer

authors： Toh Y,Ohga T,Endo K,Adachi E,Kusumoto H,Haraguchi M,Okamura T,Nicolson GL

更新日期：2004-06-20 00:00:00

abstract：:To estimate the annual incidence of adult T-cell leukemia/lymphoma (ATL) by district in Japan, a large-scale nationwide survey of ATL and of non-Hodgkin's lymphoma was performed in 1988. Questionnaires for the registration of ATL and of T-cell and non-T-cell lymphoma were distributed to the physicians in charge of thi...

journal_title：International journal of cancer

authors： Tajima K

更新日期：1990-02-15 00:00:00

abstract：:A loss of chromosome-9 material is one of the most frequent genomic aberrations known in bladder cancer. In order to better understand the role of chromosome-9 losses in bladder cancer, 125 formalin-fixed and 37 unfixed bladder tumors were examined using fluorescence in situ hybridization (FISH). A repetitive probe fo...

journal_title：International journal of cancer

authors： Sauter G,Moch H,Carroll P,Kerschmann R,Mihatsch MJ,Waldman FM

更新日期：1995-04-21 00:00:00

abstract：:Osteosarcoma incidence rates in the United States peak in adolescence and in the elderly. The international patterns of osteosarcoma incidence in children have been described, whereas those for young, middle age or elderly adults have not. Using the Cancer Incidence in Five Continents, International Agency for Cancer ...

journal_title：International journal of cancer

authors： Mirabello L,Troisi RJ,Savage SA

更新日期：2009-07-01 00:00:00

abstract：:We have previously shown that anti-Ly-6C monoclonal antibody (MAb) 2B6-F2 identifies a subset of (CBA +/- C57BL/6)F1 splenic NK-1.1+ natural T (NT) cells which kill the NK-sensitive YAC-1 target in vitro. Furthermore, these Ly-6C+ cells are responsible for 40-50% of in vitro YAC-1 killing in all mouse strains tested. ...

journal_title：International journal of cancer

authors： Martiniello R,Burton RC,Smart YC

更新日期：1996-05-16 00:00:00

abstract：:Oral leukoplakia is a heterogeneous lesion with risk of cancer development; there are no biomarkers to predict its potential of malignant transformation. Tissue proteomic analysis of oral leukoplakia using iTRAQ labeling liquid chromatography-mass spectrometry showed overexpression of heterogeneous ribonucleoprotein K...

journal_title：International journal of cancer

authors： Matta A,Tripathi SC,DeSouza LV,Grigull J,Kaur J,Chauhan SS,Srivastava A,Thakar A,Shukla NK,Duggal R,DattaGupta S,Ralhan R,Michael Siu KW

更新日期：2009-09-15 00:00:00

abstract：:Adherent cells with the ability to inhibit NK activity were found in the spleens of young 8-week-old SJL/J mice. Such suppressor cells were also found in the spleens of other low-NK-reactive strains, but not in the spleen of age-matched high-NK-reactive strains. These suppressor cells had the characteristics of macrop...

journal_title：International journal of cancer

authors： Riccardi C,Santoni A,Barlozzari T,Cesarinin C,Herberman RB

更新日期：1981-12-01 00:00:00

abstract：:Peripheral blood leukocytes from patients with confirmed pulmonary neoplasia were tested for cytotoxicity against cultured cells derived from lung tumours of various histological types, foetal and normal adult lung tissue and tumours arising in organs other than the lung. Leukocytes from 73 percent of patients were cy...

journal_title：International journal of cancer

authors： Vose BM,Moore M,Jack GD

更新日期：1975-02-15 00:00:00

abstract：:Immunogenicity of a long 20-mer NY-ESO-1f peptide vaccine was evaluated in a lung cancer patient TK-f01, immunized with the peptide with Picibanil OK-432 and Montanide ISA-51. We showed that internalization of the peptide was necessary to present CD8 T-cell epitopes on APC, contrasting with the direct presentation of ...

journal_title：International journal of cancer

authors： Eikawa S,Kakimi K,Isobe M,Kuzushima K,Luescher I,Ohue Y,Ikeuchi K,Uenaka A,Nishikawa H,Udono H,Oka M,Nakayama E

更新日期：2013-01-15 00:00:00